Information report for evm.TU.08.1136
Gene Details
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Functional Annotation
- Encodes EDM2 (enhanced downy mildew 2). The predicted protein bears typical features of transcriptional regulators. EDM2 contains two putative bipartite nuclear localization signals (NLS) two zinc-finger-like motifs, a Proline-rich region and a large aspartic acid-rich region. Both zinc-finger-like stretches resemble the PHD (plant homeodomain) finger motif. Mutations in EDM2 comprise RPP7 mediated resistance against Hyaloperonospora parasitica isolate Hiks1 (HpHiks1). EDM2 may function as a direct or indirect regulator of RPP7 expression.
Homologous
- Actinidia chinensis: CEY00_Acc21598, CEY00_Acc26309
- Brassica napus: BnaA02G0127700ZS
- Brassica oleracea: Bo2g038960
- Brassica rapa: Bra035572
- Citrullus lanatus: Cla97C09G182340
- Glycine max: Glyma.18G086000
- Gossypium hirsutum: Gohir.A01G085300
- Juglans regia: Jr02_25170, Jr09_15850
- Populus trichocarpa: POPTR_001G359900v3
- Prunus persica: PRUPE_4G227500, PRUPE_4G227700
- Rosa chinensis: RchiOBHm_Chr5g0041831
- Setaria viridis: SEVIR_6G126000v2, SEVIR_2G166700v2
Gene Resources
- Pfam: PF00628 PF13771 PF12678 PF13639
- UniProt: A0A803Q7Q7
- RefSeq: XP_030478780.1
- EMBL: UZAU01000701
- AlphaFoldDB: A0A803Q7Q7
- OMA: NIWIKLE
- InterPro: IPR001965 , IPR013083 , IPR022702 , IPR055198
- PANTHER: PTHR46235 , PTHR46235:SF3
- Gene3D: 3.30.40.10
- OrthoDB: A0A803Q7Q7
- CDD: cd15565 , cd15566
Sequences
CDS Sequence
- >evm.TU.08.1136
ATGGCATCGTCAGATGACGAGGATGAGGCTCTGCCACTATCTGTTGCAAATTACCATTTTGTTGATGACAAAGATGAACCTGTTTCATTTTCTGTTTTGCCAATTCAATGGAGGGAGAATGAGGAAATTGGTGGTGATAATCTACAAGTTTTCCTACATGGGACTGCTGATAATGGACTCCAGAAACTATATAAGCAAGTCATAGCATGGAAGTTCGATCTTTCCTATGTGAAGCCCGAGATATCTGTACTAACAAAGGATAATAGTTGGATCGTTCTTCAAAAGCCCAGAAAGAGTTTCGAGAAAGTCATTAAATCAATCTTGATAACAGTGAACTGTCTTCATTTTATAAGTAGAAATCCTGATACACCAGGGAAATCTTTGTGGGATCACATGTCTAAAGTTTTCAGTTCATTTGAGGTTAGGCCTTCCAAGAATGATTTGGTGGATCAAAAATCTTTGATCATTGAAGCTATGGAAAAGAATGACATCTTAGCAAAGTCCAAGTTTTTACTTGCATATCTTGATGAGAAGCCCAGAAAGAGGAAAGCACCTGATGAGGAAAGGCAAGCAACAACAACTTCAAGTTTTATAGTTGATGAAACAGAGGAAACAGAATATGCAGAAGAGGATGATTCCAATGAAGATGATGAACTGTTTGATTCTGTCTGTACTTTTTGTGATAATGGTGGTGATATTTTGTGTTGCGAAGGGAGCTGTTTAAGGTCGTTCCATGCAACTGTGGAGAGCGGTGAAGATTCTAATTGTGTTTCTCTTGGCTATACAGAGGATGAAGTAAATTTGATCCAGCAATATTTGTGCAAGAATTGCGAATATAAACAGCACCAGTGTTTTGTTTGTGGGAAATTAGGCTCCTCTGATAAATATTCAGGTGCTGAGGTGTTTCGTTGTGTTTCTGCAACTTGTGGCCGATTTTACCATCCACGCTGTGTTGCAAAATTGCTCAATCCATTCAATGGAGTTTCTGCTGAAGACCAAGAGAAAAAGATTATCAATGGGGAATCTTTCACATGTCCTATTCATAAGTGCTGTGTTTGCAAAGAAGGAGAGAATAACAAAGATCCAGATCTGCAATTTGCTGTGTGCCGGCGTTGTCCTAAGTCTTACCATAAGAAATGCTTGCCAAGGAAAATATCTTCTGAAGACATTGAAGAGGAAGGCATAGTAACAAGGGCCTGGACAGATTTACTGCCCAATCGTATTCTTATATATTGCTTAAAGCATGAGATCGATGAGGATCTTGGTACTCCAGTGAGGAACCATGTCAAGTTTCCTGGTGTTGAAGAACAAAAGAGCACTTTCAGAAAAAAGAGCACTAGTATTGGAGAAAAGAGGCAAAAGCAGACAGCAGAGTTGCTAACAGATCGGAAGAAAACTAAGACTAGAGTTGCTCCCTTGGAAAAATCCCATGAAGGAAGAACAACTCATGCTGAATCCAAACAGAGTAAGAAGTCATTTTCTGCTGTAAAAGTAGGTGGTAAGAATACTGGAAAATTACCCGTTGGATCAAGTATCCATAAGAAAGTAAAAGTAAATGATGCATCAAGAGAGGAAATGAATTCTCCCATGGCTGAGGAAAACAACTCACTGGGTGATAAGCTATACACGTTATATAATAAGAGGTCTGGATCAGTGAAGTCAAGGAAGCGGGATACATCTGATGTCGACAAGGCAGCGATAGTTAATCCTGCTACAAAAAGATCGAGCAGTGACTTACCTCCCTTAGATGCTGATAGAGAAAAGAGGTTATTAGAATTGATGAAGGATGCAGAATCAAAAATAAATATTGAAGGTATCAAACAAAAATTTAAAGCTCCCTCTACTCATGTAGCCTATAAAAATTTGGCTTCGGAAAAAGCAGCTATTACGCTGGGAAAGGTGGAGGTCTCAGTCGAGGCAATTCGAGCAGCTTTACGGAAACTTGAGGAAGGGTCCAGTATCGAAGATGCAAAAGCTGTTTGTTCATCGGAGGTTCTTGAGCGGATGTTTAAATGGAAGGATAGGCTGGGAGCATCTCTTTCACCATTTTTACATGGTATGCGCTACACTTCTTTTGGTCGGCATTTTACTAAAGTGGAGAAACTTGAAGAGATTGTCAATAAACTCCACTGGTATGTACAAGATGATGATATGATTGTGGATTTCTGCTGTGGTGCTAATGATTTCAGTGTCTTGATGAAGAAAAAGCTTGATGAGACAGGAAAAAAGTGCTCATACAAAAACTATGATTTCATAGAACCAAAGAATGATTTTTGTTTTGAGAAGAGGGACTGGATGTCTGTCAAGCCAAAGGAATTGCCAACTGGATCAAAATTGATCATGGGATTAAATCCTCCCTTTGGAGTTAGAGCATGCCTGGCAAACAAATTTATTGATAAGGCTCTTGAGTTTAACCCAAAACTTCTTATACTTATTGTTCCACAAGAAACTGAAAGGTTGGATGAAAAGGCTCAACCTTATGATTTGGTTTGGGAGGATGATCATCTGCTATCAGGAAAGTCATTTTATCTGCCTGGATCAGCTGACGTTAAGGACAAACAAATGGAACAATGGAATGTGAAGCCTCCTCTACTTTATCTATGGAGCCATCCTGATTGGTCCAACAGACATAGGAAAATAACTGAAAGTCATGTTAATCTTTTTAAACAAGAAGAGGCTGTGGTAGATGTTCATTCATTGGGTAACCATGATGATTCAGGTGAATTCCATGAGCATGCCATGGCTGACTCTGGTGATTATGGTAATATTCCTAGGCATGCACTGGGTGACCCTGGTGATTTTAGAGATATACTTGATCATGAAATGGATGACCATCAGAATTTCATGCCAACTGATGATCCTGTGGAAACTGAGAATCTGAAAGATGATGTAACTGGGGTGGTTGGAACAGGAGGACAGAAGGATTACTCCCCTTCAATCAGCAGCGATAGAGAGGATCGTGAGAATCCTGCTGGGAAGAAAGCACCCAATGAGAACACAAAGAGGCGGTTACAGACCAGAAAAAATAAGAGAAAAAGAGCAAGGGCCCAGGCTGATACTAAGAGCAGACATGGTACAGAGATGCCCAGTAGAGTATCTCCTTATACAGCCATTAATCAACGTTTTGACTCCAGCGTTCCTGGCATGCACTCCCAGTTTGGAATAGCGCATGTTGATCAGTTAGATAGACGGTACGGTAATGTTAGTGATGAGCATTCTAATTTTCCCACGAGATCAGCTACTGATTATGGGGCTAACTCTATCAGTAGACCATTAGATATGGACACTATGTACAGGAGGGAACATACTGTTCGATCACAGCTTCAGCATTACGGCCAGCAAGATCCGGAGGTCCAAGGAGGTTATTATCCTGGAGGTCAGGATTCCAGATATGGTCAGATTGGACTGCACACACCATACCCACCTACTTATGGAAATCCTGGTCCAATATCTGATCCTCTTTACAGATCAAACTCATCAGGAGCGCAGTGGTACGTACCACAATCAGACCCATTGCTTCACTCAAGAATGCACATAATGGGGTCTGAGCCACCACTGACCATTTTTGATCCTAGAGCAGCTCACTCTTATGGACTCCCGGATTTCCATTTGGGTTCTCACCTACCCTATTCACACCGTCCCCCAGGTTGGCCCAATGATTAA
Protein Sequence
- >evm.TU.08.1136
MASSDDEDEALPLSVANYHFVDDKDEPVSFSVLPIQWRENEEIGGDNLQVFLHGTADNGLQKLYKQVIAWKFDLSYVKPEISVLTKDNSWIVLQKPRKSFEKVIKSILITVNCLHFISRNPDTPGKSLWDHMSKVFSSFEVRPSKNDLVDQKSLIIEAMEKNDILAKSKFLLAYLDEKPRKRKAPDEERQATTTSSFIVDETEETEYAEEDDSNEDDELFDSVCTFCDNGGDILCCEGSCLRSFHATVESGEDSNCVSLGYTEDEVNLIQQYLCKNCEYKQHQCFVCGKLGSSDKYSGAEVFRCVSATCGRFYHPRCVAKLLNPFNGVSAEDQEKKIINGESFTCPIHKCCVCKEGENNKDPDLQFAVCRRCPKSYHKKCLPRKISSEDIEEEGIVTRAWTDLLPNRILIYCLKHEIDEDLGTPVRNHVKFPGVEEQKSTFRKKSTSIGEKRQKQTAELLTDRKKTKTRVAPLEKSHEGRTTHAESKQSKKSFSAVKVGGKNTGKLPVGSSIHKKVKVNDASREEMNSPMAEENNSLGDKLYTLYNKRSGSVKSRKRDTSDVDKAAIVNPATKRSSSDLPPLDADREKRLLELMKDAESKINIEGIKQKFKAPSTHVAYKNLASEKAAITLGKVEVSVEAIRAALRKLEEGSSIEDAKAVCSSEVLERMFKWKDRLGASLSPFLHGMRYTSFGRHFTKVEKLEEIVNKLHWYVQDDDMIVDFCCGANDFSVLMKKKLDETGKKCSYKNYDFIEPKNDFCFEKRDWMSVKPKELPTGSKLIMGLNPPFGVRACLANKFIDKALEFNPKLLILIVPQETERLDEKAQPYDLVWEDDHLLSGKSFYLPGSADVKDKQMEQWNVKPPLLYLWSHPDWSNRHRKITESHVNLFKQEEAVVDVHSLGNHDDSGEFHEHAMADSGDYGNIPRHALGDPGDFRDILDHEMDDHQNFMPTDDPVETENLKDDVTGVVGTGGQKDYSPSISSDREDRENPAGKKAPNENTKRRLQTRKNKRKRARAQADTKSRHGTEMPSRVSPYTAINQRFDSSVPGMHSQFGIAHVDQLDRRYGNVSDEHSNFPTRSATDYGANSISRPLDMDTMYRREHTVRSQLQHYGQQDPEVQGGYYPGGQDSRYGQIGLHTPYPPTYGNPGPISDPLYRSNSSGAQWYVPQSDPLLHSRMHIMGSEPPLTIFDPRAAHSYGLPDFHLGSHLPYSHRPPGWPND