Information report for Ve2
Gene Details
Domain Class Descriptions
- Receptor Like Proteins consists of a leucine-rich receptor-like repeat, a transmembrane region of ~25 AA, and a short cytoplasmic region, with no kinase domain. The extracellular leucine rich repeat (eLRR) shows high homology with the RLKs eLRR. RLPs can recognise avirulence genes in a indirect way like Cf2 that recognise the avirulence gene Avr2 through the cysteine protease Rcr3. There are also some hypotheses about a direct recognition, but this has not yet been demonstrated. RLPs lack an obvious signalling domain, suggesting that defence response activation is mediated through interactions with other partner proteins. Activation of RLP typically results in a rapid accumulation of active oxygen species (AOS), changes in cellular ion fluxes, activation of protein kinase cascades, changes in gene expression and, possibly, targeted protein degradation.
Domain Features
- Domain Class: RLP
- Domain types: TM LRR
Gene Resources
- GenBank: 14269076
- GenBank Locus: AF365929
- UniProt: Q93V91
- RefSeq: NP_001234733.2
- EMBL: AF365929 , AF365930
- AlphaFoldDB: Q93V91
- KEGG: sly:544230
- InterPro: IPR001611 , IPR003591 , IPR013210 , IPR032675 , IPR046956
- PANTHER: PTHR48061 , PTHR48061:SF2
- SUPFAM: SSF52058
- Gene3D: 3.80.10.10
- OrthoDB: Q93V91
- SMR: Q93V91
Homologs
- Actinidia chinensis: CEY00_Acc03001
- Capsicum annuum: T459_23250
- Citrus sinensis: orange1.1g001166m.g
- Lactuca sativa: Lsat_1_v5_gn_9_35521
- Manihot esculenta: Manes.08G094700
- Nicotiana attenuata: A4A49_02578, A4A49_30997
- Poncirus trifoliata: Ptrif.0006s0913
- Populus trichocarpa: Potri.016G120600
- Sesamum indicum: SIN_1003901
- Solanum tuberosum: Soltu.DM.09G008790, Soltu.DM.09G008780
Sequences
DNA Sequence
- >Ve2
ATGAGATTTTTACACTTTCTATGGATCTTCTTCATCATACCCTTTTTGCAAATTTTATTAGGTAATGAGATTTTATTGGTTTCCTCTCAATGTCTTGATGATCAAAAGTCATTGTTGCTGCAGTTGAAGGGCAGCTTCCAATATGATTCTACTTTGTCAAATAAATTGGCAAGATGGAACCACAACACAAGTGAATGTTGTAACTGGAATGGGGTTACATGTGACCTCTCTGGTCATGTGATTGCCTTGGAACTGGATGATGAGAAAATTTCTAGTGGAATTGAGAATGCAAGTGCTCTTTTCAGTCTTCAGTATCTTGAGAGGCTAAATTTGGCTTACAACAAGTTCAATGTTGGCATACCAGTTGGTATAGGCAACCTCACCAACTTGACGTACCTGAATTTATCCAATGCCGGTTTTGTTGGCCAAATTCCTATGATGTTATCAAGGTTAACAAGGCTAGTTACTCTTGATCTCTCAACTCTTTTCCCTGACTTTGCCCAGCCACTAAAACTAGAGAATCCCAATTTGAGTCATTTCATTGAGAACTCAACAGAGCTTAGAGAGCTTTACCTTGATGGGGTTGATCTCTCAGCTCAGAGGACTGAGTGGTGTCAATCTTTATCTTCATATTTGCCTAACTTGACTGTCTTGAGCTTGCGTACTTGTCGAATTTCAGGCCCTATTGATGAATCACTTTCTAAGCTTCACTTTCTCTCTTTCATCCGTCTTGACCAGAACAATCTCTCTACCACAGTTCCTGAATACTTTGCCAATTTCTCAAACTTGACTACCTTGACCCTCTCCTCTTGTAATCTGCAAGGAACATTTCCTAAAAGAATCTTTCAGGTACCAGTCTTAGAGTTTTTGGACTTGTCAACTAACAAATTGCTTAGTGGTAGTATTCCGATTTTTCCTCAAATTGGATCATTGAGGACGATATCACTAAGCTACACCAAGTTTTCTGGTTCATTACCAGACACCATTTCGAACCTTCAAAACCTATCCAGGTTAGAACTCTCCAACTGCAATTTCAGTGAACCAATACCTTCCACAATGGCGAACCTTACCAATCTTGTTTATTTAGATTTCTCCTTCAACAATTTCACTGGTTCCCTCCCATATTTCCAAGGGGCCAAGAAACTCATCTACTTGGACCTTTCACGTAATGGTCTAACTGGTCTCTTGTCTAGAGCTCATTTTGAAGGACTCTCAGAACTTGTCTACATTAATTTAGGGAACAATTCACTCAACGGGAGCCTTCCTGCATATATATTTGAGCTCCCCTCGTTGAAGCAGCTTTTTCTTTACAGCAATCAATTTGTTGGCCAAGTCGACGAATTTCGCAATGCATCCTCCTCTCCGTTGGATACAGTTGACTTGAGAAACAACCACCTGAATGGATCGATTCCCAAGTCCATGTTTGAAGTTGGGAGGCTTAAGGTCCTCTCACTTTCTTCCAACTTCTTTAGAGGGACAGTTCCCCTTGACCTCATTGGGAGGCTGAGCAACCTTTCAAGACTGGAGCTTTCTTACAATAACTTGACTGTTGATGCAAGTAGCAGCAATTCAACCTCTTTCACATTTCCCCAGTTGAACATATTGAAATTAGCGTCTTGTCGGCTGCAAAAGTTCCCCGATCTCAAGAATCAGTCAAGGATGATGCACTTAGACCTTTCAGACAACCAAATATTGGGGGCAATACCAAATTGGATCTGGGGAATTGGTGGTGGAGGTCTCGCCCACCTGAATCTTTCATTCAATCAGCTGGAGTACGTGGAACAGCCTTACACTGTTTCCAGCAATCTTGTAGTCCTTGATTTGCATTCCAACCGTTTAAAAGGTGACTTACTAATACCACCTTCCACTGCCATCTATGTGGACTACTCGAGCAATAATTTAAACAATTCCATCCCAACAGATATTGGAAGATCTCTTGGTTTTGCCTCCTTTTTCTCGGTAGCAAACAATAGCATCACTGGAATAATTCCTGAATCCATATGCAACGTCAGCTACCTTCAAGTTCTTGATTTCTCTAACAATGCCTTGAGTGGAACAATACCACCATGTCTACTGGAATATAGTCCAAAACTTGGAGTGCTGAATCTAGGGAACAATAGACTCCATGGTGTTATACCAGATTCATTTCCAATTGGTTGTGCTCTAATAACTTTAGACCTCAGCAGGAATATCTTTGAAGGGAAGCTACCAAAATCGCTTGTCAACTGCACGTTGTTGGAGGTCCTGAATGTTGGAAATAACAGTCTTGTTGATCGTTTCCCATGCATGTTGAGGAACTCAACCAGCCTGAAGGTCCTAGTCTTGCGCTCCAATAAATTCAATGGAAATCTTACGTGTAATATAACCAAACATAGCTGGAAGAATCTCCAGATCATAGATATAGCTTCCAACAATTTTACTGGTATGTTGAATGCAGAATGCTTTACAAATTGGAGAGGAATGATGGTTGCAAAAGATTACGTGGAGACAGGACGCAATCATATCCAGTATGAGTTCTTACAACTAAGTAACTTGTACTATCAGGATACAGTGACATTAATCATCAAAGGCATGGAGCTGGAGCTTGTGAAGATTCTTAGGGTCTTCACATCTATTGATTTCTCTTCCAATAGATTTCAAGGAAAGATACCAGATACTGTTGGGGATCTTAGCTCACTTTATGTTTTGAACCTGTCACACAATGCCCTCGAGGGACCAATTCCAAAATCAATTGGGAAGCTACAAATGCTTGAATCACTAGACCTGTCAAGAAACCACCTGTCCGGGGAGATCCCCTCAGAGCTTTCAAGTCTCACATTCTTAGCAGTTTTGAACTTATCGTTCAACAATTTGTTTGGAAAAATCCCGCAAAGTAATCAATTTGAAACATTCTCAGCAGAATCCTTTGAAGGAAACAGAGGCCTATGCGGGCTCCCTCTTAACGTCATTTGCAAAAGCGATACTTCAGAGTTGAAACCAGCACCAAGTTCTCAAGATGACTCTTATGATTGGCAGTTCATATTTACGGGTGTGGGATATGGAGTAGGGGCAGCAATCTCCATTGCACCTCTGTTGTTTTACAAGCAAGGAAACAAATACTTTGACAAACATTTGGAGAGAATGCTTAAACTGATGTTTCCTAGATACTGGTTCAGTTACACCAGATTTGACCCTGGGAAGGTTGTGGCTGTGGAACACTATGAAGATGAGACCCCAGATGACACCGAAGATGACGATGAGGGTGGAAAAGAAGCATCTCTTGGGCGTTATTGTGTCTTCTGTAGTAAACTTGATTTTCAGAAAAATGAAGCAATGCATGATCCAAAATGCACTTGTCATATGTCATCATCCCCCAATTCTTTTCCTCCTACGCCGTCCTTTTTTTCACCTTTATTAGTCATATATCACAAAAAGTTTTGA
Protein Sequence
- >Ve2
MRFLHFLWIFFIIPFLQILLGNEILLVSSQCLDDQKSLLLQLKGSFQYDSTLSNKLARWNHNTSECCNWNGVTCDLSGHVIALELDDEKISSGIENASALFSLQYLERLNLAYNKFNVGIPVGIGNLTNLTYLNLSNAGFVGQIPMMLSRLTRLVTLDLSTLFPDFAQPLKLENPNLSHFIENSTELRELYLDGVDLSAQRTEWCQSLSSYLPNLTVLSLRTCRISGPIDESLSKLHFLSFIRLDQNNLSTTVPEYFANFSNLTTLTLSSCNLQGTFPKRIFQVPVLEFLDLSTNKLLSGSIPIFPQIGSLRTISLSYTKFSGSLPDTISNLQNLSRLELSNCNFSEPIPSTMANLTNLVYLDFSFNNFTGSLPYFQGAKKLIYLDLSRNGLTGLLSRAHFEGLSELVYINLGNNSLNGSLPAYIFELPSLKQLFLYSNQFVGQVDEFRNASSSPLDTVDLRNNHLNGSIPKSMFEVGRLKVLSLSSNFFRGTVPLDLIGRLSNLSRLELSYNNLTVDASSSNSTSFTFPQLNILKLASCRLQKFPDLKNQSRMMHLDLSDNQILGAIPNWIWGIGGGGLAHLNLSFNQLEYVEQPYTVSSNLVVLDLHSNRLKGDLLIPPSTAIYVDYSSNNLNNSIPTDIGRSLGFASFFSVANNSITGIIPESICNVSYLQVLDFSNNALSGTIPPCLLEYSPKLGVLNLGNNRLHGVIPDSFPIGCALITLDLSRNIFEGKLPKSLVNCTLLEVLNVGNNSLVDRFPCMLRNSTSLKVLVLRSNKFNGNLTCNITKHSWKNLQIIDIASNNFTGMLNAECFTNWRGMMVAKDYVETGRNHIQYEFLQLSNLYYQDTVTLIIKGMELELVKILRVFTSIDFSSNRFQGKIPDTVGDLSSLYVLNLSHNALEGPIPKSIGKLQMLESLDLSRNHLSGEIPSELSSLTFLAVLNLSFNNLFGKIPQSNQFETFSAESFEGNRGLCGLPLNVICKSDTSELKPAPSSQDDSYDWQFIFTGVGYGVGAAISIAPLLFYKQGNKYFDKHLERMLKLMFPRYWFSYTRFDPGKVVAVEHYEDETPDDTEDDDEGGKEASLGRYCVFCSKLDFQKNEAMHDPKCTCHMSSSPNSFPPTPSFFSPLLVIYHKKF