Information report for QL12p024227
Gene Details
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Functional Annotation
- Encodes an auxin receptor that mediates auxin-regulated transcription. It contains leucine-rich repeats and an F-box and interacts with ASK1, ASK2 and AtCUL1 to form SCF-TIR1, an SCF ubiquitin ligase complex. Related to yeast Grr1p and human SKP2 proteins, involved in ubiquitin-mediated processes. Required for normal response to auxin and repressed in response to flagellin. As part of the SCF complex and in the presence of auxin, TIR1 interacts with Aux/IAA transcriptional repressor proteins and mediates their degradation. Mutations in TIR1 block auxin stimulation of flavonoid synthesis.
Homologous
- Cucumis melo: MELO3C015898
- Glycine max: Glyma.03G209400, Glyma.19G206800, GmTIR1C, Glyma.02G152800, GmTIR1A, Glyma.10G021500
- Gossypium hirsutum: Gohir.D08G080700
- Juglans regia: Jr08_12700, Jr11_13940
- Manihot esculenta: MANES_05G067800, MANES_01G214300
- Medicago truncatula: Medtr1g088950
- Prunus avium: Pav_sc0000848.1_g430.1.mk
- Prunus persica: PRUPE_8G253300
- Rosa chinensis: RchiOBHm_Chr6g0292661
- Sesamum indicum: SIN_1012796
- Vitis vinifera: VIT_07s0104g01320
Gene Resources
- Pfam: PF18511 PF18791
- UniProt: A0A7N2N479
- EMBL: LRBV02000012
- AlphaFoldDB: A0A7N2N479
- OMA: ISMVCKS
- InterPro: IPR001611 , IPR001810 , IPR006553 , IPR032675 , IPR036047 , IPR041101 , IPR041567
- PANTHER: PTHR16134 , PTHR16134:SF147
- SUPFAM: SSF52047 , SSF81383
- Gene3D: 1.20.1280.50 , 3.80.10.10
- CDD: cd22159
Sequences
CDS Sequence
- >QL12p024227
ATGAAGATGATGATGGGTAGTTCGTTCCCTGAAGAAGTGTTGGAACACGTGTTCTCTTTCATAGAGAGAGACAGAGACAGGAACGCGATCTCGACCGTGTGTCAATCGTGGTACGAGATCGAACGTTGGAGCCGGAGGAGAGTGTTCGTGGGCAACTGCTACGCTGTCAGCCCCGCGATCTTGATCAAACGGTTCCCGGACGTGAGGTGTTTGGAGCTCAAAGGTAAGCCACACTTCGCTGATTTCAACCTCGTACCCGAAGGTTGGGGCGCCTACGTGGCCCCGTGGATCGAGGCGGCTTCCAAGGCTTATCCTGGGCTCGAAGAGATTCGGTTGAAGCGCATGGTCATCTCGGACGACACCTTGAAACTCATTTCTAAGTCGTTCAAGAACTTTAAGGTTCTTGTGCTTTCTTCTTGTGAAGGTTTTTCGACTAAAGGACTTGCTGCCATTGCTGCTGATTGCAGATCTGGGAGGACACTGGTTAATGTGGAAAATCTAGTCAAGATTACTTGGGTTCTATTTTTTCTTTTTTCTGGGGTGAGGAATTTGAGAGAGCTGGACTTGAGGGAGAGTGAAGTGGAGGACTTGAATCAGTCTAGTGGACATTGGCTCAGCCGTTTTCCTGATAACTACACCTCACTGGTGTCCCTTAACATTGCCTGTTTGAACTCTGAGGTGAGCTTCACAGCCTTGGAATGCCTGGTGGGTAGGTGCCCCAACCTGAGGACTCTTCGGCTCAATCGTGCCGTGCCCTTTGACAGGCTTGCAATCCTACTTCGTCGGGCACCTCAGTTGGTTGAGTTAGGCACTGGGGAAGCGTCTGACTTGCGACCAGATGTTTTCTCGCCACCGGATGTTTTCTCGAACCTATCGGGGGCATTCTCTGGGTGCAAAGAACTTAAGAGCCTGTCTGGTTTTTGGGATGTAGCCCCAGGTTATCTTCCAGTTGTTTATCCTATCTGTCCTAGGTTAACGTCGTTGAACTTGAGCTATGCAGCCACTATCCAAAGTTCTGATCTTATCAAGCTAGTTAGCCAATGTCAGAATTTGCAGAAATTATGGGTGCTGGATTACATTGAAGACTTGGGCCTAGAAGAACTTGCAGCATCTTGCAAGTATCTTCGAGAATTGAGGGTATTTCCGTCAGAGCCATTTGGTGCAGAACCAAATGTATTGTTGACAGAACAGGGACTTGTCTCTGTTTCTGAAGGCTGCCCAAAGCTGCATTCAGTTCTGTACTTCTGCCGTCAAATGTCTAATGAGGCCTTAAGGACCATTGCCAGGAATCGACCTAACATGACAAGGTTTCGTCTTTGTATTATTGAGCCACGGACTCCTGATTACCTTACCCTTGAACCACTTGATGTGGGATTTGGAGCCATTGTTGAGCACTGCAAGGATCTAAGGCGGCTTTCCCTTTCTGGTCTTCTTACTGATCGAGTGTTTAAGTACATTGGGACTTATGGCAAAAAATTAGAGATGCTGTCTGTGGCTTTTGCTGGAGATAGTGATCTGGGGCTCCATCATGTACTCTCTGGTTGTGAAAACCTTAGAAAACTTGAGATTAGGGACTGCCCCTTTGGTGACAAGGCTCTTTTGGCCAATGCTGCAAAGCTGGAGACAATGCGATCCCTTTGGATGTCTTCTTGCTCTGTGAGTTTCGGAGCATGTAAGCTGCTAGGTCAGAAGATGCCGATGCTTAATGTTGAGGTTATTGATGAGAGGGGCCCCCCAGATTCAAGACCAGAAAGCTGTCCAGTTGAGAAGCTCTACATATATAGGACTGTCTCTGGACCAAGATTTGACATGCCTGGTTTTGTTTGGACAAAGGATAAAGATTCTGCATTGGGGCTTTCC
Protein Sequence
- >QL12p024227
MKMMMGSSFPEEVLEHVFSFIERDRDRNAISTVCQSWYEIERWSRRRVFVGNCYAVSPAILIKRFPDVRCLELKGKPHFADFNLVPEGWGAYVAPWIEAASKAYPGLEEIRLKRMVISDDTLKLISKSFKNFKVLVLSSCEGFSTKGLAAIAADCRSGRTLVNVENLVKITWVLFFLFSGVRNLRELDLRESEVEDLNQSSGHWLSRFPDNYTSLVSLNIACLNSEVSFTALECLVGRCPNLRTLRLNRAVPFDRLAILLRRAPQLVELGTGEASDLRPDVFSPPDVFSNLSGAFSGCKELKSLSGFWDVAPGYLPVVYPICPRLTSLNLSYAATIQSSDLIKLVSQCQNLQKLWVLDYIEDLGLEELAASCKYLRELRVFPSEPFGAEPNVLLTEQGLVSVSEGCPKLHSVLYFCRQMSNEALRTIARNRPNMTRFRLCIIEPRTPDYLTLEPLDVGFGAIVEHCKDLRRLSLSGLLTDRVFKYIGTYGKKLEMLSVAFAGDSDLGLHHVLSGCENLRKLEIRDCPFGDKALLANAAKLETMRSLWMSSCSVSFGACKLLGQKMPMLNVEVIDERGPPDSRPESCPVEKLYIYRTVSGPRFDMPGFVWTKDKDSALGLS