Information report for MANES_06G114100
Gene Details
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Functional Annotation
- Relative of Early Flowering 6 (REF6) encodes a Jumonji N/C and zinc finger domain-containing protein that acts as a positive regulator of flowering in an FLC-dependent pathway. REF6 mutants have hyperacetylation of histone H4 at the FLC locus. REF6 interacts with BES1 in a Y2H assay and in vitro. REF6 may play a role in brassinoteroid signaling by affecting histone methylation in the promoters of BR-responsive genes. It is most closely related to the JHDM3 subfamily of JmjN/C proteins.
Homologous
- Arabidopsis thaliana — AT3G48430
Gene Resources
- Pfam: PF02373 PF02375
- UniProt: A0A2C9VPX7
- EMBL: CM004392
- OMA: MRFREPS
- InterPro: IPR003347 , IPR003349 , IPR013087 , IPR036236
- PANTHER: PTHR10694 , PTHR10694:SF38
- SUPFAM: SSF51197 , SSF57667
- PROSITE: PS00028 , PS50157 , PS51183 , PS51184
- Gene3D: 2.60.120.650 , 3.30.160.60
- OrthoDB: A0A2C9VPX7
- SMR: A0A2C9VPX7
- STRING: 3983.A0A2C9VPX7
Sequences
CDS Sequence
- >MANES_06G114100
ATGGCAGCTTCTGGTGGGTTGGTCTCTGAGCCAACATCACAGCAAGAGGTTTTTCAATGGCTCAAAAACCTACCGTTAGCACCAGAATACCATCCTACTCCAGCTGAATTCCAAGATCCAATTGCCTACATTTTCAAAATCGAGAAGGAAGCAGCCAAGTATGGTATCTGCAAAATCGTGCCCCCTGTCCTTGCAGCTCCCAAGAAAGCTGCAATTGCTAACCTCAACCGCTCCCTCGCCGCCCGTGCTGGTTCCTCAGCTTCCAAATCTCCACCCACATTCACTACCCGCCAGCAGCAGATCGGGTTCTGCCCCCGGAAGCCTCGCCCGGTGCAAAAGCCTGTGTGGCAGAGCGGAGAGAACTACACTTTTCAAGAATTCGAAACTAAAGCTAAATCCTTTGAGAGAAGCTATCTCAAGAAGTGCTCGAAGAAGGGAGCTCTTTCTGCTCTAGAGATCGAAACCCTATACTGGAAAGCTACTGTCGATAAGCCTTTCTCTGTTGAGTATGCCAATGACATGCCGGGTTCTGCTTTCTCACCGATAAAGACTGGAGGGAAGGAGATGGGGGAGGGGGTAACCGTGGGGGAAACGGAGTGGAACATGAGAGGAGTGTCGAGGGCAAAAGGGTCATTGTTGAGGTTTATGAAGGAGGAGATACCGGGGGTTACTTCACCAATGGTGTATGTTGCTATGATGTTTAGTTGGTTCGCTTGGCACGTGGAGGATCATGACTTGCATAGCTTGAATTACTTGCATATGGGGGCAGGGAAGACTTGGTATGGCGTGCCAAGGGAGGCTGCCGTTGCTTTTGAGGAGGTGGTCCGGGTTCATGGGTATGGAGAAGAGATAAATCCTCTTGTTACATTTGCAATTCTTGGTGAGAAGACCACAGTTATGTCACCGGAAGTATTTGTCAGTGCTGGTGTACCATGCTGCAGGTTAGTGCAAAATGCTGGGGAGTTTGTTGTCACTTTCCCAAGAGCCTATCATTCAGGGTTTAGTCATGGATTTAATTGTGGGGAGGCAGCCAATATAGCAACTCCTGAATGGTTGAGGGTTGCAAAAGATGCTGCTATTCGAAGAGCTTCGATTAATTATCCTCCTATGGTGTCTCATTTTCAGTTGCTTTATGATCTTGCACTAGAACTATGTACAAGAGTGCCGGTGAGCATCACTGCTAAACCGCGTAGTTCTAGACTAAAAGATAAGCAAAAGGTTGAAGGAGAAACACTGGTTAAAGAACTATTTATAAAGAATGTAATTCTCAATAATGGCCTGCTTCATATTCTTGGAAAAGGATCTTCAATTGTGCTTCTCCCTAGAAGTTCTTCAGACATTTCTGTTTGTTCAAATTTACGTGTTGGGTCTCAGTTAAGAGTGAGCCCTTCCCTTGGGTTATGCAGTGACAGCGTTATCTTGAAATCCTCAGAGGATTCTATTGCTGATGAAATAATGCCAGAAAGGAACAACAGAATCAATCAAGTAAAAGGCCTCCTTTCAGTGAAAGAAAAGTTTGCTTCTTTGTGTGAAAGAAATAGGCTGTCCTCATTGAATAGAAATGACAGTATGCATACTATGGTCACAGGCAACGAAAAAGGGGCTACTGTTCATGGTGATAAGTTGTCTGACCAGAGACTGTTTTCATGTGTTACTTGTGGAATTTTGAGCTTTGATTGCATTGCTGTCGTTCAACCAACAGAAGCAGCTGCTAGATACCTCATGTCTGCTGATTGTAGCTTCTTTAATGATTGGATTGTTGGTTCTGGAATAACTAATGATGGATTCCCCATTGCTGGTGGAGAGACCAATGCTTCTGAGCAGAATTCCTCTATTAAATGGATAGAGAAGAATACTGTGGATGGTTTATATGATGTCCCTGTTCAGTCTGCTAATTACCAAATTCAGGTGATTGATCAAAATAAAGTTGCTTCAAATACTGAAACACAGAGGGGCACTTCCTCTCTTAGCTTACTAGCTTTGAATTATGGAAATTCGTCAGACTCTGAGGAAGACCAGGTTGAACCAGATGTTTTGCACCATGATGATGAAATTAACTTGGCAAACCGTTCATCTGAAAATAAATATCAGCATCAAATCTCTGCTTTGCCTTCTTTCAAGCAAGAGTGCCATCATGATGAAACTGATGATCATAATCTATCTTCATCAAGGCCTGATTGTGGAGATGAAGTTACTGTTCAAACTAATGGTTGGCATGCAAAACATGGACATGGGAATAGACCAGCCAATTTCAAGGATGAAAATGATCGAGCTCTTAACTGCTCAGTGGAGTTTGAAACTGATAATCTTGCTTCTGTGGAACCAAAGGGTCTGGAGCACACATTTAGAGGTCCAATGTCAACATCACATATGACTGGAAAAGCAAAGTTTAATAGAGTGGGGGTACCAAGAGAGCATCTGGGCGCTTCATTTGCCCAAAGGTCTGATGAAGATTCTTCTCGCATGCATGTCTTTTGTCTTGAGCATGCTGTAGAAGTGGAACAGCAACTTCGTCCTATTGGGGGAGTGCATATTTTGCTTCTTTGTCATCCAGAGTATCCCAAGATAGAAGCTGAGGCAAGGTCAGTGACAGAAGAACTGGGTATTGAGTATCTCTGGAATGATATTACTTTCAGAGATGCCACCAAAGAGGACGAGGAGAATATCCAGTCAGCTCTGGATAGTGAGGAAGCAATACCAGGGAATGGGGACTGGGCTGTAAAGTTGGGCATCAATCTTTTTTACAGTGCCAATCTTAGCCGATCTTCTCTTTATAGTAAGCAGATGCCATATAATTCTGTTATATACAATGCCTATGGTCGGATTTCTCCGGCTAGCTCGCCCACTAAGTATAATGTTTATGAAAGGAAGCCTAGCAAGCAGAAAAAGGTGGTGGCAGGGAGATGGTGTGGGAAAGTTTGGATGTCAAATCAAGTCCATCCCTTCCTAACAAAACGGGATTCTGAGGAACAAGATCAAGAGCAAGAACAAGACAGAAACCTCTGTGCTTGGACAAGGCCAGATGAGAAGCTTGAGAGAAAATCAGAAAGTACCTGTAGGACTGAAACTACCTCAGCCACCAGAAAATCTGGGAGGAAGAGGAAAATTACAGTAGCAAGTGGACCAGGTAAGAAAGTCAAGTGTCTTGATACAGAAGATGCAGCTTCAGAAGATTCTCAAGAGGATGTTTCTCATAAGCAGCATACAAGGGTTTATAGTAGGAAGCAAATTAAACGTGTTGAGAGAGAAATTTCATATGATCTGTTGGAGGATGATTCTCATCAGCGGTGTGGAAGAACTCACAGAAGCAAGCAGGCTAAATCTGTTGAGAAAGAGGATGCAACGTCAGATGATTCCTTGAGATGGAACACTCATCAGCAGCACAGAAGAATTCTTAGGAGCAAACAGGACAAATCGTTTGAGAGTGAAAATGATGTTTCTTATGCTTTAGTGGACAACACTTCTCAAAAGAAACATGGCAGAATTCCTAAAACTGGAAGGAAGCAAGCCAAATATGTTGAGAGGAAAGAATTTTCAGATGATTCATTGGAAGGTGATATTCGTGATTGGCATGGAAGGGTTTCTAGAGGCACGCAAGACAAGTTTAGGAGGGAAGATGCATTTTCAGATGATTCACTAGAGGAGAGTTCTCATCGGCCACTAAGGAGGGTTCACATAAGAAAGCGGGGCACTTATTTTGAAAAGGAAGAGGCAATTTCAGATGATTCACTGGACAATAGTTCTCTGCAGCAGAAGAGGATTTCTGGAGGCAGCCAAGCAAAATTTAGGGATGATGAAGTTTCAGATGATATGTTGGAAGGAAGTACGTACCAGCAGCAAACAGGATCTTATAGGAGCAGGGAATCCAAATTTCTTGATGGGGAGGGTGCAGTTTCTGATGACCTGCTGGAGGACAATACTTGTCAGCAACACAGGAGGATATTCAGAACCAAGCAAGCCAAATTTGTGGAAAGGGAAAATGCAACTTCGGATGATTCATTGGAGGACACTATCCGGCAGCAACGCAGAGTGATTCCTAGAAGCAAAAGGTCCAAATTTATTGAGAGAGAAGATGCAATTTCAGATGATTTGCTGGAGGATGATACTAATCTGAAGCACAGGACGATACCCAGGAGCAGGAAGGCCAAATTTGCAGAGAGGGAAGATTTTTCAGTTGATCTGCAGGAGGATGATGGTCAATGGCAGCAAAGGAAGGCCCCTAGAGGCAAGCAAACCAAATTTATTGAGAGTGAGGATGTATCAGATGATCTGCAGGAAGAGGATGCTCATTGGCAGCTGCGGAAGACCTCTCGATGCAAGCAAGCTGCATCTACAGAGAGTGGAGATGTTTCAGATGATCTAGATGATGAGGGCAACACTCGTTGGCAGCCCAAGAAGACTCCTAGAATGAAGCAAGCCAAGTTTATTGAGAGGGAAGATGTTTCAGATGATCTGCACGAGGATGATAGTGGTTGGCAGCCAAGGAAGATTCCTAGAGGCAAGCAAGCCAAACTTATTGAGAGGGAAGATGCAGTTTCAGACGATTTGTTGGAGGATAATTCTAATAAGCAACACCGAAGGAATCTTAGAAGCAAGCAAAGGAAACCAGTGACCCTTCGCAAAATGAAGCGAGGGGCTGTACAGCGCGTGAAACAAGGGACTGCTAGGCTCAAAAAGAACGAGAGTCTCCAATCAATCAAACAAGGAAAGCAAACAAAGCAAGAAACTCCTCGGTTTTCAAATGCTAAATTTGAGCATAATGCAAGACAGCAGTTGGAATCAGGTGCTGAAGAGGAGCTAGAAGGTGGCCCTAGTACACGCCTTAGGAAAAGGCCATCAAAACCTTCAAAAGAGTCAGAAACCAAGCTAAAAGAGAAGCTGCAAAACAATAGGAAGAAAGTGAAGAGTGGTTCAGCTGGGAAGCCCCCAAATGGGCAGAAGAATGTGAAACATAAGGATGAGGAAGCAGAATATCAATGTGACATTGAGGGGTGCACCATGAGCTTTGGGTCAAAACAAGAGCTAGCAGTGCACAAAAGAAACATTTGTCCAGTGAAGGGATGTGGAAAGACATTCTTCTCGCACAAATACCTGGTGCAGCACCGTCGAGTCCACCTGGACGACCGCCCCCTGAAGTGCCCCTGGAAAGGTTGCAAGATGACATTCAAATGGGCATGGGCTCGGACTGAACACATAAGGGTTCACACAGGGGCTCGTCCTTATGTTTGTGGAGAAGAAGGTTGTGGGCAGACGTTCAGATTCGTGTCAGACTTCAGTCGTCACAAGCGGAAGACTGGTCATTCAGTGAAGAAAAGCAGCAAAAGGTTAATTTAA
Protein Sequence
- >MANES_06G114100
MAASGGLVSEPTSQQEVFQWLKNLPLAPEYHPTPAEFQDPIAYIFKIEKEAAKYGICKIVPPVLAAPKKAAIANLNRSLAARAGSSASKSPPTFTTRQQQIGFCPRKPRPVQKPVWQSGENYTFQEFETKAKSFERSYLKKCSKKGALSALEIETLYWKATVDKPFSVEYANDMPGSAFSPIKTGGKEMGEGVTVGETEWNMRGVSRAKGSLLRFMKEEIPGVTSPMVYVAMMFSWFAWHVEDHDLHSLNYLHMGAGKTWYGVPREAAVAFEEVVRVHGYGEEINPLVTFAILGEKTTVMSPEVFVSAGVPCCRLVQNAGEFVVTFPRAYHSGFSHGFNCGEAANIATPEWLRVAKDAAIRRASINYPPMVSHFQLLYDLALELCTRVPVSITAKPRSSRLKDKQKVEGETLVKELFIKNVILNNGLLHILGKGSSIVLLPRSSSDISVCSNLRVGSQLRVSPSLGLCSDSVILKSSEDSIADEIMPERNNRINQVKGLLSVKEKFASLCERNRLSSLNRNDSMHTMVTGNEKGATVHGDKLSDQRLFSCVTCGILSFDCIAVVQPTEAAARYLMSADCSFFNDWIVGSGITNDGFPIAGGETNASEQNSSIKWIEKNTVDGLYDVPVQSANYQIQVIDQNKVASNTETQRGTSSLSLLALNYGNSSDSEEDQVEPDVLHHDDEINLANRSSENKYQHQISALPSFKQECHHDETDDHNLSSSRPDCGDEVTVQTNGWHAKHGHGNRPANFKDENDRALNCSVEFETDNLASVEPKGLEHTFRGPMSTSHMTGKAKFNRVGVPREHLGASFAQRSDEDSSRMHVFCLEHAVEVEQQLRPIGGVHILLLCHPEYPKIEAEARSVTEELGIEYLWNDITFRDATKEDEENIQSALDSEEAIPGNGDWAVKLGINLFYSANLSRSSLYSKQMPYNSVIYNAYGRISPASSPTKYNVYERKPSKQKKVVAGRWCGKVWMSNQVHPFLTKRDSEEQDQEQEQDRNLCAWTRPDEKLERKSESTCRTETTSATRKSGRKRKITVASGPGKKVKCLDTEDAASEDSQEDVSHKQHTRVYSRKQIKRVEREISYDLLEDDSHQRCGRTHRSKQAKSVEKEDATSDDSLRWNTHQQHRRILRSKQDKSFESENDVSYALVDNTSQKKHGRIPKTGRKQAKYVERKEFSDDSLEGDIRDWHGRVSRGTQDKFRREDAFSDDSLEESSHRPLRRVHIRKRGTYFEKEEAISDDSLDNSSLQQKRISGGSQAKFRDDEVSDDMLEGSTYQQQTGSYRSRESKFLDGEGAVSDDLLEDNTCQQHRRIFRTKQAKFVERENATSDDSLEDTIRQQRRVIPRSKRSKFIEREDAISDDLLEDDTNLKHRTIPRSRKAKFAEREDFSVDLQEDDGQWQQRKAPRGKQTKFIESEDVSDDLQEEDAHWQLRKTSRCKQAASTESGDVSDDLDDEGNTRWQPKKTPRMKQAKFIEREDVSDDLHEDDSGWQPRKIPRGKQAKLIEREDAVSDDLLEDNSNKQHRRNLRSKQRKPVTLRKMKRGAVQRVKQGTARLKKNESLQSIKQGKQTKQETPRFSNAKFEHNARQQLESGAEEELEGGPSTRLRKRPSKPSKESETKLKEKLQNNRKKVKSGSAGKPPNGQKNVKHKDEEAEYQCDIEGCTMSFGSKQELAVHKRNICPVKGCGKTFFSHKYLVQHRRVHLDDRPLKCPWKGCKMTFKWAWARTEHIRVHTGARPYVCGEEGCGQTFRFVSDFSRHKRKTGHSVKKSSKRLI