Gene Details:

• MSU gene ID: LOC_Os10g42430
• RAPdb gene ID: Os10g0575000
• Gene Symbol: OsMYC2
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• OsJAZ1 also interacts with OsMYC2, a transcription factor in the JA signalling pathway, and represses OsMYC2’s role in activating OsMADS1, an E-class gene crucial to the spikelet development.
• Overexpression of OsMYC2 Results in the Up-Regulation of Early JA-Rresponsive Genes and Bacterial Blight Resistance in Rice.
• Overall, we conclude that OsMYC2 acts as a positive regulator of early JA signals in the JA-induced resistance against Xoo in rice.
• The up-regulation of OsMYC2 in response to JA was regulated by OsJAZ8.
• Transgenic rice plants overexpressing OsMYC2 exhibited a JA-hypersensitive phenotype and were more resistant to Xoo.
• Our results indicate that JA signalling via OsMYC2 is reinforced by OsMYL1 and OsMYL2, resulting in the inductive production of sakuranetin during defence responses in rice.
• Furthermore, a substantial change was noted in the expression of distinct types of transcription factors, such as MYB-type factors, likely depicting the importance of OsMYC2 in not only defence responses but also other morphogenetic events.
• OsMYC2 mediates numerous defence-related transcriptional changes via jasmonic acid signalling in rice.
• The jasmonic acid (JA)-responsive transcription factor OsMYC2 acts as a positive regulator of leaf senescence by direct regulation of some senescence-associated genes in rice.
• Here, we report that OsMYC2 plays an important role in leaf senescence under dark-induced senescence (DIS) conditions.
• Overexpression of OsMYC2 significantly promoted leaf senescence, indicated by reduction of chlorophyll content under DIS conditions in rice.
• These results suggest that OsMYC2 acts as a positive regulator of leaf senescence by direct- or indirect-regulation of SAGs in rice.
• In agreement with AtMYC2 function, OsMYC2 over-expression and RNAi lines showed enhanced and suppressed seedling growth compared to WT plants respectively under blue light, and showed little effect under white light or dark.
• However, the role of OsMYC2 in seedling development under ABA, dark or light of specific wavelengths was not known.
• However, in contrast to AtMYC2 function, OsMYC2 influences seedling development under red light and show no effect in ABA-mediated seed germination.
• Moreover, the enhancement of RSV resistance conferred by BR is impaired in OsMYC2 (a key positive regulator of JA response) knockout plants, suggesting that BR-mediated RSV resistance requires active JA pathway.
• OsGSK2 physically interacts with OsMYC2, resulting in the degradation of OsMYC2 by phosphorylation and reduces JA-mediated defense to facilitate virus infection.
• OsPHR2 modulates phosphate starvation-induced OsMYC2 signaling and resistance to Xanthomonas oryzae pv. oryzae.
• Here, we report that Pi starvation in rice activates the OsMYC2 signaling and enhances resistance to Xanthomonas oryzae pv.
• Molecular analyses and infection studies using OsPHR2-Ov1 and phr2 mutants further demonstrated that OsPHR2 enhances antibacterial resistance via transcriptional regulation of OsMYC2 expression, indicating a positive role of OsPHR2-OsMYC2 crosstalk in modulating the OsMYC2 signaling and Xoo infection.
• Genetic analysis and infection assays using myc2 mutants revealed that Pi starvation-induced OsMYC2 signaling activation and consequent Xoo resistance depends on the regulation of OsMYC2.

Function-related keywords:

• transcription-factor ,  JA-signalling ,  resistance ,  xoo ,  ja ,  blight ,  resistant ,  JA ,  bacterial-blight ,  defence ,  defence-response ,  jasmonic ,  jasmonic-acid ,  leaf ,  leaf-senescence ,  senescence ,  growth ,  seedling ,  development ,  seed ,  seed-germination ,  defense ,  BR ,  RSV ,  phosphate ,  Pi ,  pi ,  phosphate-starvation

Literature:

• Jasmonic acid regulates spikelet development in rice .  DOI:  10.1038/ncomms4476 ;  PMID:  24647160
• Overexpression of OsMYC2 Results in the Up-Regulation of Early JA-Rresponsive Genes and Bacterial Blight Resistance in Rice .  DOI:  10.1093/pcp/pcw101 ;  PMID:  27335352
• OsMYC2, an essential factor for JA-inductive sakuranetin production in rice, interacts with MYC2-like proteins that enhance its transactivation ability .  DOI:  10.1038/srep40175 ;  PMID:  28067270
• OsMYC2 mediates numerous defence-related transcriptional changes via jasmonic acid signalling in rice .  DOI:  10.1016/j.bbrc.2017.03.125 ;  PMID:  28347822
• Identification of OsMYC2-regulated senescence-associated genes in rice .  DOI:  10.1007/s00425-017-2697-5 ;  PMID:  28424874
• Rice MYC2 (OsMYC2) modulates light-dependent seedling phenotype, disease defence but not ABA signalling .  DOI:  10.1007/s12038-017-9703-8 ;  PMID:  29358563
• OsJAZ13 Negatively Regulates Jasmonate Signaling and Activates Hypersensitive Cell Death Response in Rice .  DOI:  10.3390/ijms21124379 ;  PMID:  32575555
• Rice stripe virus suppresses jasmonic acid-mediated resistance by hijacking brassinosteroid signaling pathway in rice .  DOI:  10.1371/journal.ppat.1008801 ;  PMID:  32866183
• Magnaporthe oryzae systemic defense trigger 1 (MoSDT1)-mediated metabolites regulate defense response in Rice .  DOI:  10.1186/s12870-020-02821-6 ;  PMID:  33430779
• OsPHR2 modulates phosphate starvation-induced OsMYC2 signalling and resistance to Xanthomonas oryzae pv. oryzae .  DOI:  10.1111/pce.14078 ;  PMID:  33938007
• Rice MEDIATOR25, OsMED25, is an essential subunit for jasmonate-mediated root development and OsMYC2-mediated leaf senescence .  DOI:  10.1016/j.plantsci.2021.110853 ;  PMID:  33775361
• Warm temperature compromises JA-regulated basal resistance to enhance Magnaporthe oryzae infection in rice .  DOI:  10.1016/j.molp.2022.02.014 ;  PMID:  35217224

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: