Gene Details:

• MSU gene ID: LOC_Os07g49400
• RAPdb gene ID: Os07g0694700
• Gene Symbol: OsAPX2 APXb
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Loss of function in OsAPX2 affected the growth and development of rice seedlings, resulting in semi-dwarf seedlings, yellow-green leaves, leaf lesion mimic and seed sterility.
• Taken together, the cytosolic ascorbate peroxidase OsAPX2 plays an important role in rice growth and development by protecting the seedlings from abiotic stresses through scavenging reactive oxygen species.
• Gene knockout study reveals that cytosolic ascorbate peroxidase 2(OsAPX2) plays a critical role in growth and reproduction in rice under drought, salt and cold stresses.
• In this report, we studied the function of OsAPX2 gene using a T-DNA knockout mutant under the treatment of drought, salt and cold stresses.
• OsAPX2 expression was developmental- and spatial-regulated, and was induced by drought, salt, and cold stresses.
• Importance of ascorbate peroxidases OsAPX1 and OsAPX2 in the rice pathogen response pathways and growth and reproduction revealed by their transcriptional profiling.
• OsAPX2 mutants had lower APX activity and were sensitive to abiotic stresses; overexpression of OsAPX2 increased APX activity and enhanced stress tolerance.
• Loss of OsAPX2 altered rice architecture including shoot height and leaf inclination, resulting in shoot dwarfing, leaf dispersion and fertility decline.
• Additionally, the OsAPX2 conformational changes could be regulated by salt and heat stresses and these stimulated OsAPX2 dissociation and association, respectively.

Function-related keywords:

• leaf ,  growth ,  sterility ,  salt ,  cold-stress ,  seedling ,  drought ,  seed ,  abiotic-stress ,  dwarf ,  shoot ,  architecture ,  height ,  fertility

Literature:

• Involvement of hydrogen peroxide in heat shock- and cadmium-induced expression of ascorbate peroxidase and glutathione reductase in leaves of rice seedlings .  DOI:  10.1016/j.jplph.2011.11.012 ;  PMID:  22196946
• Importance of ascorbate peroxidases OsAPX1 and OsAPX2 in the rice pathogen response pathways and growth and reproduction revealed by their transcriptional profiling .  DOI:  10.1016/j.gene.2003.08.017 ;  PMID:  14644501
• Gene knockout study reveals that cytosolic ascorbate peroxidase 2(OsAPX2) plays a critical role in growth and reproduction in rice under drought, salt and cold stresses .  DOI:  10.1371/journal.pone.0057472 ;  PMID:  23468992
• Genetic transformation and analysis of rice OsAPx2 gene in Medicago sativa .  DOI:  10.1371/journal.pone.0041233 ;  PMID:  22848448
• Purification and characterization of two ascorbate peroxidases of rice (Oryza sativa L.) expressed in Escherichia coli .  DOI:  10.1007/s10529-004-6587-0 ;  PMID:  15685422
• Cytosolic APX2 is a pleiotropic protein involved in H2O2 homeostasis, chloroplast protection, plant architecture and fertility maintenance .  DOI:  10.1007/s00299-018-2272-y ;  PMID:  29549445
• Functional switching of ascorbate peroxidase 2 of rice (OsAPX2) between peroxidase and molecular chaperone .  DOI:  10.1038/s41598-018-27459-1 ;  PMID:  29907832

Related News:

Gene Resources:

• NCBI ID: AB053297
• UniProt accessions:

Sequences: