Information report for SlTPL3
Gene Details
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Functional Descriptions
- The SlTPL3–SlWUS module regulates SAM size by mediating auxin distribution and GA levels, and perturbations of this module result in enlarged SAM. These results provide novel insights into the molecular mechanism of SAM maintenance and locule formation in tomato and highlight the SlTPL3–SlWUS module as a key regulator.
- Recent studies have demonstrated that a mutation in CLAVATA3 (SlCLV3), caused by a 294-kb inversion with breakpoints in intron 1 of YABBY and 1 kb upstream of SlCLV3, in fact underlies the fas mutant phenotype.
- The expression pattern of TOPLESS3 (SlTPL3) throughout SAM development prompted us to investigate its functional significance via RNA interference (RNAi) and clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease 9 (Cas9)-mediated gene editing.
- SlTPL3 interacted with WUSCHEL (SlWUS), which plays an important role in SAM size maintenance.
Functional Keywords
- development , auxin , ga , sam
Literature and News
Gene Resources
- NCBI ID: 101262960
- UniProt accessions: A0A3Q7F8F1
- AlphaFoldDB: A0A3Q7F8F1
- EnsemblPlants: Solyc01g100050.3.1
- Gramene: Solyc01g100050.3.1
- GO: GO:0005886 , GO:0006355 , GO:0010072 , GO:0062208 , GO:0140311
- OMA: CLWSIDS
- InterPro: IPR001680 , IPR006594 , IPR006595 , IPR011047 , IPR015943 , IPR019775 , IPR027728 , IPR036322 , IPR048419 , IPR054080 , IPR054532
- PANTHER: PTHR44083 , PTHR44083:SF2
- SUPFAM: SSF50978 , SSF50998
- PROSITE: PS00678 , PS50082 , PS50294 , PS50896 , PS50897
- Gene3D: 2.130.10.10
- OrthoDB: A0A3Q7F8F1
- Pfam: PF00400 , PF17814 , PF21359 , PF21889
- STRING: 4081.A0A3Q7F8F1
Sequences
cDNA Sequence
- >Solyc01g100050.3.1
TTTCTCTCTCTATATACCTATTCTTTCTCTCTCTAAATATATATATATATATATAATTTCTCTTTCTTCTTCGGCAGCCTTTGGAAATCAAGCACTGATTTATTAATTGTTTATGTGAGAGAGGAGGAGCTGAAACCCTAGAAATCGTAGCGCGTGTGGATATCTAGGGCTTGGATCTGTGGAGTTCTGGAATCGGAGATTGTTGGATTTGGGGGTTTTGAAGAGAGTTGGAAAAAATGTCTTCTCTTAGCAGAGAATTGGTGTTCCTCATACTTCAGTTTCTAGAAGAGGAGAAATTTAAGGAGTCCGTTCACAAGCTCGAGCAAGAATCAGGATTTTTCTTCAATATGAAGTACTTTGAGGAGAAAGTACATGCAGGTGAGTGGGACGAAGTTGAGAAGTACTTGTCCGGATTTACCAAAGTTGACGACAACAGATATTCAATGAAAATCTTTTTTGAGATTAGAAAGCAGAAATATCTTGAAGCTCTTGATAAGCAAGACAAGGCAAAGGCAGTTGAGATTCTTGTGAGTGATTTGAAAGTGTTCTCTACATTCAATGAGGACCTTTACAAAGAGATCACTCAACTCTTGACGCTTACCAATTTCAGAGAGAACGAGCAGCTTTCGAAGTATGGTGACACCAAGACAGCGCGTAGCATAATGTTGATAGAGCTGAAGAAGTTGATTGAAGCAAATCCTCTTTTCCGTGAAAAGCTCGTCTTCCCGACTCTGAGATCTTCAAGATTGCGTACATTAATCAATCAAAGTCTCAACTGGCAGCACCAGCTTTGCAAGAACCCAAGGCCAAACCCTGACATTAAGACTCTGTTCACAGATCATACATGCACTCCTCCAAATGGGGCTGTTGCACCTACACCCGTTAATCTTCCTCCTGCAGCGATTGCAAAACCTGCCGCTTTTACAGCACTTGGTGCACATGGGCCCTTTCCACCTGCAGCAGCAGCTGCTGCAAATGCTAATGCTTTAGCAGGTTGGATGGCAAACGCCGCTGCTTCTTCATCTGTCCAAGCTGCTGTTGTGACAGCATCATCCCTGCCTGTTCCACCAAATCAAGTTTCAATTTTGAAGCGCCCCCTCACACCTCCAGCTACATTAGGCATGCTTGACTATCAGAGTGCTGATCATGAGCAATTAATGAAACGTTTACGACCTGCACAGTCTGTTGAGGAGGTTACGTATCCTACAGTTCGTCAGCAAGCTTCTTGGTCCCTTGATGACTTACCAAGGACCGTAGCTTTTACTTTACCTCAAGGATCCTCAGTCACTAGCATGGACTTTCATCCTTCTCATCATACATATCTGCTCGTTGGATCCACCAATGGTGAAATAACGCTCTGGGAAGTAGCAACACGAGAGAAGTTGGTTGCGAAGGCATTTAAAATATGGGATGTTCAAGCGTGTACTCTGACATTTCAGGCTTCTGCTTCCAAAGATGCACCATTTTCTGTAAGCCGTGTTGCCTGGAGTCCAGATGGGACCTTCGTTGGAGTTGCATTCTCTAAGCATTTGGTCCATCTGTATGCCACTGTTGGAACAAATGATTTGCGCCAGCATTTGGAGATGGATGCCCATGCTGGAAGTGTTAACGACTTAGCATTTGCTTATCCAAACAAGCAGTTATGTATAGTAACATGTGGAGATGATAAGTTGATAAAGGTGTGGGATATAACAGGAAGAAAGCTGTTTAATTTTGAAGGACATGAAGCTCCTGTATATTCCATATGCCCTCATCAGAAGGAGAGCATTCAGTTCATTTTTTCTACTGCTATAGATGGAAAAATAAAAGCTTGGCTGTATGACAATATGGGATCTCGAGTTGACTATGATGCTCCTGGTCATTGGTGTACCACCATGCTTTATAGTGCTGATGGAACTAGATTGTTCTCTTGTGGAACCGGTAAAGAAGGTGATTCTTTTCTTGTGGAATGGAATGAAAGTGAAGGAGCCATAAAGAGGACTTATTCTGGGTTTAGAAAGAAATCAGCTGGTGTTGTGCAGTTTGACACAACTCAAAATCACTTCTTGGCTGTGGGTGAAGATAGCCAGATAAAATTTTGGGACATGGACAATATAAATATTCTTACAACTATAGATGCTGATGGTGGTCTCCCGAGTCTTCCACGCTTGAGATTCAATAAGGAGGGGAATCTTCTTGCTGTTACTACTGCTGACAATGGGATTAAGATACTGGGAAACCCTGCTGGTATGAGATCCTTGAGAACAGTTGAGGCCCCACCTTTTGAAGCACTAAGATCACCCATTGAAGCAGCTGCTATAAAGCAGGGTTCTGGCTCTTCTGTTCCAAATGCTACTCCTGTCAATTGTAAAGTTGAAAGGAGCTCTCCTATCAGGCCGTCTCCTATCCTTAATGGAGTTGATTCTGTGCCCAGAAGCATGGAGAAACCAAGAATATTGGAGGAAGTTTCAGATAAGGCCAAACCCTGGCAGTTAACGGAAATTTTAGACCAAGCTCAATGCAGGCTGGTTACCATGCCTGAGAGTTCAGATTCGAATAATAAGGTTGCAAGGCTTCTTTATACAAATTCTGGTGTTGGTATTCTGGCACTTGGTTCGAATGGTACTCAAAAGTTGTGGAAGTGGACACGCAATGAACAAAATCCAAGTGGCAAGGCCACTGCTAATGTTGTTCCACAATATTGGCAACCGAACAGTGGTCTTCTTATGACCAACGATATTGTAGGTATCAATTTGGAAGAGGCTGTTCCTTGTATAGCTCTCTCAAAGAATGACTCTTATGTAATGTCAGCTGCTGGTGGGAAAGTGTCACTGTTCAATATGATGACGTTTAAGGTAATGACAACATTTATGCCACCTCCGCCGGCTTCAACTTTCTTAGCATTCCATCCTCAAGATAACAATATTATTGCCATTGGCATGGAGGACTCAACGATCCACATTTATAATGTTAGGGTTGATGAGGTAAAATCCAAGTTAAAAGGCCATCAGAAGCGCATTACTGGTCTTGCTTTCTCCACCAACCTCAACATATTGGTTTCATCAGGTGCTGATGCTCAGCTCTGTTTATGGAGCATTGATTCATGGGACAAGAGGAAATCAGTTCCCATTCAGCTGCCTGCTGGTAAAGCACCTAGTGGTGACACTCGAGTACAGTTCCATGCGGACCAAGTCCGCTTGCTAGTATCCCATGAAACACAGTTAGCAATTTATGATGCATCAAAGATGGAAAGAATTCGCCAGTGGGTCCCCCAAGATGCACTTTCTGCTCCAATAACCTATGCGGCTTACTCTTGCAACAGTCAACTAGTTTATGCTTCCTTTTCTGATGGCAACATCGGGGTATTTGATGCCGATACTCTAAGACTTAGATGTCGTGTTGCTCCCTCAGCTTATTTGTCGCAGGCAGTGTTGACTGGGAGTCAATCTGTGTATCCGTTAGTAGTTGCAGCACATCCACAAGAACCCAGCCAATTTGCAGTTGGGTTGACAGATGGAACTGTTAAAGTGATTGAACCACTGGAATCTGAAGGGAAGTGGGGCGTAAGTCCACCTGTTGATAATGGGATGTTAAATGGCAGGGTGGCCTCCTCTTCGACGGCTAACAACCATGCTGCTGACCAAGTTCAAAGATGAAACCTACTGTATTCTGTCAGTGACATTCTTTTTGTGTATCTTATCAGTATAGGTTTTAGTCCACATCTCTTTATGATGGCACACCTCTTACTCTTTTAGAGAGATTCCTAAACTTTGTTCTATGTTTTTTTCTTCATTTTTATCATTTTTTCTCCATAGTTAAAATAGTAGGGGATGTTCTCCGTTCGGCCATTGGCTTTTGGTTGAAGGTGAATGTCACAGGAAATAGCTCAGTTTAAAGGATCAGTTAATGAATGTCAATACTCTACACACTCTCTCTCTCGGCAGTTCAGTTTTTCTTTTTTAATGATATAATGCTTGTCCTGTATTTGTCTAGCATCGCATTGTAGATTGTGATTTTATACTAATAGCTTTTGTAACAAGGTTTCT
CDS Sequence
- >Solyc01g100050.3.1
ATGTCTTCTCTTAGCAGAGAATTGGTGTTCCTCATACTTCAGTTTCTAGAAGAGGAGAAATTTAAGGAGTCCGTTCACAAGCTCGAGCAAGAATCAGGATTTTTCTTCAATATGAAGTACTTTGAGGAGAAAGTACATGCAGGTGAGTGGGACGAAGTTGAGAAGTACTTGTCCGGATTTACCAAAGTTGACGACAACAGATATTCAATGAAAATCTTTTTTGAGATTAGAAAGCAGAAATATCTTGAAGCTCTTGATAAGCAAGACAAGGCAAAGGCAGTTGAGATTCTTGTGAGTGATTTGAAAGTGTTCTCTACATTCAATGAGGACCTTTACAAAGAGATCACTCAACTCTTGACGCTTACCAATTTCAGAGAGAACGAGCAGCTTTCGAAGTATGGTGACACCAAGACAGCGCGTAGCATAATGTTGATAGAGCTGAAGAAGTTGATTGAAGCAAATCCTCTTTTCCGTGAAAAGCTCGTCTTCCCGACTCTGAGATCTTCAAGATTGCGTACATTAATCAATCAAAGTCTCAACTGGCAGCACCAGCTTTGCAAGAACCCAAGGCCAAACCCTGACATTAAGACTCTGTTCACAGATCATACATGCACTCCTCCAAATGGGGCTGTTGCACCTACACCCGTTAATCTTCCTCCTGCAGCGATTGCAAAACCTGCCGCTTTTACAGCACTTGGTGCACATGGGCCCTTTCCACCTGCAGCAGCAGCTGCTGCAAATGCTAATGCTTTAGCAGGTTGGATGGCAAACGCCGCTGCTTCTTCATCTGTCCAAGCTGCTGTTGTGACAGCATCATCCCTGCCTGTTCCACCAAATCAAGTTTCAATTTTGAAGCGCCCCCTCACACCTCCAGCTACATTAGGCATGCTTGACTATCAGAGTGCTGATCATGAGCAATTAATGAAACGTTTACGACCTGCACAGTCTGTTGAGGAGGTTACGTATCCTACAGTTCGTCAGCAAGCTTCTTGGTCCCTTGATGACTTACCAAGGACCGTAGCTTTTACTTTACCTCAAGGATCCTCAGTCACTAGCATGGACTTTCATCCTTCTCATCATACATATCTGCTCGTTGGATCCACCAATGGTGAAATAACGCTCTGGGAAGTAGCAACACGAGAGAAGTTGGTTGCGAAGGCATTTAAAATATGGGATGTTCAAGCGTGTACTCTGACATTTCAGGCTTCTGCTTCCAAAGATGCACCATTTTCTGTAAGCCGTGTTGCCTGGAGTCCAGATGGGACCTTCGTTGGAGTTGCATTCTCTAAGCATTTGGTCCATCTGTATGCCACTGTTGGAACAAATGATTTGCGCCAGCATTTGGAGATGGATGCCCATGCTGGAAGTGTTAACGACTTAGCATTTGCTTATCCAAACAAGCAGTTATGTATAGTAACATGTGGAGATGATAAGTTGATAAAGGTGTGGGATATAACAGGAAGAAAGCTGTTTAATTTTGAAGGACATGAAGCTCCTGTATATTCCATATGCCCTCATCAGAAGGAGAGCATTCAGTTCATTTTTTCTACTGCTATAGATGGAAAAATAAAAGCTTGGCTGTATGACAATATGGGATCTCGAGTTGACTATGATGCTCCTGGTCATTGGTGTACCACCATGCTTTATAGTGCTGATGGAACTAGATTGTTCTCTTGTGGAACCGGTAAAGAAGGTGATTCTTTTCTTGTGGAATGGAATGAAAGTGAAGGAGCCATAAAGAGGACTTATTCTGGGTTTAGAAAGAAATCAGCTGGTGTTGTGCAGTTTGACACAACTCAAAATCACTTCTTGGCTGTGGGTGAAGATAGCCAGATAAAATTTTGGGACATGGACAATATAAATATTCTTACAACTATAGATGCTGATGGTGGTCTCCCGAGTCTTCCACGCTTGAGATTCAATAAGGAGGGGAATCTTCTTGCTGTTACTACTGCTGACAATGGGATTAAGATACTGGGAAACCCTGCTGGTATGAGATCCTTGAGAACAGTTGAGGCCCCACCTTTTGAAGCACTAAGATCACCCATTGAAGCAGCTGCTATAAAGCAGGGTTCTGGCTCTTCTGTTCCAAATGCTACTCCTGTCAATTGTAAAGTTGAAAGGAGCTCTCCTATCAGGCCGTCTCCTATCCTTAATGGAGTTGATTCTGTGCCCAGAAGCATGGAGAAACCAAGAATATTGGAGGAAGTTTCAGATAAGGCCAAACCCTGGCAGTTAACGGAAATTTTAGACCAAGCTCAATGCAGGCTGGTTACCATGCCTGAGAGTTCAGATTCGAATAATAAGGTTGCAAGGCTTCTTTATACAAATTCTGGTGTTGGTATTCTGGCACTTGGTTCGAATGGTACTCAAAAGTTGTGGAAGTGGACACGCAATGAACAAAATCCAAGTGGCAAGGCCACTGCTAATGTTGTTCCACAATATTGGCAACCGAACAGTGGTCTTCTTATGACCAACGATATTGTAGGTATCAATTTGGAAGAGGCTGTTCCTTGTATAGCTCTCTCAAAGAATGACTCTTATGTAATGTCAGCTGCTGGTGGGAAAGTGTCACTGTTCAATATGATGACGTTTAAGGTAATGACAACATTTATGCCACCTCCGCCGGCTTCAACTTTCTTAGCATTCCATCCTCAAGATAACAATATTATTGCCATTGGCATGGAGGACTCAACGATCCACATTTATAATGTTAGGGTTGATGAGGTAAAATCCAAGTTAAAAGGCCATCAGAAGCGCATTACTGGTCTTGCTTTCTCCACCAACCTCAACATATTGGTTTCATCAGGTGCTGATGCTCAGCTCTGTTTATGGAGCATTGATTCATGGGACAAGAGGAAATCAGTTCCCATTCAGCTGCCTGCTGGTAAAGCACCTAGTGGTGACACTCGAGTACAGTTCCATGCGGACCAAGTCCGCTTGCTAGTATCCCATGAAACACAGTTAGCAATTTATGATGCATCAAAGATGGAAAGAATTCGCCAGTGGGTCCCCCAAGATGCACTTTCTGCTCCAATAACCTATGCGGCTTACTCTTGCAACAGTCAACTAGTTTATGCTTCCTTTTCTGATGGCAACATCGGGGTATTTGATGCCGATACTCTAAGACTTAGATGTCGTGTTGCTCCCTCAGCTTATTTGTCGCAGGCAGTGTTGACTGGGAGTCAATCTGTGTATCCGTTAGTAGTTGCAGCACATCCACAAGAACCCAGCCAATTTGCAGTTGGGTTGACAGATGGAACTGTTAAAGTGATTGAACCACTGGAATCTGAAGGGAAGTGGGGCGTAAGTCCACCTGTTGATAATGGGATGTTAAATGGCAGGGTGGCCTCCTCTTCGACGGCTAACAACCATGCTGCTGACCAAGTTCAAAGATGA
Protein Sequence
- >Solyc01g100050.3.1
MSSLSRELVFLILQFLEEEKFKESVHKLEQESGFFFNMKYFEEKVHAGEWDEVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDKQDKAKAVEILVSDLKVFSTFNEDLYKEITQLLTLTNFRENEQLSKYGDTKTARSIMLIELKKLIEANPLFREKLVFPTLRSSRLRTLINQSLNWQHQLCKNPRPNPDIKTLFTDHTCTPPNGAVAPTPVNLPPAAIAKPAAFTALGAHGPFPPAAAAAANANALAGWMANAAASSSVQAAVVTASSLPVPPNQVSILKRPLTPPATLGMLDYQSADHEQLMKRLRPAQSVEEVTYPTVRQQASWSLDDLPRTVAFTLPQGSSVTSMDFHPSHHTYLLVGSTNGEITLWEVATREKLVAKAFKIWDVQACTLTFQASASKDAPFSVSRVAWSPDGTFVGVAFSKHLVHLYATVGTNDLRQHLEMDAHAGSVNDLAFAYPNKQLCIVTCGDDKLIKVWDITGRKLFNFEGHEAPVYSICPHQKESIQFIFSTAIDGKIKAWLYDNMGSRVDYDAPGHWCTTMLYSADGTRLFSCGTGKEGDSFLVEWNESEGAIKRTYSGFRKKSAGVVQFDTTQNHFLAVGEDSQIKFWDMDNINILTTIDADGGLPSLPRLRFNKEGNLLAVTTADNGIKILGNPAGMRSLRTVEAPPFEALRSPIEAAAIKQGSGSSVPNATPVNCKVERSSPIRPSPILNGVDSVPRSMEKPRILEEVSDKAKPWQLTEILDQAQCRLVTMPESSDSNNKVARLLYTNSGVGILALGSNGTQKLWKWTRNEQNPSGKATANVVPQYWQPNSGLLMTNDIVGINLEEAVPCIALSKNDSYVMSAAGGKVSLFNMMTFKVMTTFMPPPPASTFLAFHPQDNNIIAIGMEDSTIHIYNVRVDEVKSKLKGHQKRITGLAFSTNLNILVSSGADAQLCLWSIDSWDKRKSVPIQLPAGKAPSGDTRVQFHADQVRLLVSHETQLAIYDASKMERIRQWVPQDALSAPITYAAYSCNSQLVYASFSDGNIGVFDADTLRLRCRVAPSAYLSQAVLTGSQSVYPLVVAAHPQEPSQFAVGLTDGTVKVIEPLESEGKWGVSPPVDNGMLNGRVASSSTANNHAADQVQR*