Gene Details:

• Gene ID: Solyc02g077840
• Gene Symbol: SlERF.F12
• Gene Name: AP2/ERF domain-containing protein
• Genome: Tomato Genome version SL4.0
• Species: Solanum lycopersicum

Functional Descriptions:

• SlERF.F12 modulates the transition to ripening in tomato fruit by recruiting the co-repressor TOPLESS and histone deacetylases to repress key ripening genes.
• SlERF.F12, a member of the ERF.F subfamily containing Ethylene-responsive element-binding factor-associated Amphiphilic Repression (EAR) motifs, negatively regulates the onset of tomato (Solanum lycopersicum) fruit ripening by recruiting the co-repressor TOPLESS 2 (TPL2) and the histone deacetylases (HDAs) HDA1/HDA3 to repress the transcription of ripening-related genes.
• SlERF.F12 interacts with the co-repressor TPL2 via the C-terminal EAR motif and recruits HDAs SlHDA1 and SlHDA3 to form a tripartite complex in vivo that actively represses transcription of ripening genes by decreasing the level of the permissive histone acetylation marks H3K9Ac and H3K27Ac at their promoter regions.
• We demonstrate that SlERF.F12 negatively regulates the onset of tomato fruit ripening by recruiting the co-repressor TOPLESS protein 2 (TPL2) and the histone deacetylases (HDAs) HDA1/HDA3 to repress the transcription of ripening-related genes.

Function-related keywords:

• transcription-factor ,  ethylene

Literature:

• SlERF.F12 modulates the transition to ripening in tomato fruit by recruiting the co-repressor TOPLESS and histone deacetylases to repress key ripening genes.   DOI:  10.1093/plcell/koac025 ;  PMID:  35099538

Related News:

• The Plant Cell | 西红柿不红？四川大学刘明春组首次揭示番茄果实成熟的负调控因子

Gene Resources:

• NCBI ID: 101259210
• UniProt accessions: A0A3Q7F492

Sequences: