Information report for A4A49_31280
Gene Details
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Functional Annotation
- Arabidopsis CULLIN4 (CUL4) forms an E3 ubiquitin ligase with the CDD complex and a common catalytic subunit RBX1 in mediating light control of development. This CUL4-based E3 ligase is essential for the repression of photomorphogenesis. The partial loss of CUL4 function resulted in a constitutive photomorphogenic phenotype with respect to morphogenesis and light-regulated gene expression. CUL4 exhibits a synergistic genetic interaction with COP10 and DET1.
Homologous
- Arabidopsis thaliana — AT5G46210
Gene Resources
- Pfam: PF00888 PF10557
- UniProt: A0A1J6IL43
- EMBL: MJEQ01037184
- AlphaFoldDB: A0A1J6IL43
- OMA: NYQEQTW
- InterPro: IPR001373 , IPR016157 , IPR016158 , IPR016159 , IPR019559 , IPR036317 , IPR036388 , IPR036390 , IPR045093
- PANTHER: PTHR11932
- SUPFAM: SSF46785 , SSF74788 , SSF75632
- PROSITE: PS01256 , PS50069
- Gene3D: 1.10.10.10 , 1.20.1310.10 , 3.30.230.130
- SMR: A0A1J6IL43
- STRING: 49451.A0A1J6IL43
Sequences
CDS Sequence
- >A4A49_31280
ATGTCTCAACCCACCACCAACCCCAAGAAGCGCTCATCATTCTTCATCTCCACAAATCCCTCCTCCTCCACTCCGACCACCGGCAGCGGCGACGTTGGCAGCGGAACCCCAGCTTATTCGTTGATGAAGAAGGCTAAGTCACAAGCTGTAAACGGCCAGCACGTTCACTTCGATAACCTTGAAGACCCTTCTGGTAACTCGGCCATGATGGAGGATTCGAACATGGACGCGCCTTCACGCGCCTCAGTTGGTGGTGGGGTTACTGCCAATTTGTCTCGCAAGAAAGCTACCCCTCCTCAGCCTGCTAAGAAACTCGTCATTAAGCTCGTCAAAGCAAAACCTACATTGCCGACAAACTTTGAAGAAAATACTTGGGCAACTCTAAAGTCAGCTATTAGTGCGATATTCTTGAAGCAGCGTAATCCGTGTGATTTAGAGGCGCTTTATCAGGCTGTGAATGACCTTTGTCTACACAAAATGGGTGGAAGTCTATATCAACGAATTGAAAAAGAGTGTGAATCACACATAGCTGCAGCTCTACGGTCTTTAGCTGGCCAAAGTGAAGATCTTGTCGTTTTCTTATCACTTGTTGAGAGGCGCTGGCAGGATTTTTGTGACAAGATGCTGATGATTCGTGGAATAGCTTTGTTTCTTGATAGAACATATGTGAAACAAACCCCAAATGTGCGTTCACTGTGGGATATGGGCTTGCAGCTTTTCCGCAAACATCTCTCTCTTGCCTCAGAAGTAGAATACAAAACTGTATTTGGCCTCCTACAGATGATTGAGTCTGAGAGATTAGGTGAGGCAGTTGAAAGGACACTGCTCAACCATCTTCTGAAGATGTTCACTGCCTTGGGGATTTACGCGGAAAGCTTCGAGAAGCCATTTCTTGAGCGTACTTCCGAGTTTTATGCTGCTGAAGGTGTCAAATACATGCAACAGTCAGATGTTCCAGATTACTTGAAGCATGTCGAGGTGAGGCTGCATGAAGAACATGAAAGGTGCTTACTCTACCTGGATGCAGGTACAAGAAAACCACTGATAGCAACTGCAGAGAGGCAACTTCTAGAGCGACACATTTCTGCCATTCTTGATAAGGGTTTCACGTTGTTGATGGATGGTAATCGTATTGAGGATCTCCAGAGGATGTATGTGCTATTTTGCAGGGTGAACGCCCTCGAATCATTGAGGCAAGCCCTTAATTCATACATACGAAGAACTGGTCAGAGCATTGTGCTAGATGAAGAGAAAGACAAAGATATGGTTTCCAGCCTCTTGGAATTTAAGGCATCCCTTGATACAATATGGGAAGAAAGCTTTTCTAAGAATGAAGCTTTTAGCAACACTATCAAGGATGCATTTGAGCATCTCATAAACATACGCCAGAATCGACCTGCCGAGCTAATTGCTAAGTTTTTGGATGAGAAGCTTCGTGCTGGGAACAAAGGTACATCAGAGGAGGAATTGGAGGGGACATTAGATAAAGTCCTGGTGTTATTCAGGTTTATACAGGGTAAGGATGTATTTGAAGCATTCTACAAGAAAGATCTTGCGAAAAGACTGTTGTTGGGAAAGAGTGCTTCAATTGATGCTGAGAAGTCCATGATTTCTAAGTTGAAGACCGAGTGTGGTAGCCAGTTCACTAACAAATTGGAGGGAATGTTCAAGGACATTGAATTGTCAAAAGAGATAAATGAATCCTTCAAGCAGTCTTCCCAAGCCAGAACTAAACTCCCAACAGGGATCGAGATGAGTGTCCATGTTTTAACGATGGGGTACTGGCCAACCTATCCGCCTATGGATGTTCGGCTTCCCCATGAACTCAATGTCTATCAGGATATTTTCAAGGAATTCTACTTGAGCAAGTATAGTGGTAGGCGTTTGATGTGGCAAAATTCATTGGGCCACTGTGTTCTGAAAGCTGAATTTCCAAAAGGTAAAAAGGAGCTCGCAGTTTCTCTATTTCAGACTGTGGCTCTAATGCTTTTTAATGATGCGGAAAAGCTTAGCTTTCAAGATATCAAGGAAGCAACTGGAATTGAGGATAAAGAGCTGAGGAGGACTTTGCAGTCTCTTGCATGTGGTAAAGTTCGTGTTCTCCAGAAGATTCCAAAAGGAAGAGATGTCGAGGATGACGATACCTTTGTGTTCAATGATCAATTTACTGCTCCGCTTTATCGCATAAAGGTAAATGCCATCCAGATGAAGGAAACAGTAGAGGAGAACACGAGCACCACTGAAAGAGTATTTCAGGACCGACAATATCAGGTTGATGCTGCAATAGTTAGGATAATGAAGACAAGAAAAGTGCTGAGTCATACCCTTTTGATAACTGAACTTTTTCAGCAGCAGCTTAAATTCCCAATAAAACCAGCTGATCTGAAGAAAAGGATTGAAAGCCTCATAGATAGGGAGTACCTGGAACGGGACAAAAACAATCCTCAAATATACAACTACCTTGCTTAA
Protein Sequence
- >A4A49_31280
MSQPTTNPKKRSSFFISTNPSSSTPTTGSGDVGSGTPAYSLMKKAKSQAVNGQHVHFDNLEDPSGNSAMMEDSNMDAPSRASVGGGVTANLSRKKATPPQPAKKLVIKLVKAKPTLPTNFEENTWATLKSAISAIFLKQRNPCDLEALYQAVNDLCLHKMGGSLYQRIEKECESHIAAALRSLAGQSEDLVVFLSLVERRWQDFCDKMLMIRGIALFLDRTYVKQTPNVRSLWDMGLQLFRKHLSLASEVEYKTVFGLLQMIESERLGEAVERTLLNHLLKMFTALGIYAESFEKPFLERTSEFYAAEGVKYMQQSDVPDYLKHVEVRLHEEHERCLLYLDAGTRKPLIATAERQLLERHISAILDKGFTLLMDGNRIEDLQRMYVLFCRVNALESLRQALNSYIRRTGQSIVLDEEKDKDMVSSLLEFKASLDTIWEESFSKNEAFSNTIKDAFEHLINIRQNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVFEAFYKKDLAKRLLLGKSASIDAEKSMISKLKTECGSQFTNKLEGMFKDIELSKEINESFKQSSQARTKLPTGIEMSVHVLTMGYWPTYPPMDVRLPHELNVYQDIFKEFYLSKYSGRRLMWQNSLGHCVLKAEFPKGKKELAVSLFQTVALMLFNDAEKLSFQDIKEATGIEDKELRRTLQSLACGKVRVLQKIPKGRDVEDDDTFVFNDQFTAPLYRIKVNAIQMKETVEENTSTTERVFQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQQLKFPIKPADLKKRIESLIDREYLERDKNNPQIYNYLA