Gene Details:

• MSU gene ID: LOC_Os08g39250
• RAPdb gene ID: Os08g0502000
• Gene Symbol: OsEDM2L
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• OsEDM2L interacts with the transcription factors bHLH142 and TAPETUM DEGENERATION RETARDATION to regulate the expression of ETERNAL TAPETUM 1 (EAT1), a positive regulator of tapetal PCD.
• The OsEDM2L knockout mutant showed delayed tapetal programmed cell death (PCD) and defective pollen development.
• Therefore, OsEDM2L is indispensable for proper mRNA m6 A modification in rice anther development.
• OsEDM2L mediates m 6 A of EAT1 transcript for proper alternative splicing and polyadenylation regulating rice tapetal degradation.
• Mutation of OsEDM2L altered the transcriptomic m6 A landscape, and caused a distinct m6 A modification of the EAT1 transcript leading to dysregulation of its alternative splicing and polyadenylation, followed by suppression of the EAT1 target genes OsAP25 and OsAP37 for tapetal PCD.

Function-related keywords:

• transcription-factor ,  development ,  pollen ,  anther ,  cell-death ,  anther-development ,  tapetum ,  tapetal ,  tapetum-degeneration ,  pollen-development ,  PCD ,  tapetal-programmed-cell-death ,  programmed-cell-death

Literature:

• OsEDM2L mediates m6 A of EAT1 transcript for proper alternative splicing and polyadenylation regulating rice tapetal degradation .  DOI:  10.1111/jipb.13167 ;  PMID:  34449974

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: