Gene Details:

  • Gene ID: AA31G00448
  • Gene Family: BES1 Family
  • Description: BES1 Family protein
  • Species: Aethionema arabicum
  • Source: BES1 family gene from PlantTFDB

Protein Features:

Annotation Proteins:

  • Refseq:  XP_020889991.1  — protein BRASSINAZOLE-RESISTANT 1
  • Swissprot:  Q8S307  — BZR1_ARATH; Protein BRASSINAZOLE-RESISTANT 1
  • TrEMBL:  D7KSK2  — D7KSK2_ARALL; At1g75080/F9E10_7
  • STRING:  Bostr.3288s0155.1.p  — (Boechera stricta)

Gene Ontology:

  • GO:0009742  — Biological Process — brassinosteroid mediated signaling pathway
  • GO:0045892  — Biological Process — negative regulation of transcription, DNA-templated
  • GO:0048316  — Biological Process — seed development
  • GO:0048481  — Biological Process — plant ovule development
  • GO:0005634  — Cellular Component — nucleus
  • GO:0005829  — Cellular Component — cytosol
  • GO:0003677  — Molecular Function — DNA binding
  • GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding

Family Introduction:

  • Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo.
  • BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Literature:

Sequences:

CDS Sequence:
  • >AA31G00448|Aethionema_arabicum|BES1|AA31G00448
    ATGACGTTGGATGGAGCTACGTCGACATCAGCAGCTGCGGCGGCGGCAGCAGCGGCGAGGAGGAAACCATCGTGGAGGGAGAGGGAGAATAATCGGAGGAGAGAGAGACGGAGAAGAGCTGTAGCTGCTAAGATATATACTGGACTTAGAGCTCAAGGTGATTATAATCTCCCTAAACACTGCGATAACAATGAGGTGCTTAAGGCTCTTTGTGCTGAAGCTGGTTGGGTTGTAGAAGAAGATGGAACCACGTATCGCAAGTATCAGGGATGCAAGCCTCTACCTGGTGACATAGCTGGGACTTCATCTCGAGTGACTCCATACTCATCTCAGAACCTGAGTCCTCTTTCATCAGCCTTCCAGAGCCCCATTCCATCTTACCAAGTCAGCCCATCGTCGTCGTCTTTCCCGAGTCCTTCTCGTGTTGAACCAAACAACATCTCCACATTCTTCCCTTTCCTCAGAAATGGTGGCATTCCTTCATCTCTTCCTTCTCTCAGAATCTCAAACAGTTGTCCTGTTACTCCACCAGTCTCATCTCCAACTTCTAAAAACCCTAAACCATTACCTAATTGGGATTCAATTGCTAAGCAATCAATGGCTATTGCTAAACAATCAATGTCATCTTTTAATTATCCATTTTATGCAGCTTCTGCACCTGCTAGTCCAACCCATCGTCAGTTTCATACCCCAGCTACTATACCTGAATGTGATGAGTCTGACTCTTCTACCGTTGACTCTGGTCACTGGATAAGCTTTCAAAAGTTCACACAACAACCATTTCCTACCTCCATGGTTCCAACCTCTCCCACCTTTAATCTTGTAAAACCTGCACCTCAACAGATGTCCCCAAACGCTGCGTTGCAAGAGATTGGTCAAAGCTCTGAATTCAAATTCGAGAATAGCCAAGTTAAACCATGGGAAGGGGAAAGGATACACGACGTGGGTATGGAAGATCTAGAGCTTACACTCGGAAACCGGAAGAAAGCTCGTGGT
Protein Sequence:
  • >AA31G00448|Aethionema_arabicum|BES1|AA31G00448
    MTLDGATSTSAAAAAAAAARRKPSWRERENNRRRERRRRAVAAKIYTGLRAQGDYNLPKHCDNNEVLKALCAEAGWVVEEDGTTYRKYQGCKPLPGDIAGTSSRVTPYSSQNLSPLSSAFQSPIPSYQVSPSSSSFPSPSRVEPNNISTFFPFLRNGGIPSSLPSLRISNSCPVTPPVSSPTSKNPKPLPNWDSIAKQSMAIAKQSMSSFNYPFYAASAPASPTHRQFHTPATIPECDESDSSTVDSGHWISFQKFTQQPFPTSMVPTSPTFNLVKPAPQQMSPNAALQEIGQSSEFKFENSQVKPWEGERIHDVGMEDLELTLGNRKKARG