Gene Details:

Functional Descriptions:

  • We show that SlDMR6-1, but not SlDMR6-2, is associated with plant immunity. Remarkably, SlDMR6-1 mutants display enhanced resistance to bacterial, oomycete, and fungal pathogens.
  • We also demonstrate that SlDMR6-1 and SlDMR6-2 convert SA into its inactive form, 2,5-DHBA, indicating that they play a role in SA homeostasis.
  • SlDMR6-1 mutants display enhanced resistance against different classes of pathogens, such as bacteria, oomycete, and fungi.
  • We then propose that SlDMR6 duplication in tomato resulted in subsequent subfunctionalization, in which SlDMR6-2 specialized in balancing SA levels in flowers/fruits, while SlDMR6-1 conserved the ability to fine-tune SA levels during pathogen infection of the plant vegetative tissues.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >Solyc03g080190.3.1
    TTCTCAGAAGGATGAATAAGAATATTGTGAGCAAATCTTCTTTCATTTGTAATTCAAAAATTATTACTCCTTCTTTACTTTTCCAATTTAATTATATTTATATGCAACTCCATATATATTATAAGCCATAGATTCCATGGAAACCAAAGTTATTTCTAGCGGAATCAACCACTCTACTCTTCCTCAAAGTTACATCCGACCCGAATCCGATAGACCACGTCTATCGGAAGTGGTCGATTGTGAAAATGTTCCAATAATTGACTTAAGTTGCGGAGATCAAGCTCAAATAATTCGTCAAATTGGAGAAGCTTGTCAAACTTATGGTTTCTTTCAGGTAATTAATCATGGTGTACCAAAGGAAGTTGTAGAGAAAATGCTAGGGGTAGCTGGGGAATTTTTCAATTTACCAGTAGAAGAGAAACTAAAATTATATTCAGATGATCCTTCAAAGACCATGAGATTATCAACAAGTTTTAATGTTAAAAAGGAGACAGTTCATAATTGGAGAGATTATCTCAGACTTCATTGTTATCCTCTAGAGAAGTATGCTCCTGAATGGCCTTCTAATCCATCATCTTTCAGGGAAATCGTGAGCAGATATTGCAGGGAAATTCGTCAACTCGGATTTAGATTAGAAGAAGCCATAGCAGAAAGCCTGGGGTTAGATAAAGAGTGTATAAAAGATGTATTGGGTGAACAAGGACAACATATGGCTATCAATTATTATCCTCCTTGTCCACAACCAGAACTTACTTATGGGCTTCCGGCCCATACTGATCCAAATTCACTTACAATTCTTCTTCAAGACTTGCAAGTTGCGGGTCTTCAAGTTCTTAAAGATGGCAAATGGTTAGCTGTAAAACCTCAACCTGACGCCTTTGTCATTAATCTTGGGGATCAATTGCAGGCAGTAAGTAACGGTAAGTACAGAAGTGTATGGCATCGAGCTATTGTGAATTCAGATCAAGCTAGGATGTCAGTGGCTTCGTTTCTATGTCCGTGTGATAGCGCGAAAATCAGTGCACCAAAGCTGCTGACAGAAGATGGATCTCCAGTGATTTATCAAGACTTTACGTATGCTGAGTATTACAACAAGTTCTGGAGCAGGAATTTGGACCAGCAACATTGTTTGGAACTTTTCAAGAACTAAGTCGTTTGGTTCATAGGGATGTCCCGGAAGTAAGTTTAGAATTAAATTTATACTTTGTTTGGTTGAGGGTGAGATAAATCTAGACGTTCAATCAAACAGAATATAAATTTAATCTCAAACTTAATCCTGAATATCCCATCCAATGCCAATATAATTTAGTCAGCAAACCAAATGACGCGAAATCATAAGTAGTACCACTTTCAGTACTTAATTTTTTTTTTTAGATTCGAGTTATAGTTCTGGGGTGGGAATTAAACTAGGTTGAAATAAGAAAAATGGAGACACCAATTACCTTGTTGATTTACCCAAATTACATGACTGCTCCAATGTTTTGTTACTGTCAAGTAGTGTTAGCAATTGGGCTGGAGAAATGGACTACGTTGGAATAATAATAATTTGTAGCAGTAATTTCATTGTTTACTGTATTTACTTCACTGTATGAGTTATTGAAGGCTATGATAATATATTAAAACA
CDS Sequence
  • >Solyc03g080190.3.1
    ATGGAAACCAAAGTTATTTCTAGCGGAATCAACCACTCTACTCTTCCTCAAAGTTACATCCGACCCGAATCCGATAGACCACGTCTATCGGAAGTGGTCGATTGTGAAAATGTTCCAATAATTGACTTAAGTTGCGGAGATCAAGCTCAAATAATTCGTCAAATTGGAGAAGCTTGTCAAACTTATGGTTTCTTTCAGGTAATTAATCATGGTGTACCAAAGGAAGTTGTAGAGAAAATGCTAGGGGTAGCTGGGGAATTTTTCAATTTACCAGTAGAAGAGAAACTAAAATTATATTCAGATGATCCTTCAAAGACCATGAGATTATCAACAAGTTTTAATGTTAAAAAGGAGACAGTTCATAATTGGAGAGATTATCTCAGACTTCATTGTTATCCTCTAGAGAAGTATGCTCCTGAATGGCCTTCTAATCCATCATCTTTCAGGGAAATCGTGAGCAGATATTGCAGGGAAATTCGTCAACTCGGATTTAGATTAGAAGAAGCCATAGCAGAAAGCCTGGGGTTAGATAAAGAGTGTATAAAAGATGTATTGGGTGAACAAGGACAACATATGGCTATCAATTATTATCCTCCTTGTCCACAACCAGAACTTACTTATGGGCTTCCGGCCCATACTGATCCAAATTCACTTACAATTCTTCTTCAAGACTTGCAAGTTGCGGGTCTTCAAGTTCTTAAAGATGGCAAATGGTTAGCTGTAAAACCTCAACCTGACGCCTTTGTCATTAATCTTGGGGATCAATTGCAGGCAGTAAGTAACGGTAAGTACAGAAGTGTATGGCATCGAGCTATTGTGAATTCAGATCAAGCTAGGATGTCAGTGGCTTCGTTTCTATGTCCGTGTGATAGCGCGAAAATCAGTGCACCAAAGCTGCTGACAGAAGATGGATCTCCAGTGATTTATCAAGACTTTACGTATGCTGAGTATTACAACAAGTTCTGGAGCAGGAATTTGGACCAGCAACATTGTTTGGAACTTTTCAAGAACTAA
Protein Sequence
  • >Solyc03g080190.3.1
    METKVISSGINHSTLPQSYIRPESDRPRLSEVVDCENVPIIDLSCGDQAQIIRQIGEACQTYGFFQVINHGVPKEVVEKMLGVAGEFFNLPVEEKLKLYSDDPSKTMRLSTSFNVKKETVHNWRDYLRLHCYPLEKYAPEWPSNPSSFREIVSRYCREIRQLGFRLEEAIAESLGLDKECIKDVLGEQGQHMAINYYPPCPQPELTYGLPAHTDPNSLTILLQDLQVAGLQVLKDGKWLAVKPQPDAFVINLGDQLQAVSNGKYRSVWHRAIVNSDQARMSVASFLCPCDSAKISAPKLLTEDGSPVIYQDFTYAEYYNKFWSRNLDQQHCLELFKN*