Gene Details:

Functional Descriptions:

  • The tomato (Solanum lycopersicum) LeEIX2 is an RLP that binds ethylene-inducing xylanase (EIX), a fungal elicitor.
  • Co-expression of SlRLK-like with LeEIX2 led to a reduction in its abundance, apparently through an endoplasmic reticulum-associated degradation process.
  • Report the identification of SlRLK-like, which contains a malectin-like domain, as a novel LeEIX2 interactor and show that it acts as a negative regulator of defense responses mediated by the RLP LeEIX2 by significantly reducing its abundance.
  • LeEIX2 protein function, even prior to EIX perception, emphasizing the importance of tightly regulating a signaling pathway able to result in an HR and eventually cell death.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >Solyc07g008630.1.1
    ATGGGCAAAAGAACTAATCCAAGACATTTCCTTGTTACTTGGTCTTTACTGCTCCTAGAGACAGCTTTTGGATTAACTTCAAGAGAAGTTAACAAGACCCTTTGTATAGAAAAGGAGAGAGATGCCCTTCTTGAGTTTAAAAGAGGCCTTAACGACGATTTTGGTCGTTTATCTACCTGGGGTGATGAAGAAGAATGCTGCAATTGGAAGGGTATTGAATGTGACAAAAGAACAGGTCATGTTATTGTTCTTGATCTCCACAGTGAGGTTACTTGTCCAGGCCATGCTTGTTTTGCTCCAATATTGACAGGTAAAGTTAGTCCTTCTCTACTTGAGTTGGAGTATTTGAATTTCTTGGACCTCAGTGTTAATGGATTTGAAAATAGTGAGATACCAAGATTCATAGGCTCCCTTAAGAGACTGGAGTACTTAAACCTTTCATCTTCTGATTTTTCTGGTGAAATTCCAGCACAGTTCCAGAATCTAACTTCTTTGAGGATTCTTGATCTCGGAAACAATAATCTTATAGTAAAGGACCTTGTGTGGCTTTCTCATCTCTCCTCTCTAGAATTCTTGCGCCTTGGTGGTAACGATTTCCAAGCAAGAAACTGGTTTCGAGAGATAACTAAGGTCCCTTCATTGAAAGAATTGGACTTGAGTGTTTGTGGACTCTCTAAATTCGTTCCGTCTCCAGCTGATGTAGCTAATTCATCTTTGATCTCTCTTTCTGTTCTTCATTTATGTTGTAATGAGTTTTCTACTTCATCTGAATATAGCTGGTTATTCAATTTTAGCACAAGCCTAACTAGCATAGACCTTTCTCATAATCAACTCAGTCGTCAAATTGATGATCGCTTTGGGAGCTTGATGTATCTTGAACATCTTAATCTTGCTAATAATTTTGGGGCTGAAGGTGGGGTTCCAAGTTCTTTTGGGAATTTGACACGTCTACATTATCTGGACATGTCTAACACTCAGACATACCAATGGCTTCCTGAGTTGTTTCTCAGGTTATCAGGTAGTAGGAAATCACTTGAGGTTTTGGGATTGAACGACAACTCGTTGTTTGGTTCAATTGTTAATGTCACAAGATTTTCATCCTTGAAGAAATTATACCTGCAGAAGAATATGCTGAATGGTTTTTTCATGGAAAGAGTGGGACAAGTTTCGAGCCTCGAGTATCTAGACTTGTCTGATAACCAAATGAGAGGGCCATTACCAGATTTAGCACTTTTTCCATCATTAAGAGAGTTGCATCTTGGCTCTAATCAATTTCAAGGGAGGATACCACAAGGTATTGGAAAACTTTCACAGCTTAGAATTTTTGACGTCTCGTCCAATAGATTAGAGGGTTTACCAGAAAGTATGGGGCAACTATCAAACCTGGAAAGGTTTGATGCTTCTTATAATGTCCTGAAGGGTACAATCACAGAGTCCCACTTTTCAAACCTCTCCAGTTTAGTAGACTTAGACCTATCCTTCAACTTGTTGTCTTTGAACACGAGATTCGATTGGGTTCCTCCTTTTCAACTACAATTTATAAGGCTTCCATCTTGCAATATGGGACCTTCTTTTCCGAAATGGCTACAAACTCAGAATAACTACACTCTTCTTGATATTTCTCTTGCGAATATATCAGACATGCTACCAAGTTGGTTCTCCAATCTTCCTCCCGAGCTCAAGATTCTGAATCTCTCTAACAACCACATCAGTGGCAGAGTTTCGGAGTTCATAGTGAGTAAACAAGATTACATGATTATAGATTTAAGTTCTAACAACTTTTCAGGACATTTGCCACTAGTTCCTGCCAATATACAGATCTTTTACCTTCATAAAAATCACTTCTCTGGATCCATTTCTTCCATTTGTAGAAATACAATAGGAGCTGCCACTTCCATCGACTTGTCACGCAACCAATTTTCAGGAGAAGTTCCTGATTGTTGGATGAATATGAGTAATCTAGCTGTTCTAAATCTAGCCTACAACAATTTCTCCGGAAAAGTTCCACAATCATTAGGCTCCTTGACAAATTTGGAGGCGTTATACATACGTCAGAACAGCTTTAGAGGAATGTTGCCTTCTTTTTCACAATGTCAGCTGCTGCAAATCTTGGATATTGGAGGGAATAAGTTGACTGGAAGAATCCCAGCATGGATAGGGACTGACCTACTCCAATTGCGCATTCTAAGCCTACGTTCCAACAAATTCGATGGCAGCATTCCATCACTTATCTGCCAGCTTCAATTTCTTCAGATACTGGACCTTTCAGAAAATGGATTATCTGGGAAAATTCCACAGTGCCTCAACAACTTTACCATATTGCGTCAAGAAAATGGCTCTGGTGAGTCAATGGATTTTAAAGTCCGTTATGACTATATTCCAGGATCTTACTTGTACATAGGTGATTTACTGATTCAATGGAAAAACCAGGAGTCCGAGTACAAGAATGCTTTACTATATCTGAAGATCATTGATCTTTCAAGTAATAAATTAGTTGGAGGTATCCCTAAAGAGATAGCTGAAATGAGAGGATTGAGATCATTGAACCTCTCGAGAAATGATCTTAATGGAACTGTCGTTGAAGGAATAGGTCAAATGAAGTTGTTGGAGTCCCTCGACTTGTCAAGAAACCAACTCTCTGGCATGATCCCTCAGGGCCTTTCTAACTTGACTTTTCTTAGTGTGTTGGACTTATCGAACAACCACTTATCAGGAAGAATTCCATCAAGCACTCAACTGCAGAGTTTCGATAGATCATCCTATAGTGGCAATGCTCAACTCTGCGGTCCTCCTCTTGAAGAGTGTCCTGGATATGCTCCCCCTATCGATCGTGGAAGCAACACCAATCCACAAGAACATGATGATGATGATGAGTTCTCATCTCTGGAGTTTTATGTATCAATGGTGCTAGGTTTCTTCGTCACGTTCTGGGGAATTTTAGGCTGTTTGATTGTCAACCGTTCGTGGAGGAATGCCTACTTCACATTCTTAACAGACATGAAGAGTTGGCTCCATATGACATCAAGAGTCTGCTTTGCAAGACTGAAGGGAAAGCTAAGGAACTGA
CDS Sequence
  • >Solyc07g008630.1.1
    ATGGGCAAAAGAACTAATCCAAGACATTTCCTTGTTACTTGGTCTTTACTGCTCCTAGAGACAGCTTTTGGATTAACTTCAAGAGAAGTTAACAAGACCCTTTGTATAGAAAAGGAGAGAGATGCCCTTCTTGAGTTTAAAAGAGGCCTTAACGACGATTTTGGTCGTTTATCTACCTGGGGTGATGAAGAAGAATGCTGCAATTGGAAGGGTATTGAATGTGACAAAAGAACAGGTCATGTTATTGTTCTTGATCTCCACAGTGAGGTTACTTGTCCAGGCCATGCTTGTTTTGCTCCAATATTGACAGGTAAAGTTAGTCCTTCTCTACTTGAGTTGGAGTATTTGAATTTCTTGGACCTCAGTGTTAATGGATTTGAAAATAGTGAGATACCAAGATTCATAGGCTCCCTTAAGAGACTGGAGTACTTAAACCTTTCATCTTCTGATTTTTCTGGTGAAATTCCAGCACAGTTCCAGAATCTAACTTCTTTGAGGATTCTTGATCTCGGAAACAATAATCTTATAGTAAAGGACCTTGTGTGGCTTTCTCATCTCTCCTCTCTAGAATTCTTGCGCCTTGGTGGTAACGATTTCCAAGCAAGAAACTGGTTTCGAGAGATAACTAAGGTCCCTTCATTGAAAGAATTGGACTTGAGTGTTTGTGGACTCTCTAAATTCGTTCCGTCTCCAGCTGATGTAGCTAATTCATCTTTGATCTCTCTTTCTGTTCTTCATTTATGTTGTAATGAGTTTTCTACTTCATCTGAATATAGCTGGTTATTCAATTTTAGCACAAGCCTAACTAGCATAGACCTTTCTCATAATCAACTCAGTCGTCAAATTGATGATCGCTTTGGGAGCTTGATGTATCTTGAACATCTTAATCTTGCTAATAATTTTGGGGCTGAAGGTGGGGTTCCAAGTTCTTTTGGGAATTTGACACGTCTACATTATCTGGACATGTCTAACACTCAGACATACCAATGGCTTCCTGAGTTGTTTCTCAGGTTATCAGGTAGTAGGAAATCACTTGAGGTTTTGGGATTGAACGACAACTCGTTGTTTGGTTCAATTGTTAATGTCACAAGATTTTCATCCTTGAAGAAATTATACCTGCAGAAGAATATGCTGAATGGTTTTTTCATGGAAAGAGTGGGACAAGTTTCGAGCCTCGAGTATCTAGACTTGTCTGATAACCAAATGAGAGGGCCATTACCAGATTTAGCACTTTTTCCATCATTAAGAGAGTTGCATCTTGGCTCTAATCAATTTCAAGGGAGGATACCACAAGGTATTGGAAAACTTTCACAGCTTAGAATTTTTGACGTCTCGTCCAATAGATTAGAGGGTTTACCAGAAAGTATGGGGCAACTATCAAACCTGGAAAGGTTTGATGCTTCTTATAATGTCCTGAAGGGTACAATCACAGAGTCCCACTTTTCAAACCTCTCCAGTTTAGTAGACTTAGACCTATCCTTCAACTTGTTGTCTTTGAACACGAGATTCGATTGGGTTCCTCCTTTTCAACTACAATTTATAAGGCTTCCATCTTGCAATATGGGACCTTCTTTTCCGAAATGGCTACAAACTCAGAATAACTACACTCTTCTTGATATTTCTCTTGCGAATATATCAGACATGCTACCAAGTTGGTTCTCCAATCTTCCTCCCGAGCTCAAGATTCTGAATCTCTCTAACAACCACATCAGTGGCAGAGTTTCGGAGTTCATAGTGAGTAAACAAGATTACATGATTATAGATTTAAGTTCTAACAACTTTTCAGGACATTTGCCACTAGTTCCTGCCAATATACAGATCTTTTACCTTCATAAAAATCACTTCTCTGGATCCATTTCTTCCATTTGTAGAAATACAATAGGAGCTGCCACTTCCATCGACTTGTCACGCAACCAATTTTCAGGAGAAGTTCCTGATTGTTGGATGAATATGAGTAATCTAGCTGTTCTAAATCTAGCCTACAACAATTTCTCCGGAAAAGTTCCACAATCATTAGGCTCCTTGACAAATTTGGAGGCGTTATACATACGTCAGAACAGCTTTAGAGGAATGTTGCCTTCTTTTTCACAATGTCAGCTGCTGCAAATCTTGGATATTGGAGGGAATAAGTTGACTGGAAGAATCCCAGCATGGATAGGGACTGACCTACTCCAATTGCGCATTCTAAGCCTACGTTCCAACAAATTCGATGGCAGCATTCCATCACTTATCTGCCAGCTTCAATTTCTTCAGATACTGGACCTTTCAGAAAATGGATTATCTGGGAAAATTCCACAGTGCCTCAACAACTTTACCATATTGCGTCAAGAAAATGGCTCTGGTGAGTCAATGGATTTTAAAGTCCGTTATGACTATATTCCAGGATCTTACTTGTACATAGGTGATTTACTGATTCAATGGAAAAACCAGGAGTCCGAGTACAAGAATGCTTTACTATATCTGAAGATCATTGATCTTTCAAGTAATAAATTAGTTGGAGGTATCCCTAAAGAGATAGCTGAAATGAGAGGATTGAGATCATTGAACCTCTCGAGAAATGATCTTAATGGAACTGTCGTTGAAGGAATAGGTCAAATGAAGTTGTTGGAGTCCCTCGACTTGTCAAGAAACCAACTCTCTGGCATGATCCCTCAGGGCCTTTCTAACTTGACTTTTCTTAGTGTGTTGGACTTATCGAACAACCACTTATCAGGAAGAATTCCATCAAGCACTCAACTGCAGAGTTTCGATAGATCATCCTATAGTGGCAATGCTCAACTCTGCGGTCCTCCTCTTGAAGAGTGTCCTGGATATGCTCCCCCTATCGATCGTGGAAGCAACACCAATCCACAAGAACATGATGATGATGATGAGTTCTCATCTCTGGAGTTTTATGTATCAATGGTGCTAGGTTTCTTCGTCACGTTCTGGGGAATTTTAGGCTGTTTGATTGTCAACCGTTCGTGGAGGAATGCCTACTTCACATTCTTAACAGACATGAAGAGTTGGCTCCATATGACATCAAGAGTCTGCTTTGCAAGACTGAAGGGAAAGCTAAGGAACTGA
Protein Sequence
  • >Solyc07g008630.1.1
    MGKRTNPRHFLVTWSLLLLETAFGLTSREVNKTLCIEKERDALLEFKRGLNDDFGRLSTWGDEEECCNWKGIECDKRTGHVIVLDLHSEVTCPGHACFAPILTGKVSPSLLELEYLNFLDLSVNGFENSEIPRFIGSLKRLEYLNLSSSDFSGEIPAQFQNLTSLRILDLGNNNLIVKDLVWLSHLSSLEFLRLGGNDFQARNWFREITKVPSLKELDLSVCGLSKFVPSPADVANSSLISLSVLHLCCNEFSTSSEYSWLFNFSTSLTSIDLSHNQLSRQIDDRFGSLMYLEHLNLANNFGAEGGVPSSFGNLTRLHYLDMSNTQTYQWLPELFLRLSGSRKSLEVLGLNDNSLFGSIVNVTRFSSLKKLYLQKNMLNGFFMERVGQVSSLEYLDLSDNQMRGPLPDLALFPSLRELHLGSNQFQGRIPQGIGKLSQLRIFDVSSNRLEGLPESMGQLSNLERFDASYNVLKGTITESHFSNLSSLVDLDLSFNLLSLNTRFDWVPPFQLQFIRLPSCNMGPSFPKWLQTQNNYTLLDISLANISDMLPSWFSNLPPELKILNLSNNHISGRVSEFIVSKQDYMIIDLSSNNFSGHLPLVPANIQIFYLHKNHFSGSISSICRNTIGAATSIDLSRNQFSGEVPDCWMNMSNLAVLNLAYNNFSGKVPQSLGSLTNLEALYIRQNSFRGMLPSFSQCQLLQILDIGGNKLTGRIPAWIGTDLLQLRILSLRSNKFDGSIPSLICQLQFLQILDLSENGLSGKIPQCLNNFTILRQENGSGESMDFKVRYDYIPGSYLYIGDLLIQWKNQESEYKNALLYLKIIDLSSNKLVGGIPKEIAEMRGLRSLNLSRNDLNGTVVEGIGQMKLLESLDLSRNQLSGMIPQGLSNLTFLSVLDLSNNHLSGRIPSSTQLQSFDRSSYSGNAQLCGPPLEECPGYAPPIDRGSNTNPQEHDDDDEFSSLEFYVSMVLGFFVTFWGILGCLIVNRSWRNAYFTFLTDMKSWLHMTSRVCFARLKGKLRN*