Gene Details:

• Gene ID: Aqcoe7G362900.2.p
• Gene Family: ARR-B Family
• Description: ARR-B Family protein
• Species: Aquilegia coerulea
• Source: ARR-B family gene from PlantTFDB

Protein Features:

• SuperFamily:  SSF52172
• Gene3D:  G3DSA:3.40.50.2300
• SMART:  SM00448
• PROSITE profile:  PS50110
• Pfam:  PF00072
• SuperFamily:  SSF46689
• Gene3D:  G3DSA:1.10.10.60
• TIGRFAMs:  TIGR01557
• Pfam:  PF00249
• InterPro:  IPR011006    IPR001789    IPR009057    IPR006447    IPR001005

Annotation Proteins:

• Refseq:  XP_010275724.1  — PREDICTED: two-component response regulator ORR24-like
• Swissprot:  Q6K8X6  — ORR23_ORYSJ; Two-component response regulator ORR23
• TrEMBL:  A0A2G5DQF0  — A0A2G5DQF0_AQUCA; Uncharacterized protein
• STRING:  Aquca_016_00168.1  — (Aquilegia coerulea)

Gene Ontology:

• GO:0000160  — Biological Process — phosphorelay signal transduction system
• GO:0009414  — Biological Process — response to water deprivation
• GO:0010082  — Biological Process — regulation of root meristem growth
• GO:0010380  — Biological Process — regulation of chlorophyll biosynthetic process
• GO:0031537  — Biological Process — regulation of anthocyanin metabolic process
• GO:0045893  — Biological Process — positive regulation of transcription, DNA-templated
• GO:0048367  — Biological Process — shoot system development
• GO:0080022  — Biological Process — primary root development
• GO:0080036  — Biological Process — regulation of cytokinin-activated signaling pathway
• GO:0080113  — Biological Process — regulation of seed growth
• GO:0005634  — Cellular Component — nucleus
• GO:0003700  — Molecular Function — transcription factor activity, sequence-specific DNA binding
• GO:0043565  — Molecular Function — sequence-specific DNA binding

Family Introduction:

• The Arabidopsis genome codes for 22 response regulators (ARRs), 12 of which contain a Myb-like DNA binding domain called ARRM (type B). The remainder (type A) possess no apparent functional unit other than a signal receiver domain containing two aspartate and one lysine residues (DDK) at invariant positions, and their genes are transcriptionally induced by cytokinins without de novo protein synthesis. The type B members, ARR1 and ARR2, bind DNA in a sequence-specific manner and work as transcriptional activators.
• Here we present evidence that ARR1 mediates a cytokinin signal, probably through its NH2-terminal signal receiver domain, and transactivates ARR6, which is immediately responsive to cytokinins. A paralogous response regulator, ARR2, shows almost identical characteristics to ARR1, suggesting a functional overlap. Residual cytokinin responses observed with the arr1-1 mutant may have been provided by ARR2. In addition to ARR6, other type A member genes, including ARR4, ARR5, ARR7, ARR8, and ARR9, were also activated by DEX at various levels in 35S::ARR1DDK::GR plants, suggesting that all the immediate cytokinin-responsive genes belonging to this group are directly activated by ARR1. Also, other cytokinin-responsive genes whose promoter regions contain the ARR1 recognition sequences are possibly transactivated by ARR1. A screening for ARR1 target genes using transgenic 35S::ARR1-DDK::GR plants will shed light on the whole view of the early cytokinin signal transduction pathway. We conclude that ARR1 is a principal transcription factor-type response regulator that is involved in an early step of cytokinin signal transduction, possibly as a partner of the sensor histidine kinase CRE1.

Literature:

• ARR1, a Transcription Factor for Genes Immediately Responsive to Cytokinins.   DOI:  10.1126/science.1065201 ;  PMID:  11691951

Sequences: