Gene Details:

• MSU gene ID: None
• RAPdb gene ID: Os01g0322700
• Gene Symbol: miR408 OsMIR408 OsmiR408
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• As a conserved microRNA (miRNA) family in plants, miR408 is known to be involved in different abiotic stress responses, including drought.
• Interestingly, some studies indicated a species- and/or cultivar-specific drought-responsive characteristic of miR408 in plant drought stress.
• These findings implied that miR408 could serve as a potential target for genetic manipulations to engineer perennial grass plants for improved water stress tolerance.
• Analyses of gene expression patterns and functions indicated OsMIR408 is an embryo-specific miRNA that positively regulates grain size.
• miR408 Regulates Grain Yield and Photosynthesis via a Phytocyanin Protein.
• Further studies revealed that the cleavage of OsUCL8 by miR408 affects copper homeostasis in the plant cell, which, in turn, affects the abundance of plastocyanin proteins and photosynthesis in rice.

Function-related keywords:

• drought ,  tolerance ,  abiotic-stress ,  stress ,  biotic-stress ,  drought-stress ,  stress-tolerance ,  stress-response ,  ER-stress ,  grain ,  grain-size ,  photosynthesis ,  grain-yield ,  yield ,  homeostasis ,  copper

Literature:

• Overexpression of Os-microRNA408 enhances drought tolerance in perennial ryegrass .  DOI:  10.1111/ppl.13276 ;  PMID:  33215699
• OsmiR396/growth regulating factor modulate rice grain size through direct regulation of embryo-specific miR408 .  DOI:  10.1093/plphys/kiab084 ;  PMID:  33620493
• MiR408 Regulates Grain Yield and Photosynthesis via a Phytocyanin Protein .  DOI:  10.1104/pp.17.01169 ;  PMID:  28904074
• CRISPR-Cas9 Based Genome Editing Reveals New Insights into MicroRNA Function and Regulation in Rice .  DOI:  10.3389/fpls.2017.01598 ;  PMID:  28955376

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: