Gene Details:
- MSU gene ID: LOC_Os08g05840
- RAPdb gene ID: Os08g0154600
- Gene Symbol: OsTOP1
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Here we showed that knockdown of OsTOP1 strongly affects rice development, causing defects in root architecture and gravitropism which are the consequences of mis-regulation of auxin signaling and transporter genes.
- Our data reveals R-loops as important factors in polar auxin transport and plant root development, and highlights that OsTOP1 functions as a key to link transcriptional R-loops and plant hormone signaling.
Function-related keywords:
Literature:
- DNA Topoisomerase 1 Prevents R-loop Accumulation to Modulate Auxin-Regulated Root Development in Rice . DOI: 10.1016/j.molp.2017.04.001 ; PMID: 28412545
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os08g05840.1
AAGAGAAAAAAAACGCAAGGCGAGAGAGGGAGGGAGAGGAGTCGGAGGCAGCGGCGCGGGCGAGGCGAGGTGAGAGCGAGCGATAGAAATACGAGAGCGGGAGGAGAGGCGAGGAGAGAGAGACACAGATAAGCTCAGCCCTAACCCTAGCTCCCCGCCTCGCCGCCGCCGCCGCCGCCGCCGCCGCACCGCTCCCCGGGGAGCGGGACGTCGCCGCCGCGGCGCCTAGGTGTGGTTGACTCAGCATATTTGTTCCGTCTGCCAGCCGCCGCCCCTAGGGATCGATGGCTGTTGTCGATCCTGTTATGTTTGACAACGACGACGAGGAAGGTCCGATCTCCTTCAAGAGGTCGAGCACCTCTGTGAAGAACAGGCCCACCCCCACAAAGCAGGAGGGCTCATCAGGGAATGCCGGACCTATTAGGAGCCCTAAGGCTGTTGCTTCCAATCAACAGAAGAATGGGCTGACTGGTGTTTCGAGGCCTTTGCAACAGAGGCCGCAGTCAAGCAGTCCAAACCCTCGACCTTTGGGATCAGGTCAGCCGAACAGTTCCAAAGAACATAGTAGCCATAATAGTAACTCAGTGGATAAGAGTAAATTGAAAAGACCTTTCGTGGAAGATAAGTCGGATGACTCAGAAGATGACCATAAGCCAATCGGATTAAGGAGAAAGGTCGAGGATAGAAATTTGAAGAAACCTGCTGTAGGAAGTGGGACAGCAAATGATTCAGATGATGATAAACCATTGAGTCTCAAGATAAACTCAACAAAAACGCCTTCGAGTAGTGCAAATAAGGCTATTGTACTGAAAACTACACCTAAAATTGAGCAACCTGGTGATGATTCAGAGGACGATAAACCACTGGCCAGCAGGTTGCCAACTAATGCTGCTCTGAAAAGGGGAGGTAATGTTTCTGATGATTCAGAGGATGAGAAGCCATTGGCTGCCCGATTTTCGAAAGTTACTGGCAATGCATCTGCAAGTATCTCAAGTTCAAAGGACAAGGTCCTGTCTGCAAGTATAAAAGCAAGTTCTTCCAGCAAGATGTCTAACAATGACGCGAGCACATCACGAAATTCAATTAAAAGGCCAATTGACAATAATAATCAAACAAGTTCAGCTCTCAAGAAGGCGAGGCCTTCAGATGTTTCTGCGTCTGCAAGTGTCAAAAGAGAACCCAAGGCGGATGACAATGACAATGTACCTCTTTCACAAAGACTGAAAATGGGTGAGTCTTCAAAAAGCAAGCCACCTGCAAAGAATATCGTAAAGAAGAGTCCTTCATCTTTAAAGAAGGACAACAAGAAAATGAAAATGAAAATGAAAACAAAGAAAACAATGAAAAATTCTCAGTTCTCAAAGACAATGAAGGTCCCTCCTGGATCTGGTGGTGGACAGAAATGGACTACCTTGGTGCACAGTGGTGTTATTTTCCCCCCTCCATACAAGCCTCATGGTGTCAAGATGCTTTACAACGGGCAACCTGTTGATCTGACGCCAGAACAAGAAGAGGTTGCCACCATGTTTGCTGTGATGAAAGACACTGATTATGCATCCAAGCAAACATTCATTGACAACTTCTTCACTGATTGGAGAAAAATTCTTGGTAAAAACCATGTCATCAAGAAATTTGAGCTTTGTGATTTCACCCCGATCTATGAATGGCACCTAAGAGAGAAGGAGAAGAAGAAGCAGATGACATCTGAGGAGAAGAAAGCATTGAAGGAAGAGAAATTGAAACAAGAGGAGAAGTACATGTGGGCTATTGTAGATGGTGTTAAAGAGAAGGTTGGCAATTTCAGAGTAGAACCACCTGGCTTGTTCAGGGGGCGCGGAGAGCATCCGAAGATGGGAAAACTGAAGCGCCGCATTAAACCAAGCGATATTACAATAAATATCGGAAAAGGGGCTCCGATCCCCGAATGTCCCATACCTGGAGAAAGTTGGAAAGAAGTCAAACACGACAACACAGTTACATGGTTGGCCTTTTGGAATGATCCAATAAGCCAAAAAGATTTCAAGTATGTTTTCTTGGCAGCAAGCAGTGCATTAAAGGGCCAAAGTGACAAAGAGAAGTATGAGAAGTCTCGAAAATTGAAGCATCACGTACACAAAATTCGTGACACTTACACAAAGGATTTCAGAAGCAAAGATAAGACAAAGAAACAAATTGCAGTGGCAACATACCTTATAGATAAGTTAGCCCTTAGGGCAGGCAATGAGAAGGATGAAGATGAGGCTGAAACTGTTGGTTGCTGTACACTGAAGGTTGATAATGTTACTTGTGTTCCTCCAAATAAACTGCAGTTCGACTTCCTTGGTAAAGATTCTATAAGATACTTCAATACTGTAGAGGTTGAACTGCTTGTATACAAGGCAATTGAGGAATTCCGTGCTGGCAAGAAACCAGGACAAGATCTCTTTGACAAACTCGATACAACCAGGCTAAATGCTCATCTAAAGGACTTGATGCCTGGGCTTACCGCAAAAGTGTTCCGTACATATAATGCTTCAATCACCTTGGATGATATTTTGCACAAAGAAACAGAAGATGGAACTCTTCTTGAAAAAATTGCGGTTTATCAACGAGCCAACAAAGAGGTTGCTATAATCTGTAACCATCAGCGTAGTGTCTCAAAATCACATGATTCCCAGATGACTAGATTGAATGAGAAGATTGATGAATTGAAGGCCCAAAGGGATGAATTGAAGGCAGACTTGAGCAAAGTAAGGAAAGGAAAGAATCTAGGCAATGACAAAGATGGGAAACCAAAAAGAAATTTGGCCCCTGAAGCGTTTGAAAAGAAGATATCTCAGATTGAAACCAAGATAGAGAAGATGGAGATGGATAAGAAGATTAAAGAGGATTTAAAGACAGTGGCACTAGGAACTTCAAAGATCAATTACCTTGATCCCAGAATTACTGTTGCATGGTGCAAACGCCATGAAGTACCCATCGAGAAGATTTTCAACAAATCACTCATTGCGAAATTTTCGTGGGCAATGGACGTCGACCCGGATTTCAGATTTTAAGAGGGTACAAGAGCATTGGCTACTGGTCATCCGGCCTGTAGTAAAGTTGATCCAGCTTCCAGTCCTTGTCCCGGACACTAATTTGCAGCTAGGAAAGGAAGAGCTCGGTGTTTGTTTTTGAAGTCCCCTGCTCCTGGAAAGAAGGAAGCACCCGGCATTCTCATTGTAGGCTTTTTTTTTCTTTTACTACTTGTTGGTGCCTTTGCCATCGGTCCTCAAGTTCTGTATGCATTTGGGCTGAGGAATTTTAGCTCGCTGAGAACGAATGGACATTCATTTTATACCGAATTAATCTCAAATATACCATGAGGTTTCGTTTGGTTGCGGAAGGGAACATTGTTTGCGTATGTACTTGCGAACTGGTAATGGAAGAAGTGCTGAGGTGTAAATTTTGATCAAAGATATTTTTCCTG
CDS Sequence
- >LOC_Os08g05840.1
ATGGCTGTTGTCGATCCTGTTATGTTTGACAACGACGACGAGGAAGGTCCGATCTCCTTCAAGAGGTCGAGCACCTCTGTGAAGAACAGGCCCACCCCCACAAAGCAGGAGGGCTCATCAGGGAATGCCGGACCTATTAGGAGCCCTAAGGCTGTTGCTTCCAATCAACAGAAGAATGGGCTGACTGGTGTTTCGAGGCCTTTGCAACAGAGGCCGCAGTCAAGCAGTCCAAACCCTCGACCTTTGGGATCAGGTCAGCCGAACAGTTCCAAAGAACATAGTAGCCATAATAGTAACTCAGTGGATAAGAGTAAATTGAAAAGACCTTTCGTGGAAGATAAGTCGGATGACTCAGAAGATGACCATAAGCCAATCGGATTAAGGAGAAAGGTCGAGGATAGAAATTTGAAGAAACCTGCTGTAGGAAGTGGGACAGCAAATGATTCAGATGATGATAAACCATTGAGTCTCAAGATAAACTCAACAAAAACGCCTTCGAGTAGTGCAAATAAGGCTATTGTACTGAAAACTACACCTAAAATTGAGCAACCTGGTGATGATTCAGAGGACGATAAACCACTGGCCAGCAGGTTGCCAACTAATGCTGCTCTGAAAAGGGGAGGTAATGTTTCTGATGATTCAGAGGATGAGAAGCCATTGGCTGCCCGATTTTCGAAAGTTACTGGCAATGCATCTGCAAGTATCTCAAGTTCAAAGGACAAGGTCCTGTCTGCAAGTATAAAAGCAAGTTCTTCCAGCAAGATGTCTAACAATGACGCGAGCACATCACGAAATTCAATTAAAAGGCCAATTGACAATAATAATCAAACAAGTTCAGCTCTCAAGAAGGCGAGGCCTTCAGATGTTTCTGCGTCTGCAAGTGTCAAAAGAGAACCCAAGGCGGATGACAATGACAATGTACCTCTTTCACAAAGACTGAAAATGGGTGAGTCTTCAAAAAGCAAGCCACCTGCAAAGAATATCGTAAAGAAGAGTCCTTCATCTTTAAAGAAGGACAACAAGAAAATGAAAATGAAAATGAAAACAAAGAAAACAATGAAAAATTCTCAGTTCTCAAAGACAATGAAGGTCCCTCCTGGATCTGGTGGTGGACAGAAATGGACTACCTTGGTGCACAGTGGTGTTATTTTCCCCCCTCCATACAAGCCTCATGGTGTCAAGATGCTTTACAACGGGCAACCTGTTGATCTGACGCCAGAACAAGAAGAGGTTGCCACCATGTTTGCTGTGATGAAAGACACTGATTATGCATCCAAGCAAACATTCATTGACAACTTCTTCACTGATTGGAGAAAAATTCTTGGTAAAAACCATGTCATCAAGAAATTTGAGCTTTGTGATTTCACCCCGATCTATGAATGGCACCTAAGAGAGAAGGAGAAGAAGAAGCAGATGACATCTGAGGAGAAGAAAGCATTGAAGGAAGAGAAATTGAAACAAGAGGAGAAGTACATGTGGGCTATTGTAGATGGTGTTAAAGAGAAGGTTGGCAATTTCAGAGTAGAACCACCTGGCTTGTTCAGGGGGCGCGGAGAGCATCCGAAGATGGGAAAACTGAAGCGCCGCATTAAACCAAGCGATATTACAATAAATATCGGAAAAGGGGCTCCGATCCCCGAATGTCCCATACCTGGAGAAAGTTGGAAAGAAGTCAAACACGACAACACAGTTACATGGTTGGCCTTTTGGAATGATCCAATAAGCCAAAAAGATTTCAAGTATGTTTTCTTGGCAGCAAGCAGTGCATTAAAGGGCCAAAGTGACAAAGAGAAGTATGAGAAGTCTCGAAAATTGAAGCATCACGTACACAAAATTCGTGACACTTACACAAAGGATTTCAGAAGCAAAGATAAGACAAAGAAACAAATTGCAGTGGCAACATACCTTATAGATAAGTTAGCCCTTAGGGCAGGCAATGAGAAGGATGAAGATGAGGCTGAAACTGTTGGTTGCTGTACACTGAAGGTTGATAATGTTACTTGTGTTCCTCCAAATAAACTGCAGTTCGACTTCCTTGGTAAAGATTCTATAAGATACTTCAATACTGTAGAGGTTGAACTGCTTGTATACAAGGCAATTGAGGAATTCCGTGCTGGCAAGAAACCAGGACAAGATCTCTTTGACAAACTCGATACAACCAGGCTAAATGCTCATCTAAAGGACTTGATGCCTGGGCTTACCGCAAAAGTGTTCCGTACATATAATGCTTCAATCACCTTGGATGATATTTTGCACAAAGAAACAGAAGATGGAACTCTTCTTGAAAAAATTGCGGTTTATCAACGAGCCAACAAAGAGGTTGCTATAATCTGTAACCATCAGCGTAGTGTCTCAAAATCACATGATTCCCAGATGACTAGATTGAATGAGAAGATTGATGAATTGAAGGCCCAAAGGGATGAATTGAAGGCAGACTTGAGCAAAGTAAGGAAAGGAAAGAATCTAGGCAATGACAAAGATGGGAAACCAAAAAGAAATTTGGCCCCTGAAGCGTTTGAAAAGAAGATATCTCAGATTGAAACCAAGATAGAGAAGATGGAGATGGATAAGAAGATTAAAGAGGATTTAAAGACAGTGGCACTAGGAACTTCAAAGATCAATTACCTTGATCCCAGAATTACTGTTGCATGGTGCAAACGCCATGAAGTACCCATCGAGAAGATTTTCAACAAATCACTCATTGCGAAATTTTCGTGGGCAATGGACGTCGACCCGGATTTCAGATTTTAA
Protein Sequence
- >LOC_Os08g05840.1
MAVVDPVMFDNDDEEGPISFKRSSTSVKNRPTPTKQEGSSGNAGPIRSPKAVASNQQKNGLTGVSRPLQQRPQSSSPNPRPLGSGQPNSSKEHSSHNSNSVDKSKLKRPFVEDKSDDSEDDHKPIGLRRKVEDRNLKKPAVGSGTANDSDDDKPLSLKINSTKTPSSSANKAIVLKTTPKIEQPGDDSEDDKPLASRLPTNAALKRGGNVSDDSEDEKPLAARFSKVTGNASASISSSKDKVLSASIKASSSSKMSNNDASTSRNSIKRPIDNNNQTSSALKKARPSDVSASASVKREPKADDNDNVPLSQRLKMGESSKSKPPAKNIVKKSPSSLKKDNKKMKMKMKTKKTMKNSQFSKTMKVPPGSGGGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYASKQTFIDNFFTDWRKILGKNHVIKKFELCDFTPIYEWHLREKEKKKQMTSEEKKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIKPSDITINIGKGAPIPECPIPGESWKEVKHDNTVTWLAFWNDPISQKDFKYVFLAASSALKGQSDKEKYEKSRKLKHHVHKIRDTYTKDFRSKDKTKKQIAVATYLIDKLALRAGNEKDEDEAETVGCCTLKVDNVTCVPPNKLQFDFLGKDSIRYFNTVEVELLVYKAIEEFRAGKKPGQDLFDKLDTTRLNAHLKDLMPGLTAKVFRTYNASITLDDILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHDSQMTRLNEKIDELKAQRDELKADLSKVRKGKNLGNDKDGKPKRNLAPEAFEKKISQIETKIEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKFSWAMDVDPDFRF*