Gene Details:

• MSU gene ID: LOC_Os12g38460
• RAPdb gene ID: Os12g0572800
• Gene Symbol: MEL2
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Expression analyses of several cell-cycle markers revealed that, in MEL2 mutant anthers, most germ cells failed to enter premeiotic S-phase and meiosis, and a part escaped from the defect and underwent meiosis with a significant delay or continued mitotic cycles.
• Taken together with transcriptome and gene ontology results, we propose that the rice MEL2 is involved in the translational regulation of key meiotic genes on 3’-UTRs to achieve the faithful transition of germ cells to meiosis.
• Of 249 genes that conserved the consensus in their 3’-UTR, 13 genes spatiotemporally co-expressed with MEL2 in meiotic flowers, and included several genes whose function was supposed in meiosis; such as Replication protein A and OsMADS3.

Function-related keywords:

• meiosis ,  meiotic

Literature:

• Somatic and reproductive cell development in rice anther is regulated by a putative glutaredoxin .  DOI:  10.1105/tpc.111.093740 ;  PMID:  22319054
• A novel RNA-recognition-motif protein is required for premeiotic G1/S-phase transition in rice (Oryza sativa L.) .  DOI:  10.1371/journal.pgen.1001265 ;  PMID:  21253568
• Rice MEL2, the RNA recognition motif (RRM) protein, binds in vitro to meiosis-expressed genes containing U-rich RNA consensus sequences in the 3’-UTR .  DOI:  10.1007/s11103-015-0369-z ;  PMID:  26319516

Related News:

Gene Resources:

• NCBI ID: AB522964
• UniProt accessions:

Sequences: