Gene Details:

• Gene ID: Solyc10g008950
• Gene Symbol: SlGBP1
• Gene Name: GB1/RHD3-type G domain-containing protein
• Genome: Tomato Genome version SL4.0
• Species: Solanum lycopersicum

Functional Descriptions:

• The Tomato Guanylate-Binding Protein SlGBP1 Enables Fruit Tissue Differentiation by Maintaining Endopolyploid Cells in a Non-Proliferative State.
• The data indicate that disruption of the SlGBP1 gene, encoding GUANYLATE BINDING PROTEIN1, induces early termination of endoreduplication followed by late divisions of polyploid mesocarp cells, which consequently acquire the characteristics of young proliferative cells.
• SlGBP1 acts as an inhibitor of cell division, a function conserved with the human hGBP-1 protein.
• This study reveals a crucial role of plant GBPs in the control of cell cycle genes, and thus, in cell fate maintenance. We propose that SlGBP1 acts as an inhibitor of cell division, a function conserved with the human hGBP-1 protein.

Function-related keywords:

• cell-division ,  cell-cycle

Literature:

• The Tomato Guanylate-Binding Protein SlGBP1 Enables Fruit Tissue Differentiation by Maintaining Endopolyploid Cells in a Non-Proliferative State.   DOI:  10.1105/tpc.20.00245 ;  PMID:  32753430

Related News:

• the Plant Cell | SlGBP1基因在调控番茄果皮厚度变化中起重要作用

Gene Resources:

• NCBI ID: 101250056
• UniProt accessions: A0A3Q7ICM0

Sequences: