Gene Details:

• MSU gene ID: LOC_Os07g28820
• RAPdb gene ID: Os07g0471000
• Gene Symbol: IRE1 OsIRE1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• The endoplasmic reticulum (ER) stress sensor IRE1 transduces signals by inducing the unconventional splicing of mRNAs encoding key transcription factors: HAC1 in yeast and XBP1 in animals.
• This study demonstrates that the Oryza sativa (rice) OsbZIP50 transcription factor, an orthologue of Arabidopsis AtbZIP60, is regulated by IRE1-mediated splicing of its RNA.
• OsbZIP50 mRNA is spliced in a similar manner to HAC1 and XBP1 mRNAs; however, this splicing has very different effects on the translation products, a finding that shows the diversity of IRE1-related transcription factors in eukaryotes.

Function-related keywords:

• transcription-factor

Literature:

• Cis-element of the rice PDIL2-3 promoter is responsible for inducing the endoplasmic reticulum stress response .  DOI:  10.1016/j.jbiosc.2013.10.023 ;  PMID:  24315532
• Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice .  DOI:  10.1007/s00425-012-1714-y ;  PMID:  22824965
• Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice .  DOI:  10.1111/j.1365-313X.2011.04844.x ;  PMID:  22050533
• Conservation of IRE1-regulated bZIP74 mRNA unconventional splicing in rice (Oryza sativa L.) involved in ER stress responses .  DOI:  10.1093/mp/ssr115 ;  PMID:  22199238
• Isolation and characterization of a putative transducer of endoplasmic reticulum stress in Oryza sativa .  DOI:  10.1093/pcp/pcf063 ;  PMID:  12040100
• Multiple roles of the ER stress sensor IRE1 demonstrated by gene targeting in rice .  DOI:  10.1038/srep00944 ;  PMID:  23230509

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: