Gene Details:
- MSU gene ID: LOC_Os09g39960
- RAPdb gene ID: Os09g0572900
- Gene Symbol: OsDRP1E
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Furthermore, confocal microscopy showed that the E409V mutation impairs localization of OsDRP1E to the mitochondria.
- We used a map-based cloning strategy to isolate OsDRP1E from the lesion mimic mutant dj-lm and confirmed that the E409V mutation in OsDRP1E causes spontaneous cell death in rice.
- The Rice Dynamin-Related Protein OsDRP1E Negatively Regulates Programmed Cell Death by Controlling the Release of Cytochrome c from Mitochondria.
- Taken together, our results demonstrate that the mitochondria-localized protein OsDRP1E functions as a negative regulator of cytochrome c release and PCD in plants.
Function-related keywords:
- mitochondria , map-based-cloning , cell-death , PCD , lesion , lesion-mimic
Literature:
- The Rice Dynamin-Related Protein OsDRP1E Negatively Regulates Programmed Cell Death by Controlling the Release of Cytochrome c from Mitochondria . DOI: 10.1371/journal.ppat.1006157 ; PMID: 28081268
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os09g39960.1
GCGCGTGGTTTCTTTCTTCTTCCTTAAACCTGAATCAATCTTTCTTTCTTTCTTTCTTTCTTGTCTACTAGTCTTCTACTGGAGTAGGTTCTACGAGACACAAATTAGACAGGAGAGATCGAGTTTGAAGGCAGGAAGGCAGGCGATGGCGAGCATGGAGGGTCTGATCGGCCTGATGAACCGCATCCAGCGAGCCTGCACCGCCCTCGGAGACCACGGAGGTGGAGAAGGAGCCAACCTCCCTACCCTCTGGGAGTCTCTCCCCACCATCGCCGTCGTCGGAGGCCAGAGTTCGGGCAAGTCCTCCGTGCTAGAGAGCATTGTTGGCAGAGATTTCCTTCCCCGTGGTTCTGGAATCGTGACACGGAGGCCATTAGTTCTTCAGCTGCATCAGATCGACAAAGGGGCCCACGATTATGCAGAGTTCTTACACTTGCCCAAAACAAGGTTTTCAGATTTTGCTCTTGTTCGTCAAGAAATTGCAGATGAGACAGATAGAGTGACTGGGAAAACTAAACAAATATCCCCTGTGCCAATACATCTCAGCATCTACTCACCCAACGTCGTGAACTTAACATTGATTGATCTTCCTGGATTGACAAAAGTCGCTGTAGAGGGACAACCTGAAAGTGTTGTTCATGATATAGAGAATATGGTTCGGTCGTATGTTGAGAAGCCCAATTGTATCATTTTGGCTATATCTCCAGCAAACCAGGACATTGCCACTTCTGATGCCATTAAGCTTTCGAAGGAGGTTGACCCATCAGGTGAGAGGACATTCGGTGTGTTGACAAAGTTGGACTTGATGGACAAGGGAACAAACGCTCTTGATGTTCTTGAGGGAAGAGCCTATCGTCTTCAGTATCCGTGGGTTGGAATTGTCAACCGCTCACAAGCAGATATTAACAGGAAAGTTGATATGATTGTTGCAAGAGAAAAGGAAAGAGAGTATTTTGAAAATAGTCCTGATTATGCACACCTAGCCAGTAAGATGGGTTCTGTGTATCTAGCTAAGCTTCTTTCTCAGCATCTTGAAGCCGTTATTAAAGCACGCATTCCTAGCATCACATCATTAATCAACAAAACTATAGATGAACTTGAATCGGAGCTGGATACCATTGGGAAAGAAGTGGCTGCTGATCCAGGGGCTCAACTGTACACTATATTGGAGCTCTGTCGTGCTTTTGACCGTGTTTTCAAGGAACATCTGGACGGAGGGAGATCAGGTGGTGATAAAATTTATGGCGTGTTTGATCATAAGCTCCCTGCCGCTTTTAGGAAGCTGCCTTTTGATCGTTATCTATCCGTGCAAAATGTGAAGAAGGTGGTATCAGAAGCAGATGGCTATCAGCCTCATCTTATTGCTCCTGAACAAGGTTACCGTCGTCTTGTTGAAGCCGGCCTTGCGTATTTCAAGGGACCAGCTGAAGCTACAGTCGATGCGGTCCATGTTGTTTTAAGGGACTTGGTGAGGAAATCCATAGGAGAGACAGAGCCACTGAGAAGATTCCCTACCCTGCAAGCTGCGATTGCAACTGCTGCTAATGAAGCTCTGGAAAGGTTTCGGGAGGATGGACGTAGCACTGCACTTCGGCTTGTTGACATGGAGGCATATTTGACAGTGGAATTCTTCCGGAAACTCCCGCAAGATCCAGATAGTGGCAGCAAGGTTGGGAATAATACCAATGAATCCAATGGCTCAGGCTCAGGCTCAGTGACAGTGGACCGCTACGGCGACGGGCACTACAGGAATATCGCGTCCAATGTGTCCCAGTACATAAAGATGGTGGGAGACCAACTGTTACACAAGATCCCAAAGGCGGTGGTGCACTGTCAGGTCCGAGAAGCCAAGAGGTCTCTGCTTAACCATTTCTACGTGCACATCGGGAAGAAAGAGGCGAGCCAGTTTGGGCATTTACTGGATGAGGACCCAGCGATGCTTGAGCGTAGGCAGCAATGCTGGAAGAGGTTGGAGCTGTACAAATCGGCTAGGGATGAAATCGACTCTGTCGCATGGACCAGGTAGACACAAACATATACATGGTGGCTAGTATCTTTTGTCGCAGCTGCGTGTAGTTTGGTTTGGGCAGATCTAACTTCCATTTGTCAGGCAGGCACTATTTTCCCTTGGTATATAGTATATACTATACTATCTTACGAATTGATGGACGTTATATATCTGTATATTTTGTCAGTAGATCATCCTTCGTACATGTGCACCCCGACCCGTGCCATGCTGGTTTCAACAGTTTTTCTTTTGTTATTCTTTCTAGTGGTTGGCTTCTCTCTGTTGTCACGGTATTACATATGTTGTATTATTCCCTCCGTTTCACAATGTAAGTCATTCTAGCA
CDS Sequence
- >LOC_Os09g39960.1
ATGGCGAGCATGGAGGGTCTGATCGGCCTGATGAACCGCATCCAGCGAGCCTGCACCGCCCTCGGAGACCACGGAGGTGGAGAAGGAGCCAACCTCCCTACCCTCTGGGAGTCTCTCCCCACCATCGCCGTCGTCGGAGGCCAGAGTTCGGGCAAGTCCTCCGTGCTAGAGAGCATTGTTGGCAGAGATTTCCTTCCCCGTGGTTCTGGAATCGTGACACGGAGGCCATTAGTTCTTCAGCTGCATCAGATCGACAAAGGGGCCCACGATTATGCAGAGTTCTTACACTTGCCCAAAACAAGGTTTTCAGATTTTGCTCTTGTTCGTCAAGAAATTGCAGATGAGACAGATAGAGTGACTGGGAAAACTAAACAAATATCCCCTGTGCCAATACATCTCAGCATCTACTCACCCAACGTCGTGAACTTAACATTGATTGATCTTCCTGGATTGACAAAAGTCGCTGTAGAGGGACAACCTGAAAGTGTTGTTCATGATATAGAGAATATGGTTCGGTCGTATGTTGAGAAGCCCAATTGTATCATTTTGGCTATATCTCCAGCAAACCAGGACATTGCCACTTCTGATGCCATTAAGCTTTCGAAGGAGGTTGACCCATCAGGTGAGAGGACATTCGGTGTGTTGACAAAGTTGGACTTGATGGACAAGGGAACAAACGCTCTTGATGTTCTTGAGGGAAGAGCCTATCGTCTTCAGTATCCGTGGGTTGGAATTGTCAACCGCTCACAAGCAGATATTAACAGGAAAGTTGATATGATTGTTGCAAGAGAAAAGGAAAGAGAGTATTTTGAAAATAGTCCTGATTATGCACACCTAGCCAGTAAGATGGGTTCTGTGTATCTAGCTAAGCTTCTTTCTCAGCATCTTGAAGCCGTTATTAAAGCACGCATTCCTAGCATCACATCATTAATCAACAAAACTATAGATGAACTTGAATCGGAGCTGGATACCATTGGGAAAGAAGTGGCTGCTGATCCAGGGGCTCAACTGTACACTATATTGGAGCTCTGTCGTGCTTTTGACCGTGTTTTCAAGGAACATCTGGACGGAGGGAGATCAGGTGGTGATAAAATTTATGGCGTGTTTGATCATAAGCTCCCTGCCGCTTTTAGGAAGCTGCCTTTTGATCGTTATCTATCCGTGCAAAATGTGAAGAAGGTGGTATCAGAAGCAGATGGCTATCAGCCTCATCTTATTGCTCCTGAACAAGGTTACCGTCGTCTTGTTGAAGCCGGCCTTGCGTATTTCAAGGGACCAGCTGAAGCTACAGTCGATGCGGTCCATGTTGTTTTAAGGGACTTGGTGAGGAAATCCATAGGAGAGACAGAGCCACTGAGAAGATTCCCTACCCTGCAAGCTGCGATTGCAACTGCTGCTAATGAAGCTCTGGAAAGGTTTCGGGAGGATGGACGTAGCACTGCACTTCGGCTTGTTGACATGGAGGCATATTTGACAGTGGAATTCTTCCGGAAACTCCCGCAAGATCCAGATAGTGGCAGCAAGGTTGGGAATAATACCAATGAATCCAATGGCTCAGGCTCAGGCTCAGTGACAGTGGACCGCTACGGCGACGGGCACTACAGGAATATCGCGTCCAATGTGTCCCAGTACATAAAGATGGTGGGAGACCAACTGTTACACAAGATCCCAAAGGCGGTGGTGCACTGTCAGGTCCGAGAAGCCAAGAGGTCTCTGCTTAACCATTTCTACGTGCACATCGGGAAGAAAGAGGCGAGCCAGTTTGGGCATTTACTGGATGAGGACCCAGCGATGCTTGAGCGTAGGCAGCAATGCTGGAAGAGGTTGGAGCTGTACAAATCGGCTAGGGATGAAATCGACTCTGTCGCATGGACCAGGTAG
Protein Sequence
- >LOC_Os09g39960.1
MASMEGLIGLMNRIQRACTALGDHGGGEGANLPTLWESLPTIAVVGGQSSGKSSVLESIVGRDFLPRGSGIVTRRPLVLQLHQIDKGAHDYAEFLHLPKTRFSDFALVRQEIADETDRVTGKTKQISPVPIHLSIYSPNVVNLTLIDLPGLTKVAVEGQPESVVHDIENMVRSYVEKPNCIILAISPANQDIATSDAIKLSKEVDPSGERTFGVLTKLDLMDKGTNALDVLEGRAYRLQYPWVGIVNRSQADINRKVDMIVAREKEREYFENSPDYAHLASKMGSVYLAKLLSQHLEAVIKARIPSITSLINKTIDELESELDTIGKEVAADPGAQLYTILELCRAFDRVFKEHLDGGRSGGDKIYGVFDHKLPAAFRKLPFDRYLSVQNVKKVVSEADGYQPHLIAPEQGYRRLVEAGLAYFKGPAEATVDAVHVVLRDLVRKSIGETEPLRRFPTLQAAIATAANEALERFREDGRSTALRLVDMEAYLTVEFFRKLPQDPDSGSKVGNNTNESNGSGSGSVTVDRYGDGHYRNIASNVSQYIKMVGDQLLHKIPKAVVHCQVREAKRSLLNHFYVHIGKKEASQFGHLLDEDPAMLERRQQCWKRLELYKSARDEIDSVAWTR*