Gene Details:

Functional Descriptions:

  • Suppression of OsRAD51D results in defects in reproductive development in rice (Oryza sativa L.).
  • Overall, these results suggest that OsRAD51D plays a critical role in reproductive growth in rice.
  • The OsRAD51D and Ubi:RNAi-OsRAD51D plants contained longer telomeres compared with wild type plants, indicating that OsRAD51D is a negative factor for telomere lengthening.
  • Homozygous OsRAD51D mutant flowers exhibited impaired development of lemma and palea and contained unusual numbers of stamens and stigmas.
  • During early meiosis, OsRAD51D pollen mother cells (PMCs) failed to form normal homologous chromosome pairings.
  • Here, through detailed analyses of OsRAD51D single and double mutants, we pinpoint the specific function of OsRAD51D in coordinating homologous pairing and recombination by preventing non-homologous interactions during meiosis.
  • Moreover, the interplay between OsRAD51D and OsRAD51C indicates both conservation and divergence of their functions in meiosis.
  • Altogether, this work reveals that OsRAD51D plays an essential role in the inhibition of non-homologous connections, thus guaranteeing faithful pairing and recombination during meiosis.
  • OsRAD51D promotes homologous pairing and recombination by preventing nonhomologous interactions in rice meiosis.
  • Here, through detailed analyses of OsRAD51D single and double mutants, we pinpoint the specific function of OsRAD51D in coordinating homologous pairing and recombination by preventing nonhomologous interactions during meiosis.
  • Altogether, this work reveals that OsRAD51D plays an essential role in the inhibition of nonhomologous connections, thus guaranteeing faithful pairing and recombination during meiosis.
  • The failed localization of OsRAD51 and OsDMC1 in OsRAD51D, together with the genetic analysis of OsRAD51D Osdmc1a Osdmc1b, indicates that OsRAD51D acts at a very early stage of homologous recombination.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >LOC_Os09g01680.1
    GCCACGCAACGCCGCTTCCCCTTCTGGCTGTAATGGCGATGGCGGCGACGTCGGCGAGCGGCGGCGCCGGCTGCTTCCCCAGGCCTCCTCCCTCCGGCGGCGAGGAGAAGAAGCAAGATGAGGAGGGGCAATGCTTTCTGGATGGAATGGACTTGCTCAAGGATGCGACGGAGAACAAGCGCTTCCTCCCCACGGGCCTTCAAGGCGTCGACGCGCTTCTTGGAGGCGGCCTGCGCCAAGGTCAGCTCACTGAAATAACCGGCCAATCGTCCTCCGGTAAAACACAGGTCTGTCTTTGTTCTGCTTCACATGTGGCAGCCAGGCAGTTGGGTGTTGTTATGTACTTGGATACTAGCAATTCCTTTTCCCCTAGCCGCATTGCTCGAATAGTTGATGGATTCCCCATCTCTTTGGTCAGAGAGCCAAAGAATGTGCGACTCGAGAGGGTCATGAGCAGCATCATTTGTAAGTCAGTCTTTGATATATTCGATTTGTTTGAAGTGCTACATCAACTTGAATTGTCACTGAAGAGCAAGGTAAACAATGGGGGTAACAAGATATGCTTGCTTATCATTGACTCAATATCGTCTATACTTGCTCCCATCAACGGTGGGAAGTATCCACGAGGGCGATCGATGATGATATCAGTGGCTATGATTCTAAAGAAGCTAGCATATGAGCATAATCTATCTGTTCTGGTTACTAACCATATGGTTGCTGGGAATGGAGCTCCCAAGCCTGCTCTTGGTGAGAGCTGGAAAACTGTTCCACATGTCCGCTTGGTGATATCTCGTGAGCGTGGTAGCAAAATCTGCGCAGCAACTGTGCTGAAGCACACACTACTGGCTTCGGGCCGTGTTATGAAATTTGCCGTACCAAGCTGAATTCAGCAACTTGATGCTTCATATATAACCAGAAGGGAACTGATCTTTGTAGTTCAAGCTATAGAAAGAACTTCACCCGTAAGGGTAACCTTTTGATTTACCTTGGCTTTATGTTCCAGGCCATTTGTATATTAATCCAATGGTTTTTGCATGTTGCCTGCGTCCGTGGTATCACGCTTAACTGATCCATATATATAGTTTCTTGGTAAACTGAATGTATCAGAAACATTCAGTTTTCAAGTTTTTGTTTCTTCAATTATTCACTGTGAATACTGGAAAATGGTAGTTTCCCATCAGTGGATAAAATTGAATGAAATTATATTTGTTCCTTGTTTTC
  • >LOC_Os09g01680.2
    GCCACGCAACGCCGCTTCCCCTTCTGGCTGTAATGGCGATGGCGGCGACGTCGGCGAGCGGCGGCGCCGGCTGCTTCCCCAGGCCTCCTCCCTCCGGCGGCGAGGAGAAGAAGCAAGATGAGGAGGGGCAATGCTTTCTGGATGGAATGGACTTGCTCAAGGATGCGACGGAGAACAAGCGCTTCCTCCCCACGGGCCTTCAAGGCGTCGACGCGCTTCTTGGAGGCGGCCTGCGCCAAGGTCAGCTCACTGAAATAACCGGCCAATCGTCCTCCGGTAAAACACAGGTCTGTCTTTGTTCTGCTTCACATGTGGCAGCCAGGCAGTTGGGTGTTGTTATGTACTTGGATACTAGCAATTCCTTTTCCCCTAGCCGCATTGCTCGAATAGTTGATGGATTCCCCATCTCTTTGGTCAGAGAGCCAAAGAATGTGCGACTCGAGAGGGTCATGAGCAGCATCATTTGTAAGTCAGTCTTTGATATATTCGATTTGTTTGAAGTGCTACATCAACTTGAATTGTCACTGAAGAGCAAGGTAAACAATGGGGGTAACAAGATATGCTTGCTTATCATTGACTCAATATCGTCTATACTTGCTCCCATCAACGGTGGGAAGTATCCACGAGGGCGATCGATGATGATATCAGTGGCTATGATTCTAAAGAAGCTAGCATATGAGCATAATCTATCTGTTCTGGTTACTAACCATATGGTTGCTGGGAATGGAGCTCCCAAGCCTGCTCTTGGTGAGAGCTGGAAAACTGTTCCACATGTCCGCTTGGTGATATCTCGTGAGCGTGGTAGCAAAATCTGCGCAGCAACTGTGCTGAAGCACACACTACTGGCTTCGGGCCGTGTTATGAAATTTGCCGTACCAAGCTGAATTCAGCAACTTGATGCTTCATATATAACCAGAAGGGAACTGATCTTTGTAGTTCAAGCTATAGAAAGAACTTCACCCGTAAGGGTAACCTTTTGATTTACCTTGGCTTTATGTTCCAGGCCATTTGTATATTAATCCAATGGTTTTTGCATGTTGCCTGCGTCCGTGGTATCACGCTTAACTGATCCATATATATAGTTTCTTGGTAAACTGAATGTATCAGAAACATTCAGTTTTCAAGTTTTTGTTTCTTCAATTATTCACTGTGAATACTGGAAAATGGTAGTTTCCCATCAGTGGATAAAATTGAATGAAATTATATTTGTTCCTTGTTTTC
  • >LOC_Os09g01680.3
    GCCACGCAACGCCGCTTCCCCTTCTGGCTGTAATGGCGATGGCGGCGACGTCGGCGAGCGGCGGCGCCGGCTGCTTCCCCAGGCCTCCTCCCTCCGGCGGCGAGGAGAAGAAGCAAGATGAGGAGGGGCAATGCTTTCTGGATGGAATGGACTTGCTCAAGGATGCGACGGAGAACAAGCGCTTCCTCCCCACGGGCCTTCAAGGCGTCGACGCGCTTCTTGGAGGCGGCCTGCGCCAAGGTCAGCTCACTGAAATAACCGGCCAATCGTCCTCCGGTAAAACACAGGTCTGTCTTTGTTCTGCTTCACATGTGGCAGCCAGGCAGTTGGGTGTTGTTATGTACTTGGATACTAGCAATTCCTTTTCCCCTAGCCGCATTGCTCGAATAGTTGATGGATTCCCCATCTCTTTGGTCAGAGAGCCAAAGAATGTGCGACTCGAGAGGGTCATGAGCAGCATCATTTGTAAGTCAGTCTTTGATATATTCGATTTGTTTGAAGTGCTACATCAACTTGAATTGTCACTGAAGAGCAAGGTAAACAATGGGGGTAACAAGATATGCTTGCTTATCATTGACTCAATATCGTCTATACTTGCTCCCATCAACGGTGGGAAGTATCCACGAGGGCGATCGATGATGATATCAGTGGCTATGATTCTAAAGAAGCTAGCATATGAGCATAATCTATCTGTTCTGGTTACTAACCATATGGTTGCTGGGAATGGAGCTCCCAAGCCTGCTCTTGGTGAGAGCTGGAAAACTGTTCCACATGTCCGCTTGGTGATATCTCGTGAGCGTGGTAGCAAAATCTGCGCAGCAACTGTGCTGAAGCACACACTACTGGCTTCGGGCCGTGTTATGAAATTTGCCGTACCAAGCTGAATTCAGCAACTTGATGCTTCATATATAACCAGAAGGGAACTGATCTTTGTAGTTCAAGCTATAGAAAGAACTTCACCCGTAAGGGTAACCTTTTGATTTACCTTGGCTTTATGTTCCAGGCCATTTGTATATTAATCCAATGGTTTTTGCATGTTGCCTGCGTCCGTGGTATCACGCTTAACTGATCCATATATATAGTTTCTTGGTAAACTGAATGTATCAGAAACATTCAGTTTTCAAGTTTTTGTTTCTTCAATTATTCACTGTGAATACTGGAAAATGGTAGTTTCCCATCAGTGGATAAAATTGAATGAAATTATATTTGTTCCTTGTTTTC
CDS Sequence
  • >LOC_Os09g01680.1
    ATGGCGATGGCGGCGACGTCGGCGAGCGGCGGCGCCGGCTGCTTCCCCAGGCCTCCTCCCTCCGGCGGCGAGGAGAAGAAGCAAGATGAGGAGGGGCAATGCTTTCTGGATGGAATGGACTTGCTCAAGGATGCGACGGAGAACAAGCGCTTCCTCCCCACGGGCCTTCAAGGCGTCGACGCGCTTCTTGGAGGCGGCCTGCGCCAAGGTCAGCTCACTGAAATAACCGGCCAATCGTCCTCCGGTAAAACACAGGTCTGTCTTTGTTCTGCTTCACATGTGGCAGCCAGGCAGTTGGGTGTTGTTATGTACTTGGATACTAGCAATTCCTTTTCCCCTAGCCGCATTGCTCGAATAGTTGATGGATTCCCCATCTCTTTGGTCAGAGAGCCAAAGAATGTGCGACTCGAGAGGGTCATGAGCAGCATCATTTGTAAGTCAGTCTTTGATATATTCGATTTGTTTGAAGTGCTACATCAACTTGAATTGTCACTGAAGAGCAAGGTAAACAATGGGGGTAACAAGATATGCTTGCTTATCATTGACTCAATATCGTCTATACTTGCTCCCATCAACGGTGGGAAGTATCCACGAGGGCGATCGATGATGATATCAGTGGCTATGATTCTAAAGAAGCTAGCATATGAGCATAATCTATCTGTTCTGGTTACTAACCATATGGTTGCTGGGAATGGAGCTCCCAAGCCTGCTCTTGGTGAGAGCTGGAAAACTGTTCCACATGTCCGCTTGGTGATATCTCGTGAGCGTGGTAGCAAAATCTGCGCAGCAACTGTGCTGAAGCACACACTACTGGCTTCGGGCCGTGTTATGAAATTTGCCGTACCAAGCTGA
  • >LOC_Os09g01680.2
    ATGGCGATGGCGGCGACGTCGGCGAGCGGCGGCGCCGGCTGCTTCCCCAGGCCTCCTCCCTCCGGCGGCGAGGAGAAGAAGCAAGATGAGGAGGGGCAATGCTTTCTGGATGGAATGGACTTGCTCAAGGATGCGACGGAGAACAAGCGCTTCCTCCCCACGGGCCTTCAAGGCGTCGACGCGCTTCTTGGAGGCGGCCTGCGCCAAGGTCAGCTCACTGAAATAACCGGCCAATCGTCCTCCGGTAAAACACAGGTCTGTCTTTGTTCTGCTTCACATGTGGCAGCCAGGCAGTTGGGTGTTGTTATGTACTTGGATACTAGCAATTCCTTTTCCCCTAGCCGCATTGCTCGAATAGTTGATGGATTCCCCATCTCTTTGGTCAGAGAGCCAAAGAATGTGCGACTCGAGAGGGTCATGAGCAGCATCATTTGTAAGTCAGTCTTTGATATATTCGATTTGTTTGAAGTGCTACATCAACTTGAATTGTCACTGAAGAGCAAGGTAAACAATGGGGGTAACAAGATATGCTTGCTTATCATTGACTCAATATCGTCTATACTTGCTCCCATCAACGGTGGGAAGTATCCACGAGGGCGATCGATGATGATATCAGTGGCTATGATTCTAAAGAAGCTAGCATATGAGCATAATCTATCTGTTCTGGTTACTAACCATATGGTTGCTGGGAATGGAGCTCCCAAGCCTGCTCTTGGTGAGAGCTGGAAAACTGTTCCACATGTCCGCTTGGTGATATCTCGTGAGCGTGGTAGCAAAATCTGCGCAGCAACTGTGCTGAAGCACACACTACTGGCTTCGGGCCGTGTTATGAAATTTGCCGTACCAAGCTGA
  • >LOC_Os09g01680.3
    ATGGCGATGGCGGCGACGTCGGCGAGCGGCGGCGCCGGCTGCTTCCCCAGGCCTCCTCCCTCCGGCGGCGAGGAGAAGAAGCAAGATGAGGAGGGGCAATGCTTTCTGGATGGAATGGACTTGCTCAAGGATGCGACGGAGAACAAGCGCTTCCTCCCCACGGGCCTTCAAGGCGTCGACGCGCTTCTTGGAGGCGGCCTGCGCCAAGGTCAGCTCACTGAAATAACCGGCCAATCGTCCTCCGGTAAAACACAGGTCTGTCTTTGTTCTGCTTCACATGTGGCAGCCAGGCAGTTGGGTGTTGTTATGTACTTGGATACTAGCAATTCCTTTTCCCCTAGCCGCATTGCTCGAATAGTTGATGGATTCCCCATCTCTTTGGTCAGAGAGCCAAAGAATGTGCGACTCGAGAGGGTCATGAGCAGCATCATTTGTAAGTCAGTCTTTGATATATTCGATTTGTTTGAAGTGCTACATCAACTTGAATTGTCACTGAAGAGCAAGGTAAACAATGGGGGTAACAAGATATGCTTGCTTATCATTGACTCAATATCGTCTATACTTGCTCCCATCAACGGTGGGAAGTATCCACGAGGGCGATCGATGATGATATCAGTGGCTATGATTCTAAAGAAGCTAGCATATGAGCATAATCTATCTGTTCTGGTTACTAACCATATGGTTGCTGGGAATGGAGCTCCCAAGCCTGCTCTTGGTGAGAGCTGGAAAACTGTTCCACATGTCCGCTTGGTGATATCTCGTGAGCGTGGTAGCAAAATCTGCGCAGCAACTGTGCTGAAGCACACACTACTGGCTTCGGGCCGTGTTATGAAATTTGCCGTACCAAGCTGA
Protein Sequence
  • >LOC_Os09g01680.1
    MAMAATSASGGAGCFPRPPPSGGEEKKQDEEGQCFLDGMDLLKDATENKRFLPTGLQGVDALLGGGLRQGQLTEITGQSSSGKTQVCLCSASHVAARQLGVVMYLDTSNSFSPSRIARIVDGFPISLVREPKNVRLERVMSSIICKSVFDIFDLFEVLHQLELSLKSKVNNGGNKICLLIIDSISSILAPINGGKYPRGRSMMISVAMILKKLAYEHNLSVLVTNHMVAGNGAPKPALGESWKTVPHVRLVISRERGSKICAATVLKHTLLASGRVMKFAVPS*
  • >LOC_Os09g01680.2
    MAMAATSASGGAGCFPRPPPSGGEEKKQDEEGQCFLDGMDLLKDATENKRFLPTGLQGVDALLGGGLRQGQLTEITGQSSSGKTQVCLCSASHVAARQLGVVMYLDTSNSFSPSRIARIVDGFPISLVREPKNVRLERVMSSIICKSVFDIFDLFEVLHQLELSLKSKVNNGGNKICLLIIDSISSILAPINGGKYPRGRSMMISVAMILKKLAYEHNLSVLVTNHMVAGNGAPKPALGESWKTVPHVRLVISRERGSKICAATVLKHTLLASGRVMKFAVPS*
  • >LOC_Os09g01680.3
    MAMAATSASGGAGCFPRPPPSGGEEKKQDEEGQCFLDGMDLLKDATENKRFLPTGLQGVDALLGGGLRQGQLTEITGQSSSGKTQVCLCSASHVAARQLGVVMYLDTSNSFSPSRIARIVDGFPISLVREPKNVRLERVMSSIICKSVFDIFDLFEVLHQLELSLKSKVNNGGNKICLLIIDSISSILAPINGGKYPRGRSMMISVAMILKKLAYEHNLSVLVTNHMVAGNGAPKPALGESWKTVPHVRLVISRERGSKICAATVLKHTLLASGRVMKFAVPS*