Information report for PGSC0003DMG400026239
Gene Details
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Functional Annotation
- A novel protein with a RING finger motif near the amino terminus. Negative regulator of cold responses. Functions as an E3 ligase required for the ubiquitination of ICE1. HOS1 physically interacts with ICE1 and mediates the ubiquitination of ICE1 both in vitro and in vivo. Overexpression represses the expression of CBFs and their downstream genes and confers increased sensitivity to freezing stress.
Homologous
- Arabidopsis thaliana — AT2G39810
Gene Resources
- Pfam: PF13934
- UniProt: M1CHD0
- RefSeq: XP_006359255.1
- AlphaFoldDB: M1CHD0
- KEGG: sot:102605128
- OMA: HKCLLDF
- InterPro: IPR001841 , IPR025151 , IPR044718
- PANTHER: PTHR47358 , PTHR47358:SF2
- PROSITE: PS50089
- OrthoDB: M1CHD0
- eggNOG: ENOG502QUFI
- STRING: 4113.M1CHD0
- HOGENOM: CLU_013617_0_0_1
Sequences
CDS Sequence
- >PGSC0003DMG400026239
ATGGAGAGAAGAAGATTCGACGAATCCTCACTACTTCCTCATTCTGTTACCGGCGGTTCCGGTCTTCGGTCTTCTCCTCCACCTCGCCCTCCGAACTACACTTGTCACCGTGTACAGGGAGCATTGAAGCATTTGGCATCAATTGATCCACTGGAATTATGTGATGAGGCCAAAGTAGAGCACTGCCGAGCAACTAGAGATCTAAGAAGTTGTGGACGACATGTACAGAGTGTGTTGAATTCATGTGGTCATGCCTCTTTATGCGAGGAATGCAGTCAGAGATGTGATGTTTGCCCTATATGTAGGATCCCATTACCAAAAGATGCCAATAGACTTCGACTACGCCTATATTACGAGTGCATAGAGGCAGGTCTCATCTCCAAGAGGTGTGATGACAGATTACAAGAGAAAGAGGACAGTGATAAGCAACTGGTTGCTGATATCCAGCGTCTTTATGCTTTGTTTGATGTGGCACTGGAAAACAATCTGGTTTCTCTAATATGCCACTATGTGACAGATGTTTGTATGGATGAAAGTGCTGTGTCCAGTGATCCCATCATTGCCTTCTTGCTTGATGAAGTGGTGGTCAAAGATTGGTGCAAGAGGACGTTCAACAATATTCTGACCGAGATTCAAGTGATATATAATCTAACCATGAATGAACTGAAAGAGAACTTGAGTTTATTTTTCAAGTTCTCTGTGAAGTTAGGTGGTATCTCTAACGTTATTGATGTCTTGGAATCATCGTTTAAAGGCTCTCTTTCTGCAAAGCTTCATGATTTACACCACCTTCAAGAGAGCATCTTAAAGACAAAACAGCACATGGAGATAATGATTTGGTGTATAAGACATGAGTTCTTGGAGAATGTGAAGTCTAGGCATAAAAATTATGCATCGTGGCGAGCTCTGGTCCGTGAAAGGAAATCTGCTGCAATTAAACGTGCATGGCCCGATTCAGTAAATCATTCTGATGAATACAATGCTTCAACACTCTTTATTGAAGATGCTCTTTCGAATATTGAAGCAGCAGAGCAGGGAGACTTGGATGATCATGAAGAAGAGTTAGCACTTGCCTATTTACAGAAGGATGAGGGCTCTTTATATTCACGGTCAAAAATTGAGGGAATGGCTGGATGCTATCCATTTGAAAGTTTGCGGGCTGCTGCTGACATTCTCTTTTTACGAGGAAGTTCAGACTTGGTAGTTGCAAAACAAGCAATTTTCTTGTATTTTATGTTTGACCGGCAATGGACAGTACCTGATGAGCAGTGGAGACACATCATTGATGATTTTGCTGCCACTTTTGGTGTGACCAGGCACTCGCTATTGGAATCCTTTACATTTTTCCTCTTAGATGATGAAGGAGTTCCGGCTCTGAAGGAAGCCTGTCAACTTCTCCCAGAAATATCAAACCCAACAATCCACCCGAAGGTTGCTCAGGTTCTGTTGGAGCGGGGAAACCCTGATGCAGCTCTCATGGTTCTGAGGTGGTCTGGACAAGATGGCACACAGCTAATTTCACTTCGTGAGGCTGTAACTGCTGTCCGTGTGCGGGTAGAATGTGGACTTTTGACTGAAACATTCACGTATCAGAGGCTTATCTGTGCTAAGATCAAGGAGAAAAAGTTGAGGGATGAACAGTTTCAGAGTGCTTCTGCTGAAGTAGAGGACCAATGCAGGTCGTGGGGTCTCTGGGTGGAGACTCTTGTCACTGAGATTTGTTGTCTGTGCATTAGGAGGAACTTAGTTGACCGCATGATAGAACTGCCATGGACTGCTGATGAGGAGAAGCATCTTCATAAATGTCTGCTGGATTTTGCTGCCGAGGATCCTTCAACGCCCATAGGAAGTCTTCTTGTAGTTTTCTACTTGCAGCGTCATAGATATGTTGAAGCATACCAGGTTGATCAGAAGCTTCAGAGCATGGAGGAGACCTTCATTTCTCAAAATTCTGTCAGTGAAGAAGTCTTAGCGAGGATCAGATCAATAAATCATTGGAGGACTTGTTTGGTTGACAAGGGAGTAGAGTTGTTACCAGATATCATACAACAACAAATAAGGACAGGGAAGTTGCCTGAAGTGGTTGTTACTTGCAATGACACAGTCAACATCTCTGAGAGGTCCAATGCTGTAGCCCAAGAACCTATCATGACCAGTTTATTGGCTAATCCTCCCAGCGATTCTAGCCTCATTCAGCGAGTTGATGTTGTTAAACCTTCTGTTCTTGACGCTCCATCTGTACTTGGGGGATCATTAAATCTGTCGAGCTTTAAAGTTGGGCGTTATAGTTCTCCCAGTTCCCCAGCTTTTTTTAATGATGCTGGAGTATTGAAACCTGAAAGTATCCTTGGGAAAAAATTGAAATTTGATGAGATTTCGACCCCTGCAAGTCGTCGTGTTAATCCTCCTGCTCCTGTAATGAAGATCACCAGGAATTCGTCCATGGAACCTTCTATTAGCCGTCTTCGCAATTCTCAAATATATAGAGTTTCGCCTGAGAAGTCTCAGAATGGGTTTCCAAAGGAATCTTATATTTTTGACCAGACTGCTGCTAACAATGTAAATTCTCTTAGTAGCAACAGAGGCATATTAAAACATTCAGTTGAAGATTCAGACATGAGTTATCATGGTAAACGTCTACTGTCAGATGCTGCTGATAGATCACGGATGTTACCATTAAATGATTCAATGGATGTAACCTGGAGCCATGAAGAAAAGGGTCCTTCCACCGTGCATCTAGAAACCAATGGCGGACCAAGGTGGAGGTCTGATGATACCAGTGAAGACGAGGAAATCCCCTCACTAGATGTATTCGCTGGAGTTGTCTCTCCTGCACACACTTCAAGGGGAGTGAGAAGAAGCAGGAGGATTGCCAGGAGATGA
Protein Sequence
- >PGSC0003DMG400026239
MERRRFDESSLLPHSVTGGSGLRSSPPPRPPNYTCHRVQGALKHLASIDPLELCDEAKVEHCRATRDLRSCGRHVQSVLNSCGHASLCEECSQRCDVCPICRIPLPKDANRLRLRLYYECIEAGLISKRCDDRLQEKEDSDKQLVADIQRLYALFDVALENNLVSLICHYVTDVCMDESAVSSDPIIAFLLDEVVVKDWCKRTFNNILTEIQVIYNLTMNELKENLSLFFKFSVKLGGISNVIDVLESSFKGSLSAKLHDLHHLQESILKTKQHMEIMIWCIRHEFLENVKSRHKNYASWRALVRERKSAAIKRAWPDSVNHSDEYNASTLFIEDALSNIEAAEQGDLDDHEEELALAYLQKDEGSLYSRSKIEGMAGCYPFESLRAAADILFLRGSSDLVVAKQAIFLYFMFDRQWTVPDEQWRHIIDDFAATFGVTRHSLLESFTFFLLDDEGVPALKEACQLLPEISNPTIHPKVAQVLLERGNPDAALMVLRWSGQDGTQLISLREAVTAVRVRVECGLLTETFTYQRLICAKIKEKKLRDEQFQSASAEVEDQCRSWGLWVETLVTEICCLCIRRNLVDRMIELPWTADEEKHLHKCLLDFAAEDPSTPIGSLLVVFYLQRHRYVEAYQVDQKLQSMEETFISQNSVSEEVLARIRSINHWRTCLVDKGVELLPDIIQQQIRTGKLPEVVVTCNDTVNISERSNAVAQEPIMTSLLANPPSDSSLIQRVDVVKPSVLDAPSVLGGSLNLSSFKVGRYSSPSSPAFFNDAGVLKPESILGKKLKFDEISTPASRRVNPPAPVMKITRNSSMEPSISRLRNSQIYRVSPEKSQNGFPKESYIFDQTAANNVNSLSSNRGILKHSVEDSDMSYHGKRLLSDAADRSRMLPLNDSMDVTWSHEEKGPSTVHLETNGGPRWRSDDTSEDEEIPSLDVFAGVVSPAHTSRGVRRSRRIARR