Information report for LA1;LAZY1
Gene Details
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Functional Descriptions
- We show that LA1, a novel grass-specific gene, is temporally and spatially expressed, and plays a negative role in polar auxin transport (PAT).
- Here we report the cloning of the LAZY1 (LA1) gene that regulates shoot gravitropism by which the rice tiller angle is controlled.
- Loss-of-function of LA1 enhances PAT greatly and thus alters the endogenous IAA distribution in shoots, leading to the reduced gravitropism, and therefore the tiller-spreading phenotype of rice plants.
- LA1 is able to rescue the tiller angle and shoot gravitropism defects observed in LA1-SN.
- LA1 is required to regulate the expression of auxin transporters and signaling factors that control shoot gravitropism and tiller angle.
- The results show that LA1 may be involved in the nucleosome and chromatin assembly, and protein-DNA interactions to control gene expression, shoot gravitropism, and tiller angle.
- Our results provide new insight into the mechanisms whereby LA1 controls shoot gravitropism and tiller angle in rice.
Functional Keywords
- auxin , tiller , iaa , shoot , tiller-angle , shoot-gravitropism , auxin-transport
Literature and News
- LAZY1 controls rice shoot gravitropism through regulating polar auxin transport . DOI: 10.1038/cr.2007.38 ; PMID: 17468779
- Over-expression of OsPIN2 leads to increased tiller numbers, angle and shorter plant height through suppression of OsLAZY1 . DOI: 10.1111/j.1467-7652.2011.00637.x ; PMID: 21777365
- Identification of the gravitropism-related rice gene LAZY1 and elucidation of LAZY1-dependent and -independent gravity signaling pathways . DOI: 10.1093/pcp/pcm042 ; PMID: 17412736
- Loose Plant Architecture1, an INDETERMINATE DOMAIN protein involved in shoot gravitropism, regulates plant architecture in rice . DOI: 10.1104/pp.112.208496 ; PMID: 23124325
- LAZY Genes Mediate the Effects of Gravity on Auxin Gradients and Plant Architecture . DOI: 10.1104/pp.17.00942 ; PMID: 28821594
- LAZY1 Controls Tiller Angle and Shoot Gravitropism by Regulating the Expression of Auxin Transporters and Signaling Factors in Rice . DOI: 10.1093/pcp/pcaa131 ; PMID: 33067639
Gene Resources
- UniProt: Q2R435
- EMBL: AK067664, AP008217, AP014967
- AlphaFoldDB: Q2R435
- EnsemblPlants: Os11t0490600-01
- Gramene: Os11t0490600-01
- KEGG: dosa:Os11g0490600
- Orthologous matrix: CTCLTGQ
- InterPro: IPR038928
- PANTHER: PTHR34959, PTHR34959:SF3
- OrthoDB: Q2R435
- SWISS-MODEL: Q2R435
- eggNOG: ENOG502QRWV
Sequences
cDNA Sequence
- >LOC_Os11g29840.1
ATCTTAGCACGCTAAACCGGCTTCCAAGATGAAGCTCTTAGGTTGGATGCATCGAAAGCTACGGAGTAATAATGACGTGTTCAAAGAGTTCAACACCGGAGGAGGTGGGGCCTGCAACTGCATCACCGGGCTTGCCTCGCCTGACCACGACAACGACTACTTCTCCGGCGACGACGCCGCCCACGCCTCGCCGCCGGTCACCGCCGGCGACCTCTTCACCTTCGGCGGCAGCGGCCTTCTCACCATCGGCACGCTAGGCATCGCCGCCGTCGCCATTCCCAGCGGCGGCGACGACGACGACTACGACATCGACTTCGAGGTGGACGCCACCAGCGACGACGACGGCGGCTTCACCGTCGAGGACGACGACGCCGACGTCGGCGGCGCCGTCACGCCCACCTTCACCTTCCCCGCGGCGACGGCGGCGGAGGCGGTCGTCGCCACCGTGGAGAAGGCAGTGGCCGCGGTGGAGGCGATCGCGGAGAAGGACGACGACACCACCACGGAGGACGACCTGATGGTGGTGAGCGCCGAGCTGGAGAAGGTGCTCGGCGGCGTCGACGTGGCGTCGGCGCGGGTGAGCTTCGCCATGGGCGGTGGCGTCGACTGCCCGCTCCAGGGCTTCCTGTTCGGCTCCCCGGTGAGCGACGTCGAGTCGCGCCCGGAGTACCTGCAGGCGCCGCGGGACTCGTCCGGCTCCTGCGGCGGCGGCGGGCGGCGCACCTCGCTCGGCGAGCTGTTCATGCGCACCCGCTTCGCCGACGAGAAGGTGGCGCTCGTCGCCGTCGCCGAGGGCGAGGACGGCGTCGCCGGCGACGACGGCGCTGCTGCTGCCGGCGTCGGCGGAGACAGAGCGGGGAAAGGCGGCGGCTACAAGACGATGAAGAAGAGGAAGGTGAAGGACGAGAAAGGCGGCGGCGGCGCCGCCGGCGGTGGAATGCCGGCGACGGTGACGAAGAGCAAGTTTCAGAAGATCCTTCAAATCTTCCACAGGAAAGTCTACCCCGAGAACACACTCCTCACAAGGAATCTGACCAAGAAGAGCCGCAACCGCGGCGCCACCGATAATGGCGGTGGCGCCGTGGCCACCGGAGACCCCGACGGGCCTCTGGCCTCGCCGGTGCTCCGGTGCCGGAAGGACCATCCCATGAGGGGCTTCGGCTGCTGCACCAATGGCGCCTTCGGTGCATCGTCACCGGGAGGCAACGCCGAGATGAACGGCAACAAGAGCGGCCACTGGATCAAGACTGATGCCGACTACTTGGTGCTGGAATTATAATGGGGAAAAGAAGAGGAGCTATTTGTTTCATCAAGAATTAAAGCTTGAATAGTGAGCATCTCATATATATGAATATGTGCTTGCTGTTACAATATAATCTCTATCTGTTTGGTATAGAAGGGCTTGAATGTGCTGTATATGTCACTATATATTGGGGGGGAGAGGATTACTATGAGATCAACTCATAAGTGTGTGGTGTTTATATACATTGCTCTGTGAATGTATGACAGAGATCAGAACTTAATGTATTGTATGCTTTCTTGATGTGATTGGTGTTTATGAGCCTAGCTGATGGCAATATTGTGTGTGGGTCCACCCCT
CDS Sequence
- >LOC_Os11g29840.1
ATGAAGCTCTTAGGTTGGATGCATCGAAAGCTACGGAGTAATAATGACGTGTTCAAAGAGTTCAACACCGGAGGAGGTGGGGCCTGCAACTGCATCACCGGGCTTGCCTCGCCTGACCACGACAACGACTACTTCTCCGGCGACGACGCCGCCCACGCCTCGCCGCCGGTCACCGCCGGCGACCTCTTCACCTTCGGCGGCAGCGGCCTTCTCACCATCGGCACGCTAGGCATCGCCGCCGTCGCCATTCCCAGCGGCGGCGACGACGACGACTACGACATCGACTTCGAGGTGGACGCCACCAGCGACGACGACGGCGGCTTCACCGTCGAGGACGACGACGCCGACGTCGGCGGCGCCGTCACGCCCACCTTCACCTTCCCCGCGGCGACGGCGGCGGAGGCGGTCGTCGCCACCGTGGAGAAGGCAGTGGCCGCGGTGGAGGCGATCGCGGAGAAGGACGACGACACCACCACGGAGGACGACCTGATGGTGGTGAGCGCCGAGCTGGAGAAGGTGCTCGGCGGCGTCGACGTGGCGTCGGCGCGGGTGAGCTTCGCCATGGGCGGTGGCGTCGACTGCCCGCTCCAGGGCTTCCTGTTCGGCTCCCCGGTGAGCGACGTCGAGTCGCGCCCGGAGTACCTGCAGGCGCCGCGGGACTCGTCCGGCTCCTGCGGCGGCGGCGGGCGGCGCACCTCGCTCGGCGAGCTGTTCATGCGCACCCGCTTCGCCGACGAGAAGGTGGCGCTCGTCGCCGTCGCCGAGGGCGAGGACGGCGTCGCCGGCGACGACGGCGCTGCTGCTGCCGGCGTCGGCGGAGACAGAGCGGGGAAAGGCGGCGGCTACAAGACGATGAAGAAGAGGAAGGTGAAGGACGAGAAAGGCGGCGGCGGCGCCGCCGGCGGTGGAATGCCGGCGACGGTGACGAAGAGCAAGTTTCAGAAGATCCTTCAAATCTTCCACAGGAAAGTCTACCCCGAGAACACACTCCTCACAAGGAATCTGACCAAGAAGAGCCGCAACCGCGGCGCCACCGATAATGGCGGTGGCGCCGTGGCCACCGGAGACCCCGACGGGCCTCTGGCCTCGCCGGTGCTCCGGTGCCGGAAGGACCATCCCATGAGGGGCTTCGGCTGCTGCACCAATGGCGCCTTCGGTGCATCGTCACCGGGAGGCAACGCCGAGATGAACGGCAACAAGAGCGGCCACTGGATCAAGACTGATGCCGACTACTTGGTGCTGGAATTATAA
Protein Sequence
- >LOC_Os11g29840.1
MKLLGWMHRKLRSNNDVFKEFNTGGGGACNCITGLASPDHDNDYFSGDDAAHASPPVTAGDLFTFGGSGLLTIGTLGIAAVAIPSGGDDDDYDIDFEVDATSDDDGGFTVEDDDADVGGAVTPTFTFPAATAAEAVVATVEKAVAAVEAIAEKDDDTTTEDDLMVVSAELEKVLGGVDVASARVSFAMGGGVDCPLQGFLFGSPVSDVESRPEYLQAPRDSSGSCGGGGRRTSLGELFMRTRFADEKVALVAVAEGEDGVAGDDGAAAAGVGGDRAGKGGGYKTMKKRKVKDEKGGGGAAGGGMPATVTKSKFQKILQIFHRKVYPENTLLTRNLTKKSRNRGATDNGGGAVATGDPDGPLASPVLRCRKDHPMRGFGCCTNGAFGASSPGGNAEMNGNKSGHWIKTDADYLVLEL*