Gene Details:

• MSU gene ID: LOC_Os06g38470
• RAPdb gene ID: Os06g0583400
• Gene Symbol: OsHDAC1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• The overexpression leads to a range of novel phenotypes, involving increased growth rate and altered plant architecture, suggesting that OsHDAC1 functions in the genome-wide programming of gene expression.
• Structure and expression of the rice class-I type histone deacetylase genesOsHDAC1-3:OsHDAC1overexpression in transgenic plants leads to increased growth rate and altered architecture.
• We have previously isolated a rice gene encoding a histone deacetylase, OsHDAC1, and observed that its transgenic overexpression increases seedling root growth.
• To identify the transcriptional repression events that occur as a result of OsHDAC1 overexpression (OsHDAC1(OE)), a global profiling of root-expressed genes was performed on OsHDAC1(OE) or HDAC inhibitor-treated non-transgenic (NT) roots, in comparison with untreated NT roots.
• We selected 39 genes that are induced and repressed in HDAC inhibitor-treated NT and OsHDAC1(OE) roots, compared with NT roots, respectively.
• The root phenotype of OsNAC6 knock-out seedlings was observed to be similar to that of the OsHDAC1(OE) seedlings.
• Conversely, the root phenotype of the OsNAC6 overexpressors was similar to that of the OsHDAC1 knock-out seedlings.
• These observations indicate that OsHDAC1 negatively regulates the OsNAC6 gene that primarily mediates the alteration in the root growth of the OsHDAC1(OE) seedlings.
• The histone deacetylase OsHDAC1 epigenetically regulates theOsNAC6gene that controls seedling root growth in rice.
• OsHDAC1 was expressed at similar levels in the leaves, roots, and callus cells, whereas OsHDAC2 and 3 were expressed in the roots and callus cells, but not in the leaves, exhibiting distinct tissue specificity.
• Rice OsHDAC1 RNAi plants produced fewer lateral roots than wild-type plants, whereas plants overexpressing OsHDAC1 exhibited increased lateral root proliferation by promoting LR primordia formation.
• Our findings suggest that OsHDAC1 is a breeding target in rice that can improve resource capture.

Function-related keywords:

• growth ,  root ,  seedling ,  architecture ,  breeding ,  lateral-root

Literature:

• Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture .  DOI:  10.1046/j.1365-313x.2003.01650.x ;  PMID:  12581311
• The histone deacetylase OsHDAC1 epigenetically regulates the OsNAC6 gene that controls seedling root growth in rice .  DOI:  10.1111/j.1365-313X.2009.03908.x ;  PMID:  19453457
• Histone deacetylase HDA710 controls salt tolerance by regulating ABA signaling in rice .  DOI:  10.1111/jipb.13042 ;  PMID:  33289304
• The histone deacetylase 1/GSK3/SHAGGY-like kinase 2/BRASSINAZOLE-RESISTANT 1 module controls lateral root formation in rice .  DOI:  10.1093/plphys/kiac015 ;  PMID:  35078247

Related News:

Gene Resources:

• NCBI ID: AF513382
• UniProt accessions:

Sequences: