Gene Details:
- MSU gene ID: LOC_Os10g34430
- RAPdb gene ID: Os10g0485600
- Gene Symbol: OsDCL3b
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Here we reported that knockdown of OsDCL3b led to reduced pollen fertility, seed setting rate, and decreased grain yield but increased grain quality in rice.
- In rice, the biochemical function of OsDCL3b is known to process 24-nucleotide panicle phased small RNAs, however, its phenotypic functions are unclear.
- OsDCL3b affects grain yield and quality in rice.
- We reported that knockdown of OsDCL3b decreased grain yield but increased grain quality in rice, which is helpful for molecular breeding in crops.
- Thus, our results show that knockdown of OsDCL3b will affect the biogenesis of small RNAs, which is involved in regulating the transcription of mRNA genes, and consequently influence the grain yield and quality in rice.
Function-related keywords:
- pollen , panicle , grain , seed , grain-yield , yield , breeding , quality , grain-quality
Literature:
- Identification of precursor transcripts for 6 novel miRNAs expands the diversity on the genomic organisation and expression of miRNA genes in rice . DOI: 10.1186/1471-2229-8-123 ; PMID: 19055717
- Roles of DCL4 and DCL3b in rice phased small RNA biogenesis . DOI: 10.1111/j.1365-313X.2011.04805.x ; PMID: 21973320
- Genome-wide identification, organization and phylogenetic analysis of Dicer-like, Argonaute and RNA-dependent RNA Polymerase gene families and their expression analysis during reproductive development and stress in rice . DOI: 10.1186/1471-2164-9-451 ; PMID: 18826656
- OsDCL3b affects grain yield and quality in rice . DOI: 10.1007/s11103-018-0806-x ; PMID: 30652247
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os10g34430.1
ATGGCCGACGACGAGGCTGCCGTCCTCCCGCCCCCGCCTCCGCTGCCGCCGCCTTGCCGCCCCCACAGGCAGCTCCGCCCGAGGGGGTCTCGACCGACTGCTGATACCACCCCTCGCACTAGCCAGTTGGTCAGTGCAGCTTAGCTGATGTTGGCTGCTCTCCTCGTTGGCGCCGCCTGCGTGCGTGCGTGCGTGCAGGTACCAGGTGGAGGTGTTCGAGGCGGCGCTGCGGGGGAACACCATCGCGGTGCTCGACACGGGGTCCGGGAAGACCATGGTCGCCGTCATGCTCGCGCGCGAGCACGCACGCCGGGTGCGCGCCGGGGAGGCGCCGCGGCGGATCGTGGTGTTCCTCGCGCCCACCGTGCACCTCGTCCATCAGCAATTCGAGGTGATTCGTGAGTACACTGACCTCGACGTGATGATGTGCTCTGGAGCATCGCGGGTTGGCGAATGGGGCGCCGATCATTGGAAGGAGGAAGTTGGGAGAAATGAGATCGTTGTTATGACGCCACAGATACTGTTGGATGCTCTGCGGCATGCTTTTCTGACAATGAGTGCAGTGAGCTTGCTAATATTTGATGAATGTCATCGTGCTTGTGGAAGCCATCCATATGCACGAATAATGAAGGAATTTTATTTTGGGTCTCAGTGGAGGCCAGATGTATTTGGAATGACAGCCTCCCCCGTTGCTACTAAAGGTGCTTCCACACTACACAATTGTGAAGCACACATTTCTCAACTAGAACTAACCTTGGATGCCAAGATATACATCGTAGAAGATCGAAATGAGCTTGAGAGCTTTTCCCCTCCTACAACAATTGTGAACAAATACTATGATGCTTACATGGTTGATTTTGATAATCTGAAATCAAAGCTTCAGATATTTTCTGATGAGTTTGATTCTTTGTTGGTTGGTCTTCAAGAATCGCCATCTAATAAATTTAAAGACACCGATAATATCCTAGAGACTTCAAGAAAGAGCTTGTCCAGATACCATGGGAAAATATTGTACAGCCTAAACGATCTTGGTCCAATTATCACCTCTGAGGTAGTCAAAATACATATTGAAAGCGTTAAGCCATTATGTGATTCTGAAGACTGCATTTTTTCTAAAGCTAGCTTGTGCTTACATATGTCTTATTTTAAAGAAGCTTTAAGTCTAATAGAGGAAATTCTTCCACAAGGATATGGTGAACTAATGAAATCAGAATCTGGTTCTGAGGAATTAACTAAAAGGGGATACATTTCTTCAAAAGTGAATACGCTAATCAACATCTTCAAATCGTTTGGGTCATCAAATGAAGTGCTTTGCCTAATTTTCGTAGACAGAATTATAACAGCTAAAGCCGTCGAAAGGTTTATGAGAGGAATTGTTAACTTCTCTTGTTTTTCAATTTCTTACTTGACTGGAGGGAGTACATCAAAAGATGCTCTGAGTCCAGCAGTTCAGAGATTTACTTTGGATTTGTTCCGAGCTGGAAAGGTGAACTTGCTTTTTACAACAGATGTGACTGAAGAGGGCGTCGATGTACCTAACTGTTCTTGTGTGATACGCTTCGACCTACCCAGAACTGTTTGTAGCTATGTCCAATCTCGTGGTCGTGCTAGAAGGAACAACTCGGAATTTATTCTTATGATTGAGAGGGGAAACTTGCAGCAGCAAGAACACATATTTCGTATGATACAGACTGGTTACTATGTTAAAAACTGTGCACTCTATAGACACCCCAATGCTTTATCCTATGACTTGTCTATCCAAGGGATGTACACCTACCAAGTTCAGTCAACTGGAGCAACTATAACCGCAGATTGCTGTGTCAACCTAATTCGTAAATACTGTGAGAAGCTTCCTAAAGATAGGTATTTCATGCCAAAGCCTTCCTTTGAGGTGACCATTGAAGATGGATTATTCAAATGCACATTGACGCTACCTCGAAATGCAGCATTTCAAAGTATAGTTGGCCCTTTAAGCAGTTCAAGTAATTTATCCAAGCAGCTTGTATCCCTAGAGGCCTGCAAGAAATTGCATCAACTGGGAGAACTTAATGATCATCTTGTACCTTTGACTGAAGAACCTATGGATACAGATTTCACTACAGCAGATGAAAAATGCATATCTGGACCAGGAACAACTAAAAGGAAGGAGCTTCATGGTACTACATGTGTTCTTGCTTTATCAGGAACTTGGATTCATGACAGTGAAAATATTACACTGAATACTTACAGAATTGATTTTCTTTGTGACCAAGAGGGTGAAAACTATGCTGGGTTTGTTCTCTTAATGGAACCAGAACTTGATGATGATGTGGCACCCTCAAAAATGGATCTGTTCCTGATCCCTAATAAAATGGTCTACACCACTGTAACTCCTCGCGGAAAAGTTCAACTAAACAAAAAGCAGTTAGGTAAAGGGAAATTGTTCCAAGAATTCTTTTTCAATGGAATCTTTGGTAGATTATTTCATGGTTCTCGAAAAAGTGGAGCACAAAGGGATTTTATTTTCAAAAAGGGTCATGAAATACAGTGGAACACGGAAAGCATGTACTTGCTTTTACCTTTGAGGGATTCTTCATATATCCAGGATGACCTAAGCATACACTGGGAAGCAATTGAATCTTGTGCTGGTGCAGTTGAGCAGTTGTGGAGTTCGTATCAAGGAGATGAAAATGTCATTCCTGTAAATTGTATTCCACAAAAAAGAAGAGGGGGCCAAGAAGAAATTATTCATCTGGCCAATAAGTCTCTTCATTGTTCCAGCATCAAAGATTCAGTCGTGCTATCACTGCATACAGGAAGGATATACACTGTTCTTGATTTGATCTTAGACACAACTGCAGAGGACTCGTTTGATGAGATGTGTAAGGGGAAAGCCTCACCTTTTACTTCATTTGTGGACTATTACCATCAAAAGTATGGTATTATTATTCAACATCCAGAACAACCACTATTGCTGTTAAAGCAAAGCCACAATGCACACAATCTTCTCTTTTCAAAATTGAAGTATCTAGATGGCTCCACTGGCAAACCTCTGCTCATGGAAAAAGAACAAATTCATGCTCGGGTTCCACCTGAACTACTTATCCATCTCGATGTAACAACTGATATTCTGAAGTCATTTTATTTACTCCCTTCTGTAATACATCGGCTTCAGTCACTTATGCTAGCCAGCCAGCTTCGCAGAGAAATTGGTTACAATCAACACATACCAGTCACTTTGATTTTGGAAGCTATAACAACTTTAAGATGCTGTGAGACATTTTCTCTGGAGCGTTTAGAGCTGTTAGGAGACTCCGTGCTAAAGTATGTGGTAGGATGTGACCTTTTCCTAAGGTATCCTATGAAACATGAAGGTCAGCTCTCTGATATGAGATCCAAGGCTGTCTGCAATGCTACACTTCATAAACATGGAATATGGCGGTCGTTGCAGGGTTATGTACGTGATAATGCTTTTGACCCACGGCGTTGGGTTGCTCCTGGACAGATATCGTTGCGCCCTTTTCCTTGTAACTGTGGAATCGAGACTGCATTTGTTCCTTCTCATAGAAGGTATATCCGAGATGACCCATCTTTTTTTGTGGGAAAACCATGTGACAGAGGTCATAGGTGGATGTGCTCAAAAACAATATCTGATTGTGTTGAAGCACTGGTTGGAGCATATTATGTTGGTGGTGGCATTGCTGCTGCACTTTGGGTTATGAGGTGGTTTGGAATCGATATCAAATGTGATATGAAGCTATTGCAGGAAGTGAAGTTCAATGCATCTCATTTATGCTCCTTATCAAAAATAAATGACATTGAGGAACTGGAAGCAAAACTGAAGTACAACTTCTCAGTCAAGGGCCTTCTTTTGGAAGCCATAACTCATCCATCTCTGCAGGAATTAGGTGTTGATTACTGTTACCAGCGTCTTGAATTTCTTGGTGATTCTGTGCTGGATCTACTTCTTACACGTCATCTCTATGCTACTCATACTGATGTTGATCCTGGAGAATTAACGGATTTACGCTCCGCTTTGGTTAGTAATGAGAATTTTGCACAAGCAGTTGTAAGAAACAACATTCACAGTCATCTACAACATGGATCCGGAATACTTTTGGAGCAAATTACTGAATATGTCAGGTCAAATTTGGAGTGTCAAGGGAAAGAGAGTGAATTCCTTCAACATACTACATGTAAAGTACCTAAGGTTCTTGGTGACATTATGGAAAGCATCGCTGGTGCAGTATTTATAGACACCGATTTTAATGTTGACATGGTTTGGGAGATTTTCGAGCCATTGCTTTCTCCACTGATTACACCTGATAAGCTTGCATTGCCACCTTACCGTGAGTTGCTGGAGCTATGCAGTCACATTGGTTGCTTCTTAAATTCAAAATGCACCAGTAAAGGAGAAGAAGTAATTATAGAGATGTCACTGCAACTACGAGATGAGCTGCTGGTAGCACAAGGGCATGACAGAAACAAAAAGAGGGCAAAGGCAAAAGCAGCATCTCGTATTTTGGCAGATCTTAAGCAACAGGGTCTTTCAATTAAACAATGTTTGTCCAAGGCTAAACAGCTGGATATCGTGACTTCAGATCTTCAGTTTGACTTGACAAGTTCAGGAACACAACTCAGTTATTCTGATTTGAATGACTATCATATCCTAGAAGGTCTTTCCTCAGTAAAGAAAGAAGTTGTGCTTCCACTCAAAATGGAGAAAGGTGGACCTCGAAGTGCGCTTTTCAAGCTATGCAAGATTTTGCAGTGGCCAATGCCAGAATTCGAATTTGTGGAACAAAGGTTCAGGACTCCTATTGTTATGGATGGGGCGACAACAACAAACTTCAATAGCTTTGTTTCGACAATCACCTTGCACATACCTGACGCAACAACCATTACATTTCAAGGTGAGCGACGTACTGACAAAAAGAGTGCTCAGGATTCAGCATCCTTGATGATGCTTCACAAGCTTCAAGAACTCAAGATCTGTATATGCAAGACTTAGCAAAGCATCATTGAGACATGGGCCAATATGCCAGTTAACGATTGCGACTAGCTAATGCGAGCTACTTCCCTCCCAAAGTGAGATGCGACGAAAATATTTCTGAAAAGCTCGATGCTCCAGACTGTCACTGATCCTATGTTATTTTGGGGAAGAAGATCCCTATGGTATACTACCTTGCATTACCTGGATACATTGTTGTCGAGTTTCC
CDS Sequence
- >LOC_Os10g34430.1
ATGGTCGCCGTCATGCTCGCGCGCGAGCACGCACGCCGGGTGCGCGCCGGGGAGGCGCCGCGGCGGATCGTGGTGTTCCTCGCGCCCACCGTGCACCTCGTCCATCAGCAATTCGAGGTGATTCGTGAGTACACTGACCTCGACGTGATGATGTGCTCTGGAGCATCGCGGGTTGGCGAATGGGGCGCCGATCATTGGAAGGAGGAAGTTGGGAGAAATGAGATCGTTGTTATGACGCCACAGATACTGTTGGATGCTCTGCGGCATGCTTTTCTGACAATGAGTGCAGTGAGCTTGCTAATATTTGATGAATGTCATCGTGCTTGTGGAAGCCATCCATATGCACGAATAATGAAGGAATTTTATTTTGGGTCTCAGTGGAGGCCAGATGTATTTGGAATGACAGCCTCCCCCGTTGCTACTAAAGGTGCTTCCACACTACACAATTGTGAAGCACACATTTCTCAACTAGAACTAACCTTGGATGCCAAGATATACATCGTAGAAGATCGAAATGAGCTTGAGAGCTTTTCCCCTCCTACAACAATTGTGAACAAATACTATGATGCTTACATGGTTGATTTTGATAATCTGAAATCAAAGCTTCAGATATTTTCTGATGAGTTTGATTCTTTGTTGGTTGGTCTTCAAGAATCGCCATCTAATAAATTTAAAGACACCGATAATATCCTAGAGACTTCAAGAAAGAGCTTGTCCAGATACCATGGGAAAATATTGTACAGCCTAAACGATCTTGGTCCAATTATCACCTCTGAGGTAGTCAAAATACATATTGAAAGCGTTAAGCCATTATGTGATTCTGAAGACTGCATTTTTTCTAAAGCTAGCTTGTGCTTACATATGTCTTATTTTAAAGAAGCTTTAAGTCTAATAGAGGAAATTCTTCCACAAGGATATGGTGAACTAATGAAATCAGAATCTGGTTCTGAGGAATTAACTAAAAGGGGATACATTTCTTCAAAAGTGAATACGCTAATCAACATCTTCAAATCGTTTGGGTCATCAAATGAAGTGCTTTGCCTAATTTTCGTAGACAGAATTATAACAGCTAAAGCCGTCGAAAGGTTTATGAGAGGAATTGTTAACTTCTCTTGTTTTTCAATTTCTTACTTGACTGGAGGGAGTACATCAAAAGATGCTCTGAGTCCAGCAGTTCAGAGATTTACTTTGGATTTGTTCCGAGCTGGAAAGGTGAACTTGCTTTTTACAACAGATGTGACTGAAGAGGGCGTCGATGTACCTAACTGTTCTTGTGTGATACGCTTCGACCTACCCAGAACTGTTTGTAGCTATGTCCAATCTCGTGGTCGTGCTAGAAGGAACAACTCGGAATTTATTCTTATGATTGAGAGGGGAAACTTGCAGCAGCAAGAACACATATTTCGTATGATACAGACTGGTTACTATGTTAAAAACTGTGCACTCTATAGACACCCCAATGCTTTATCCTATGACTTGTCTATCCAAGGGATGTACACCTACCAAGTTCAGTCAACTGGAGCAACTATAACCGCAGATTGCTGTGTCAACCTAATTCGTAAATACTGTGAGAAGCTTCCTAAAGATAGGTATTTCATGCCAAAGCCTTCCTTTGAGGTGACCATTGAAGATGGATTATTCAAATGCACATTGACGCTACCTCGAAATGCAGCATTTCAAAGTATAGTTGGCCCTTTAAGCAGTTCAAGTAATTTATCCAAGCAGCTTGTATCCCTAGAGGCCTGCAAGAAATTGCATCAACTGGGAGAACTTAATGATCATCTTGTACCTTTGACTGAAGAACCTATGGATACAGATTTCACTACAGCAGATGAAAAATGCATATCTGGACCAGGAACAACTAAAAGGAAGGAGCTTCATGGTACTACATGTGTTCTTGCTTTATCAGGAACTTGGATTCATGACAGTGAAAATATTACACTGAATACTTACAGAATTGATTTTCTTTGTGACCAAGAGGGTGAAAACTATGCTGGGTTTGTTCTCTTAATGGAACCAGAACTTGATGATGATGTGGCACCCTCAAAAATGGATCTGTTCCTGATCCCTAATAAAATGGTCTACACCACTGTAACTCCTCGCGGAAAAGTTCAACTAAACAAAAAGCAGTTAGGTAAAGGGAAATTGTTCCAAGAATTCTTTTTCAATGGAATCTTTGGTAGATTATTTCATGGTTCTCGAAAAAGTGGAGCACAAAGGGATTTTATTTTCAAAAAGGGTCATGAAATACAGTGGAACACGGAAAGCATGTACTTGCTTTTACCTTTGAGGGATTCTTCATATATCCAGGATGACCTAAGCATACACTGGGAAGCAATTGAATCTTGTGCTGGTGCAGTTGAGCAGTTGTGGAGTTCGTATCAAGGAGATGAAAATGTCATTCCTGTAAATTGTATTCCACAAAAAAGAAGAGGGGGCCAAGAAGAAATTATTCATCTGGCCAATAAGTCTCTTCATTGTTCCAGCATCAAAGATTCAGTCGTGCTATCACTGCATACAGGAAGGATATACACTGTTCTTGATTTGATCTTAGACACAACTGCAGAGGACTCGTTTGATGAGATGTGTAAGGGGAAAGCCTCACCTTTTACTTCATTTGTGGACTATTACCATCAAAAGTATGGTATTATTATTCAACATCCAGAACAACCACTATTGCTGTTAAAGCAAAGCCACAATGCACACAATCTTCTCTTTTCAAAATTGAAGTATCTAGATGGCTCCACTGGCAAACCTCTGCTCATGGAAAAAGAACAAATTCATGCTCGGGTTCCACCTGAACTACTTATCCATCTCGATGTAACAACTGATATTCTGAAGTCATTTTATTTACTCCCTTCTGTAATACATCGGCTTCAGTCACTTATGCTAGCCAGCCAGCTTCGCAGAGAAATTGGTTACAATCAACACATACCAGTCACTTTGATTTTGGAAGCTATAACAACTTTAAGATGCTGTGAGACATTTTCTCTGGAGCGTTTAGAGCTGTTAGGAGACTCCGTGCTAAAGTATGTGGTAGGATGTGACCTTTTCCTAAGGTATCCTATGAAACATGAAGGTCAGCTCTCTGATATGAGATCCAAGGCTGTCTGCAATGCTACACTTCATAAACATGGAATATGGCGGTCGTTGCAGGGTTATGTACGTGATAATGCTTTTGACCCACGGCGTTGGGTTGCTCCTGGACAGATATCGTTGCGCCCTTTTCCTTGTAACTGTGGAATCGAGACTGCATTTGTTCCTTCTCATAGAAGGTATATCCGAGATGACCCATCTTTTTTTGTGGGAAAACCATGTGACAGAGGTCATAGGTGGATGTGCTCAAAAACAATATCTGATTGTGTTGAAGCACTGGTTGGAGCATATTATGTTGGTGGTGGCATTGCTGCTGCACTTTGGGTTATGAGGTGGTTTGGAATCGATATCAAATGTGATATGAAGCTATTGCAGGAAGTGAAGTTCAATGCATCTCATTTATGCTCCTTATCAAAAATAAATGACATTGAGGAACTGGAAGCAAAACTGAAGTACAACTTCTCAGTCAAGGGCCTTCTTTTGGAAGCCATAACTCATCCATCTCTGCAGGAATTAGGTGTTGATTACTGTTACCAGCGTCTTGAATTTCTTGGTGATTCTGTGCTGGATCTACTTCTTACACGTCATCTCTATGCTACTCATACTGATGTTGATCCTGGAGAATTAACGGATTTACGCTCCGCTTTGGTTAGTAATGAGAATTTTGCACAAGCAGTTGTAAGAAACAACATTCACAGTCATCTACAACATGGATCCGGAATACTTTTGGAGCAAATTACTGAATATGTCAGGTCAAATTTGGAGTGTCAAGGGAAAGAGAGTGAATTCCTTCAACATACTACATGTAAAGTACCTAAGGTTCTTGGTGACATTATGGAAAGCATCGCTGGTGCAGTATTTATAGACACCGATTTTAATGTTGACATGGTTTGGGAGATTTTCGAGCCATTGCTTTCTCCACTGATTACACCTGATAAGCTTGCATTGCCACCTTACCGTGAGTTGCTGGAGCTATGCAGTCACATTGGTTGCTTCTTAAATTCAAAATGCACCAGTAAAGGAGAAGAAGTAATTATAGAGATGTCACTGCAACTACGAGATGAGCTGCTGGTAGCACAAGGGCATGACAGAAACAAAAAGAGGGCAAAGGCAAAAGCAGCATCTCGTATTTTGGCAGATCTTAAGCAACAGGGTCTTTCAATTAAACAATGTTTGTCCAAGGCTAAACAGCTGGATATCGTGACTTCAGATCTTCAGTTTGACTTGACAAGTTCAGGAACACAACTCAGTTATTCTGATTTGAATGACTATCATATCCTAGAAGGTCTTTCCTCAGTAAAGAAAGAAGTTGTGCTTCCACTCAAAATGGAGAAAGGTGGACCTCGAAGTGCGCTTTTCAAGCTATGCAAGATTTTGCAGTGGCCAATGCCAGAATTCGAATTTGTGGAACAAAGGTTCAGGACTCCTATTGTTATGGATGGGGCGACAACAACAAACTTCAATAGCTTTGTTTCGACAATCACCTTGCACATACCTGACGCAACAACCATTACATTTCAAGGTGAGCGACGTACTGACAAAAAGAGTGCTCAGGATTCAGCATCCTTGATGATGCTTCACAAGCTTCAAGAACTCAAGATCTGTATATGCAAGACTTAG
Protein Sequence
- >LOC_Os10g34430.1
MVAVMLAREHARRVRAGEAPRRIVVFLAPTVHLVHQQFEVIREYTDLDVMMCSGASRVGEWGADHWKEEVGRNEIVVMTPQILLDALRHAFLTMSAVSLLIFDECHRACGSHPYARIMKEFYFGSQWRPDVFGMTASPVATKGASTLHNCEAHISQLELTLDAKIYIVEDRNELESFSPPTTIVNKYYDAYMVDFDNLKSKLQIFSDEFDSLLVGLQESPSNKFKDTDNILETSRKSLSRYHGKILYSLNDLGPIITSEVVKIHIESVKPLCDSEDCIFSKASLCLHMSYFKEALSLIEEILPQGYGELMKSESGSEELTKRGYISSKVNTLINIFKSFGSSNEVLCLIFVDRIITAKAVERFMRGIVNFSCFSISYLTGGSTSKDALSPAVQRFTLDLFRAGKVNLLFTTDVTEEGVDVPNCSCVIRFDLPRTVCSYVQSRGRARRNNSEFILMIERGNLQQQEHIFRMIQTGYYVKNCALYRHPNALSYDLSIQGMYTYQVQSTGATITADCCVNLIRKYCEKLPKDRYFMPKPSFEVTIEDGLFKCTLTLPRNAAFQSIVGPLSSSSNLSKQLVSLEACKKLHQLGELNDHLVPLTEEPMDTDFTTADEKCISGPGTTKRKELHGTTCVLALSGTWIHDSENITLNTYRIDFLCDQEGENYAGFVLLMEPELDDDVAPSKMDLFLIPNKMVYTTVTPRGKVQLNKKQLGKGKLFQEFFFNGIFGRLFHGSRKSGAQRDFIFKKGHEIQWNTESMYLLLPLRDSSYIQDDLSIHWEAIESCAGAVEQLWSSYQGDENVIPVNCIPQKRRGGQEEIIHLANKSLHCSSIKDSVVLSLHTGRIYTVLDLILDTTAEDSFDEMCKGKASPFTSFVDYYHQKYGIIIQHPEQPLLLLKQSHNAHNLLFSKLKYLDGSTGKPLLMEKEQIHARVPPELLIHLDVTTDILKSFYLLPSVIHRLQSLMLASQLRREIGYNQHIPVTLILEAITTLRCCETFSLERLELLGDSVLKYVVGCDLFLRYPMKHEGQLSDMRSKAVCNATLHKHGIWRSLQGYVRDNAFDPRRWVAPGQISLRPFPCNCGIETAFVPSHRRYIRDDPSFFVGKPCDRGHRWMCSKTISDCVEALVGAYYVGGGIAAALWVMRWFGIDIKCDMKLLQEVKFNASHLCSLSKINDIEELEAKLKYNFSVKGLLLEAITHPSLQELGVDYCYQRLEFLGDSVLDLLLTRHLYATHTDVDPGELTDLRSALVSNENFAQAVVRNNIHSHLQHGSGILLEQITEYVRSNLECQGKESEFLQHTTCKVPKVLGDIMESIAGAVFIDTDFNVDMVWEIFEPLLSPLITPDKLALPPYRELLELCSHIGCFLNSKCTSKGEEVIIEMSLQLRDELLVAQGHDRNKKRAKAKAASRILADLKQQGLSIKQCLSKAKQLDIVTSDLQFDLTSSGTQLSYSDLNDYHILEGLSSVKKEVVLPLKMEKGGPRSALFKLCKILQWPMPEFEFVEQRFRTPIVMDGATTTNFNSFVSTITLHIPDATTITFQGERRTDKKSAQDSASLMMLHKLQELKICICKT*