Gene Details:

Functional Descriptions:

  • SlCK2α as a novel substrate for CRL4 E3 ligase (SlCDK2) regulates fruit size through maintenance of cell division homeostasis in tomato
  • This study unravels a novel regulatory module (CRL4-CK2α-CDK2) involving fruit size control by mediating cell division homeostasis (SlCK2α and SlCDK2) in tomato.
  • A tomato homolog of cell division protein kinase 2 (SlCDK2) could interact with and specifically be phosphorylated by SlCK2α, resulting in an increase of SlCDK2 protein stability.
  • CRISPR/Cas9-based genetic evidence showed that SlCDK2 is also a positive regulator of fruit size by influencing cell division in tomato.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >Solyc11g070140.2.1
    GTGATTCCAGTCCAAAACGGTTCTACGGCGGCATTTTCTCTCTTTCTCCCGCCACAATCACCGCTGCTTCTCATCTCCGATCATCCGCGTAACGACGGCAAGTTCTTCATCTCCGCCGTACTAAGGTGAATGTGAAACAGTTTACTGATCGACTCGTTTTCTCCACTCACATTTGCCTCTTTTCTCCTGAATTCTATCCATTTCATAATATTATACACACAGATGTAACAGTAGATTTCTTCTCTCTGGATTCATCCATATTGACCTAGATGGACCAGTATGAAAAAATTGGGAAGATTGGGGAAGGAACATATGGTGTAGTGTACAAGGCCTTCGTTCGTGAAACCAAGGAAATCGTTGCTCTAAAAAAAATACGGCTGGAACAAGAAGATGAGGGAGTGCCTAGCACAGCTATAAGAGAAATTTCTCTTTTAAAAGAGATGCAGCACGGAAATATTGTGAGGTTGCTGGATGTGGTTCACAGTGAGAGGCGATTATATTTAGTCTTTGAATATCTTGACTTGGATTTGAAGAAGCACATGGATTCATGTCCTGAATTCTCTAAGGATACCGGTGTTGTAAAATCGTTTGTGTATCAAATGCTCCGTGGTCTTGCTTATTGTCATTCTCGTAGAGTTCTCCACAGAGATCTAAAGCCTCAGAATTTGCTGATAGATCCACGCACCAATGTGTTAAAGCTTGCAGATTTTGGATTGGGTAGAGCATTTGGTATTCCTGTTAGAACTTTTACTCATGAGGTGGTGACATTATGGTACAGGGCACCAGAAATACTGCTTGGATCAAGGCACTACTCTACTCCGGTTGATGTGTGGTCGGCTGGTTGCATATTTGCCGAGATGGTTAACCAGCAGCCCCTTTTTCCTGGTGACTCAGAGATTGATGAACTTTTCAGCATTTTCAGAGTGGTGGGTACTCCAAATGAGAATACATGGCCTGGAGTGACTTCTTTGCCTGATTATAAATCTTCATTTCCAAAATGGAGTCCTAAGGATCTGGCAACTTTAGTCCCGAATCTTGATACTGCAGGATTTGATCTCCTTGGTAAAATGCTCTGCTTGGACCCCAGCAAGAGAATCACTGCCAAAAGTGCCCTTGAACATGAGTATTTCAAGGATATTGGCCGTGTTCGATGACTCTTTGCATCTTCATCAACAACGTGAGCACAACTTGGTTCATTAGCATTCATACTTCTGCAAGGACTCGCTGAATTACTGGTCATTGCTGTGCGTTTCAATTTTTTTGCGTAGCTTGATACTGGCATTGAAGAACGAGATGATGATCCGCATAGTCAGTTATACATGATTACTATTCCTGGAGGAATGCAGGCTACAGTTCAGGTTTACCAAGTTATGTTTTGATACTGTATGAATTTTTTTTTCTTGGTCTGACAATAGAGAGTCTGGCCTCTCAATATTCAGGACTCTCCAAAAACTTCTGCTATTTTGATAGGAAAATCATGGAAGGCTAAAATAGTTGATCATAGCAA
CDS Sequence
  • >Solyc11g070140.2.1
    ATGGACCAGTATGAAAAAATTGGGAAGATTGGGGAAGGAACATATGGTGTAGTGTACAAGGCCTTCGTTCGTGAAACCAAGGAAATCGTTGCTCTAAAAAAAATACGGCTGGAACAAGAAGATGAGGGAGTGCCTAGCACAGCTATAAGAGAAATTTCTCTTTTAAAAGAGATGCAGCACGGAAATATTGTGAGGTTGCTGGATGTGGTTCACAGTGAGAGGCGATTATATTTAGTCTTTGAATATCTTGACTTGGATTTGAAGAAGCACATGGATTCATGTCCTGAATTCTCTAAGGATACCGGTGTTGTAAAATCGTTTGTGTATCAAATGCTCCGTGGTCTTGCTTATTGTCATTCTCGTAGAGTTCTCCACAGAGATCTAAAGCCTCAGAATTTGCTGATAGATCCACGCACCAATGTGTTAAAGCTTGCAGATTTTGGATTGGGTAGAGCATTTGGTATTCCTGTTAGAACTTTTACTCATGAGGTGGTGACATTATGGTACAGGGCACCAGAAATACTGCTTGGATCAAGGCACTACTCTACTCCGGTTGATGTGTGGTCGGCTGGTTGCATATTTGCCGAGATGGTTAACCAGCAGCCCCTTTTTCCTGGTGACTCAGAGATTGATGAACTTTTCAGCATTTTCAGAGTGGTGGGTACTCCAAATGAGAATACATGGCCTGGAGTGACTTCTTTGCCTGATTATAAATCTTCATTTCCAAAATGGAGTCCTAAGGATCTGGCAACTTTAGTCCCGAATCTTGATACTGCAGGATTTGATCTCCTTGGTAAAATGCTCTGCTTGGACCCCAGCAAGAGAATCACTGCCAAAAGTGCCCTTGAACATGAGTATTTCAAGGATATTGGCCGTGTTCGATGA
Protein Sequence
  • >Solyc11g070140.2.1
    MDQYEKIGKIGEGTYGVVYKAFVRETKEIVALKKIRLEQEDEGVPSTAIREISLLKEMQHGNIVRLLDVVHSERRLYLVFEYLDLDLKKHMDSCPEFSKDTGVVKSFVYQMLRGLAYCHSRRVLHRDLKPQNLLIDPRTNVLKLADFGLGRAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDVWSAGCIFAEMVNQQPLFPGDSEIDELFSIFRVVGTPNENTWPGVTSLPDYKSSFPKWSPKDLATLVPNLDTAGFDLLGKMLCLDPSKRITAKSALEHEYFKDIGRVR*