Information report for OPUNC08G10420
Gene Details
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Functional Annotation
- Encodes EDM2 (enhanced downy mildew 2). The predicted protein bears typical features of transcriptional regulators. EDM2 contains two putative bipartite nuclear localization signals (NLS) two zinc-finger-like motifs, a Proline-rich region and a large aspartic acid-rich region. Both zinc-finger-like stretches resemble the PHD (plant homeodomain) finger motif. Mutations in EDM2 comprise RPP7 mediated resistance against Hyaloperonospora parasitica isolate Hiks1 (HpHiks1). EDM2 may function as a direct or indirect regulator of RPP7 expression.
Homologous
- Citrullus lanatus: Cla97C09G182340
- Setaria italica: SETIT_015193mg
- Setaria viridis: SEVIR_6G126000v2, SEVIR_2G166700v2
- Triticum aestivum: TraesCS5B02G172800
Gene Resources
- Pfam: PF00628 PF13771 PF12678 PF13639
- UniProt: A0A0E0LTY5
- OMA: VQPGDMK
- InterPro: IPR001965 , IPR013083 , IPR022702 , IPR055198
- PANTHER: PTHR46235 , PTHR46235:SF3
- Gene3D: 3.30.40.10
- CDD: cd15565
- eggNOG: ENOG502QPIX
- STRING: 4537.A0A0E0LTY5
- HOGENOM: CLU_003552_0_0_1
Sequences
CDS Sequence
- >OPUNC08G10420
ATGATGTCATCGGACGACGACCTTGAGCCTCAGCTCAAGGCGGTGGAGAATTACTACTTCGTTGACGACAACGATGTGCCGGTATCCTTCGATGTCCTGCCGTTCCAGTTCGATGCGGCCGAGGGGGTTGCGTCGTTCAAGAAGGATGTTTACCTGCGGGGGTTCACCGACGGCGGCCTCCAGAAAGTCTACAAGCAGGTGGTAGCCTGGAAGCTAGTCCTAGATGGGGACTCGCCCGAGATCGCGGTGCTTTCGACGGAGGGCAGCTGGATTGCCCTGCTGAAGCCGAGGCCTAGCTACGAGGAGACCATCCGGTCTGTACTGATCACTGTCGAAATGCTTCACTTCGTCCGGAGGAGGCCAACGGTTTCCGAGAAGAACATGTGGGATCACCTCTGTGGGGTTTTCGAGAGATTTTTTGTCAGGCCCTCAGAAGATGACTTTGCGAATCATCAGAATTTAATAAAACTCTTTGCTCAGAGAGACCCAGATTTAGCAAATTCACAGGTTTTGCAAGTCTTAATCAAAGACAAGATTATGGACAAGACCAATGAGGTAGCTCAGGTTGGTCCAAATAATCTTGATATTAAACAAGAGCCAGACATTAAACAAGAGCCAGACGTTAAACAAGAGATAGACATTAAACAAGAGCTGGTTGCTTCTGGTGATGAAATGGAGGAGATAGTTGAAGACAGTATTACAGATGTAACAAACAATGATGATGAAGAGGATGAGGAAGATGGAGACTTGTTTGATTCAGTTTGTGCTATCTGTGATAATGGAGGGGAGCTCTTATGCTGTGAAGGTCCGTGTATGAGGTCCTTCCATGCAAAAATAAGAGATGGTGAAGATTCTTACTGTGCAACCCTAGGGTACACAAAGGCAGAAGTCAAGGCACTAAAAAATTTTGTGTGCAAGAATTGTGAGCATAAGCAGCACCAATGCTTTGTCTGTGGAGAGTTGGAGCCTTCAGATGGGGCAAATGCCAAGGTGTTTCTCTGTAATAATGCAACCTGCGGACACTTCTACCACCCAAAGTGTGTTGCACAATTGCTTCATCCTAACAGCAGGAATGAGGTTTCTGAATTGGAGAAAAAGATTGCGGCTGGGTTTTCATTTACATGCCCTGTACATTGGTGCTTTCATTGTAAAGGCCTAGAAGACAGGACTCAAGAACCACTGCAATTTGCTGTCTGCAGACGTTGCCCAAGATCGTATCATAGAAAATGTTTGCCAAGGGAAATTTCCTTTGAAGATATTGACACGCAGGGCATTATAACCCGTGCATGGGAGCTTTCAAAGAGAATTCTGATCTACTGCTTGGACCATGAAATAGACCTTGATATTGGAACACCACCCAGAGACCATATAAAGTTTCCTCATGTTGAAAAACCAGCTTCTTCTGTAAAGAAGAAAGTCAAAGAACTAGCTGAGAAGAAAAGACGGATTTTTGATGATTCATATGTTTCTGAACCTTTACAGAAGCGTGCAAAGTTAAATGAGAAGTTTAATGCAAAAGGTGACAAAGCTAAAAAAGCTGGTGTGAAAAGTGAATTTGAGGAACAAGTTCTTGAATCTGAAAAAGAAAAAACAAAGAACCTGAAAAAGACAACGCAGACTGAAGAACCTTTGGTTGAGTGTGCTGCTGCTGCAAACAACACAAATCGACCTGTGAAAGAACATGAAAAAGAAATGGGGACTTCATCACTGGATATGGGGAAGATACCCCATAGCTCATTCCCTATTGTGGATAGTGAAACTGAGAAGAGGGTATCGGCTTTGGTAGAAAAGGAGGTCTCTTCCTTGACATTAGCCGATATCTCTAGAAGGTGTGCCATTCCTTCAACATATGCATCCTCTGGCCGGCAGATTGACAAAATCATTATACGAGGCAAGCTTGAGCGTTCAATTCAGGCAGTGCAAGCTGCTTTACAAAAACTGGAAAATGGAAGTGCTGTTGATGACGCTAAAGCAGTCTGTGAATCTGAAGTTTTGAGGCAGTTAACAAGATGGCATAATAAGCTCAGAGTTTACCTTGCACCTTTCATTCATGGCATGCGCTACACGTCTTTTGGACGCCATTTTACAAAGAAGGAGAAGCTCATTGAGATTGTCGAGAAGCTTCATTGGTATGTGCAACCTGGAGATATGCTTACTGATGTTGATAAATTGTTTATGTGGAATGCCATGCCACTCAAACCTTTAACTAACCGTCTGTTGACTCCTCACCCCTTGGTCCAAACTCCAAAGAGTATGATAGAGCAAAATGCTGAGAAGGCACATCTGTTAACTCTTGTTTCGTTGAGTGGAAGTGGGCATGGCAAACGAGAGAACGTGATAATTTTTTTCAATTGTACTTTTACTCAAGTGCCTCCATTTCTGTTCAAGCAGATTGTGGATTTCTCCTGTGGTACAAATGATTTCAGTCAATTCATGAAAGAAAAGCTTGATAAAGTTGGCAAAAGATGCAACTTCAAAAGTTACGATGTTATTCAACCAAAGAACTCCTTCAGTTTTGAGAAGAGGGACTGGATGACTGTGCGTCAAAAGGAACTGCCACATGGATCTAAACTGATCATGGGCCTTAATCCTCCTTTTGGATCAAAAGCAATGCTTGCAAACAAATTCATTGACAAGGCGCTGACCTTCAAACCAAAGCTTATCATATTAATTGTCCCGAAGGAGGCTGAAAGGTTAGATCGAAAGCAGCAACCTTATGATTTGGTATGGGAAGATGATCAAAGACTTTCTGGGAAGTCATTCTATTTACCTGGCTCTTTGGATGTGAGTGACAAACAAATTGACCAATGGAATAAATCTCCACCCCCACTCTATTTGTGGAGTCGCCCAGATTGGACACAGAAGCACAAGAGAATAGCGGAGCAGCATGGGCACACCAAAGCCAAAGTTTTCTCCCATACCGAAGAAGATATGCTTTATCTTTTTGAGGATAGAGCTACGCAGAATCATGATGTCAATAATAAGCAGAACTTCACATCTGGAAAAGGAAAAGAGGCTCGCACAGATGGAAACAAGAACTTCGCTGCTAAGAAACCAGTACAAGCAGACGGCTTTCCTCCAGAAAAGCTAGTAGAAGTTGCATACGAGGAAACAAAGGTTGCTTCTAACAGAAGTGGTATGCATCAATCAGATCAAATTAGTGTTCATGATGAGAGAGATGCACATTCTGACTTTCCGATTTCTCGGTACAACAGTATGAAAGCAAAAGAGGTTTCAAATAGCTCGAGAGACAGTTGGAAATCCGATAATACAGGACATGATGTGAAAGCAGATTCCAATATGAGTATCTCACCCTCAGATTCCAGGAATTTTCTACACAATTCTAGCAACTATGAACCTCCAATGTCAAGTAGAAGTGGTTATACCTCGGAGAGGTTGAGATATCATGATAATTGTTTCGATCATCTTGTAGGAGAGAACTCATCTAGCCTTCAGATGCCAACCTTTGAGGACAGCTATTTCAGATCTGTGAATGAATATGGAGTTGCATCTGTACAAAATAACATTGCCTTTTCCACTGATAATGTTGGTGCCAGCTCAAGGATGTACAGTCCAGATCTTGAGGAGCTGAATAGGCTGTATGCTGGTGATCCTACTGGTAGTGCTTATGGTTCAGTATCTGGTGGAACTGGTGGCAGCTTTTACAGGAGGCAGAACCTCGAGGATTACACCATGGAGGGTAGCGAGTCTGCTCAGATGAATCCAGTTCCTGGTAGAGAGCTGCAGGAAAATGCAGGAACGTATTATGGACACAACAGGGATGGACTTCCCCAAACAGCAATTAACACACCTTCCATGGATATTCGGACGCAGATAAGAATGTATGGCAGACACATGGATGATCATACCCAAACAACCATGAACCCACCTGCCAATGATATTCGAGCACAGATAAGAATGTATGGTCGACATGCCGCTTCTGATCACCAGCACACAAGTAGATACTCTTCTGGGTCTCCAGATGCTAGATTTGAGCAGCCGTCTTCTTTAACTTCATATGGAATGCCGTCTTCGGGTTCGACAGGGAGGTCGATGATAGATAGGTCAATTGATGAAACAAGCTATAGGACTACTGTCCAAAGAGGCCCATACAATGCTTCTGACTTTCGGAGGGATCGGCATCCTGATGCCATGAATTTTGCGCCCCACAAGCAGCATCCATACCCACATCCAGGTTCCTCTGGTGGCTGGGTTGACTAA
Protein Sequence
- >OPUNC08G10420
MMSSDDDLEPQLKAVENYYFVDDNDVPVSFDVLPFQFDAAEGVASFKKDVYLRGFTDGGLQKVYKQVVAWKLVLDGDSPEIAVLSTEGSWIALLKPRPSYEETIRSVLITVEMLHFVRRRPTVSEKNMWDHLCGVFERFFVRPSEDDFANHQNLIKLFAQRDPDLANSQVLQVLIKDKIMDKTNEVAQVGPNNLDIKQEPDIKQEPDVKQEIDIKQELVASGDEMEEIVEDSITDVTNNDDEEDEEDGDLFDSVCAICDNGGELLCCEGPCMRSFHAKIRDGEDSYCATLGYTKAEVKALKNFVCKNCEHKQHQCFVCGELEPSDGANAKVFLCNNATCGHFYHPKCVAQLLHPNSRNEVSELEKKIAAGFSFTCPVHWCFHCKGLEDRTQEPLQFAVCRRCPRSYHRKCLPREISFEDIDTQGIITRAWELSKRILIYCLDHEIDLDIGTPPRDHIKFPHVEKPASSVKKKVKELAEKKRRIFDDSYVSEPLQKRAKLNEKFNAKGDKAKKAGVKSEFEEQVLESEKEKTKNLKKTTQTEEPLVECAAAANNTNRPVKEHEKEMGTSSLDMGKIPHSSFPIVDSETEKRVSALVEKEVSSLTLADISRRCAIPSTYASSGRQIDKIIIRGKLERSIQAVQAALQKLENGSAVDDAKAVCESEVLRQLTRWHNKLRVYLAPFIHGMRYTSFGRHFTKKEKLIEIVEKLHWYVQPGDMLTDVDKLFMWNAMPLKPLTNRLLTPHPLVQTPKSMIEQNAEKAHLLTLVSLSGSGHGKRENVIIFFNCTFTQVPPFLFKQIVDFSCGTNDFSQFMKEKLDKVGKRCNFKSYDVIQPKNSFSFEKRDWMTVRQKELPHGSKLIMGLNPPFGSKAMLANKFIDKALTFKPKLIILIVPKEAERLDRKQQPYDLVWEDDQRLSGKSFYLPGSLDVSDKQIDQWNKSPPPLYLWSRPDWTQKHKRIAEQHGHTKAKVFSHTEEDMLYLFEDRATQNHDVNNKQNFTSGKGKEARTDGNKNFAAKKPVQADGFPPEKLVEVAYEETKVASNRSGMHQSDQISVHDERDAHSDFPISRYNSMKAKEVSNSSRDSWKSDNTGHDVKADSNMSISPSDSRNFLHNSSNYEPPMSSRSGYTSERLRYHDNCFDHLVGENSSSLQMPTFEDSYFRSVNEYGVASVQNNIAFSTDNVGASSRMYSPDLEELNRLYAGDPTGSAYGSVSGGTGGSFYRRQNLEDYTMEGSESAQMNPVPGRELQENAGTYYGHNRDGLPQTAINTPSMDIRTQIRMYGRHMDDHTQTTMNPPANDIRAQIRMYGRHAASDHQHTSRYSSGSPDARFEQPSSLTSYGMPSSGSTGRSMIDRSIDETSYRTTVQRGPYNASDFRRDRHPDAMNFAPHKQHPYPHPGSSGGWVD