Information report for OsDRP1E
Gene Details
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Functional Descriptions
- Furthermore, confocal microscopy showed that the E409V mutation impairs localization of OsDRP1E to the mitochondria.
- We used a map-based cloning strategy to isolate OsDRP1E from the lesion mimic mutant dj-lm and confirmed that the E409V mutation in OsDRP1E causes spontaneous cell death in rice.
- The Rice Dynamin-Related Protein OsDRP1E Negatively Regulates Programmed Cell Death by Controlling the Release of Cytochrome c from Mitochondria.
- Taken together, our results demonstrate that the mitochondria-localized protein OsDRP1E functions as a negative regulator of cytochrome c release and PCD in plants.
Functional Keywords
- mitochondria , map-based-cloning , cell-death , PCD , lesion , lesion-mimic
Literature and News
Gene Resources
- UniProt: Q650Z3
- EMBL: AP014965
- AlphaFoldDB: Q650Z3
- EnsemblPlants: Os09t0572900-01
- Gramene: Os09t0572900-01
- KEGG: osa:4347929
- Orthologous matrix: DGHYRNI
- InterPro: IPR000375, IPR001401, IPR003130
- PANTHER: PTHR11566, PTHR11566:SF151
- SUPFAM: SSF52540
- PROSITE: PS00410, PS51388, PS51718
- Gene3D: 1.20.120.1240, 3.40.50.300
- OrthoDB: Q650Z3
- SWISS-MODEL: Q650Z3
- Conserved Domain Database: cd08771
- eggNOG: KOG0446
Homologs
- Malus domestica: MDP0000167868
Sequences
cDNA Sequence
- >LOC_Os09g39960.1
GCGCGTGGTTTCTTTCTTCTTCCTTAAACCTGAATCAATCTTTCTTTCTTTCTTTCTTTCTTGTCTACTAGTCTTCTACTGGAGTAGGTTCTACGAGACACAAATTAGACAGGAGAGATCGAGTTTGAAGGCAGGAAGGCAGGCGATGGCGAGCATGGAGGGTCTGATCGGCCTGATGAACCGCATCCAGCGAGCCTGCACCGCCCTCGGAGACCACGGAGGTGGAGAAGGAGCCAACCTCCCTACCCTCTGGGAGTCTCTCCCCACCATCGCCGTCGTCGGAGGCCAGAGTTCGGGCAAGTCCTCCGTGCTAGAGAGCATTGTTGGCAGAGATTTCCTTCCCCGTGGTTCTGGAATCGTGACACGGAGGCCATTAGTTCTTCAGCTGCATCAGATCGACAAAGGGGCCCACGATTATGCAGAGTTCTTACACTTGCCCAAAACAAGGTTTTCAGATTTTGCTCTTGTTCGTCAAGAAATTGCAGATGAGACAGATAGAGTGACTGGGAAAACTAAACAAATATCCCCTGTGCCAATACATCTCAGCATCTACTCACCCAACGTCGTGAACTTAACATTGATTGATCTTCCTGGATTGACAAAAGTCGCTGTAGAGGGACAACCTGAAAGTGTTGTTCATGATATAGAGAATATGGTTCGGTCGTATGTTGAGAAGCCCAATTGTATCATTTTGGCTATATCTCCAGCAAACCAGGACATTGCCACTTCTGATGCCATTAAGCTTTCGAAGGAGGTTGACCCATCAGGTGAGAGGACATTCGGTGTGTTGACAAAGTTGGACTTGATGGACAAGGGAACAAACGCTCTTGATGTTCTTGAGGGAAGAGCCTATCGTCTTCAGTATCCGTGGGTTGGAATTGTCAACCGCTCACAAGCAGATATTAACAGGAAAGTTGATATGATTGTTGCAAGAGAAAAGGAAAGAGAGTATTTTGAAAATAGTCCTGATTATGCACACCTAGCCAGTAAGATGGGTTCTGTGTATCTAGCTAAGCTTCTTTCTCAGCATCTTGAAGCCGTTATTAAAGCACGCATTCCTAGCATCACATCATTAATCAACAAAACTATAGATGAACTTGAATCGGAGCTGGATACCATTGGGAAAGAAGTGGCTGCTGATCCAGGGGCTCAACTGTACACTATATTGGAGCTCTGTCGTGCTTTTGACCGTGTTTTCAAGGAACATCTGGACGGAGGGAGATCAGGTGGTGATAAAATTTATGGCGTGTTTGATCATAAGCTCCCTGCCGCTTTTAGGAAGCTGCCTTTTGATCGTTATCTATCCGTGCAAAATGTGAAGAAGGTGGTATCAGAAGCAGATGGCTATCAGCCTCATCTTATTGCTCCTGAACAAGGTTACCGTCGTCTTGTTGAAGCCGGCCTTGCGTATTTCAAGGGACCAGCTGAAGCTACAGTCGATGCGGTCCATGTTGTTTTAAGGGACTTGGTGAGGAAATCCATAGGAGAGACAGAGCCACTGAGAAGATTCCCTACCCTGCAAGCTGCGATTGCAACTGCTGCTAATGAAGCTCTGGAAAGGTTTCGGGAGGATGGACGTAGCACTGCACTTCGGCTTGTTGACATGGAGGCATATTTGACAGTGGAATTCTTCCGGAAACTCCCGCAAGATCCAGATAGTGGCAGCAAGGTTGGGAATAATACCAATGAATCCAATGGCTCAGGCTCAGGCTCAGTGACAGTGGACCGCTACGGCGACGGGCACTACAGGAATATCGCGTCCAATGTGTCCCAGTACATAAAGATGGTGGGAGACCAACTGTTACACAAGATCCCAAAGGCGGTGGTGCACTGTCAGGTCCGAGAAGCCAAGAGGTCTCTGCTTAACCATTTCTACGTGCACATCGGGAAGAAAGAGGCGAGCCAGTTTGGGCATTTACTGGATGAGGACCCAGCGATGCTTGAGCGTAGGCAGCAATGCTGGAAGAGGTTGGAGCTGTACAAATCGGCTAGGGATGAAATCGACTCTGTCGCATGGACCAGGTAGACACAAACATATACATGGTGGCTAGTATCTTTTGTCGCAGCTGCGTGTAGTTTGGTTTGGGCAGATCTAACTTCCATTTGTCAGGCAGGCACTATTTTCCCTTGGTATATAGTATATACTATACTATCTTACGAATTGATGGACGTTATATATCTGTATATTTTGTCAGTAGATCATCCTTCGTACATGTGCACCCCGACCCGTGCCATGCTGGTTTCAACAGTTTTTCTTTTGTTATTCTTTCTAGTGGTTGGCTTCTCTCTGTTGTCACGGTATTACATATGTTGTATTATTCCCTCCGTTTCACAATGTAAGTCATTCTAGCA
CDS Sequence
- >LOC_Os09g39960.1
ATGGCGAGCATGGAGGGTCTGATCGGCCTGATGAACCGCATCCAGCGAGCCTGCACCGCCCTCGGAGACCACGGAGGTGGAGAAGGAGCCAACCTCCCTACCCTCTGGGAGTCTCTCCCCACCATCGCCGTCGTCGGAGGCCAGAGTTCGGGCAAGTCCTCCGTGCTAGAGAGCATTGTTGGCAGAGATTTCCTTCCCCGTGGTTCTGGAATCGTGACACGGAGGCCATTAGTTCTTCAGCTGCATCAGATCGACAAAGGGGCCCACGATTATGCAGAGTTCTTACACTTGCCCAAAACAAGGTTTTCAGATTTTGCTCTTGTTCGTCAAGAAATTGCAGATGAGACAGATAGAGTGACTGGGAAAACTAAACAAATATCCCCTGTGCCAATACATCTCAGCATCTACTCACCCAACGTCGTGAACTTAACATTGATTGATCTTCCTGGATTGACAAAAGTCGCTGTAGAGGGACAACCTGAAAGTGTTGTTCATGATATAGAGAATATGGTTCGGTCGTATGTTGAGAAGCCCAATTGTATCATTTTGGCTATATCTCCAGCAAACCAGGACATTGCCACTTCTGATGCCATTAAGCTTTCGAAGGAGGTTGACCCATCAGGTGAGAGGACATTCGGTGTGTTGACAAAGTTGGACTTGATGGACAAGGGAACAAACGCTCTTGATGTTCTTGAGGGAAGAGCCTATCGTCTTCAGTATCCGTGGGTTGGAATTGTCAACCGCTCACAAGCAGATATTAACAGGAAAGTTGATATGATTGTTGCAAGAGAAAAGGAAAGAGAGTATTTTGAAAATAGTCCTGATTATGCACACCTAGCCAGTAAGATGGGTTCTGTGTATCTAGCTAAGCTTCTTTCTCAGCATCTTGAAGCCGTTATTAAAGCACGCATTCCTAGCATCACATCATTAATCAACAAAACTATAGATGAACTTGAATCGGAGCTGGATACCATTGGGAAAGAAGTGGCTGCTGATCCAGGGGCTCAACTGTACACTATATTGGAGCTCTGTCGTGCTTTTGACCGTGTTTTCAAGGAACATCTGGACGGAGGGAGATCAGGTGGTGATAAAATTTATGGCGTGTTTGATCATAAGCTCCCTGCCGCTTTTAGGAAGCTGCCTTTTGATCGTTATCTATCCGTGCAAAATGTGAAGAAGGTGGTATCAGAAGCAGATGGCTATCAGCCTCATCTTATTGCTCCTGAACAAGGTTACCGTCGTCTTGTTGAAGCCGGCCTTGCGTATTTCAAGGGACCAGCTGAAGCTACAGTCGATGCGGTCCATGTTGTTTTAAGGGACTTGGTGAGGAAATCCATAGGAGAGACAGAGCCACTGAGAAGATTCCCTACCCTGCAAGCTGCGATTGCAACTGCTGCTAATGAAGCTCTGGAAAGGTTTCGGGAGGATGGACGTAGCACTGCACTTCGGCTTGTTGACATGGAGGCATATTTGACAGTGGAATTCTTCCGGAAACTCCCGCAAGATCCAGATAGTGGCAGCAAGGTTGGGAATAATACCAATGAATCCAATGGCTCAGGCTCAGGCTCAGTGACAGTGGACCGCTACGGCGACGGGCACTACAGGAATATCGCGTCCAATGTGTCCCAGTACATAAAGATGGTGGGAGACCAACTGTTACACAAGATCCCAAAGGCGGTGGTGCACTGTCAGGTCCGAGAAGCCAAGAGGTCTCTGCTTAACCATTTCTACGTGCACATCGGGAAGAAAGAGGCGAGCCAGTTTGGGCATTTACTGGATGAGGACCCAGCGATGCTTGAGCGTAGGCAGCAATGCTGGAAGAGGTTGGAGCTGTACAAATCGGCTAGGGATGAAATCGACTCTGTCGCATGGACCAGGTAG
Protein Sequence
- >LOC_Os09g39960.1
MASMEGLIGLMNRIQRACTALGDHGGGEGANLPTLWESLPTIAVVGGQSSGKSSVLESIVGRDFLPRGSGIVTRRPLVLQLHQIDKGAHDYAEFLHLPKTRFSDFALVRQEIADETDRVTGKTKQISPVPIHLSIYSPNVVNLTLIDLPGLTKVAVEGQPESVVHDIENMVRSYVEKPNCIILAISPANQDIATSDAIKLSKEVDPSGERTFGVLTKLDLMDKGTNALDVLEGRAYRLQYPWVGIVNRSQADINRKVDMIVAREKEREYFENSPDYAHLASKMGSVYLAKLLSQHLEAVIKARIPSITSLINKTIDELESELDTIGKEVAADPGAQLYTILELCRAFDRVFKEHLDGGRSGGDKIYGVFDHKLPAAFRKLPFDRYLSVQNVKKVVSEADGYQPHLIAPEQGYRRLVEAGLAYFKGPAEATVDAVHVVLRDLVRKSIGETEPLRRFPTLQAAIATAANEALERFREDGRSTALRLVDMEAYLTVEFFRKLPQDPDSGSKVGNNTNESNGSGSGSVTVDRYGDGHYRNIASNVSQYIKMVGDQLLHKIPKAVVHCQVREAKRSLLNHFYVHIGKKEASQFGHLLDEDPAMLERRQQCWKRLELYKSARDEIDSVAWTR*