Gene Details:

Functional Descriptions:

  • AGO2a but not AGO2b mediates antiviral defense against infection of wild-type cucumber mosaic virus in tomato.
  • AGO2a nor AGO2b regulated disease induction after infection with either virus. Our findings firstly reveal a prominent role of AGO2a in antiviral RNAi innate immunity in tomato and demonstrate that antiviral RNAi evolves to defend against infection of natural wild-type CMV-Fny in tomato.
  • AGO2b should be a pseudogene without function due to the diminished expression level of AGO2b in tomato.
  • We found that AGO2a but not AGO2b was significantly induced to inhibit the propagation of not only VSR-deficient Cucumber mosaic virus (CMV) but also wild-type CMV-Fny in tomato| however, neither AGO2a nor AGO2b regulated disease induction after infection with either virus.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Orthologs:

Sequences:

cDNA Sequence
  • >Solyc02g069270.2.1
    ATGGACCGTGGAAACTACCAACGTGGTGGCGGCGACAACACCGGCAGGGGCAGAGGTAACCGTGGTCGGGGTGGAAGGGGTGGGACCCATGTCGGTGGTGGAAGGGGTGGGCCCCAAATGGGTTCATTTCATCAGCCTCCACAGCAATGGGGGAATCAGCCAAGGGGGTCGGGTCAATATCAGTTTCGTGGAGCTCCGCCGGGTCGTGGTGGTACTTGGGTCAACCAACCGGTCCAACGTGGTGGTGGTAACGCTTGGCAACGGCCACAACAGCAGGGTAGTGGTGTTCCAATCACTGCTTGGGCCCGACCACCACCGCAGCAGCCACAGCAACAGGGTAGTGGTGGTGGAGTTGCTACTGCTTGGGCCCGGCCGCCGCCGCCGCCACAGGAGGTTGTGGATCGTCCTCAATCTTCTGATCCTGTTCATGTTGATATGGGGTCCCTGAAAATTACAGAAGCGAGTTCATCAGAAAGTTCTAAGGAAAAACGTGTACCAGTCGCACGACCTGATACTGGAAAAAATTGTGTAAAGCAAATTGAGCTGCTGGCTAATCATTTTGTTGTTGCATTTGATCCCCACTCTACCATTATGCATTATGATGTGAATATTCAACAACAGCAAAGCTGTGCGAGGGATAACCCTATTCGATTTCCCCTAGATAATACTGCATATGACGGTAACAAGAACATTTTCAGTGCTGTTCAACTTCCTACTGGGTGTTTTGCTGTGAACTGGTCTGACGGGGAAGATTTTAAGTCACGCACTTATGACATTACCATCAACCTTGTTGCTGAATTACAACTTAGGAAGCTGGAACAATATTTGAGTGGAAACCTTTCGTATACTCCTCGTGATATACTGCAAGGAATGGATTTGTTTATGAAAGATAATCCTTCTAGACACAGGATTTCTGTAGGTCGTTGTTTCTACTCTAAGAATCCTCATAAAGACTTTAGATTCGGGGCTGCTGCATATAAAGGTTTTCAGCAGAGCTTAAAGCCTACAGAAGCAGGGTTGGCGTTGTGCTTAGATTACTCAGTTTTGGCACTCCGGAAACCAATGTCAGTGCTAAACTATCTGAGGAACTATTTTCAAATACCTAAAGAAGATATTTTCAGGTACAACCATCAAGCTGCACATGATGCATTAAAGGGTTTGAAAGTCACAGTAAATCATCGTCGTACAAGCCAGAAGTTTGTTATTAAGAAGCTAACGGATCGCAAAACTAGTGAAATTACTTTCCCCCTTGAAGATCCAGAAGGCAAAGATCCCCCAAGGGATGTTCTTCTTGTTGAATACTTCAGGGATAAATATCAGCGGGAGATTCAGTTCAAGGATTTTCCTTCATTAGATGTTGGAAAAGGTAGTAAGATAAACTATGTCCCAATGGAATTCTGTGTCTTGGTTGAGGGACAACGGTTTCCTAAGGAGGAGTTGGACAAGGCATCTGCTATGTTTTTGAAGAACATGTCATTAGCTCAACCCAACGAGAGAAAGGAGGCAACTTGTGAAATGGTAAAGGCTGAAGATGGGCCGTGCGGGGCTATCACCGATAATTTTGGGATCAAAGTTGATAAGAACATGACCGGTGTTGTCGGTCGTGTTCTTCCTCCCCCTGATTTGAAGCTAGGCGGTCAAAGTCCACTTCGTGTGAATGATAAGTGCCAGTGGAACCTTGTTGGGAAATCTGTGGTGGAAGGCAAGGCACTTCAACGATGGGCTTTGATAGATTTTAGCTCTAAGGAACGCAACTGGCTAAGAGTTGACGAGTTTGTCATCGGATTGAGAGATCGGTGCAGCAAATTGAGTATTAATATGGAAGGACCTGCTGAAGTACATTTGACTGACATGCATGAACTCTCTGAAGTTGGCAAGGTTGAAAAACTTCTCAATTTTGTGGTTGATGCAGCTAAACGGAAAATCAATGGTAAACTTCAAATGATAGTTTGTGTTATGACATCAAAGCATAATGGGTACAAATATCTTAAATGGGTATCTGAGACAAAAATCGGCGTGGTAACCCAGTGTTGCTTGTCTACTAATGCCAACAAGGGACAGGATCAGTATCTTGCAAACCTCTGTATGAAGATTAATGCAAAACTTGGGGGCAGCAATATGGAACTTATGCAAAGACTCCCTAATTTTAGAAATGGAGACAATGTCATGTTCATCGGAGCTGATGTTAATCATCCTACTTCCCGGGATGCTGACAAATATCCATCCATAGCAGCCGTTGTTGCCACCATTAACTGGCCAGCTGCTAATAGATATGCTGCTAGAGTTTGTCCTCAGAAACACAGGACTGAGAAGATTCTAGAGTTTGGAAAGATGTGTGCAGACCTAGTTCGTACTTATGAGGAACTCAACTCTGTTAAACCAAACAAAATTGTTGTTTTCCGTGATGGTGTGAGTGGGAGTCAATTTGATATGGTACTCAACGAAGAGTTGAATGATTTGGTAAAAGATATATACGATCGTTACAAGTATAAACCTGAAATCACTCTTGTTGTGGCTCAGAAAAGACACCATACGCGACTATTTCCTAGGGAGGGAAATGTGCCTCCAGGTACTGTTGTGGATACGCAAATTGTTCATCCATTTGATTTTGACTTCTATCTTTGCAGCCACTTTGGACAGTTGGGTACTAGCAAGGCAACTCACTATCATGTTCTATGGGATGAGAATGGTTTCAATTCTGACATCTTACAACGTCTTATATACAACATGTGCTTCACTTTTGCGCGATGCACTAAACCTGTCTCACTTGTTCCACCAGTTTACTACGCAGACCTTGTTGCTTACAGGGGACGGATGTTCCAGGAGGTGGTTATGGAGATGAACGCTTCTAGCTCTACAACTTCACCTGCCTCATTTGAACAAAGATTTTATAATTTGCAGCCTGATTTGCAGAACATTATGTTTTTTGTCTGATGGCACACTTTTTTTACCACACTGGGGAAGAGATGATTGTCTACATTTTGGAGAGTTTCTAATGGGATTTCATGCTTCTTTTATTCTCTATGCATTGATGTCTTAATGGTTTGATTATGTTTTAATAATTTTACTTTTACATGTCCCGTATTATGTATTCCCAGTCAAGTTGTTAATAAATTTGTGTTCATGTCTCT
CDS Sequence
  • >Solyc02g069270.2.1
    ATGGACCGTGGAAACTACCAACGTGGTGGCGGCGACAACACCGGCAGGGGCAGAGGTAACCGTGGTCGGGGTGGAAGGGGTGGGACCCATGTCGGTGGTGGAAGGGGTGGGCCCCAAATGGGTTCATTTCATCAGCCTCCACAGCAATGGGGGAATCAGCCAAGGGGGTCGGGTCAATATCAGTTTCGTGGAGCTCCGCCGGGTCGTGGTGGTACTTGGGTCAACCAACCGGTCCAACGTGGTGGTGGTAACGCTTGGCAACGGCCACAACAGCAGGGTAGTGGTGTTCCAATCACTGCTTGGGCCCGACCACCACCGCAGCAGCCACAGCAACAGGGTAGTGGTGGTGGAGTTGCTACTGCTTGGGCCCGGCCGCCGCCGCCGCCACAGGAGGTTGTGGATCGTCCTCAATCTTCTGATCCTGTTCATGTTGATATGGGGTCCCTGAAAATTACAGAAGCGAGTTCATCAGAAAGTTCTAAGGAAAAACGTGTACCAGTCGCACGACCTGATACTGGAAAAAATTGTGTAAAGCAAATTGAGCTGCTGGCTAATCATTTTGTTGTTGCATTTGATCCCCACTCTACCATTATGCATTATGATGTGAATATTCAACAACAGCAAAGCTGTGCGAGGGATAACCCTATTCGATTTCCCCTAGATAATACTGCATATGACGGTAACAAGAACATTTTCAGTGCTGTTCAACTTCCTACTGGGTGTTTTGCTGTGAACTGGTCTGACGGGGAAGATTTTAAGTCACGCACTTATGACATTACCATCAACCTTGTTGCTGAATTACAACTTAGGAAGCTGGAACAATATTTGAGTGGAAACCTTTCGTATACTCCTCGTGATATACTGCAAGGAATGGATTTGTTTATGAAAGATAATCCTTCTAGACACAGGATTTCTGTAGGTCGTTGTTTCTACTCTAAGAATCCTCATAAAGACTTTAGATTCGGGGCTGCTGCATATAAAGGTTTTCAGCAGAGCTTAAAGCCTACAGAAGCAGGGTTGGCGTTGTGCTTAGATTACTCAGTTTTGGCACTCCGGAAACCAATGTCAGTGCTAAACTATCTGAGGAACTATTTTCAAATACCTAAAGAAGATATTTTCAGGTACAACCATCAAGCTGCACATGATGCATTAAAGGGTTTGAAAGTCACAGTAAATCATCGTCGTACAAGCCAGAAGTTTGTTATTAAGAAGCTAACGGATCGCAAAACTAGTGAAATTACTTTCCCCCTTGAAGATCCAGAAGGCAAAGATCCCCCAAGGGATGTTCTTCTTGTTGAATACTTCAGGGATAAATATCAGCGGGAGATTCAGTTCAAGGATTTTCCTTCATTAGATGTTGGAAAAGGTAGTAAGATAAACTATGTCCCAATGGAATTCTGTGTCTTGGTTGAGGGACAACGGTTTCCTAAGGAGGAGTTGGACAAGGCATCTGCTATGTTTTTGAAGAACATGTCATTAGCTCAACCCAACGAGAGAAAGGAGGCAACTTGTGAAATGGTAAAGGCTGAAGATGGGCCGTGCGGGGCTATCACCGATAATTTTGGGATCAAAGTTGATAAGAACATGACCGGTGTTGTCGGTCGTGTTCTTCCTCCCCCTGATTTGAAGCTAGGCGGTCAAAGTCCACTTCGTGTGAATGATAAGTGCCAGTGGAACCTTGTTGGGAAATCTGTGGTGGAAGGCAAGGCACTTCAACGATGGGCTTTGATAGATTTTAGCTCTAAGGAACGCAACTGGCTAAGAGTTGACGAGTTTGTCATCGGATTGAGAGATCGGTGCAGCAAATTGAGTATTAATATGGAAGGACCTGCTGAAGTACATTTGACTGACATGCATGAACTCTCTGAAGTTGGCAAGGTTGAAAAACTTCTCAATTTTGTGGTTGATGCAGCTAAACGGAAAATCAATGGTAAACTTCAAATGATAGTTTGTGTTATGACATCAAAGCATAATGGGTACAAATATCTTAAATGGGTATCTGAGACAAAAATCGGCGTGGTAACCCAGTGTTGCTTGTCTACTAATGCCAACAAGGGACAGGATCAGTATCTTGCAAACCTCTGTATGAAGATTAATGCAAAACTTGGGGGCAGCAATATGGAACTTATGCAAAGACTCCCTAATTTTAGAAATGGAGACAATGTCATGTTCATCGGAGCTGATGTTAATCATCCTACTTCCCGGGATGCTGACAAATATCCATCCATAGCAGCCGTTGTTGCCACCATTAACTGGCCAGCTGCTAATAGATATGCTGCTAGAGTTTGTCCTCAGAAACACAGGACTGAGAAGATTCTAGAGTTTGGAAAGATGTGTGCAGACCTAGTTCGTACTTATGAGGAACTCAACTCTGTTAAACCAAACAAAATTGTTGTTTTCCGTGATGGTGTGAGTGGGAGTCAATTTGATATGGTACTCAACGAAGAGTTGAATGATTTGGTAAAAGATATATACGATCGTTACAAGTATAAACCTGAAATCACTCTTGTTGTGGCTCAGAAAAGACACCATACGCGACTATTTCCTAGGGAGGGAAATGTGCCTCCAGGTACTGTTGTGGATACGCAAATTGTTCATCCATTTGATTTTGACTTCTATCTTTGCAGCCACTTTGGACAGTTGGGTACTAGCAAGGCAACTCACTATCATGTTCTATGGGATGAGAATGGTTTCAATTCTGACATCTTACAACGTCTTATATACAACATGTGCTTCACTTTTGCGCGATGCACTAAACCTGTCTCACTTGTTCCACCAGTTTACTACGCAGACCTTGTTGCTTACAGGGGACGGATGTTCCAGGAGGTGGTTATGGAGATGAACGCTTCTAGCTCTACAACTTCACCTGCCTCATTTGAACAAAGATTTTATAATTTGCAGCCTGATTTGCAGAACATTATGTTTTTTGTCTGA
Protein Sequence
  • >Solyc02g069270.2.1
    MDRGNYQRGGGDNTGRGRGNRGRGGRGGTHVGGGRGGPQMGSFHQPPQQWGNQPRGSGQYQFRGAPPGRGGTWVNQPVQRGGGNAWQRPQQQGSGVPITAWARPPPQQPQQQGSGGGVATAWARPPPPPQEVVDRPQSSDPVHVDMGSLKITEASSSESSKEKRVPVARPDTGKNCVKQIELLANHFVVAFDPHSTIMHYDVNIQQQQSCARDNPIRFPLDNTAYDGNKNIFSAVQLPTGCFAVNWSDGEDFKSRTYDITINLVAELQLRKLEQYLSGNLSYTPRDILQGMDLFMKDNPSRHRISVGRCFYSKNPHKDFRFGAAAYKGFQQSLKPTEAGLALCLDYSVLALRKPMSVLNYLRNYFQIPKEDIFRYNHQAAHDALKGLKVTVNHRRTSQKFVIKKLTDRKTSEITFPLEDPEGKDPPRDVLLVEYFRDKYQREIQFKDFPSLDVGKGSKINYVPMEFCVLVEGQRFPKEELDKASAMFLKNMSLAQPNERKEATCEMVKAEDGPCGAITDNFGIKVDKNMTGVVGRVLPPPDLKLGGQSPLRVNDKCQWNLVGKSVVEGKALQRWALIDFSSKERNWLRVDEFVIGLRDRCSKLSINMEGPAEVHLTDMHELSEVGKVEKLLNFVVDAAKRKINGKLQMIVCVMTSKHNGYKYLKWVSETKIGVVTQCCLSTNANKGQDQYLANLCMKINAKLGGSNMELMQRLPNFRNGDNVMFIGADVNHPTSRDADKYPSIAAVVATINWPAANRYAARVCPQKHRTEKILEFGKMCADLVRTYEELNSVKPNKIVVFRDGVSGSQFDMVLNEELNDLVKDIYDRYKYKPEITLVVAQKRHHTRLFPREGNVPPGTVVDTQIVHPFDFDFYLCSHFGQLGTSKATHYHVLWDENGFNSDILQRLIYNMCFTFARCTKPVSLVPPVYYADLVAYRGRMFQEVVMEMNASSSTTSPASFEQRFYNLQPDLQNIMFFV*