Gene Details:
- MSU gene ID: LOC_Os09g34060
- RAPdb gene ID: Os09g0516200
- Gene Symbol: RF2a OsbZIP75
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Transgenic rice plants that overexpress transcription factors RF2a and RF2b are tolerant to rice tungro virus replication and disease.
- RF2a, which stimulates Box II-dependent transcription in a homologous in vitro transcription system, accumulates in nuclei of phloem and certain other cell types in shoots, but is found at only very low levels in roots.
- Conversely, lines with elevated expression of RF2a or RF2b showed weak or no symptoms of infection after Agrobacterium inoculation of RTBV, whereas control plants showed severe stunting and leaf discoloration.
- RF2b, a rice bZIP transcription activator, interacts with RF2a and is involved in symptom development of rice tungro disease.
- When a fusion gene comprising the cauliflower mosaic virus 35S promoter and RF2a cDNA was coexpressed with the GUS reporter genes, GUS activity was increased by 2-20-fold.
- Transcription factor RF2a alters expression of the rice tungro bacilliform virus promoter in transgenic tobacco plants.
- Rice transcription factor RF2a binds to the BoxII cis element of the promoter of rice tungro bacilliform virus and activates promoter expression.
- Functional analysis of the activation domain of RF2a, a rice transcription factor.
- Transgenic antisense plants in which RF2a accumulation was suppressed had normal roots but stunted, twisted leaves with small, disorganized vascular bundles, an enlarged sclerenchyma and large air spaces.
- Two host transcription factors, RF2a and RF2b, regulate expression of the RTBV promoter and are important for plant development.
- We also demonstrate a physical interaction between OsTBP2 and RF2a, a rice bZIP transcription factor that bound to the box II cis element of the promoter of Rice tungro bacilliform virus, resulting in enhanced transcription from the viral promoter.
- We conclude that OsTBP2 undergoes promoter-specific functional interactions with both the basal transcription factor OsTFIIB and the accessory transcription factor RF2a.
- Rice TATA Binding Protein Interacts Functionally with Transcription Factor IIB and the RF2a bZIP Transcriptional Activator in an Enhanced Plant in Vitro Transcription System.
- RF2a is a bZIP transcription factor that regulates expression of the promoter of rice tungro bacilliform badnavirus.
- Functional analysis of RF2a, a rice transcription factor.
Function-related keywords:
- disease , shoot , leaf , flower , transcription-factor , vascular-bundle , root
Literature:
- RF2a, a bZIP transcriptional activator of the phloem-specific rice tungro bacilliform virus promoter, functions in vascular development . DOI: 10.1093/emboj/16.17.5247 ; PMID: 9311985
- Genome-wide analysis of basic leucine zipper transcription factor families in Arabidopsis thaliana, Oryza sativa and Populus trichocarpa . DOI: 10.1007/s11741-009-0216-3
- Functional analysis of RF2a, a rice transcription factor . DOI: 10.1074/jbc.M304862200 ; PMID: 12855676
- Functional analysis of the activation domain of RF2a, a rice transcription factor . DOI: 10.1111/j.1467-7652.2010.00520.x ; PMID: 20408988
- Genomic survey and gene expression analysis of the basic leucine zipper transcription factor family in rice . DOI: 10.1104/pp.107.112821 ; PMID: 18065552
- Rice TATA binding protein interacts functionally with transcription factor IIB and the RF2a bZIP transcriptional activator in an enhanced plant in vitro transcription system . DOI: 10.1105/tpc.010364 ; PMID: 11971135
- Transcription factor RF2a alters expression of the rice tungro bacilliform virus promoter in transgenic tobacco plants . DOI: 10.1073/pnas.121186398 ; PMID: 11390974
- RF2b, a rice bZIP transcription activator, interacts with RF2a and is involved in symptom development of rice tungro disease . DOI: 10.1073/pnas.0307687100 ; PMID: 14704272
- Transgenic rice plants that overexpress transcription factors RF2a and RF2b are tolerant to rice tungro virus replication and disease . DOI: 10.1073/pnas.0810303105 ; PMID: 19104064
Related News:
Gene Resources:
- NCBI ID: AF005492
- UniProt accessions:
Sequences:
cDNA Sequence
- >LOC_Os09g34060.1
GCTTGTTGCATTTTACTGTCCCCATGCAGACAATGCCAAAGGGATAAACAGAGCTAAAATTGGTGAAAATTCACTCGAATCCAAATGTAAACAACCCATTTTTCTCCTGTTCCAATCCCATCCATTCCATTCCATTCCTTCTCCCTGTGCTCGGATTCCTGTTCTTGCAGCTGATCCCTAGATCTTCCTCTTTGCCCGAGAATTTTCCGCCCAATTCCCCACTCCGATTCCTCTTCTTTCGCCCAAATTTTGGCTCAACATTTCGCAGCGCAATCTCGAGCTGAATCTTGGGGGGTAAAGCTTTGCTTCTTGGAATCTTGGTGCGGTTTTTGGGGGAGATTTGCGAGCGTTTGGAGCCGAGAAGATGAACAGGGAGAAATCCCCGATCCCGGGAGACGGCGGCGACGGGTTGCCGCCGCAGGCCACCCGCCGGGCGGGCCCTCCGGCGGCGGCGGCGGCGGCGGAGTACGACATCAGCCGCATGCCGGATTTCCCGACGAGGAACCCCGGCCACAGGCGCGCCCACTCCGAGATCCTGAGCCTCCCCGAGGACCTCGACCTGTGCGCGGCCGGCGGCGGCGACGGGCCGTCGCTGTCGGACGAGAACGACGAGGAGCTCTTCTCCATGTTCCTCGACGTGGAGAAGCTGAACAGCACGTGCGGGGCGTCGTCGGAGGCGGAGGCGGAGTCGTCGTCCGCCGGCGCCGCGGCGGCGGTGGCGGCGGCGGCCGCCGCCGCCGCCCATGGAGCGAGGCCGAAGCACCAGCACAGCCTGTCCATGGATGAGTCGATGTCGATCAAGGCTGAGGAGCTCGTCGGGGCGTCGCCCGGGACGGAGGGGATGTCGTCGGCGGAGGCCAAGAAGGCCGTGTCCGCGGCCAAGCTCGCCGAGCTTGCTCTCGTCGATCCCAAGAGGGCGAAAAGGATTTGGGCTAACAGACAATCTGCGGCAAGATCAAAGGAAAGGAAAATGCGATATATTGCTGAACTTGAGCGCAAGGTGCAAACCCTGCAAACAGAAGCAACAACACTGTCAGCCCAGTTGGCACTGCTACAGAGAGATACCAGTGGGCTAACTACTGAGAATAGTGAACTGAAGCTACGTCTGCAGACCATGGAGCAGCAAGTCCACTTGCAAGATGCTTTGAATGACACCCTGAAGTCTGAGGTTCAGCGGCTTAAGGTTGCAACCGGTCAAATGGCGAATGGTGGAGGGATGATGATGAACTTCGGTGGCATGCCACACCAATTCGGAGGCAACCAGCAGATGTTCCAGAACAACCAGGCCATGCAATCTATGCTGGCAGCACACCAGCTGCAACAGCTCCAGCTTCATCCTCAGGCTCAGCAGCAGCAGGTGCTGCACCCTCAGCATCAGCAGCAGCAGCCATTGCACCCTCTACAAGCGCAGCAGCTCCAGCAGGCGGCACGAGACCTCAAGATGAAATCGCCGATGGGCGGCCAGAGCCAGTGGGGAGATGGCAAGTCAGGAAGCAGCGGCAACTGATGCGTCATTTACAAATTTACAAAAAAATTCCCCAAAGTTTCGGTGTAAGGTTGTGGTTTAACAACCATGGAGATGGTCTGTTTCATTGAGATGATGATGATGTGCAAGAGTAGTTATCATCATCATCATCGGTAGGTTCAGGTTGGCTTCAGCTTCAGTCATACAGTTGGGTGGATGTTCAGTTGAAGAGTTTATCTGTAGCTGGTTCAGTAAGGAAATGGTCGAATAATCAAGAATTCCAGGTTAAAATCTTTCGTTTCTTTGGTAAGGTAGCACATCACCAAGATGTACTGTTGTAGTGTTGTCTACAGTTCCATAAATTCAAGTAGCCAGTATACGCTGTTGTTTAGTTTTTCTCCGGTTTTTTAGAGGTAGAGGCGTTTCTAGTGTTAATCGAGAGGTATACTGTATACCTTCTGATTAACATGTAAATCACTCAACACCTCTACCTCCATAAGGACCGGAGAAAAACTCAATTGTTTAATTAAGATGCCATTCATGACTAGATGTTCTCTGTCAGATGATCATATTGCACTCTGCTCCCTCTGCCTCATTAAAAAAAAATAAACCTAGCACACATGATGTGAGCGTC
CDS Sequence
- >LOC_Os09g34060.1
ATGAACAGGGAGAAATCCCCGATCCCGGGAGACGGCGGCGACGGGTTGCCGCCGCAGGCCACCCGCCGGGCGGGCCCTCCGGCGGCGGCGGCGGCGGCGGAGTACGACATCAGCCGCATGCCGGATTTCCCGACGAGGAACCCCGGCCACAGGCGCGCCCACTCCGAGATCCTGAGCCTCCCCGAGGACCTCGACCTGTGCGCGGCCGGCGGCGGCGACGGGCCGTCGCTGTCGGACGAGAACGACGAGGAGCTCTTCTCCATGTTCCTCGACGTGGAGAAGCTGAACAGCACGTGCGGGGCGTCGTCGGAGGCGGAGGCGGAGTCGTCGTCCGCCGGCGCCGCGGCGGCGGTGGCGGCGGCGGCCGCCGCCGCCGCCCATGGAGCGAGGCCGAAGCACCAGCACAGCCTGTCCATGGATGAGTCGATGTCGATCAAGGCTGAGGAGCTCGTCGGGGCGTCGCCCGGGACGGAGGGGATGTCGTCGGCGGAGGCCAAGAAGGCCGTGTCCGCGGCCAAGCTCGCCGAGCTTGCTCTCGTCGATCCCAAGAGGGCGAAAAGGATTTGGGCTAACAGACAATCTGCGGCAAGATCAAAGGAAAGGAAAATGCGATATATTGCTGAACTTGAGCGCAAGGTGCAAACCCTGCAAACAGAAGCAACAACACTGTCAGCCCAGTTGGCACTGCTACAGAGAGATACCAGTGGGCTAACTACTGAGAATAGTGAACTGAAGCTACGTCTGCAGACCATGGAGCAGCAAGTCCACTTGCAAGATGCTTTGAATGACACCCTGAAGTCTGAGGTTCAGCGGCTTAAGGTTGCAACCGGTCAAATGGCGAATGGTGGAGGGATGATGATGAACTTCGGTGGCATGCCACACCAATTCGGAGGCAACCAGCAGATGTTCCAGAACAACCAGGCCATGCAATCTATGCTGGCAGCACACCAGCTGCAACAGCTCCAGCTTCATCCTCAGGCTCAGCAGCAGCAGGTGCTGCACCCTCAGCATCAGCAGCAGCAGCCATTGCACCCTCTACAAGCGCAGCAGCTCCAGCAGGCGGCACGAGACCTCAAGATGAAATCGCCGATGGGCGGCCAGAGCCAGTGGGGAGATGGCAAGTCAGGAAGCAGCGGCAACTGA
Protein Sequence
- >LOC_Os09g34060.1
MNREKSPIPGDGGDGLPPQATRRAGPPAAAAAAEYDISRMPDFPTRNPGHRRAHSEILSLPEDLDLCAAGGGDGPSLSDENDEELFSMFLDVEKLNSTCGASSEAEAESSSAGAAAAVAAAAAAAAHGARPKHQHSLSMDESMSIKAEELVGASPGTEGMSSAEAKKAVSAAKLAELALVDPKRAKRIWANRQSAARSKERKMRYIAELERKVQTLQTEATTLSAQLALLQRDTSGLTTENSELKLRLQTMEQQVHLQDALNDTLKSEVQRLKVATGQMANGGGMMMNFGGMPHQFGGNQQMFQNNQAMQSMLAAHQLQQLQLHPQAQQQQVLHPQHQQQQPLHPLQAQQLQQAARDLKMKSPMGGQSQWGDGKSGSSGN*