Gene Details:

• MSU gene ID: LOC_Os11g37620
• RAPdb gene ID: Os11g0586701
• Gene Symbol: XA10
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Here, we report the cloning and characterization of XA10, a transcription activator-like (TAL) effector-dependent R gene for resistance to bacterial blight in rice (Oryza sativa).
• Expression of XA10 induces programmed cell death in rice, Nicotiana benthamiana, and mammalian HeLa cells.
• XA10 variants that abolish programmed cell death and ER Ca(2+) depletion in N.
• We propose that XA10 is an inducible, intrinsic terminator protein that triggers programmed cell death by a conserved mechanism involving disruption of the ER and cellular Ca(2+) homeostasis.
• The rice TAL effector-dependent resistance protein XA10 triggers cell death and calcium depletion in the endoplasmic reticulum.
• The rice TAL effector-dependent disease resistance gene XA10 confers narrow-spectrum race-specific resistance to Xanthomonas oryzae pv.
• Genetic engineering of the XA10 promoter for broad-spectrum and durable resistance to Xanthomonas oryzae pv. oryzae.
• To generate broad-spectrum and durable resistance to Xoo, we developed a modified XA10 gene, designated as XA10(E5).
• The rice disease resistance (R) genes XA10 confers race-specific disease resistance to X.
• XA10 encodes an executor R protein that triggers hypersensitive response and activates disease resistance.
• Transgenic rice plants containing XA10-Ni and Xa23-Ni under the XA10 promoter provided specific disease resistance to X.
• The 19-amino acid residues at the N-terminal regions of XA10 or XA10-Ni are dispensable for their function in inducing cell death in N.

Function-related keywords:

• bacterial-blight ,  cell-death ,  homeostasis ,  blight ,  disease ,  disease-resistance ,  resistance ,  R-protein

Literature:

• The rice TAL effector-dependent resistance protein XA10 triggers cell death and calcium depletion in the endoplasmic reticulum .  DOI:  10.1105/tpc.113.119255 ;  PMID:  24488961
• Genetic engineering of the Xa10 promoter for broad-spectrum and durable resistance to Xanthomonas oryzae pv. oryzae .  DOI:  10.1111/pbi.12342 ;  PMID:  25644581
• Induction of Xa10-like Genes in Rice Cultivar Nipponbare Confers Disease Resistance to Rice Bacterial Blight .  DOI:  10.1094/MPMI-11-16-0229-R ;  PMID:  28304228
• Rapid genotyping of bacterial leaf blight resistant genes of rice using loop-mediated isothermal amplification assay .  DOI:  10.1007/s11033-020-06077-z ;  PMID:  33394228

Related News:

Gene Resources:

• NCBI ID: JX025645
• UniProt accessions:

Sequences: