Gene Details:

• MSU gene ID: LOC_Os12g18410
• RAPdb gene ID: Os12g0282000
• Gene Symbol: MIR
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Growth in the MIR T-DNA knockout rice mutant (MIR) was significantly impaired compared to wild-type (WT) plants when grown under Fe-deficient or -sufficient conditions.
• We cloned and characterized a mitochondrial iron-regulated (MIR) gene in rice involved in Fe homeostasis.
• Rice-specific mitochondrial iron-regulated gene (MIR) plays an important role in iron homeostasis.
• MIR, when expressed in tobacco BY-2 cells, was localized to the mitochondria.
• These results clearly suggest that MIR is a rice-specific mitochondrial protein, recently evolved, and plays a significant role in Fe homeostasis.
• MIR transcripts were greatly increased in response to Fe deficiency in roots and shoot tissue.
• Furthermore, MIR plants accumulated more than twice the amount of Fe in shoot and root tissue compared to WT plants when grown under either Fe-sufficient or -deficient conditions.
• Despite the high accumulation of Fe in roots and shoots, MIR plants triggered the expression of Fe-deficiency-inducible genes, indicating that MIR may not be able to utilize Fe for physiological functions.

Function-related keywords:

• growth ,  iron ,  mitochondria ,  root ,  homeostasis ,  shoot

Literature:

• Rice-specific mitochondrial iron-regulated gene (MIR) plays an important role in iron homeostasis .  DOI:  10.1093/mp/ssp051 ;  PMID:  19825680

Related News:

Gene Resources:

• NCBI ID: AK103636
• UniProt accessions:

Sequences: