Gene Details:

Functional Descriptions:

  • Although the homologs can faithfully separate from each other at the end of meiosis I, the uncorrected merotelic attachment of paired sister kinetochores at the early stage of metaphase I in BRK1 reduces the tension across homologous kinetochores, causes the metaphase I spindle to be aberrantly shaped, and subsequently affects the synchronicity of homolog separation at the onset of anaphase I.
  • BRK1, a Bub1-related kinase, is essential for generating proper tension between homologous kinetochores at metaphase I of rice meiosis.
  • The BRK1 mutants are sterile due to the precocious separation of sister chromatids at the onset of anaphase I.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
  • >LOC_Os07g32480.1
    AACCTATTTTGCTGGATCCATGGTCTGAGTCTACTATGAATAATTTATTGGAGAACATTAATGTTGATCTGAAGAAGTTCGCTGGCTATCATAAGAGCAATAAGGTCTATCATGGAAAGGTGCCATTAACTTCGCCTCAGAATGTTTTAAGAAACAAAGTCATTGAATTAGGTGGTAGAAAGTACCAGATCAAAGGTTCTCCTGGTACTGGTGCTTTTGCAAAAGTTTACAAAGCCAGTGTCGATGGTAATACAGAAGACCTGGTTGCTTTAAAGATTCAGAAACCACCATTTCCTTGGGAATTTTACATGTATCGCCAGCTTGATACGCGCGTATCTGATATTGAGAGACCAAGCTTTGGCTACACTCATGAAGTGCATGTATACGCTGATGTCAGTGTGCTTGTTTGTGATTACCTGCCATACGGAACTCTTCTGGATGTTATAAATTCTCATCTAGTACTTGAACGCCATATGGATGAAGTTCTATGCATATATTACACTATAGAGATGCTGCGCATGTTGGAAACACTGCACAGCGTTGGCATAATTCATGGTGATTTCAAGCCTGACAATATGCTTGTTTGCTACCCAAGTGGAGAAATCACAGACGAAACCTTCAAAGGCGAGACAAGATCCGAGCGGAATCAGGGGCTCTGCCTTGTTGACTGGGGCCGTGGCATCGACCTGAACCTCTTCCCATCCGGTGCGGAGTTCTACGGCGACTGCCGAACCTCCGGGTTCAGCTGCGTCGAGATGCAGGAACAGAGAGCCTGGACGTTTCAGGCTGACACTTACGGCCTCTGCGTCATCGCGCACATGATGCTACATGGGACGCAGATGAGCATCCAGAAGACGCCCAGGCCCGATGGAAGCTACATGTACCAGCCCACATCGCCGTTCAAAAGGTACTGGAACGTGGAGCTGTGGAAAAACCTCTTCTCCACGCTGCTCAACGCGACCTCCAACGGCAGCGACGCGGCCGTGCTCCGGAGCCTCCGGATGTCCTTCCAGGAGTACCTGTGCAGCAACCGGCAGCTCGTCGGCAAGCTGAACCAGCAACTGGCCAAGCAGAAGACCTCCCTGTGCCTATCCTGACCGAGACATATACGCATCTCGCGTTTCATCCTCATCATTTTTCCCGATTCCCTCGTGTTGCCTGTGTGTAAAGTGGTGGAGTATAAGATACCTTCCGTAACTTCGTAGCACTTCCTCTGTGCGTGCGTGTGCAGCAGTAATTAACGTGCCACATCTCCACTTTGAAAGCTGAAACATCTACTATTGGGCCAGATGGAAATTTCGTACAGTATCTTCTTCTCCAA
CDS Sequence
  • >LOC_Os07g32480.1
    ATGAATAATTTATTGGAGAACATTAATGTTGATCTGAAGAAGTTCGCTGGCTATCATAAGAGCAATAAGGTCTATCATGGAAAGGTGCCATTAACTTCGCCTCAGAATGTTTTAAGAAACAAAGTCATTGAATTAGGTGGTAGAAAGTACCAGATCAAAGGTTCTCCTGGTACTGGTGCTTTTGCAAAAGTTTACAAAGCCAGTGTCGATGGTAATACAGAAGACCTGGTTGCTTTAAAGATTCAGAAACCACCATTTCCTTGGGAATTTTACATGTATCGCCAGCTTGATACGCGCGTATCTGATATTGAGAGACCAAGCTTTGGCTACACTCATGAAGTGCATGTATACGCTGATGTCAGTGTGCTTGTTTGTGATTACCTGCCATACGGAACTCTTCTGGATGTTATAAATTCTCATCTAGTACTTGAACGCCATATGGATGAAGTTCTATGCATATATTACACTATAGAGATGCTGCGCATGTTGGAAACACTGCACAGCGTTGGCATAATTCATGGTGATTTCAAGCCTGACAATATGCTTGTTTGCTACCCAAGTGGAGAAATCACAGACGAAACCTTCAAAGGCGAGACAAGATCCGAGCGGAATCAGGGGCTCTGCCTTGTTGACTGGGGCCGTGGCATCGACCTGAACCTCTTCCCATCCGGTGCGGAGTTCTACGGCGACTGCCGAACCTCCGGGTTCAGCTGCGTCGAGATGCAGGAACAGAGAGCCTGGACGTTTCAGGCTGACACTTACGGCCTCTGCGTCATCGCGCACATGATGCTACATGGGACGCAGATGAGCATCCAGAAGACGCCCAGGCCCGATGGAAGCTACATGTACCAGCCCACATCGCCGTTCAAAAGGTACTGGAACGTGGAGCTGTGGAAAAACCTCTTCTCCACGCTGCTCAACGCGACCTCCAACGGCAGCGACGCGGCCGTGCTCCGGAGCCTCCGGATGTCCTTCCAGGAGTACCTGTGCAGCAACCGGCAGCTCGTCGGCAAGCTGAACCAGCAACTGGCCAAGCAGAAGACCTCCCTGTGCCTATCCTGA
Protein Sequence
  • >LOC_Os07g32480.1
    MNNLLENINVDLKKFAGYHKSNKVYHGKVPLTSPQNVLRNKVIELGGRKYQIKGSPGTGAFAKVYKASVDGNTEDLVALKIQKPPFPWEFYMYRQLDTRVSDIERPSFGYTHEVHVYADVSVLVCDYLPYGTLLDVINSHLVLERHMDEVLCIYYTIEMLRMLETLHSVGIIHGDFKPDNMLVCYPSGEITDETFKGETRSERNQGLCLVDWGRGIDLNLFPSGAEFYGDCRTSGFSCVEMQEQRAWTFQADTYGLCVIAHMMLHGTQMSIQKTPRPDGSYMYQPTSPFKRYWNVELWKNLFSTLLNATSNGSDAAVLRSLRMSFQEYLCSNRQLVGKLNQQLAKQKTSLCLS*