Gene Details:

• MSU gene ID: LOC_Os06g48060
• RAPdb gene ID: Os06g0695800
• Gene Symbol: STAR1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• A yeast one-hybrid assay showed that ART1 has a transcriptional activation potential and interacts with the promoter region of STAR1, an important factor in rice Al tolerance.
• Microarray analysis revealed 31 downstream transcripts regulated by ART1, including STAR1 and 2 and a couple of homologs of Al tolerance genes in other plants.
• Both STAR1 and STAR2 are expressed mainly in the roots and are specifically induced by Al exposure.
• Expression in onion epidermal cells, rice protoplasts, and yeast showed that STAR1 interacts with STAR2 to form a complex that localizes to the vesicle membranes of all root cells, except for those in the epidermal layer of the mature zone.
• Furthermore, addition of exogenous UDP-glucose rescued root growth in the STAR1 mutant exposed to Al.
• Here, we report that two genes, STAR1 (for sensitive to Al rhizotoxicity1) and STAR2, are responsible for Al tolerance in rice.
• STAR1 encodes a nucleotide binding domain, while STAR2 encodes a transmembrane domain, of a bacterial-type ATP binding cassette (ABC) transporter.
• These results indicate that STAR1 and STAR2 form a complex that functions as an ABC transporter, which is required for detoxification of Al in rice.

Function-related keywords:

• Al-tolerance ,  root ,  transporter ,  growth

Literature:

• A bacterial-type ABC transporter is involved in aluminum tolerance in rice .  DOI:  10.1105/tpc.108.064543 ;  PMID:  19244140
• A zinc finger transcription factor ART1 regulates multiple genes implicated in aluminum tolerance in rice .  DOI:  10.1105/tpc.109.070771 ;  PMID:  19880795

Related News:

Gene Resources:

• NCBI ID: AB253626
• UniProt accessions:

Sequences: