Gene Details:

• Gene ID: Solyc02g079220
• Gene Symbol: LeHT1
• Gene Name: hexose transporter 1
• Genome: Tomato Genome version SL4.0
• Species: Solanum lycopersicum

Functional Descriptions:

• Involvement of the Hexose Transporter Gene LeHT1 and of Sugars in Resistance of Tomato to Tomato Yellow Leaf Curl Virus.
• Previously, we demonstrated that the hexose transporter gene LeHT1 is up-regulated upon infection in R plants and its silencing in R plants (RH) leads to the collapse of resistance.
• In R plants where LeHT1 has been silenced , the hexose transporter is not expressed, and hence hexoses cannot be internalized into the cell in order to act as defense signaling molecules, likely decreasing the PTM effect, and inducing the collapse of resistance.
• These results demonstrate the cardinal role of LeHT1 in regulating sugar content in R plants. In all tomato plants, the hexose content correlated with the expression level of LeHT1.
• Tomato yellow leaf curl virus infection of a resistant tomato line with a silenced sucrose transporter gene LeHT1 results in inhibition of growth, enhanced virus spread, and necrosis.
• They demonstrate that the hexose transporter LeHT1 is essential for the expression of natural resistance against TYLCV and its expression correlates with inhibition of virus replication and movement.

Function-related keywords:

• leaf ,  resistance ,  defense ,  transporter ,  sugar ,  virus

Literature:

• Involvement of the hexose transporter gene LeHT1 and of sugars in resistance of tomato to tomato yellow leaf curl virus.   DOI:  10.1093/mp/sst036 ;  PMID:  23430051
• Tomato yellow leaf curl virus infection of a resistant tomato line with a silenced sucrose transporter gene LeHT1 results in inhibition of growth, enhanced virus spread, and necrosis.   DOI:  10.1007/s00425-009-1072-6 ;  PMID:  19946703

Related News:

Gene Resources:

• NCBI ID: 543737
• UniProt accessions: D0EXD9

Orthologs:

Sequences: