Gene Details:

• MSU gene ID: None
• RAPdb gene ID: None
• Gene Symbol: Pikp-1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes.
• We found that any domain truncation, in either Pikp-1 or Pikp-2, prevented cell death in the presence of AVR-PikD, revealing that all domains are required for activity.
• Further, expression of individual Pikp-1 or Pikp-2 domains did not result in cell death.
• Mutations in the conserved P-loop and MHD sequence motifs in both Pikp-1 and Pikp-2 prevented cell death activation, demonstrating that these motifs are required for the function of the two partner NLRs.

Function-related keywords:

• blast-resistance ,  cell-death

Literature:

• The Pik-p resistance to Magnaporthe oryzae in rice is mediated by a pair of closely linked CC-NBS-LRR genes .  DOI:  10.1007/s00122-010-1506-3 ;  PMID:  21153625
• Characterization of rice blast resistance genes in the Pik cluster and fine mapping of the Pik-p locus .  DOI:  10.1094/PHYTO-99-8-0900 ;  PMID:  19594308
• The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation .  DOI:  10.1371/journal.pone.0238616 ;  PMID:  32931489

Related News:

Gene Resources:

• NCBI ID: ADV58352
• UniProt accessions:

Sequences: