Information report for SEVIR_2G166700v2
Gene Details
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Functional Annotation
- Encodes EDM2 (enhanced downy mildew 2). The predicted protein bears typical features of transcriptional regulators. EDM2 contains two putative bipartite nuclear localization signals (NLS) two zinc-finger-like motifs, a Proline-rich region and a large aspartic acid-rich region. Both zinc-finger-like stretches resemble the PHD (plant homeodomain) finger motif. Mutations in EDM2 comprise RPP7 mediated resistance against Hyaloperonospora parasitica isolate Hiks1 (HpHiks1). EDM2 may function as a direct or indirect regulator of RPP7 expression.
Homologous
- Citrullus lanatus: Cla97C09G182340
- Setaria italica: SETIT_028887mg, SETIT_015193mg
- Triticum aestivum: TraesCS5B02G172800
Gene Resources
- Pfam: PF00628 PF13771 PF12678 PF13639
- UniProt: A0A4U6VRD5
- EMBL: CM016553
- OMA: NIWIKLE
- InterPro: IPR001965 , IPR013083 , IPR022702 , IPR055198
- PANTHER: PTHR46235 , PTHR46235:SF3
- Gene3D: 3.30.40.10
- CDD: cd15565
Sequences
CDS Sequence
- >SEVIR_2G166700v2
ATGGCAGCCGCCGCCATGATGATGTCCGACGACGACGATGCGGAGCCGCAGGTCAGCGCGGTGGAGAACTACTACCTTGTTGACTCCCTGAAGCACCCTGTTTGCTTCTCCACCCTGCCGCTCCGGCATAGGGACACCGATGATGTCCCTGAATGCAAGAATAGACTGGGGCTGTGGGGGACAGCAGACCGCATCAAGACGGTGTACAAGGAGGTGGTGGCCTGGAGGCTGGTTCTTGAGGGTAAGCAGCCTGAGATCGCGGTGCTTGTTGCGGATGGTGGTGGGTGGATACGCCTTGTGAAGCCCAAGAACAGCTACGAGGAGATGGTCAGGACTGTGCTGATCACGGCACAGATGCTGCATTTCCTCAGGAGGAAGCCTGATGAGCCAGAGAAGAACTTGTGGAGCCATCTTCGAAAAGTTTTCGACAAGTTTGATGTTAGACCCTCAGAGGATGACTTCAGGGACCACAGCTCACTGATGAAGCATTTTGTGGAGAAAGATCCTGTCTTAGCAAAGTCAGAGATTTTGCGAGTATTTGTTGAAGGACGATCTAGGAAAAATATCAGTGAGGTTGTTGCAGATAACATTGGGACCAAGCAGCCGTTCATTGCTGATGATGAGGACATGGATGAGATGGTCACTGAGGATGCTAATAATGAATCTGATGAAGAGGATGAAGATTTGTTTGATTCAATATGTGCCATTTGTGACAATGGAGGAGACATATTATGCTGTGATGGCCCGTGTATGCGCTCCTTCCATGCAAAAATAGGGAGCGGTGAAGACTCCTATTGTGATACCCTTGGATACACTGAGGCACAAGTTGAGGCAATGAAAATATTCCTGTGCAAGAACTGTGAGTATAAGCAGCATCAATGTTTTATATGTGGAGTGTTGGAGCCTTCAGATGGTGCAGCAGCTAAGGTATTTCTGTGTAACAATGCTACGTGCGGACACTTTTACCACCCCAAATGTGTTGCAAAGCAACTTCACCCTAACAACAGAAATGAAGCCACTGAGTTGGAGAAGAATATAACAGAAGGATTTTCATTTACATGTCCCATTCACTGGTGCTTTCGTTGTAAAGGTTTGGAGGATAGAACACAAGAGCCTTTGCAATTTGCTGTCTGCCGACGCTGTCCGAAGTCATATCATCGAAAGTGTTTGCCAAGAGAAATTTCCTTTCAAGATATTGAAGAGGAGGAAATCATCACAAGGGCTTGGGAGTTATCAAAAAGAATCTTGATTTACTGCCAGGACCATGAGATCAATAGTGAAATTGATACACCTGTCAGGGATCATATAGAGTTTCCAAAGATTCGAAAACCAGCTCAAGGAGCTAAGTTGCTGGTTAAGAAGAAAAAAAGGACTTTCAGTGATGCAGTTCTTGATCAACCTTCGATAGATACTGGGAAAATGAAAGGCATGGTCCGTGTGCAAAAAAGCGAACAAATCAAACAAACCAGCAGGGAAGTTTCTACGAAGAGTTTCACCGAGGACCTTGTTTTCAAACCTGAAAAGAAGAAAGTCAAGCTTTTGAAAGAGAAAATACAGCCAGAACCACGTGTAAGCAGTCCAAAACCTGTAAAAGAGCAAGAGCTGGTAGTTTTGCCTTCATCTGCTACAAGGAAGATTCCCCTGAGTTTATTTCCTATAGTGGATAGTGAAGTTGAAAAGAGGGTCATTGCCATACTGGGAAATGAAGCCTCTAAATTGACACTGAAAGATGTTACAAGGAAATGCAGTGTGCCAACAACTCATGTATACTCTGGCAGGCAGACAGACAAGATTGCGCAGGGAAAGATTGAGCGTTCTGTTCAGGCTGTAGGAGCTGCTTTAAAAAAGCTGGAAAATGGAGGTAATGTCAATGATGCTAAAGCAGTATGTGAACCTGATGTTTTGAGACAGCTTGCAAAATGGCATAGTAAGTTCAGAGTATATTTATCACCTTTTATTCATGGCACACGCTACAGTTCTTTTGGTCGACATTTTACGAAGGTGGAAAAGCTTGTTGAGATTGCTGATAAACTTCACTGGTATGTGGAACCTGGTGACACGATAGTGGATTTCTGTTGTGGTGCAAACGATTTCAGCCGGCTGTTGAAAGAAAAACTTGACAAAGTTCAGAAGAAATGCCATTTCAAGAATTATGATCTTATCCAACCAAAGAATCACTTCGGCTTTGAAAAGAGGGATTGGATGACTGTCAAGCTGAATGAGCTGCCTCGTGGATCTCAACTAATTATGGGGCTTAATCCTCCATTTGGGGTCAAAGCAAGTCTTGCAAACAAATTTATTGACAAAGCATTGTCATTCAAGCCTAAGCTCGTTGTACTAATTGTCCCTAAAGAAACTAAAAGGTTAGATCAAAAGAAGACGCCTTATGATTTGATTTGGGAGGACAGTGAATGTCTTGCTGGGAAGGCATTCTATTTGCCTGGTTCTGTGGATCTTAATGATAAAACAGTTGAAGGGTGGAATGCATCTGCACCACCCCTCTACCTGTGGAGTCGTCCTGATTGGACAAAGAAGCACATGAAAATAGCTGAAGAGCATAGTCACACCAGCATGGGGAAGAAGAAACCTCGCCATGTTGACTCTCTATCAGATGACCCTGTGAGGGAAGAAGCTGAACCTTCTGACAAAATAAAAACTAGATCAGAGAAAGGAAAGGAGAATACAGGAAAAGCATCTTTCCATTCCAAAGAGGATAATATATTGGATGATCTTCCAGTGAGGAAACAAGCTGAGGCTACCAACAAATGGAACTCTAGGTCAGGGAAAGAGAGAGGGACAGACAAGACTGCATGCAATGACAGAGAGGCCAACCTACCTGATGACCATGCTGCTAAGAAGCAAGCTAGATCTGAAGAAGAGAGAGGAACTCTAGGGAAGATTGCAGTCCATGTGAAAGAGGCTAATATGTCAGATAACCTTCCAGTTAAGAAACAATCTGAACCTACCAGCAGGGTCATCCCAGGGAAAGAGAAAGAGAATGGCAGTTATGAAAACAGATCTGATAACAGGAGGAAGTGGACACCTGATCATGTAGAGAGCCTCCCTCCCGAAAAGCAAGTGGAAGTTGCATATGAGGAAACAAAAGTTACTATTCCTAGGAAAGAGAGTATTCATAATGAACACAGAGGTGCTTGCCACGAAAATAGAAGAAATTCTCATGGAGAGGAAATCAAGAGCCGGCACAACTATCAGCAAACAGCAGCAGGGATGCTGAATGTCAAGTCCATGGATGGAGGGGATTCTGACATGAGTATCCCATCCCCTGACAGCAATAATGCTGGAAGCAAATCCAGAAGCTATTCCCCTGCTATACCAACTGAACACCCTTCTGATAGGATAGCCCACCCAGATAGTTACTGTCCCTCAGAAGAACTTTATGACCCTATGCTAAACAGGGCTAATCTTAAGGGAAGTTATTTGGCAAGCAATGATGAATACTTTGATGAACTCAAGTATGCTGACATTGACAATAGCTCAAGGATGAGGGGCTCCAGCATTGATGAAGTAACCAAACCCTATATTGGCGCATCAACCAGTCTGTACAGCTTTCAGTCTAGAGACGATGGCAGCTTCTACAGGCGTCCGAGCTCAGAAGACTTGAACACTACTACTGGGAGGAACCTAGTTGCTGATGTGGCTATGCAAGGACACGGCATAAGATATGATGGCCATGGTGACAGTTGCCAAGCTAGTAAGATCCCGCTAGCCATGGGCTCACGAACACATCTAAGTATGAATGGTGGAACTGGTGCTGATTACCCGTTGGCAAGATTCTCCCTAGGATCTTCTGGTGCTAGATTTAGCCAGCCTGCATCTACTCCCTCTTTTGGGCTCTCAGGTTCAGGCTTACAACGAGGTTCGGTAATGGACAAGTATGGGTACGGGCTCTTGGGTCCAAGTGGGCCACAGAGCTCCATTATTGATAGATATGCTCCCTCTCTTGATGGAAGAAACAACACAAGACCGGAGAGCTCCTTGCCTCAACAGTACCCATTCGGACGACAGGGCTCTTATGGTGGTGGGTGGCCACAGAACTGA
Protein Sequence
- >SEVIR_2G166700v2
MAAAAMMMSDDDDAEPQVSAVENYYLVDSLKHPVCFSTLPLRHRDTDDVPECKNRLGLWGTADRIKTVYKEVVAWRLVLEGKQPEIAVLVADGGGWIRLVKPKNSYEEMVRTVLITAQMLHFLRRKPDEPEKNLWSHLRKVFDKFDVRPSEDDFRDHSSLMKHFVEKDPVLAKSEILRVFVEGRSRKNISEVVADNIGTKQPFIADDEDMDEMVTEDANNESDEEDEDLFDSICAICDNGGDILCCDGPCMRSFHAKIGSGEDSYCDTLGYTEAQVEAMKIFLCKNCEYKQHQCFICGVLEPSDGAAAKVFLCNNATCGHFYHPKCVAKQLHPNNRNEATELEKNITEGFSFTCPIHWCFRCKGLEDRTQEPLQFAVCRRCPKSYHRKCLPREISFQDIEEEEIITRAWELSKRILIYCQDHEINSEIDTPVRDHIEFPKIRKPAQGAKLLVKKKKRTFSDAVLDQPSIDTGKMKGMVRVQKSEQIKQTSREVSTKSFTEDLVFKPEKKKVKLLKEKIQPEPRVSSPKPVKEQELVVLPSSATRKIPLSLFPIVDSEVEKRVIAILGNEASKLTLKDVTRKCSVPTTHVYSGRQTDKIAQGKIERSVQAVGAALKKLENGGNVNDAKAVCEPDVLRQLAKWHSKFRVYLSPFIHGTRYSSFGRHFTKVEKLVEIADKLHWYVEPGDTIVDFCCGANDFSRLLKEKLDKVQKKCHFKNYDLIQPKNHFGFEKRDWMTVKLNELPRGSQLIMGLNPPFGVKASLANKFIDKALSFKPKLVVLIVPKETKRLDQKKTPYDLIWEDSECLAGKAFYLPGSVDLNDKTVEGWNASAPPLYLWSRPDWTKKHMKIAEEHSHTSMGKKKPRHVDSLSDDPVREEAEPSDKIKTRSEKGKENTGKASFHSKEDNILDDLPVRKQAEATNKWNSRSGKERGTDKTACNDREANLPDDHAAKKQARSEEERGTLGKIAVHVKEANMSDNLPVKKQSEPTSRVIPGKEKENGSYENRSDNRRKWTPDHVESLPPEKQVEVAYEETKVTIPRKESIHNEHRGACHENRRNSHGEEIKSRHNYQQTAAGMLNVKSMDGGDSDMSIPSPDSNNAGSKSRSYSPAIPTEHPSDRIAHPDSYCPSEELYDPMLNRANLKGSYLASNDEYFDELKYADIDNSSRMRGSSIDEVTKPYIGASTSLYSFQSRDDGSFYRRPSSEDLNTTTGRNLVADVAMQGHGIRYDGHGDSCQASKIPLAMGSRTHLSMNGGTGADYPLARFSLGSSGARFSQPASTPSFGLSGSGLQRGSVMDKYGYGLLGPSGPQSSIIDRYAPSLDGRNNTRPESSLPQQYPFGRQGSYGGGWPQN