Information report for A4A49_19906
Gene Details
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Functional Annotation
- Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.
Homologous
- Arabidopsis thaliana — AT1G08260
Gene Resources
- Pfam: PF00136 PF03104 PF08490
- UniProt: A0A1J6KI26
- EMBL: MJEQ01002105
- KEGG: nau:109212813
- OMA: MLDQCRY
- InterPro: IPR006133 , IPR006172 , IPR012337 , IPR013697 , IPR023211 , IPR029703 , IPR036397 , IPR042087 , IPR043502 , IPR054475 , IPR055191
- PANTHER: PTHR10670 , PTHR10670:SF0
- SUPFAM: SSF53098 , SSF56672
- Gene3D: 1.10.132.60 , 3.30.342.10 , 3.30.420.10 , 3.90.1600.10
- OrthoDB: A0A1J6KI26
- SMR: A0A1J6KI26
- CDD: cd05535 , cd05779
- STRING: 49451.A0A1J6KI26
Sequences
CDS Sequence
- >A4A49_19906
ATGAACGGCGGTGGAGATAATAGGCGCCGGGACTGGCGAGACACCACGAGGATTTCAAAGAAGCAGAAACTCATCCTTAGCTCCGAAGAACAACTCGAATGCAAGCTCGGATTCGATGTTTTCACCGAAGGAGATAAACGACTCGGCTGGCTTCTCACTCTGGCCTCTTCTTCATGGGAGGATCAGGAGACCCGCAAAGTGTACAGTTGCGTCGATCTTTATTTCGTTTGTCAGGATGGTTCAACATTCAAAGCGAAGTATAAATTCAGGCCATATTTTTACGTGGCAACAAAGGATAAAATGGAAATGGATGTGGAAGCATATTTGAGAAGGCGATATGAATCTCAAATTGCAGACATTGAAATTTTAGAGAAAGAGGATCTTGATCTTAAAAACCATCTATCTGGCCTACGCAGATTGTATTTAAAAATATCATTTGATACTGTCCAACAGTTGATGCACGTGAAGAGGGATCTAACACATATTGTTGAGAGAAACCAAACGAAGTTTGATACCATAGAAGCATATGAATCTATACTGACAGGGAAAAGCAAGCAGCGAAGTCAAGATTTTATAGATTATATCACTGATCTACGTGAATATGATGTCCCGTACCATGTTCGCTATGCTATTGACAACGATGTTAGATGTGGCCAGTGGTACGATGTTAGTGTATCTAGTTCTGGGGTTATGTTAGAGAAGAGGACGGATCTCTTGCAGCGAGCTGAAGTTCATGTCTGTGCCTTTGATATCGAAACAACGAAGCTTCCTCTTAAGTTTCCTGACGCCGAATATGATTCCGTAATGATGATCTCATACATGGTTGATGGCCAAGGCTATCTCATTATTAACAGAGAGTGTGTTGCGGAAGATATAGAGGATATAGAGTACACCCCAAAACCAGAGTATGAAGGGCACTTTAAAGTAACAAATGTGAAAAATGAGGAAGGGCTCCTTAGACACTGGTTTGCACATATGCAAGTGGTGAAACCCGGCATCTATGTAACATATAATGGTGACTTCTTTGATTGGCCATTTTTGGAGACAAGAGCAACTCATTTTGGCTTGAGTATGAAGGATGAGCTTGGATTTTCTTGTGACAAGAATCAAGGGGAATGCCGTGCTAAATTTGCTTGCCATCTGGATTGTTTTGCTTGGGTCAAACGTGATAGTTATCTTCCTCAAGGAAGTCAGGGTCTGAAGGCTGTTACGAAGGCCAAGTTGGGTTACGATCCTCTAGAAGTTAATCCTGAGGATATGGTTCGCTTTGCAATGGAAAAACCGCAGATGATGGCTTCATATTCTGTTTCAGATGCTGTTTCAACTTACTACTTGTATATGACTTATGTTCATCCCTTCATTTTCTCCCTTGCAACCATAATACCTATGCCGCCAGATGAAGTCTTACGCAAAGGAAGTGGGACTTTGTGTGAAATGCTTCTTATGGTCCAGGCTTATAAGGCAAATGTTATCTGTCCAAACAAGCACCAGTCTGATCCAGAGAAGTTTTATGGTAGTCAACTCCTTGAGAGTGAGACTTATATTGGTGGTCATGTGGAATGCCTAGAAAGTGGTGTATTCAGATCCGACCTTCCAACTAGTTTTAAGCTCGACCCGTCTGCCTATGAGCTATTGATCAACAACCTTGATAGAGATCTGCAGTATGCCATTGTAGTTGAGGGGAAGATGGATTTGGAATCTGTCATAAATTATGATGAAGTGAAGAATGCCGTTATGGAAAAGTTAATGAGATTGCGAGATAATCCTTTAACGGAAGAATGTCCCCTCATATATCACCTTGATGTCGCTGCAATGTATCCAAACATCATATTGACAAATAGGCTTCAGCCACCATCAATAGTTTCAGATGAGATATGCACTGCATGCGACTTTAATCGTCCTGGCAAAAAGTGTCTCCGGAAGCTTGAATGGGTTTGGCGTGGTGAAACGTACATGGCAAAGAGAAGTGATTATTACCACATAAAGAGGCAGCTCGAGTCTGAACTTGTCGAAGTAGGAGATGGTCAACGATCACAGTCTTTTCTTGATTTGCCTAAAGCAGATCAACAAGCAAAGCTGAAGGACCGCTTAAAGAAATATTGTCAAAAGGCATATAAAAGAGTCCTGGAAAAGCCGGTCACAGAACTTCGAGAAGCAGGGATCTGCATGCGAGAAAATCCTTTCTATGTTGACACCGTACGGAGTTTCCGAGATAGGCGATATGAATACAAAGGGCTTAATAAAGCTTGGAAGGGTAAGCTGTCTGAAGCAAAGGCTAGTGGAAATTCCATAAAAATTCAAGAAGCACAGGACATGGTAGTTCTGTACGATTCATTGCAGCTGGCTCATAAATGCATTTTGAATTCCTTTTATGGTTATGTCATGCGAAAGGGTGCAAGGTGGTACTCAATGGAGATGGCTGGAGTTGTTACGTATACGGGCGCAAAAATCATTCAGAATGCTCGGTTATTGGTTGAAAAAATTGGAAAACCCCTCGAATTAGACACAGATGGTATCTGGTGTGCATTACCAGGCTCTTTTCCTGAGAATTATACATTCAAGACAAAAGATCCAAAAAAGAAGCTGACGATCTCCTATCCTTGTGTTATGCTGAATGTTGATGTGGCAAGAAACAACACCAATGATCAGTACCAGACTCTGAAGGACCCCATCAATAAGACGTATACAACACACAGTGAATGCTCAATTGAGTTTGAAGTCGATGGACCATATAAGGCAATGATTCTTCCTGCTTCCAAGGAAGAAGGTATTCTGATTAAGAAGCGCTATGCAGTTTTCAACGATGATGGTACGCTTGCTGAGCTTAAAGGTTTTGAGATTAAACGTAGAGGTGAGCTAAAGCTCATCAAAGTTTTCCAGGCTGAGCTTTTTGATAAGTTCCTTCATGGATCAACCTTAGAGGAATGCTATTCAGTAGTTGCTTCAGTTGCGGATCGGTGGCTTGACCTGCTTGATAATCAAGGCAATGATATTGCGGACAGTGAGTTGCTTGATTATATATCTGAATCAAGCACAATGAGCAAATCTCTAGCCGATTATGGTGAGCAAAAGTCATGTGCGGTAACCACAGCAAAAAGGCTTGCTGATTTTCTGGGGGATGCAATGGTCAAAGATAAAGGATTGCGTTGTCAGTATATTGTTGCATGTGAGCCAAAGGGAACCCCAGTAAGTGAACGTGCTATTCCTGTTGCAATATTTGAAACTAATGCTGAGATCATGAGGTTCTATGTCAAAAAGTGGTGCAAAATATCATCAGAAGTTGGAATACGTTCCATTATTGATTGGTCTTATTACAAGCAACGGCTTAGTTCAGCAATCCAGAAGATTATCACAATTCCTGCTGCAATGCAGAAGGTTTCAAACCCTGTGCCAAGGGTGGTTCATCCTGAATGGCTGCATAAGAAGGTTCGTGAAAAAGAAGACAGATTTCGCCAACGAAAATTAAATGATATCTTCAGCTCAGTGAACAGAGATGATGCAGTGCCCAGTAAAAATTCTAAAAATCAGCAAAATATTGAAGACCTGGAAGACTTTAGACACAGCGGTAAATCGTCTATATTTGGTCCGAGGCCTGTTGTACATCGTCATGGAGTCAACAAAGATCATCCAGTGAACACTAGTGATCAAGTGGACAATCAACAACAAAGTGTTCATGCTAGCAGTCTATGCAAGATGTTACCTTCACAAGAAATTGCTGCTGTGGAAGATATTGACAGGAATGTAGATTATCATGGATGGCTACAGCAAAAAAAGAGAAAATGGAAAGAGATTCGTGAAGGGAGGAAACGCCAAAGGTTGGATACTTCAAGGACAGTAAACCATGTTAATGGCAGTACTGAATTGTCTCATCACACGGTAAACCACAAACGCCAGGGTAGGACTGGGGTTAATTCCTACTTTGAGCGACATGAATTAGCTCTCACACGAAGTCACTGGCAGATAGTTCAGCTTGAACCTACTTCACAGCATGGACAATTTTTTGCATGGGTTGTTGTGGAAGGAGCCATGCACAAAATTTCAGTAACTATCCCCAGAGTGTTTTACCTCAACTCCAAAGCTCCTATAACAGAGGAATTTCCTGGAAGACGTGTCAACAAGATTCTTCCTCATGGACGCCATAGCTACAATTTAATTGAGGTTATTATTGATGAGGATCAATTCAAGTCAGAGAGCAAAAAGCTAGCAGCTCACCTTGCTGATCCCGAAGTGGAGGGAATATATGAAACAAAGGTTCCATTGGAGTTCAGTGCTATTCTCCAGATGGGTTGTGTTTGTAAAGTTGATAAAGCAGCTAAAAAAAGGAATCCACAAGATGGTTGGAGTTTGAGCGAGCTGCATATGAAGACAACCACTGAGTGCCCGTATTTGGATCAGTCAATAACTTTCTTCTACTTATATCACAGCTTGTCCGATGGACGAGCCATTTATGTGGGATATTTTCCTTCGTCCAAGATGATACATGTTGTGGTTGTTAATCCATTTCAAAACAAGGAATTATCACCACACATTCTTGAAAGACATTATTATGAAGCTTGCCAAACATTGTCTGGTCAGCCTATCACACAAAAGGAAGGAATTAGTTTTAAGGTGGATTATGTCAAGCACATCAAGGAAGCGGAGAGGATTCTACAGAGAATAATAAATGAGCATAGGCATCATGGGCCTGCAGTTGCCATGATTGAGTGCCCGGATGCCCATTCGCTGAAGTCTGGTATACGAGCTTTGGATGATTTTCCTTGCATCAGTATCCCTTGTAATGCTCGGGATAGCCAATATCAGGCACTAGGCTGGCAAAATGTTGCAGCAAAGATTGGAATGCAGCGATGTGTTACATCCTCCCAGTGGTTAAATGAAAGGATCACTCTCTCAAGATATGCCCATGTTCCCATAGGGAATTTTGATGTTGATTGGCTCATGCATACAGCAGATATCTTCTTTTCTAGAGCACTGCGTGATCAGCAACAGGTCTTGTGGATATCTGATAATGGCATCCCTGACTTGGGAGGCGTAAATGATGAAGTATCGTCTTTTATGGATGAGGTCAATCAACCGGTTCTTACTTACCCGGGTGCATATAGAAAAGTTACTGTTGAGCTGAAGATTCATCATCTGGCTGTTGATGCTCTTCTGAAAAGCAACCAAGTAAACGAAATGGAAGGAGGCACTTTGTTTGGATTGGACCAGGACTTGAACTCTACCACGAATTTTACTAATGATAATTACTGCTTTGACGCAACGACCTCCTGTGCACCTGCATTTCGTGTACTCAAACAGTTGATCCAGAGATGCCTTACGGATGCAGTAACATCAGGAAACATATTTGCTGATGCAATGCTGCAACATTTGTATCGATGGCTCTGCAGCCCCCGGTCTAGACTGCATGACCCAGCTCTCCACAGTATGCTTCACAAGGTTATGCAAAAGATGTTTGCATTGCTTGTGGCTGAACTCCGAAAATTGGGTGCTGCTATTGTGTTTGCCAGCTTCTCAAAAATTATAATTGACACTGGAAAGTCAGATGTATCTGCAGCCAGAGCCTACTGTGATAGTGTTATTAAAACAGTACAAAATAGAGAATTGTTTGAGTGGATTGAACTTGAGCCCTTGCAGTTTTGGCACTCGTTGCTTTTCATGGATCAGTACAATTATGGGGGAATACAAGCTAGACTTAGTGATGGGCCTTTAGAAGTTAACTCAGAACCAGGTGAAGAAAGCGTGTGTGGTGAATCACAAGTCGACATTGTGTCAAGCTGGAACATTGCAGAAAATTTACCAAAGGCAACTCAGGATCATTTCATTTTGATTGTTTCGGAATTTATGTATATTCCATGGAAATTCGCACAAGAACAAGCTACACATCGAGCATCTAGTAGCGATGGTGATTTATGTACACCATCAATCACTGCTGCACTTGCTGAAACATTTGATTTGCAAATGGCGGAAAATCTAAAGAAGAAGATCCGAACTTACTTCACTGACAAACTTCTGAAAATTGTTTGTGACCCTAATCTTCAAATGAAAGTGATGAACAACTCCCAGAAGACTCAGGAGACATCAGATGCAAACTCACAATCTTATAGCCATGTCCAGAAGGGGGATCCAGCTTTAGAGTTCATTAAGCATGTCTGTGCAGTTTTGGCCCTTGACCAGAATGTGCAGCATGAAGTTCTGATCATGAGGAGAAATCTATTAAAACTTGTTCGTGTGAGGGAATTCGCTCCAGAAGCAGAATTTCACAGTCTCTCTGTGTCGTATACCCTTCCAAATGTCATTTGCAGTTACTGCAACGACTGCAGAGACCTTGACCTGTGTCGAGACAGAGCTTTGATTTCTCAGGAGTGGCGTTGTGCTGTGCCCCAATGTGGGCAACCTTATGATCGTGAAGCAATGGAAAATGCTCTTATTCAAATTGTGCGGCAGAGAGAGAGGCTATACCATCTTCAAGATCTGGTTTGCCTAAAATGCCACCAGATTAAAGCTGCACATTTAGCAGACCACTGTACTTGTGCCGGGTCATTTAGCTGCAAGGAAGGTGTCTCGGAGTTCTGCAATAAAATGCAAGTCTTCTTCAACATAGCTGTAAATCAAAAGTTTCAATTACTCCAAGAGTGCACTTCTTGGATTTTGGAAGCCAGATAA
Protein Sequence
- >A4A49_19906
MNGGGDNRRRDWRDTTRISKKQKLILSSEEQLECKLGFDVFTEGDKRLGWLLTLASSSWEDQETRKVYSCVDLYFVCQDGSTFKAKYKFRPYFYVATKDKMEMDVEAYLRRRYESQIADIEILEKEDLDLKNHLSGLRRLYLKISFDTVQQLMHVKRDLTHIVERNQTKFDTIEAYESILTGKSKQRSQDFIDYITDLREYDVPYHVRYAIDNDVRCGQWYDVSVSSSGVMLEKRTDLLQRAEVHVCAFDIETTKLPLKFPDAEYDSVMMISYMVDGQGYLIINRECVAEDIEDIEYTPKPEYEGHFKVTNVKNEEGLLRHWFAHMQVVKPGIYVTYNGDFFDWPFLETRATHFGLSMKDELGFSCDKNQGECRAKFACHLDCFAWVKRDSYLPQGSQGLKAVTKAKLGYDPLEVNPEDMVRFAMEKPQMMASYSVSDAVSTYYLYMTYVHPFIFSLATIIPMPPDEVLRKGSGTLCEMLLMVQAYKANVICPNKHQSDPEKFYGSQLLESETYIGGHVECLESGVFRSDLPTSFKLDPSAYELLINNLDRDLQYAIVVEGKMDLESVINYDEVKNAVMEKLMRLRDNPLTEECPLIYHLDVAAMYPNIILTNRLQPPSIVSDEICTACDFNRPGKKCLRKLEWVWRGETYMAKRSDYYHIKRQLESELVEVGDGQRSQSFLDLPKADQQAKLKDRLKKYCQKAYKRVLEKPVTELREAGICMRENPFYVDTVRSFRDRRYEYKGLNKAWKGKLSEAKASGNSIKIQEAQDMVVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLVEKIGKPLELDTDGIWCALPGSFPENYTFKTKDPKKKLTISYPCVMLNVDVARNNTNDQYQTLKDPINKTYTTHSECSIEFEVDGPYKAMILPASKEEGILIKKRYAVFNDDGTLAELKGFEIKRRGELKLIKVFQAELFDKFLHGSTLEECYSVVASVADRWLDLLDNQGNDIADSELLDYISESSTMSKSLADYGEQKSCAVTTAKRLADFLGDAMVKDKGLRCQYIVACEPKGTPVSERAIPVAIFETNAEIMRFYVKKWCKISSEVGIRSIIDWSYYKQRLSSAIQKIITIPAAMQKVSNPVPRVVHPEWLHKKVREKEDRFRQRKLNDIFSSVNRDDAVPSKNSKNQQNIEDLEDFRHSGKSSIFGPRPVVHRHGVNKDHPVNTSDQVDNQQQSVHASSLCKMLPSQEIAAVEDIDRNVDYHGWLQQKKRKWKEIREGRKRQRLDTSRTVNHVNGSTELSHHTVNHKRQGRTGVNSYFERHELALTRSHWQIVQLEPTSQHGQFFAWVVVEGAMHKISVTIPRVFYLNSKAPITEEFPGRRVNKILPHGRHSYNLIEVIIDEDQFKSESKKLAAHLADPEVEGIYETKVPLEFSAILQMGCVCKVDKAAKKRNPQDGWSLSELHMKTTTECPYLDQSITFFYLYHSLSDGRAIYVGYFPSSKMIHVVVVNPFQNKELSPHILERHYYEACQTLSGQPITQKEGISFKVDYVKHIKEAERILQRIINEHRHHGPAVAMIECPDAHSLKSGIRALDDFPCISIPCNARDSQYQALGWQNVAAKIGMQRCVTSSQWLNERITLSRYAHVPIGNFDVDWLMHTADIFFSRALRDQQQVLWISDNGIPDLGGVNDEVSSFMDEVNQPVLTYPGAYRKVTVELKIHHLAVDALLKSNQVNEMEGGTLFGLDQDLNSTTNFTNDNYCFDATTSCAPAFRVLKQLIQRCLTDAVTSGNIFADAMLQHLYRWLCSPRSRLHDPALHSMLHKVMQKMFALLVAELRKLGAAIVFASFSKIIIDTGKSDVSAARAYCDSVIKTVQNRELFEWIELEPLQFWHSLLFMDQYNYGGIQARLSDGPLEVNSEPGEESVCGESQVDIVSSWNIAENLPKATQDHFILIVSEFMYIPWKFAQEQATHRASSSDGDLCTPSITAALAETFDLQMAENLKKKIRTYFTDKLLKIVCDPNLQMKVMNNSQKTQETSDANSQSYSHVQKGDPALEFIKHVCAVLALDQNVQHEVLIMRRNLLKLVRVREFAPEAEFHSLSVSYTLPNVICSYCNDCRDLDLCRDRALISQEWRCAVPQCGQPYDREAMENALIQIVRQRERLYHLQDLVCLKCHQIKAAHLADHCTCAGSFSCKEGVSEFCNKMQVFFNIAVNQKFQLLQECTSWILEAR