Gene Details:

Functional Descriptions:

  • LeFRO1 encoding an Fe(III)-chelate reductase protein was isolated from the tomato genome. We show that expression of LeFRO1 in yeast increases Fe(III)-chelate reductase activity. In a transient expression analysis we found that LeFRO1 protein was targeted on the plasma membrane.
  • The differential expression of LeFRO1 and LeIRT1 (an iron-regulated metal transporter gene in tomato) in roots of T3238fer under iron-deficient and -sufficient conditions suggests that the FER gene may regulate expression of LeFRO1 more directly than that of LeIRT1 in tomato roots.
  • These results indicate that LeFRO1 is required in roots and shoots as well as in reproductive organs for iron homeostasis and that its transcription in roots and shoots is regulated by different control mechanisms.
  • Considering the paradoxical expression patterns of FER to LeFRO1, LeIRT1 and LeNRAMP1 in T3238, we speculate that FER is essential, but is not the limited factor for the transcriptional regulation of the three iron uptake genes.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
Protein Sequence