Gene Details:

• MSU gene ID: LOC_Os07g10390
• RAPdb gene ID: Os07g0203700
• Gene Symbol: spl5 SF3b3
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• ) spotted leaf 5 (spl5) indicates that wild-type spl5 negatively regulates cell death and resistance responses.
• Bioinformatic analysis showed that SPL5 gene encodes a putative splicing factor 3b subunit 3 (SF3b3) and might be involved in splicing reactions of pre-mature RNAs participating in the regulation of cell death and resistance responses.
• The data presented here clearly indicate that the spl5 negatively regulates cell death and resistance responses via modulating RNA splicing in plants.
• SPL5, a cell death and defense-related gene, encodes a putative splicing factor 3b subunit 3 (SF3b3) in rice.
• Rice mutant, spl5 (spotted leaf 5), has spontaneous hypersensitive-like lesions on its leaves and shows enhanced resistance to pathogens, indicating that spl5 plays a role in programmed cell death (PCD) and disease resistance.
• Since the serotonin plays a critical role in inducing disease-resistance, the increased serotonin level may contribute, at least partly, to the disease resistance in spl5.
• The spl5 gene may act as a negative regulatory factor activating the serotonin metabolic pathway, and these results might provide a new insight into the spl5-induced defense response mechanisms in plants.
• Interestingly, according to our microarray and real-time PCR assays, the expressions of a transcription factor OsWRKY14 and genes responsible for the biosynthesis of serotonin, anthranilate synthase (AS), indole-3-glycerolphosphate synthase (IGPS), tryptophan synthase (TS) and tryptophan decarboxylase (TDC) were significantly up-regulated in the spl5 mutant.
• Transcriptome profiling of the spl5 mutant reveals that spl5 has a negative role in the biosynthesis of serotonin for rice disease resistance.
• A 1.84-Mb region on rice chromosome 2 carrying SPL4, spl5 and MLO8 genes is associated with higher yield under phosphorus-deficient acidic soil.

Function-related keywords:

• cell-death ,  leaf ,  defense ,  resistance ,  transcription-factor ,  defense-response ,  disease ,  disease-resistance ,  yield

Literature:

• SPL5, a cell death and defense-related gene, encodes a putative splicing factor 3b subunit 3 (SF3B3) in rice .  DOI:  10.1007/s11032-011-9677-4
• Transcriptome profiling of the spl5 mutant reveals that SPL5 has a negative role in the biosynthesis of serotonin for rice disease resistance .  DOI:  10.1186/s12284-015-0052-7 ;  PMID:  26029330
• A 1.84-Mb region on rice chromosome 2 carrying SPL4, SPL5 and MLO8 genes is associated with higher yield under phosphorus-deficient acidic soil .  DOI:  10.1007/s13353-020-00601-4 ;  PMID:  33409935

Related News:

Gene Resources:

• NCBI ID: P0431A02.16
• UniProt accessions:

Sequences: