Gene Details:

• MSU gene ID: LOC_Os07g22710
• RAPdb gene ID: Os07g0409900
• Gene Symbol: OsCPK18
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• We previously reported that rice CALCIUM-DEPENDENT PROTEIN KINASE 18 (OsCPK18) and MITOGEN-ACTIVATED PROTEIN KINASE 5 (OsMPK5) mutually phosphorylate each other and that OsCPK18 phosphorylates and positively regulates OsMPK5 to suppress rice immunity.
• In vitro and in vivo kinase assays demonstrated that OsMPK5 phosphorylates C-terminal threonine (T505) and serine (S512) residues of OsCPK18 and OsCPK4, respectively.
• The kinase activity of OsCPK18(T505D) , in which T505 was replaced by aspartic acid to mimic T505 phosphorylation, displayed less calcium sensitivity than that of wild-type OsCPK18.
• Interestingly, editing the MAPK phosphorylation motif in OsCPK18 and its paralog OsCPK4, which deprives OsMPK5-mediated phosphorylation but retains calcium-dependent activation of kinase activity, simultaneously increases rice yields and immunity.
• In this study, we found that OsCPK18 and its paralog OsCPK4 positively regulate plant height and yield-related traits.

Function-related keywords:

• Kinase ,  kinase ,  immunity ,  height ,  plant-height ,  protein-kinase ,  calcium

Literature:

• Fine-tuning OsCPK18/OsCPK4 activity via genome editing of phosphorylation motif improves rice yield and immunity .  DOI:  10.1111/pbi.13905 ;  PMID:  35984919

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: