Information report for M
Gene Details
Domain Class Descriptions
- Contains a central nucleotide-binding (NB) subdomain as part of a larger entity called the NB-ARC domain. C-terminal to the NB-ARC domain lies a leucine-rich repeat (LRR) domain, which is sometimes followed by an extension of variable length. Hence, this group of R proteins is collectively referred to as NB-LRR proteins. If N-terminal region shows homology to the protein domain Interleukin-1 Receptor (IL-1R), called the TIR domain, these proteins are referred to as TIR-NB-LRR or TNL.
Domain Features
- Domain Class: TNL
- Domain types: NBS LRR TIR
Gene Resources
- UniProt: P93244
- EMBL: U73916
- InterPro: IPR000157 , IPR002182 , IPR027417 , IPR032675 , IPR035897 , IPR042197 , IPR044974 , IPR055414
- PANTHER: PTHR11017 , PTHR11017:SF570
- SUPFAM: SSF52058 , SSF52200 , SSF52540
- PROSITE: PS50104
- Gene3D: 1.10.8.430 , 3.40.50.10140 , 3.40.50.300 , 3.80.10.10
- Pfam: PF00931 , PF01582 , PF23282 , PF23598
- SMR: P93244
Sequences
DNA Sequence
- >M
ATGAGTTATTTGAGAGACGTTGCTACTGCGGTTGCCTTGCTTCTTGACAATTTGTGCTGTGGGAGACCAAATCTCAACAATGACAACGAGGATACCATTCAGCAAACAGATTCAACTTCTCCTGTTGTTGATCCCTCTAGTTCATCCCAGTCAATGGATTCAACATCTGTAGTTGATGCCATATCGGACTCCACAAATCCCTCTGCTTCATTTCCCTCCGTGGAGTATGACGTGTTTTTGAGTTTCAGGGGTCCAGATACTCGTTATCAAATCACCGACATCCTCTATCGTTTTCTTTGTCGCTCAAAGATCCACACGTTTAAAGACGATGATGAGCTTCATAAGGGAGAAGAGATAAAGGTCAACCTCCTCAGAGCAATCGACCAGTCGAAAATTTATGTTCCCATCATATCGAGGGGTTATGCCGATAGTAAATGGTGTCTCATGGAGCTTGCAAAAATTGTTCGGCATCAAAAGCTGGACACTCGACAGATTATAATTCCTATTTTTTATATGGTGGATCCAAAAGATGTGAGACATCAGACTGGACCTTATCGAAAGGCATTTCAAAAACACTCAACTAGATATGATGAAATGACCATACGAAGCTGGAAGAATGCTCTAAATGAGGTTGGAGCTTTAAAAGGATGGCACGTGAAAAACAATGACGAGCAAGGAGCTATAGCAGATGAAGTTTCTGCAAATATATGGTCACATATAAGCAAGGAAAATTTCATTTTAGAAACTGATGAGTTGGTTGGAATTGATGATCACGTAGAAGTTATATTAGAAATGTTGAGTCTAGACTCTAAAAGTGTGACAATGGTCGGTCTTTATGGTATGGGCGGAATAGGCAAGACAACTACTGCAAAGGCGGTTTATAACAAGATTTCTTCTCATTTTGATCGATGTTGTTTCGTTGATAATGTACGAGCAATGCAAGAGCAGAAGGATGGCATTTTTATTTTGCAAAAGAAGCTGGTATCTGAAATTTTGAGGATGGATTCTGTTGGATTTACTAATGATAGTGGCGGAAGGAAGATGATAAAGGAGAGAGTTTCGAAGTCCAAAATTCTTGTCGTTCTCGATGATGTTGATGAGAAGTTTAAATTTGAAGATATACTCGGCTGTCCTAAAGATTTTGATTCTGGGACTAGATTCATCATTACTTCAAGAAATCAAAATGTCTTGAGTCGTTTGAATGAGAATCAATGCAAGTTGTATGAAGTTGGATCGATGAGCGAACAACATTCGCTCGAACTCTTCTCCAAACACGCATTCAAAAAGAATACGCCTCCATCGGATTATGAGACTCTAGCAAATGATATCGTATCGACTACAGGAGGACTTCCATTGACTTTGAAGGTTACAGGTTCATTTTTATTCAGACAAGAGATTGGGGTTTGGGAAGATACGTTGGAACAGTTACGTAAAACACTTGACCTTGATGAGGTTTATGATAGGCTAAAAATAAGTTACGATGCCTTGAAGGCGGAGGCAAAAGAGATTTTCTTGGATATAGCCTGCTTCTTCATCGGCCGAAATAAAGAAATGCCGTATTACATGTGGAGCGAGTGCAAATTTTATCCTAAAAGTAATATTATTTTTCTCATTCAAAGATGTATGATACAAGTTGGGGATGATGGGGTGTTAGAAATGCACGACCAACTTAGAGATATGGGTAGAGAAATTGTGAGACGAGAGGATGTGCAACGGCCGTGGAAGAGAAGTAGGATATGGTCGAGAGAAGAAGGAATTGATCTTTTGTTGAACAAAAAGGGATCAAGTCAAGTAAAAGCAATTAGCATACCCAACAATATGCTATATGCTTGGGAGTCGGGTGTCAAGTATGAGTTTAAAAGCGAATGTTTCTTGAATTTGTCAGAGTTGAGATTATTTTTTGTAGGATCAACCACATTGCTTACCGGAGATTTCAATAATCTTCTCCCGAATTTGAAGTGGCTTGACTTGCCACGTTACGCACATGGACTGTATGATCCTCCTGTGACCAATTTTACTATGAAAAAATTGGTAATTCTTGTTTCGACCAATAGCAAAACAGAGTGGAGCCATATGATTAAGATGGCTCCGAGGCTGAAAGTTGTACGACTTTATTCCGACTATGGGGTCTCCCAAAGACTTTCTTTCTGTTGGCGCTTCCCCAAAAGCATTGAGGTATTATCCATGTCTGGGATAGAAATCAAGGAAGTTGATATTGGGGAGTTAAAGAACCTAAAGACGTTGGATCTGACCTCATGTCGAATACAAAAGATAAGTGGGGGAACCTTTGGTATGTTGAAGGGACTCATAGAGCTTCGTCTCGACTCCATCAAGTGTACAAATTTGAGAGAAGTAGTTGCCGATATTGGACAACTTTCGTCTCTCAAAGTCTTGAAAACAGAAGGAGCTCAGGAGGTCCAGTTTGAATTTCCATTAGCTTTGAAGGAGTTATCCACTTCATCTCGGATACCGAATCTTTCACAGTTGTTGGATTTGGAGGTACTGAAGGTTTATGGTTGCAACGATGGATTCGACATCCCTCCTGCTAAGAGTACTGAAGATGAAGGTAGCGTGTGGTGGAAGGCATCCAAGTTGAAGTCTTTGAAACTCTATCGCACAAGAATCAATATAAACGTTGTGGATGCTTCTTCCGGTGGTCGTTATTTACTACCATCGTCGCTAACCTCTCTCGAAATTTATTGGTGTAAAGAACCAACGTGGCTTCCAGGAATAGAGAACTTGGAGAATTTGACTTCGCTGGTAGTCGACGATGTCGACATCTTCCAAACTCTTGGAGGTGATTTGGATGGGCTACAAGGGTTGAGATCGTTGGAAACTCTTACTATTACGGAAGTAAATGGTTTAACTCGGATCAAAGGGCTTATGGATCTCTTGTGTTCTTCTACCTGCAAGTTGGAGAAATTAGAGATTAAAGCATGCCATGACCTCACTGAGATACTCCCATGCGAACTCCACGACCAAACAGTAGTAGTCCCCTCTTTTGAAAAACTGACCATTAGGGATTGTCCACGGCTGGAGGTTGGTCCGATGATACGATCTCTCCCAAAGTTCCCAATGCTAAAGAAGTTGGACCTTGCGGTGGCAAATATAACTAAAGAGGAGGATCTGGATGTGATTGGATCCTTACAAGAGTTGGTTGATTTACGGATAGAGTTAGATGATACATCTTCCGGTATAGAGAGGATAGCTTCCTTGTCGAAGCTGAAAAAGTTAACTACACTCAGAGTGAAGGTGCCGAGTTTGCGGGAGATTGAAGAGCTTGCAGCGTTGAAGTCTTTACAAAGGTTGATTTTAGAGGGTTGCACGTCGTTGGAGAGACTACGTCTGGAGAAGCTGAAGGAGCCAGACATTGGAGGATGCCCTGACCTCACTGAGTTAGTCCAAACAGTAGTAGTATGCCCCTCTTTGGTAGAACTGACCATTAGGGATTGTCCACGGCTGGAGGTTGGTCCGATGATTCGATCTCTCCCAAAGTTCCCAATGCTAAAGAAGTTGGACCTCGCGGTGGCAAATATAATTGAGGAGGATCTGGATGTGATTGGATCCCTAGAAGAGTTGGTTATTTTGTCGTTAAAGTTAGATGATACATCTTCTTCCAGCATAGAGAGGATATCTTTCTTGTCAAAGCTGCAAAAGTTATTTAGACTCAGAGTGAAGGTGTCGAGTTTGCGGGAGATTGAAGGGCTTGCAGAGTTGAAGTCTTTACAACTTTTGTTTCTAAAGGGATGCACGTCGTTGGAGAGACTATGGCCTGATGAACAGCAACTCGATAATAATAAGAGTATGCGGATAGACATCCGAGGATGCAAAAGCTTGAGTGTAGATCATCTCTCTGCACTCAAGAGCACTCTACCGCCCAATGTAAAGATAAGATGGCCGGACGAGAAATATAAGTGA
Protein Sequence
- >M
MSYLRDVATAVALLLDNLCCGRPNLNNDNEDTIQQTDSTSPVVDPSSSSQSMDSTSVVDAISDSTNPSASFPSVEYDVFLSFRGPDTRYQITDILYRFLCRSKIHTFKDDDELHKGEEIKVNLLRAIDQSKIYVPIISRGYADSKWCLMELAKIVRHQKLDTRQIIIPIFYMVDPKDVRHQTGPYRKAFQKHSTRYDEMTIRSWKNALNEVGALKGWHVKNNDEQGAIADEVSANIWSHISKENFILETDELVGIDDHVEVILEMLSLDSKSVTMVGLYGMGGIGKTTTAKAVYNKISSHFDRCCFVDNVRAMQEQKDGIFILQKKLVSEILRMDSVGFTNDSGGRKMIKERVSKSKILVVLDDVDEKFKFEDILGCPKDFDSGTRFIITSRNQNVLSRLNENQCKLYEVGSMSEQHSLELFSKHAFKKNTPPSDYETLANDIVSTTGGLPLTLKVTGSFLFRQEIGVWEDTLEQLRKTLDLDEVYDRLKISYDALKAEAKEIFLDIACFFIGRNKEMPYYMWSECKFYPKSNIIFLIQRCMIQVGDDGVLEMHDQLRDMGREIVRREDVQRPWKRSRIWSREEGIDLLLNKKGSSQVKAISIPNNMLYAWESGVKYEFKSECFLNLSELRLFFVGSTTLLTGDFNNLLPNLKWLDLPRYAHGLYDPPVTNFTMKKLVILVSTNSKTEWSHMIKMAPRLKVVRLYSDYGVSQRLSFCWRFPKSIEVLSMSGIEIKEVDIGELKNLKTLDLTSCRIQKISGGTFGMLKGLIELRLDSIKCTNLREVVADIGQLSSLKVLKTEGAQEVQFEFPLALKELSTSSRIPNLSQLLDLEVLKVYGCNDGFDIPPAKSTEDEGSVWWKASKLKSLKLYRTRININVVDASSGGRYLLPSSLTSLEIYWCKEPTWLPGIENLENLTSLVVDDVDIFQTLGGDLDGLQGLRSLETLTITEVNGLTRIKGLMDLLCSSTCKLEKLEIKACHDLTEILPCELHDQTVVVPSFEKLTIRDCPRLEVGPMIRSLPKFPMLKKLDLAVANITKEEDLDVIGSLQELVDLRIELDDTSSGIERIASLSKLKKLTTLRVKVPSLREIEELAALKSLQRLILEGCTSLERLRLEKLKEPDIGGCPDLTELVQTVVVCPSLVELTIRDCPRLEVGPMIRSLPKFPMLKKLDLAVANIIEEDLDVIGSLEELVILSLKLDDTSSSSIERISFLSKLQKLFRLRVKVSSLREIEGLAELKSLQLLFLKGCTSLERLWPDEQQLDNNKSMRIDIRGCKSLSVDHLSALKSTLPPNVKIRWPDEKYK