Gene Details:

• MSU gene ID: None
• RAPdb gene ID: Os07g0142100
• Gene Symbol: OsIMA2
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Here, we report that the expressions of two IMA/FEP genes in rice, OsIMA1 and OsIMA2, are strongly induced under Fe-deficiency, positively regulated by the transcription factors IDEF1, OsbHLH058, OsbHLH059, as well as OsIMA1 and OsIMA2 themselves, and negatively regulated by HRZ ubiquitin ligases.
• Overexpression of OsIMA1 or OsIMA2 in rice conferred tolerance to Fe-deficiency and accumulation of Fe in leaves and seeds.
• Iron deficiency-inducible peptide coding genes OsIMA1 and OsIMA2 positively regulate a major pathway of iron uptake and translocation in rice.
• Knockdown of OsIMA1 or OsIMA2 caused minor effects, including repression of some Fe uptake- and translocation-related genes in OsIMA1 knockdown roots.
• Here, we reveal that OsIMA1 and OsIMA2 interact with the potential Fe sensors, OsHRZ1 (HAEMERYTHRIN MOTIF-CONTAINING REALLY INTERESTING NEW GENE (RING) AND ZINC-FINGER PROTEIN 1) and OsHRZ2.
• However, the molecular mechanism by which OsIMA1 and OsIMA2 regulate Fe homeostasis in rice is unclear.

Function-related keywords:

• transcription-factor ,  tolerance ,  iron ,  Ubiquitin ,  Fe ,  R-protein ,  homeostasis ,  Fe-homeostasis

Literature:

• Iron deficiency-inducible peptide-coding genes OsIMA1 and OsIMA2 positively regulate a major pathway of iron uptake and translocation in rice .  DOI:  10.1093/jxb/eraa546 ;  PMID:  33206982
• IRONMAN peptide interacts with OsHRZ1 and OsHRZ2 to maintain Fe homeostasis in rice .  DOI:  10.1093/jxb/erac299 ;  PMID:  35789265

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: