Information report for g19190
Gene Details
Functional Annotation
- MADS-box protein encoded by FLOWERING LOCUS C - transcription factor that functions as a repressor of floral transition and contributes to temperature compensation of the circadian clock. Expression is downregulated during cold treatment. Vernalization, FRI and the autonomous pathway all influence the state of FLC chromatin. Both maternal and paternal alleles are reset by vernalization, but their earliest activation differs in timing and location. Histone H3 trimethylation at lysine 4 and histone acetylation are associated with active FLC expression, whereas histone deacetylation and histone H3 dimethylation at lysines 9 and 27 are involved in FLC repression. Expression is also repressed by two small RNAs (30- and 24-nt) complementary to the FLC sense strand 3? to the polyA site. The small RNAs are most likely derived from an antisense transcript of FLC. Interacts with SOC1 and FT chromatin in vivo. Member of a protein complex.
Homologous
- Arabidopsis thaliana: AT5G10140.1, AT5G10140.4
- Brassica napus: GSBRNA2T00142187001, BnFLC.A2, BnaFLC.A02, GSBRNA2T00143535001, BnaA02G0035100ZS, GSBRNA2T00135921001, BnaC02G0039100ZS, BnFLC.C2, GSBRNA2T00068991001
- Brassica oleracea: XP_013628481.1, Bo3g005470
- Brassica rapa: XP_009125323.1, Bra028599, XP_009122083.1, XP_009122081.1, Bra009055, XP_009131145.1
Gene Resources
- Pfam: PF01486 PF00319
- UniProt: D6RRE4
- EMBL: AB465585 , KC505442 , KC505443 , KC505444 , KC505445 , KC505446 , KC505447 , KC505448 , KC505449 , KC505450 , KC505451 , KC505452 , KC505453 , KC505454 , KC505455 , KC505456 , KC505457 , KC505458 , KC505459
- AlphaFoldDB: D6RRE4
- InterPro: IPR002100 , IPR002487 , IPR033896 , IPR036879 , IPR050142
- PANTHER: PTHR48019
- SUPFAM: SSF55455
- PROSITE: PS00350 , PS50066 , PS51297
- Gene3D: 3.40.1810.10
- SMR: D6RRE4
- CDD: cd00265
Sequences
gDNA Sequence
- >g19190
GACGCAATTCTCTCGCGAATAAGGTACAAAGTTTCATCAACCTTTTGTCTTAAAACAGATAATATTGACTTAAATCTCGTCTACTTGGCCAAAGAGAGAGTATTAAGTTATACAAACGCTCGCCCTTATCAGCGGAATAATTACATATCTTATTTTTTTTTTCTTCATAATTATATATGTTTTGGATTTTGATTTTAACCGCCGATTAAAGGTGGCTAATTAAGCAGCGGGAGAGTCACCGGAAGATTGTCGGAGATTTGTCCTGCAGGTGAAATCTCCATCTCAGCTTCTGCTCCCACATGATGATTCTTCTCCATCTGTACGATAATCATAGGTCAAAATCTCTAGATCTATTCACTTTCTCTTTTTGTCTTCTATCCAAGGAATATCTTTTTCATACAATCAATTAAGACTAACAACCATAAAAGCACATAAGAAGGTTATTTTCTCATAATTTGTCTGCTTTTTACGTTCAAGCTTTAAAGTTTGGAAGCATGTACCTAAGCTTTTACCTACCAGTTTATAATATCTAACCTATAACATGTAAAAAAGTAGCACTACTCCTAAACACTTTTTGGAACTGAGCCATTCGGTACCGAACAAAAACCCTAATCGGTTCATAGACTCTTTTTTGGATAAAGGGTGATTAAATTAAATTAAAATAACGACAACGTTTACACAAACACAACCTTCAAGGAAACCAATATTTAACCAAACTAGACTGAACCAGACCATATAACCTGAAAGAAAATCAAGAAATCTTAATGAATCTCTACCAGACTTAACCAGACTATAAGAGGTTCATAAATCTCAAACTGAACCAAAACCTAAATAAACCCTTAAACAAAAAAAGAAGAACCAAAACCTAGTTATGGGATGTCCAACAACCGAAAAATATATTTATATATTTTGTAAAATGATATAGCAATAATTTAATTTCTTACTCTTTATGAATTTTTTTTAAAAAATTAACTTAAAAGTATAGTGTAATCATTAATTTATACAGTTAACTTTTGTTGTTGTAACAATCCCGACTTCTCTTCTGATTTATATATTAGATAGTTTTTTCAATTAAATTACTATCTTAAAACTATCTTAAACTATTCACCTATCTTTCTAAAATCCGAATTAAAACGGAATCAAGATTTCCCCTAACTCAAACGGACCAGCCCGAATCAAATTTCTGTTCTTATTCAGTAATAATCTCACTCACCCTAATAAACCAAATCTACCAACAACCAAAATGCCCTAATTTTGATGAGAAGTATTTTCCAGAATACAATACAGGAAAAGTGCTAAGTAGTGGCTGCCAAAAAAGAAGAAGAGAAAGTGCTACCTAGTGAATATTTAAAGTGCAATGTCTATATGTATACATGGACAAGAATTGCTTACTAGTTATGCATATACTGTATATAGGAAATGTAGCTTTCGTTACCTGGCTAGCCAAAACCTGGTTCTCTTCTTTCAGCAATTTCTCCTGTTTTAAAAAGACCGACACTTTCAGCAAATACTGATCAAGTTTCTAAACCTAACAACTTCAGATTTTGGAATCCAAAACATATGCATTGGGAAGTAGTTGCAAAGATGTGTGCAAGCTCGTTAAGAAGACTTAGAGAAACAAATGACAACACACAAAAGAATATATCTGATGTGCTATAAACTTGGAAGCAAATATTTGACCTTTTCTTTGAGGTTCTCAACAAGCTTCAACATTAGTTCTGTCTGCAACAAATAAAAGCAGCACGGTTGTTTACGGCAAACAAAATTCAGAAAAGAGTAGACATTACAGAATCAACTTACCTTCTTGGCTCTAGTTACGGAGAGGGCAGTCTCAAAGTGTTCCTCCAGTTGAACAAGAGTATCGACACTCACATTATTGACATTTGATCCCACAAGCTTGCTGCATATATTCATAGTTTGACAAAAWAACCCTAATTCCTTTGTAATCAAAGGAGGAGAGCAAATATAGTCTTAGTTAGTACTAACCTTTCCACAAGTTCAAGTAGCTCATGGTGTGAACCATAGTTCAGAGCTTTTGACTGAATATCCTGCCCATGAAAAAGGGACAGAAGAAGCGGTAAAAGACAAGGGCTACGAGAATTTTGATATGCATCTGGAGCCACCACCTCATTTTATATTTAGGATCACTCGGTAAACTAATAATAGTAAATTTACTCCTTATAAAACTCCATCTGGGAAAAGATTCAAAATGTTTGTATTACCAAGGCTTTAAGATCATCAGCATGTTGTTTCCCATATCGATCAAGGATCTTGACCAGGCTGGAGAGAAGACAAAAAAAAAAATATGTTAAGATCAAAACTACTATAGCTAACCCTTGAAAAGACCACTGGAAACTATGAAACATGTATATGGCATCAGAAGAGACATTTTGGGACAACACCATAATTTTTACACATGTATATTATATATAACACCACTAATATTCTTAACATTTCAGAAAAAACAATAATCTTAGTATTCATGTTTAAGCACCGGCACATCTGAATTTGCACCCTTTTTTTTTTTTTGATATATCCGATCGGCTGATTCGGTCAGCCCCGGGGAAACGCACCGAAATGCTACTATGTGGACTCGTCGCCAACACCTAGGTGTTGGACTACCACACTGTCCAACCCCAAGTTTGAAATGCTTTTCGACTAATGTCTGGGGGTATCTAGTTAGCCTAATCACGGATACCATGTGGATTGTTTGGGCCAAAGCCCAAGCTCAAACTTCACACACAAATGTGATTTTTGTTTGTAGGGTGAATCGAACATGGGTTAGTACCTTCCAACCTTTCCCCAATTCTCCCTTACCACCTTACCAGGTGGATCGAACCTTGTTTTTTTTCTTTTTAACTTGTTCTTAGCTTTCGAAGCAATATTTAATGATATATGATCTTTTTATCTCTCAAGAAAAGAAAGGAACTCTAAAATTTACCAAGAATTGTTCAAAGTTTGATTATCCAATGCAATATGTGGGTTTACATGTATTTATTATATATATTGGCAAATTGAAAATGACTTTTTCCTCAAAGAAAAGTCATACTAAAATTTAAGGCATGCAGATGTTATCCTGTGATCTATTAATTTAATGTATATATAGCGCTGGCTTTGATTAACTTAAAGTCAAACTAGTTAAGGTACATAAGACCATCTTACGCGATTAAGACCTCTTACGCGATTTCACCGAGAAACGAAACCGGAGACGATTTCGTTGGAATTTTATTTTTATATTAATATTTTTTTTCCTAAGAATCTACCAATAATGTTGCTCTAAGAACCCTAATCATAATCGTCTATTGTCCAGATTGTTTCTATGCATTTATGTTTGTGTTTCTATGTTATAATTATTGATACAATATAAACATGTAAACGCAGCCGTAATCTTAAATGGAAACAAGCAATTGAGGCTTAAGAGAGTGTGCACACACACATCTATTTTTTGATTGTTACAGAAATCATATACTCATGAAATTATACACATATACACCTGATGAGCCACAAAGTGATGACATTGAAGTAAGCTGACGTCCAATACGTATGAGGAAGCCAAATTCCAAGTACATGCATGGACTGAGTCTTACGGAATCATATTTCTATATAATTTCCTGTAAATAATTGAAAGACACTTCCCTAAAAATAGAAAACAGTGGAAGACTGCTTGCAATTCATTTGCAACTTGTATTATTCTAATTGCAACCTCTATCAGTGCTTCCATTTTGGTTTTGATCCATACTACAACATTTAGCATCAAAACAACACATATCTTCTTTACAAATCGTGGTATCAATAGCATTATAAATCAACCTATTTACCCTCTATATTCTATCATTTACATTTCCTTATGAAATCTGATCGGGACTACGAAACAATGGTTTAGAAAAGAATTTAAAAACGCCTCTTTCATGAGTTCATTAGTAAGCTCGTGTCAAAACGGTGACATCAGCTATTTGTTTCTAGGTAATACCATATCAACATATACGAGAAAACTTTTCGAATTTTTCAATGAACCTTGAGGACAAGGTTCTTTCTAGCGATATCGCTAGTACTGATGAGCCATAACATGATCATGATGATGTGGCGGTAAGAAGATGACCATAAGTATGAGGAATCCAAAATCCAAATACATGGACCGAGTCTTAAACAAACTCATATTTCTATTTTATGTTTTCTGCAAATAATCAAAAGACTCTCCTAAGAATAGGAAGCCGGTCTTCCATATTTGTATTTCCACTTTCAATTTATTCCTCGTTTGTAGAAACGGTGAGGTTCCAATTTCCTATATTTAAACCCCAAATTCAAGCAATAAAAGTAAAGAGTTTTCTGCCATTGAAGTTACACTAACTTATATTACTAGGAAACCTATCACACCTATATATAAATATATCTTCTATAGAAGGAAGCAACTAAGACAGATAAAACTTAACTACATAATGACCTTATAGAAGACCCAACAAATTTGACAACACTTCCACTAATTCACTTTTTCTTTTTTTTTGTTAATAGGTATCAGTTCCATTGTGAAGTCAAAACTAAGAATGCAAAAATGAGTTACTGAGTAACTATTTCCACGTTCTAAAAGGCTTCTTCTATATCAAATCATAATTAAGAYCAGGAGTTCTAGTCAGGTGTCTCGACTATTCCAAGGCTGGACCTTAAMTTTCAGTATATAAGGGGTGAACAAATCCTAAGTATGYATCAAGTGAGAAACGGCCAGCGATCTTGACCAACATGGCCAAACGACTACAACCACTTGGTTAATATATTGGAGGGTTGTAGTAAACACTACACCAGCAATTTTGACAACTTATAGGATTATTCAGCATTAACCGCATATCAATCCTATAGATCTCCCGTAGGTGCATTGCATTGCATACAAATCCGAGAGATCCAATGAATTTTAATCACTCTGAAAAGAGAGACATTAATCATTAGTCAACTCTTCAAAAACTTAAGKAATCTCTAAAGCAAAGTAACAATCAAAGATGGCTTGAAACTTCACTAAACAACATCGAGCACGCATCAGATCGTATCAAACAAATCGTGAAGGACATGCAAATTATTTCCAAAGAAAATAATAAAATCCATGCAGAAAAAAAAAATTAAGAAATAYAGAGAGAGAAATGAACAAAAGTAAGAAGCTTTAGCTTCATCACGACATTGTTCTTCCTTAAATTTGGTTGTCTCATGTATCTCTCATGGTCATAGAAAAAGACACTAACAAACACAGAACCTAGAAACAACAAGAGATTCGCCGGAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGGGGAAATAAATGGAAACCCAGATAAGGAAGAGGCGTACTTATCGCCGGAGGAGAAGCTGTAGAGCTTGCCGGAAGCAGAGACGACGAGAAGAGCGACGGATGCGTCACAGAGAACAGAAAGCTGACGAGCTTTCTCGATGAGACCGTTGCGACGTTTGGAGAAGGTGACTTGTCGGCTACTTTTGTTCTCAATTCGCTTGATTTCTAGTTTTTTTCTCCCCATGGCTTCTGTCTCCGAGAGGGCTTTATTCCCTAATTTGATCCTCAGGTTGGGTTCGAAGTCGCCGGAGATACTAAGCGTTTTTTTTTTTCCTTTTTTCCTTTTATTTCTTTCTAATTTTTGTGCCCATCTACTTTTTCTT
CDS Sequence
- >g19190
ATGGGGAGAAAAAAACTAGAAATCAAGCGAATTGAGAACAAAAGTAGCCGACAAGTCACCTTCTCCAAACGTCGCAACGGTCTCATCGAGAAAGCTCGTCAGCTTTCTGTTCTCTGTGACGCATCCGTCGCTCTTCTCGTCGTCTCTGCTTCCGGCAAGCTCTACAGCTTCTCCTCCGGCGATAACCTGGTCAAGATCCTTGATCGATATGGGAAACAACATGCTGATGATCTTAAAGCCTTGGATATTCAGTCAAAAGCTCTGAACTATGGTTCACACCATGAGCTACTTGAACTTGTGGAAAGCAAGCTTGTGGGATCAAATGTCAATAATGTGAGTGTCGATACTCTTGTTCAACTGGAGGAACACTTTGAGACTGCCCTCTCCGTAACTAGAGCCAAGAAGACAGAACTAATGTTGAAGCTTGTTGAGAACCTCAAAGAAAAGGAGAAATTGCTGAAAGAAGAGAACCAGGTTTTGGCTAGCCAGATGGAGAAGAATCATCATGTGGGAGCAGAAGCTGAGATGGAGATTTCACCTGCAGGACAAATCTCCGACAATCTTCCGGTGACTCTCCCGCTGCTTAATTAG
Protein Sequence
- >g19190
MGRKKLEIKRIENKSSRQVTFSKRRNGLIEKARQLSVLCDASVALLVVSASGKLYSFSSGDNLVKILDRYGKQHADDLKALDIQSKALNYGSHHELLELVESKLVGSNVNNVSVDTLVQLEEHFETALSVTRAKKTELMLKLVENLKEKEKLLKEENQVLASQMEKNHHVGAEAEMEISPAGQISDNLPVTLPLLN