Gene Details:

• MSU gene ID: LOC_Os10g26560
• RAPdb gene ID: Os10g0405500
• Gene Symbol: PAIR3
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Several key meiotic proteins, including ZEP1 and OsMER3, were not loaded normally onto chromosomes in Oscom1 mutants, whereas the localization of OsREC8, PAIR2 and PAIR3 seemed to be normal.
• In this study, we identified a novel gene, PAIR3 (HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS 3), required for homologous chromosome pairing and synapsis in rice.
• PAIR3 is preferentially expressed in reproductive organs, especially in pollen mother cells and the ovule tissues during meiosis.
• Our results suggest that PAIR3 plays a crucial role in homologous chromosome pairing and synapsis in meiosis.
• Mutation of the rice gene PAIR3 results in lack of bivalent formation in meiosis.
• Two independent alleles, designated PAIR3-1 and PAIR3-2, were identified in our T-DNA insertional mutant library which could not form bivalents due to failure of homologous chromosome pairing and synapsis at diakinesis, resulting in sterility in both male and female gametes.

Function-related keywords:

• meiotic ,  meiosis ,  sterility ,  pollen ,  reproductive

Literature:

• Mutation of the rice gene PAIR3 results in lack of bivalent formation in meiosis .  DOI:  10.1111/j.1365-313X.2009.03870.x ;  PMID:  19392701
• The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis .  DOI:  10.1111/j.1365-313X.2012.05025.x ;  PMID:  22507309
• Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells .  DOI:  10.3389/fpls.2020.600820 ;  PMID:  33304374

Related News:

Gene Resources:

• NCBI ID: FJ449712
• UniProt accessions:

Sequences: