Information report for MANES_15G040500
Gene Details
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Functional Annotation
- Blue light receptor mediating blue-light regulated cotyledon expansion and flowering time. Positive regulator of the flowering-time gene CONSTANS. This gene possesses a light-induced CNT2 N-terminal homodimerisation domain.Involved in blue-light induced stomatal opening. Involved in triggering chromatin decondensation. An 80-residue motif (NC80) is sufficient to confer CRY2’s physiological function. It is proposed that the PHR domain and the C-terminal tail of the unphosphorylated CRY2 form a “closed” conformation to suppress the NC80 motif in the absence of light. In response to blue light, the C-terminal tail of CRY2 is phosphorylated and electrostatically repelled from the surface of the PHR domain to form an “open” conformation, resulting in derepression of the NC80 motif and signal transduction to trigger photomorphogenic responses. Cry2 phosphorylation and degradation both occur in the nucleus.
Homologous
- Arabidopsis thaliana — AT1G04400
- Oryza sativa — LOC_Os02g41550
Gene Resources
- Pfam: PF00875 PF03441 PF12546
- UniProt: A0A2C9UCX8
- EMBL: CM004401
- AlphaFoldDB: A0A2C9UCX8
- OMA: ETLIDWD
- InterPro: IPR002081 , IPR005101 , IPR006050 , IPR014134 , IPR014729 , IPR018394 , IPR036134 , IPR036155
- PANTHER: PTHR11455 , PTHR11455:SF18
- SUPFAM: SSF48173 , SSF52425
- PROSITE: PS00394 , PS00691 , PS51645
- Gene3D: 1.10.579.10 , 1.25.40.80 , 3.40.50.620
- OrthoDB: A0A2C9UCX8
- SMR: A0A2C9UCX8
- STRING: 3983.A0A2C9UCX8
Sequences
CDS Sequence
- >MANES_15G040500
ATGGGCAGCAACAAGACCATTGTTTGGTTTAGGAGGGACCTTAGAATTGAGGACAATCCTGCATTAGCTACTGCAGCCAGGGATGGTTGTGTATTTCCTGTCTTCATATGGTGTCCTCAAGAAGAAGGACAATTCTACCCAGGTCGAGTATCAAGGTGGTGGCTGAAGCAGTCTCTTGCCCACTTTGGACAGTCACTGAAATCTCTTGGGGCTGAACTCATATTGATCAAAACTCATAGTACTCTCTCTGCTCTTTTGGATTGCATAAATGCCGTTGGAGCAACAAGAGTGGTATTCAATCATCTCTATGATCCAGTATCACTTGTTCGAGATCATAACATCAAAGAAAAACTGCTGGAGCTTGGCATTACTGTGCAAAGCTATAATGGGGACTTGCTGTGTGAACCGTGGGAAATATATGATGAAAGTGGAAATGCTTTTGTGAGATTTGACTCGTTTTGGGACAAGAGCCTGCACATGCAAATGGAACCTGTTTCACATCTTCCTCCATGGCGACTACTGCCAGCTCCAGGAAAATTTGAGAAATGCTCAATTGAGGAATTGGGTCTTGAAGATGAAACAGAAAAATCTAGCAATTCCTTACTAGGAAGGGGATGGTCCCCAGGTTGGAGCAATGCTGATAAGGCACTGACTGAATTTGTTGAACAGCATCTAATTGATTATTCAAAGAATAGGCTAAAGGTTGGGGCAAACTCCAGCTCACTTTTGTCTCCATATCTTCATTTTGGAGAACTGAGCATAAGGAAAGTTTTCCAATGTGTGCGAATAAAACAGTTGCTGTGGGTGAAAGAAGAGAACTCAATAGGGAAAGAAAGCGTGACTCTGTTTCTTAGATCCATTGGGCTTAGGGAATATTCCCGATACCTTTGTTTTAACTTTCCTTTCACTCATGAGAGATCGTTGCTGAGCAACTTAAAGTATTTTCCCTGGGATGTCAACCAGGGCAATTTTAAGGCTTGGAGACAGGGACGAACCGGTTATCCCCTAGTTGATGCAGGAATGCGTGAGCTTTGGGCAACTGGTTGGATACATAATAGAATCAGAGTGATTGTTTCAAGTTTTGCTGTAAAAGTTCTGCTTCTCCCATGGAGATGGGGGATGAAGTATTTTTGGGACACACTTTTGGATGCAGACTTGGAAAGTGATATACTTGGTTGGCAATACATTTCTGGAAGCTTACCTGATGGCCATGAGCTTCAACGTTTGGATAGCCCAGAGATTCAAGGCTCAAAATTTGATCCAGAGGGCGAATATGTGAGACAGTGGCTGCCTGAGCTCGCAAGAATGCCAACTGAATGGATCCATCATCCTTGGGATGCACCTCTTTTAGTGCTTAAAGCTGCAGGGGTGGAACTGGGACAAAACTACCCAAAACCTATAATTGAATTAGATTTAGCTAGAGAACGTCTGACTGGAGCCATATTCAAGATGTGGGAAATGGAAGCGTCTGCAAGGGCTTCAGATTCAGGCGGAACAAATGAAGTTGTCGTTGATAACACTGTTGGCACTGGAAATCTGGCGATTCCAAAGGTTATGTTAAAAGAAAAAGCTCCTTGTTCAACCATTTCATCTAATGATCAGAAAGTACCAACAATTCAAAATCCTAAGTGCAATCCAGCTCACAAGAAGAGATCAAAGTACATAGAAGAGGAAAGACCAAATCGAGATAAAATGCATAAAGGTAATGGCATAAAAGGCACCTCCAGAACAGATGAAGACTTGTGCTCTACTGCTGAATCTTCAGCAACTGAGAAGCAGGCTACCAGCAGGTTTTCATTTTCTGTACCCCAGTATTGTTCATCATCAGAAAGCCAGCCCTTGCATGAGGTTGAATCATCTGATGTTAGGCAGCCATTGCAAGTGCAAATTGACAGGGAACATGTTTCAAGCAAAGATGTTGCTGCGGGAACTTAA
Protein Sequence
- >MANES_15G040500
MGSNKTIVWFRRDLRIEDNPALATAARDGCVFPVFIWCPQEEGQFYPGRVSRWWLKQSLAHFGQSLKSLGAELILIKTHSTLSALLDCINAVGATRVVFNHLYDPVSLVRDHNIKEKLLELGITVQSYNGDLLCEPWEIYDESGNAFVRFDSFWDKSLHMQMEPVSHLPPWRLLPAPGKFEKCSIEELGLEDETEKSSNSLLGRGWSPGWSNADKALTEFVEQHLIDYSKNRLKVGANSSSLLSPYLHFGELSIRKVFQCVRIKQLLWVKEENSIGKESVTLFLRSIGLREYSRYLCFNFPFTHERSLLSNLKYFPWDVNQGNFKAWRQGRTGYPLVDAGMRELWATGWIHNRIRVIVSSFAVKVLLLPWRWGMKYFWDTLLDADLESDILGWQYISGSLPDGHELQRLDSPEIQGSKFDPEGEYVRQWLPELARMPTEWIHHPWDAPLLVLKAAGVELGQNYPKPIIELDLARERLTGAIFKMWEMEASARASDSGGTNEVVVDNTVGTGNLAIPKVMLKEKAPCSTISSNDQKVPTIQNPKCNPAHKKRSKYIEEERPNRDKMHKGNGIKGTSRTDEDLCSTAESSATEKQATSRFSFSVPQYCSSSESQPLHEVESSDVRQPLQVQIDREHVSSKDVAAGT