Information report for Cla019321
Gene Details
Functional Annotation
- Refseq: XP_008464365.1 — PREDICTED: auxin response factor 2
- Refseq: XP_008464366.1 — PREDICTED: auxin response factor 2
- Swissprot: Q2LAJ3 — ARF2A_SOLLC; Auxin response factor 2A
- TrEMBL: A0A1S3CLA6 — A0A1S3CLA6_CUCME; Auxin response factor
- TrEMBL: E5GBL7 — E5GBL7_CUCME; Auxin response factor
- STRING: XP_008464365.1 — (Cucumis melo)
- GO:0008285 — Biological Process — negative regulation of cell proliferation
- GO:0009737 — Biological Process — response to abscisic acid
- GO:0009911 — Biological Process — positive regulation of flower development
- GO:0010047 — Biological Process — fruit dehiscence
- GO:0010150 — Biological Process — leaf senescence
- GO:0010227 — Biological Process — floral organ abscission
- GO:0045892 — Biological Process — negative regulation of transcription, DNA-templated
- GO:0048481 — Biological Process — plant ovule development
- GO:0005634 — Cellular Component — nucleus
- GO:0005515 — Molecular Function — protein binding
- GO:0043565 — Molecular Function — sequence-specific DNA binding
Family Introduction
- Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.
- Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.
- The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.
Literature and News
- Auxin response factors. DOI: 10.1016/j.pbi.2007.08.014 ; PMID: 17900969
Gene Resources
Sequences
CDS Sequence:
- >Cla019321|Citrullus_lanatus|ARF|Cla019321
ATGGCCTCCTCCGAGGTTTCGATCAACCCCAATTCCGCCTCCTTCAACGACCATACCGATTCTACCAAAGACACCTCCGATCCACCCAACGCTCTCTCTGTCAGGGATGCTGATATCGCCCTCTACACCGAGCTTTGGAATGCTTGTGCTGGCCCTCTCGTTTCGGTTCCTCGCGAAAACGAGCGCGTCTTCTACTTCCCTCAGGGCCACATCGAACAGGTGGAAGCATCAACAAGTCAAGTGGCAGACCAGCAGATGCCTGTATATAACCTTCCATGGAAGATCCTCTGCCGCGTTATTAATGTGCACTTAAAGGCCGAACCGGACACTGATGAGGTATTTGCACAAATAACTTTGCTTCCAGAGGCTAATCAAGATGAGAATGCTGTGGACAAGGAACCCCCACCTCCTCCCCCGCGGAGATTTCATGTGCATTCCTTTTGCAAGACTCTGACTGCCTCTGACACCAGTACTCATGGGGGGTTTTCAGTCTTGAGACGCCATGCTGATGAATGTCTTCCACCACTGGACATGTCACGACAGCCTCCTACTCAGGAGTTGGTTGCAAAGGATTTGCATGGAACAGAATGGCGTTTTCGTCATATATTTCGAGGGCAACCGCGTAGGCATTTGCTTCAGAGTGGTTGGAGTGTTTTCGTGAGCTCAAAAAGACTGGTTGCAGGAGATGCTTTTATATTCTTGAGGGGTGAGAATGGAGAACTGCGCGTTGGTGTAAGGCGTGCCATGAGACAACATGGCAACGTCCCATCATCGGTCATATCTAGCCATAGCATGCATCTTGGTGTGCTTGCAACTGCTTGGCATGCTATTTCCACAGGCACAATGTTCACTGTCTACTATAAACCTAGGACTAGCCCTTCTGAATTCATTGTTCCATATGACCAGTATATGGAGTCTATTAAGAAGAGCTACACCATTGGAATGCGGTTCAAAATGAGATTTGAAGGTGAAGAGGCTCCTGAACAGAGATTCACGGGTACTATCATTGGATGTGAAGATGCTGATCCCAAAAGGTGGAAAGATTCCAAGTGGAGATGCCTGAAGGTGAGATGGGACGAGACTTCTACTATTTCTCGTCCGGAGAAAGTTTCACCATGGAAAATTGAGCCTGCCCTTGCTCCTCCTGCACTGAACCCCCTTCCTATGACTAGACCTAAGAGGCCTCGATCAAATATGGTATCTACATCCCCCGATTCCTCTGTTCTTACACGAGAAGGTTCATCAAGAGTGACTGTAGACCCTTCACCAGCCAGTGCATTTACAAGGGTCTTGCAAGGTCAAGAATTCTCGACCTTGAGAGGCAATTTTATCGATAGTAATGATCCAGATGCTGCTGAAAAATCTGTTATGTGGCCTCCTTCACTAGATGATGAGAAAATTGATGTGGTTTCTACGTCTAAGAAACATGGAGCAGATAGCTGGATACCACCTCCAGGAAGGAGTGAGCCAACTTATGCCGATCTTCTGTCAGGTTTTGGAACTAATATTGATTCATCTCATGGTGTTCGAGCTGGCATGGGAGATTCAGCAGTAGTCACTGTTAATTCAATCAGAAAGCATGCCATGGATCAAGATGGAAAGTTTAACTTCCTTGGTGGTAGCTCATGGTCTGCCTTGCCTTCTGGTCTCTCGCTCAACCTGGTTGACTCTAGTCAGAGGGGTCATATTCAGGCTGGTGACTTATCTTATCAAGGGAGAGGAAATGCTACCTTCAATGGATTTGGTGATCATTCCATGGCCCATTGTCATAGAACAGAACAGCCTCATGGAAACTGGTTGATGCCTCCACCTTCATCTCATTTTGACTATCCAGTTCATTCAACTGAACTGATGTCAAAACCTATATTATTTCAGAACCAAGATATACTGAAACCCAAAGATGGGAATTGTAAGCTTTTTGGCATCTCTCTCAATAAAAATCCTGCCATTCCAGACCCTGCAGGACTGAGTAGAAATATGATGAACGAGGCAGCAGATGTTATGCATCCTAATATACATCAAATCCATTCAAACGAGTCTGACCTGAAGGCTGAACTATCTAGAGGTTCAAAATTGGCTGATAAATCCCTTGCCATCAATGAGGCTGATAAGTTGCAGCAACCATGCGCACATAACTCGAAGGACACACACAGCAAATCACAGGGTACTTCAGCAAGGAGTTGTACAAAGGTCCACAAGCAGGGGATTGCACTTGGAAGGTCAGTTGATCTTAGCAGGTTCAACAATTACGATGAATTGGTTGCTGAATTGGACCAACTGTTTGAATTTGGTGGTGAGCTGCTGGCTCCCAAAAAGAAATGGCTTATTGTATATACGGATGATGAAGGTGATATGATGCTTGTTGGAGACGATCCCTGGCAGGAGTTTTGTGGTATGGTTCGGAAGATTTTTATCTATACAAGAGAAGAGGTCCAGAAGATGAATCCAGGATCCCTAAATTTAAAAGGTGATGAGAATCCATCCATTGAAGGGGAAGAAGCAAAAGAGATCAAAAGTCAGGCAGTACCTTCGATGTCAGTACCCGAGAGTTCTTAG
Protein Sequence:
- >Cla019321|Citrullus_lanatus|ARF|Cla019321
MASSEVSINPNSASFNDHTDSTKDTSDPPNALSVRDADIALYTELWNACAGPLVSVPRENERVFYFPQGHIEQVEASTSQVADQQMPVYNLPWKILCRVINVHLKAEPDTDEVFAQITLLPEANQDENAVDKEPPPPPPRRFHVHSFCKTLTASDTSTHGGFSVLRRHADECLPPLDMSRQPPTQELVAKDLHGTEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFLRGENGELRVGVRRAMRQHGNVPSSVISSHSMHLGVLATAWHAISTGTMFTVYYKPRTSPSEFIVPYDQYMESIKKSYTIGMRFKMRFEGEEAPEQRFTGTIIGCEDADPKRWKDSKWRCLKVRWDETSTISRPEKVSPWKIEPALAPPALNPLPMTRPKRPRSNMVSTSPDSSVLTREGSSRVTVDPSPASAFTRVLQGQEFSTLRGNFIDSNDPDAAEKSVMWPPSLDDEKIDVVSTSKKHGADSWIPPPGRSEPTYADLLSGFGTNIDSSHGVRAGMGDSAVVTVNSIRKHAMDQDGKFNFLGGSSWSALPSGLSLNLVDSSQRGHIQAGDLSYQGRGNATFNGFGDHSMAHCHRTEQPHGNWLMPPPSSHFDYPVHSTELMSKPILFQNQDILKPKDGNCKLFGISLNKNPAIPDPAGLSRNMMNEAADVMHPNIHQIHSNESDLKAELSRGSKLADKSLAINEADKLQQPCAHNSKDTHSKSQGTSARSCTKVHKQGIALGRSVDLSRFNNYDELVAELDQLFEFGGELLAPKKKWLIVYTDDEGDMMLVGDDPWQEFCGMVRKIFIYTREEVQKMNPGSLNLKGDENPSIEGEEAKEIKSQAVPSMSVPESS