Information report for OE9A004207
Gene Details
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Functional Annotation
- Encodes an auxin receptor that mediates auxin-regulated transcription. It contains leucine-rich repeats and an F-box and interacts with ASK1, ASK2 and AtCUL1 to form SCF-TIR1, an SCF ubiquitin ligase complex. Related to yeast Grr1p and human SKP2 proteins, involved in ubiquitin-mediated processes. Required for normal response to auxin and repressed in response to flagellin. As part of the SCF complex and in the presence of auxin, TIR1 interacts with Aux/IAA transcriptional repressor proteins and mediates their degradation. Mutations in TIR1 block auxin stimulation of flavonoid synthesis.
Homologous
- Daucus carota: DCAR_018358
- Glycine max: Glyma.03G209400
- Gossypium hirsutum: Gohir.D08G080700
- Juglans regia: Jr08_12700, Jr11_13940
- Manihot esculenta: MANES_05G067800, MANES_01G214300
- Nicotiana attenuata: A4A49_22056
- Prunus avium: Pav_sc0000848.1_g430.1.mk
- Prunus persica: PRUPE_8G253300
- Rosa chinensis: RchiOBHm_Chr6g0292661
- Sesamum indicum: SIN_1012494, SIN_1012796
- Solanum lycopersicum: Solyc09g074520.3
- Solanum tuberosum: PGSC0003DMG400011353
- Vitis vinifera: VIT_07s0104g01320
Gene Resources
- Pfam: PF18511 PF18791
- UniProt: A0A8S0RJ67
- EMBL: CACTIH010003634
- InterPro: IPR001611 , IPR001810 , IPR006553 , IPR032675 , IPR041101 , IPR041567
- PANTHER: PTHR16134 , PTHR16134:SF66
- SUPFAM: SSF52047
- Gene3D: 1.20.1280.50 , 3.80.10.10
- OrthoDB: A0A8S0RJ67
- CDD: cd22159
Sequences
CDS Sequence
- >OE9A004207
ATGGCGTACTCGTTCCCGGAGGAGGTGCTGGAGTACGTGTTTGCGTTCTTGAGCTCCCACAAGGACCGGAACGCGGTTTCACTGGTGTGCAAATCGTGGTATGAGATTGAGAGGTGGTGCCGGAGGAGGATTTTTATCGGGAACTGTTATGCGGTGAGTCCACAAATCGTGATCCGCCGGTTTCCGGAGGTGAGGGCAGTGAAGATCAAGGGGAAACCGCATTTTGCGGATTTCAACTTGGTGCCGGAGGGTTGGGGTGCGTATGTGTATCCATGGATCTCAGCCATGGTTAGATCTTACCCGTGGCTTGAAGAAATCAAGCTCAAGCGCATGGTGGTTACGGATGAGAGCTTGGAGCTTCTCTCCAAGTCGTTCAAAAATTTTAAAGTTTTGGTGCTCTCGTCGTGTGAGGGGTTCACTACTGATGGTCTTGCCTCCATTGCAGCCAATTGCAGGAACCTTAGAGAACTAGATTTGAGGGAGTGTGAAGTGGAGGACTTGAGTGGGCATTGGCTTAGCCATTTCCCAGACAACTTCACATCACTGGTGTCGCTTAACATGTCTTGTTTAGGTTCTGAGGTGAGCTTTTCTGCTCTGGAGCGTCTTGTTTCACGTTGTCCTAACCTGAGAACTCTTCGTCTGAATCGTGCGGTGCCTGTTGAGAAGCTCCCAAACCTACTTCGCCGTGCACCCCAATTGGTTGAGTTTGGTACAGGTGCCTATTCGGCTGAAAATCAAACGGATATCTTCTCAAACTTGGTAGAAGCTTTTTCAGGCTGCAAGCATCTCAAAAGCTTGTCGGGGTTTTGGGATGTGGATCCAGCTTACCTTCCAGCAATGTATTATGCGTGCACCGGAATCACTTCATTGAACTTGAGCAATGCTACTGTTCAAAGTCCAGATCTTGTTGAGCTCATTATCCAGTGTCCCAATTTGAAGTGTCTATGGGTGCTGGATTACATCGAGGATGCTGGTCTTAAGGCACTTCCCTCATATTGCAAGGATCTGCAGGAACTTAGGGTGTTTCCTTCAGATCCTTATGGTGCAGAACCAAATGTGTCTTTGACGGAACAGGGGCTTGTCACAGTTTCAGCAGGTTGCCCCAAGCTTCAGTCGGTGCTATACTTCTGCCGTCAGATGTCAAATGCAGCGTTGATTACTATTGCAAGGAATCGTCCTAACCTTATTCGCTTCCGTTTATGTATTATCGACCCTCAAGCTCCTGATTACCTAACCCTTGAACCTCTTGATACTGGCTTTGGAGCAATTGTAGAGCACTGTAAAGAGCTGCTGCGCCTTTCTATGTCTGGTCTCCTCACTGATCGAGTTTTTGAATACATTGGGACTCATGCTAAGAAACTAGAGATGCTTTCTATAGCTTTCGCTGGGGATAGTGACTTGGGCCTCCATAACGTGTTGTCTGGGTGTGAAAGCCTCCGAAAATTGGAGATCATGGACTGTCCATTTGGGGACAAGGCTCTCTTGGCCAATGCTGCAAAGCTGGAGACAATGCGATCCCTTTGGATGTCATCTTGCTCCGTCAGAAGATGCCCAAGCTCGAATGTTGAAGTTATGGACGAGAGAGGACACCCTGATTCAAGGCCAGAAACCTGTCCTGTTGAAAAACTCTATATATACAGGACAGTTGCAGGGCCAAGAGTTGATAAACCCAATTTTGTATGGACAATGGATGAAGATGCAGTGTTGAGGCTTTCTTAA
Protein Sequence
- >OE9A004207
MAYSFPEEVLEYVFAFLSSHKDRNAVSLVCKSWYEIERWCRRRIFIGNCYAVSPQIVIRRFPEVRAVKIKGKPHFADFNLVPEGWGAYVYPWISAMVRSYPWLEEIKLKRMVVTDESLELLSKSFKNFKVLVLSSCEGFTTDGLASIAANCRNLRELDLRECEVEDLSGHWLSHFPDNFTSLVSLNMSCLGSEVSFSALERLVSRCPNLRTLRLNRAVPVEKLPNLLRRAPQLVEFGTGAYSAENQTDIFSNLVEAFSGCKHLKSLSGFWDVDPAYLPAMYYACTGITSLNLSNATVQSPDLVELIIQCPNLKCLWVLDYIEDAGLKALPSYCKDLQELRVFPSDPYGAEPNVSLTEQGLVTVSAGCPKLQSVLYFCRQMSNAALITIARNRPNLIRFRLCIIDPQAPDYLTLEPLDTGFGAIVEHCKELLRLSMSGLLTDRVFEYIGTHAKKLEMLSIAFAGDSDLGLHNVLSGCESLRKLEIMDCPFGDKALLANAAKLETMRSLWMSSCSVRRCPSSNVEVMDERGHPDSRPETCPVEKLYIYRTVAGPRVDKPNFVWTMDEDAVLRLS