Gene Details:

Functional Descriptions:

  • A tomato (Solanum lycopersicum) APETALA2/ERF gene, SlAP2a, is a negative regulator of fruit ripening.
  • Here we describe an APETALA2 transcription factor (SlAP2a) identified through transcriptional profiling of fruit maturation that is induced during, and which negatively regulates, tomato fruit ripening.
  • SlAP2a, a homolog of SlAP2c, acts upstream of SlAP2c and alleviates the SlAP2c-induced repression of lycopene biosynthesis genes by inhibiting SlAP2c transcription during fruit ripening.
  • Identified a transcriptional cascade mediated by AP2 family members that regulates lycopene biosynthesis during fruit ripening in tomato, laying the foundation for the manipulation of carotenoid metabolism in plants.
  • RNAi repression of SlAP2a results in fruits that over-produce ethylene, ripen early and modify carotenoid accumulation profiles by altering carotenoid pathway flux.
  • These results suggest that SlAP2a functions during normal tomato fruit ripening as a modulator of ripening activity and acts to balance the activities of positive ripening regulators.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >Solyc11g069190.2.1
    ATGGAAATTGATCTGAATCATGCATTAGTGAGTGAAGTGGAGAAGAATGTATGTTGTAATGAAGAATGTGATAAAGGGGGTGGTGGGGGTTGTGTTAATTGCTCTTTGTACACTTCCACTACTTCTTCTTGTTCTTCAAATGTATCTTCATCTTCTTCACTTGCTCTTACCTCAATTTATAAAGAGCTTTGGCATGCTTGTGCTGGTCCTCTTACTAGTTTACCCAAGAAAGGAAATGTAGTGGTTTATTTCCCTCAAGGTCATATGGAAGAAGCTGTTTCTGCTTTTCCATTTTCACCTGTCAAGATTGATTTACCAACTTTTGGTCTTCAGCCTCAGATCTTCTGTAGAGTGGAAGATGTCCAATTGCTTGCAAATAAGGAAAATGATGAGGTGTATACACAGCTCACTCTTCTTCCTCTTCCAGAGTCAATGGCTATAAGCTTAGAGGGGAAAGAACATGAAGATTCGGGGACGGATGAGGAAGGGAATGGAGTCAATCCAGGGAAATCAGCTTCTCACATGTTCTGTAAAACGCTGACTGCTTCGGATACCACCACCCATGGTGGCTTTTCAGTTCCCCGTCGAGCAGCTGAAGACTGCTTCCCCCCTCTGGATTACAAAGAGCAAAGACCCTCACAGGAGCTAATTGCTAAGGATCTGCACGGAGTAGAGTGGAAATTTCGTCACATTTATAGAGGCCAGCCAAGGCGACATTTGCTCACTACTGGATGGAGTATCTTTGTCAGCCAAAAGAATCTTGTCTCAGGGGATGCAGTTCTCTTCTTGAGGGGAGAAGGTGGAAATCTCAGACTGGGAATAAGAAGAGCTGCAAGACCTAGAAATGGGCTTCCTGAATCGATAATCAAAAGTCAATATTCTGGACCGGATGTTCTTTCGTCAGTTGCTACAGCCCTATCAGCAAAGAGCACTTTCCATGTTTTCTATAGCCCAAGGGCAAGTCATGCTGATTTCGTTGTACCTTACCAAAAGTACGTGAAAGCCATCAACTCTCGGATTCCTGTTGGGACAAGATTTAAAATGAAATTTGATTTGGATGATTCACCTGAAAGAAGGTACAGCGGTGTAGTGACTGGGATAAGCGATATGGATCCCTTTAGATGGCCCAACTCTAAATGGAGATGCTTGATGGTCAGATGGGATGAAGATATAATGAGTAATCATCAGGAACGGGTTTCTCCTTGGGAAATTGATTCTTCAGTTTCCTTACCACCACTGAGCATTCAGTCCTCACCAAGACTGAAGAAACTGCGGACTAGTCAGCAGGCACCATCAGTACTGGACAGCCATTTTGCTGGAGGGAGTGCTCTTTTAGACTTTGAGGAGTCAATAAGATCCTCCAAGGTCTTGCAAGGTCAAGAAAATTTAGGTCTGATATCACCTCCCTATGGTTGTGATAAACCAGTCCGCCCACTGGATTTCGAGCTGCAAAGAGTAGCTCGTCACAATCTCATGCCAAATGGTGTAGAGAACATTATTGTTGGTGACTTTGTGAAAACTCAGCCTCCAACAACCTACACAGGCTTTCTGGAATCCAATAGGTTTCCAAAGGTCTTGCAAGGTCAAGAAATTTGCTCGTTGAGATCCCTTACTGGAAAAGGTGATGTTAATTTTGGTGCTTGGGGAAAACCTGAATTTGGTTGCAATGTTTTCGGCACATATCAGAGGCCGAGAGCCAATTTCTATCCTCTCGCTTCTGAAGGGGCGAGGAATGTGTTTTTACCTTACAATGCGATGTATAGAGCTGGACAAGATCCCGTGGTTCCCTCCTACAGTACTAATTTCCAAAGAGAAAATCCTACCTTGAACCAGAATTCAATCCAAAATGTGGTTAGGAGGGAAGAAGTTGGAATGCCAAAGTTTGTAAATGAGCAGAGGCCACCGGAGATGTCTAAAGTGTCCATTCCAGAGAACCATTTCAAGAATGAAAATGACGACTCCTTCAATGCACAGGCTCCATGTAAACTGTTTGGCTTTTCCTTGACGAAAGAACCATCTACTCCTAGCTCGCAGAGTTCTGGTAAGAGGAGCTGTACTAAGGTTCACAAACAAGGCAGCTTGGTTGGACGAGCCATTGATCTCTCGAGATTGAATGGCTATGACGACTTGCTGGTTGAGTTGGAGAGGCTTTTCAACATGGAAGACCTCTTAAGAGATCCCAACAAGGGGTGGCGAATCTTGTACACTGACAGTGAGAATGACATGATGGTTGTCGGAGATGATCCATGGCATGAGTTCTGTGAGGTAGTATCCAAGATCCATATATACACTCAAGAAGAAGTGGAGAAAATGACTATTGAGGGGATCAGCGATGACACTCAAAGTTGTTTGGAGGAGGCACCAGCAATCATGGATGTCTCAAAGTCTTCTTCAGTTGGCCAGCCTGATTCATCTCCAACTGTAATCAGGATTTGAATAAAGTTTGAATGGAGTACCTATGA
CDS Sequence
  • >Solyc11g069190.2.1
    ATGGAAATTGATCTGAATCATGCATTAGTGAGTGAAGTGGAGAAGAATGTATGTTGTAATGAAGAATGTGATAAAGGGGGTGGTGGGGGTTGTGTTAATTGCTCTTTGTACACTTCCACTACTTCTTCTTGTTCTTCAAATGTATCTTCATCTTCTTCACTTGCTCTTACCTCAATTTATAAAGAGCTTTGGCATGCTTGTGCTGGTCCTCTTACTAGTTTACCCAAGAAAGGAAATGTAGTGGTTTATTTCCCTCAAGGTCATATGGAAGAAGCTGTTTCTGCTTTTCCATTTTCACCTGTCAAGATTGATTTACCAACTTTTGGTCTTCAGCCTCAGATCTTCTGTAGAGTGGAAGATGTCCAATTGCTTGCAAATAAGGAAAATGATGAGGTGTATACACAGCTCACTCTTCTTCCTCTTCCAGAGTCAATGGCTATAAGCTTAGAGGGGAAAGAACATGAAGATTCGGGGACGGATGAGGAAGGGAATGGAGTCAATCCAGGGAAATCAGCTTCTCACATGTTCTGTAAAACGCTGACTGCTTCGGATACCACCACCCATGGTGGCTTTTCAGTTCCCCGTCGAGCAGCTGAAGACTGCTTCCCCCCTCTGGATTACAAAGAGCAAAGACCCTCACAGGAGCTAATTGCTAAGGATCTGCACGGAGTAGAGTGGAAATTTCGTCACATTTATAGAGGCCAGCCAAGGCGACATTTGCTCACTACTGGATGGAGTATCTTTGTCAGCCAAAAGAATCTTGTCTCAGGGGATGCAGTTCTCTTCTTGAGGGGAGAAGGTGGAAATCTCAGACTGGGAATAAGAAGAGCTGCAAGACCTAGAAATGGGCTTCCTGAATCGATAATCAAAAGTCAATATTCTGGACCGGATGTTCTTTCGTCAGTTGCTACAGCCCTATCAGCAAAGAGCACTTTCCATGTTTTCTATAGCCCAAGGGCAAGTCATGCTGATTTCGTTGTACCTTACCAAAAGTACGTGAAAGCCATCAACTCTCGGATTCCTGTTGGGACAAGATTTAAAATGAAATTTGATTTGGATGATTCACCTGAAAGAAGGTACAGCGGTGTAGTGACTGGGATAAGCGATATGGATCCCTTTAGATGGCCCAACTCTAAATGGAGATGCTTGATGGTCAGATGGGATGAAGATATAATGAGTAATCATCAGGAACGGGTTTCTCCTTGGGAAATTGATTCTTCAGTTTCCTTACCACCACTGAGCATTCAGTCCTCACCAAGACTGAAGAAACTGCGGACTAGTCAGCAGGCACCATCAGTACTGGACAGCCATTTTGCTGGAGGGAGTGCTCTTTTAGACTTTGAGGAGTCAATAAGATCCTCCAAGGTCTTGCAAGGTCAAGAAAATTTAGGTCTGATATCACCTCCCTATGGTTGTGATAAACCAGTCCGCCCACTGGATTTCGAGCTGCAAAGAGTAGCTCGTCACAATCTCATGCCAAATGGTGTAGAGAACATTATTGTTGGTGACTTTGTGAAAACTCAGCCTCCAACAACCTACACAGGCTTTCTGGAATCCAATAGGTTTCCAAAGGTCTTGCAAGGTCAAGAAATTTGCTCGTTGAGATCCCTTACTGGAAAAGGTGATGTTAATTTTGGTGCTTGGGGAAAACCTGAATTTGGTTGCAATGTTTTCGGCACATATCAGAGGCCGAGAGCCAATTTCTATCCTCTCGCTTCTGAAGGGGCGAGGAATGTGTTTTTACCTTACAATGCGATGTATAGAGCTGGACAAGATCCCGTGGTTCCCTCCTACAGTACTAATTTCCAAAGAGAAAATCCTACCTTGAACCAGAATTCAATCCAAAATGTGGTTAGGAGGGAAGAAGTTGGAATGCCAAAGTTTGTAAATGAGCAGAGGCCACCGGAGATGTCTAAAGTGTCCATTCCAGAGAACCATTTCAAGAATGAAAATGACGACTCCTTCAATGCACAGGCTCCATGTAAACTGTTTGGCTTTTCCTTGACGAAAGAACCATCTACTCCTAGCTCGCAGAGTTCTGGTAAGAGGAGCTGTACTAAGGTTCACAAACAAGGCAGCTTGGTTGGACGAGCCATTGATCTCTCGAGATTGAATGGCTATGACGACTTGCTGGTTGAGTTGGAGAGGCTTTTCAACATGGAAGACCTCTTAAGAGATCCCAACAAGGGGTGGCGAATCTTGTACACTGACAGTGAGAATGACATGATGGTTGTCGGAGATGATCCATGGCATGAGTTCTGTGAGGTAGTATCCAAGATCCATATATACACTCAAGAAGAAGTGGAGAAAATGACTATTGAGGGGATCAGCGATGACACTCAAAGTTGTTTGGAGGAGGCACCAGCAATCATGGATGTCTCAAAGTCTTCTTCAGTTGGCCAGCCTGATTCATCTCCAACTGTAATCAGGATTTGA
Protein Sequence
  • >Solyc11g069190.2.1
    MEIDLNHALVSEVEKNVCCNEECDKGGGGGCVNCSLYTSTTSSCSSNVSSSSSLALTSIYKELWHACAGPLTSLPKKGNVVVYFPQGHMEEAVSAFPFSPVKIDLPTFGLQPQIFCRVEDVQLLANKENDEVYTQLTLLPLPESMAISLEGKEHEDSGTDEEGNGVNPGKSASHMFCKTLTASDTTTHGGFSVPRRAAEDCFPPLDYKEQRPSQELIAKDLHGVEWKFRHIYRGQPRRHLLTTGWSIFVSQKNLVSGDAVLFLRGEGGNLRLGIRRAARPRNGLPESIIKSQYSGPDVLSSVATALSAKSTFHVFYSPRASHADFVVPYQKYVKAINSRIPVGTRFKMKFDLDDSPERRYSGVVTGISDMDPFRWPNSKWRCLMVRWDEDIMSNHQERVSPWEIDSSVSLPPLSIQSSPRLKKLRTSQQAPSVLDSHFAGGSALLDFEESIRSSKVLQGQENLGLISPPYGCDKPVRPLDFELQRVARHNLMPNGVENIIVGDFVKTQPPTTYTGFLESNRFPKVLQGQEICSLRSLTGKGDVNFGAWGKPEFGCNVFGTYQRPRANFYPLASEGARNVFLPYNAMYRAGQDPVVPSYSTNFQRENPTLNQNSIQNVVRREEVGMPKFVNEQRPPEMSKVSIPENHFKNENDDSFNAQAPCKLFGFSLTKEPSTPSSQSSGKRSCTKVHKQGSLVGRAIDLSRLNGYDDLLVELERLFNMEDLLRDPNKGWRILYTDSENDMMVVGDDPWHEFCEVVSKIHIYTQEEVEKMTIEGISDDTQSCLEEAPAIMDVSKSSSVGQPDSSPTVIRI*