Information report for OE9A044377
Gene Details
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Functional Annotation
- Encodes an auxin receptor that mediates auxin-regulated transcription. It contains leucine-rich repeats and an F-box and interacts with ASK1, ASK2 and AtCUL1 to form SCF-TIR1, an SCF ubiquitin ligase complex. Related to yeast Grr1p and human SKP2 proteins, involved in ubiquitin-mediated processes. Required for normal response to auxin and repressed in response to flagellin. As part of the SCF complex and in the presence of auxin, TIR1 interacts with Aux/IAA transcriptional repressor proteins and mediates their degradation. Mutations in TIR1 block auxin stimulation of flavonoid synthesis.
Homologous
- Actinidia chinensis: CEY00_Acc17389, CEY00_Acc09611
- Capsicum annuum: T459_05804
- Gossypium hirsutum: Gohir.D10G022000, Gohir.A10G021200
- Manihot esculenta: MANES_16G020400
- Nicotiana attenuata: A4A49_27088
- Populus trichocarpa: POPTR_011G042400v3
- Sesamum indicum: SIN_1001355, SIN_1027020
- Solanum lycopersicum: Solyc02g079190.3
- Solanum tuberosum: PGSC0003DMG400022404
- Vitis vinifera: VIT_00s0181g00040
Gene Resources
- Pfam: PF18511 PF18791
- UniProt: A0A8S0UUS2
- EMBL: CACTIH010009073
- InterPro: IPR001611 , IPR001810 , IPR006553 , IPR032675 , IPR036047 , IPR041101 , IPR041567
- PANTHER: PTHR16134 , PTHR16134:SF148
- SUPFAM: SSF52047 , SSF81383
- Gene3D: 1.20.1280.50 , 3.80.10.10
- OrthoDB: A0A8S0UUS2
- CDD: cd22159
Sequences
CDS Sequence
- >OE9A044377
ATGCAAACGGATCCAAACCCCAAGAAATCCAAAGATTCGCCATCAAACTCAGATAGCACCGAGTCAACTCAGTCAGCCTCTCCGTTCCCAGATGATGTCCTGGGAAAAGTTCTCTCGTTTCTAAATTCGGACAAGGATAGAAGTTCAGTTTCACTGGTGTGCAAGGATTGGTACAATGCTGAGCGCTGGACAAGAACAAAACTTTTCATAGGCAATTGCTATTCGGTCTCTCCAGAGATTGTGGCCACAAGGTTTCCAAAAATCACGAGTGTCACGCTCAAAGGGAAACCTAGGTTTTCTGATTTCAATTTGGTCCCTCAAAATTGGGGGGCGGATGTTCATTATTGGCTTGTCATGTTTGCCAAAGTCTACCCCTTTCTGGAGGAATTGAGGCTCAAGAGGATGACGGTCAGCGATGAGAGCTTGGAGATCCTGGCCACGGCATTTCCTGGCTTCAGGGCGTTATCTTTGATGAGTTGTGATGGATTCAGCACAGATGGGCTCAAATCTGTTGCCACTCATTGCAGGAACTTGACTGAGCTTGACATACAGGACACCGATATAGATGACTTTAATGGTGGTTGGTTGAGTTGCTTCCCTGAGAATTTTGGTTCACTGGAAGTACTTAACTTTGCCAGCCTTGACAGTGAGGTCAATTTTGATGCCCTCGAGAGACTTGTCAGTCGGTGCAAGTCGCTAAGGGTTCTTAAGGTCAATAAGAGTATTACATTGGACCAATTACAGCGACTGCTTCTGCGGGCCCCTCAGTTGATGGAGCTTGGAACTGGTTCCTTCCAGCAAGAGCTTTTGCCTGGTCAATTTGGCGACCTTGAGAGTGCATTCAGCAATTGTAAAAATCTTCGAACTCTTTCAGGTTTATGGGAAGTCACTTCGGTCTACCTCCCTGTTCTTTATGCAGCTTGCACCAGTCTAACCTTCCTGAACCTGAGCTATGCGGCTCTTCGAAGTGTTGAATTTGGAAATCTTATTGCTTACTGCCCCAATTTGAGGCGCCTCTGGGTTCTTGATACGGTTGAAGACAAGGGGCTTGAAGCTGTTGGATCCAGCTGTCCCTTGCTTGAAGAACTCCGAGTCTTCCCTGCTGATCCTTTTGACCAGCAACTTCACCGTGGGGTGACTGAGTTGGGTTTTGTGGCTGTGTCTCGTGGATGCAGCAAACTCCACTATGTTCTCTACTTTTGCTGGCAGATGACTAATGCTGCTGTTGCCACCATTGTGCAGAACTGCCCCAATTTTACGCACTTTCGTCTTTGCATAATGAATCCAGGTCGGCCAGATTACCTCACAAATGAACCTATGGACGAGGCCTTCGGTGCAGTGGTTAAAACTTGCACTAAGCTCCAGAGGCTTTCCGTTTCAGGCCTTCTAACTGATCTGACTTTTGAGTATATTGGGAAGCATGCCAAAAACCTCGAGACTCTTTCTGTGGCTTTTGCTGGCAGCAGTGATTTAGGGATGCAGTGTGTTCTTGAAGGTTGTCCAAAGCTAAGGAAGCTTGAGATAAGAGATTGTCCATTTGGGAATGCTGCTCTTCTGTCTGGACTAGAGAAATATGAGAAAATGCGGTCATTGTGGATGTCATCCTGTAATGTGACTATAACTGCATGTCAGCAACTTGCTAGGGAGATGCCGAGGTTGAATGTTGAGGTGATGAAAGACAAGGAAAGTGATGACAGTCAAGCTGACAAAGTCTATGTCTATCGTTCAGTAGCAGGGCCAAGAAGAGATGCCCCACCTTTTGTTCTCACTCTTTGA
Protein Sequence
- >OE9A044377
MQTDPNPKKSKDSPSNSDSTESTQSASPFPDDVLGKVLSFLNSDKDRSSVSLVCKDWYNAERWTRTKLFIGNCYSVSPEIVATRFPKITSVTLKGKPRFSDFNLVPQNWGADVHYWLVMFAKVYPFLEELRLKRMTVSDESLEILATAFPGFRALSLMSCDGFSTDGLKSVATHCRNLTELDIQDTDIDDFNGGWLSCFPENFGSLEVLNFASLDSEVNFDALERLVSRCKSLRVLKVNKSITLDQLQRLLLRAPQLMELGTGSFQQELLPGQFGDLESAFSNCKNLRTLSGLWEVTSVYLPVLYAACTSLTFLNLSYAALRSVEFGNLIAYCPNLRRLWVLDTVEDKGLEAVGSSCPLLEELRVFPADPFDQQLHRGVTELGFVAVSRGCSKLHYVLYFCWQMTNAAVATIVQNCPNFTHFRLCIMNPGRPDYLTNEPMDEAFGAVVKTCTKLQRLSVSGLLTDLTFEYIGKHAKNLETLSVAFAGSSDLGMQCVLEGCPKLRKLEIRDCPFGNAALLSGLEKYEKMRSLWMSSCNVTITACQQLAREMPRLNVEVMKDKESDDSQADKVYVYRSVAGPRRDAPPFVLTL