Gene Details:

Functional Descriptions:

  • In this study, we identified a rice Cd transporter, OsLCT1, involved in Cd transport to the grains.
  • Low-affinity cation transporter (OsLCT1) regulates cadmium transport into rice grains.
  • The knockdown plants of OsLCT1 accumulated approximately half as much Cd in the grains as did the control plants.
  • The content of other metals in rice grains and plant growth were not negatively affected by OsLCT1 suppression.
  • These results suggest that OsLCT1 functions at the nodes in Cd transport into grains and that in a standard japonica cultivar, the regulation of OsLCT1 enables the generation of low-Cd rice without negative effects on agronomical traits.
  • In rice plants, strong OsLCT1 expression was observed in leaf blades and nodes during the reproductive stage.
  • RNAi-mediated knockdown of OsLCT1 did not affect xylem-mediated Cd transport but reduced phloem-mediated Cd transport.
  • In the uppermost node, OsLCT1 transcripts were detected around large vascular bundles and in diffuse vascular bundles.
  • The OsHMA2, OsLCT1 and OsZIP3 transporters were all involved in zinc (Zn) and cadmium (Cd) transport.
  • Furthermore, the expression of the Cd transporter genes, OsHMA2, OsHMA3 and OsLCT1 were curtailed in NPs-treated rice plants under normal and drought stress conditions.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Sequences:

cDNA Sequence
  • >LOC_Os06g38120.1
    ATGACCGGCGAGGCAAGCAAAGGTCGGAGTGGAGGCGGCCGAGAGGGACGCGCATCGTCCTCCCGGCAGCGCACCGATGTTGCTAGTGAACTAGAACTACAAGAAGCATCAAGCTCCGCGGTTTCGCCGCCGCACCCGAACCCCGGCGACGCGGAGGCGGCACCGGCCGCCGTCGCGATCCCGCCGGCGCCCGCACCCCTTCATGACCTGGCCCAAGGTGCGGAGGCCGCTTCTGCAGCGGGGAGGAGTAACGAGAAGGAGGAACAAGTAGAACTCCGCAAGGTCCAGAAGGATATCGAGTTAGGGGCACTTGTTGCCGGCTTCTCCTTCTCCGTGGCGATGACCGGCTTCTTCCTCAGCCCGCAAGCGACGGGGCGGCAAGCCATATACATCGACATCTCGATGTTCCTCGCCTTCTCATCTTTCGTCTGTGGCTGTACGTTCATGTTGCTGAGAATGCAGCGGCTCAGCGCCAGGGAGGAGCACATCTCTGGCTTCCACCACGCCATCTCCAAGTGCCTCTTCTATCTTTGCTGCGTTCTACCGGTGCTGACAATACTTTGTCTGCTGCTGGTTATGCCGCGCAAGCCTTACATCTACGTAGGACTCGGCGTCCTCGCGGCGGCCGTGGTGCCGGTGGCCCTCATGCACTGGTACGTGAGCCGCAAGACCCAGCTGGAAACCAACGACACGGCACCTGAGGATGTTGAGCAGAATGCAATGAGCCGCAAGACCCAGGAAACCAACGGCACGGCGCCTGAGGACGACGATGAGCAGAAGGCGATGGAGTCCAGCTATAAGATCACCTCGGCCATCGTCCCCATGTCGTTGGCGGGCCTCGTCGGCGTGCTCTTCGGCGTCTACAAGGGGGGCAGCAGCAGTGGAGGCGCCGGCGGCGACATCTCCGGCTCTGTCCACGTCGTCATCATGTGCATGTTCATCACCTCGATGTTAAGCATGCTCCTGATGATGCTGTGGATGAAGGTCCTGGAGAGCAAGAAACCGAAGCTCCGGGAGTTCTTCGTCAGAGCTACTATCCCGCGTGCCAATGCGGCCCTTCTAGCCTTGCTCGCGATCGCCGCCTTCGCCGCGTCGTTTGGGATCCTCAGGTGGTACATGGTAGCCGCGTTCCTGACTCTCGCCTTGGCTGCCACCGTCCAATTCGTCATCCAGCACTGCACCAGAGAGCAGAATGCCGTGCGAGCTAGCCACAACGAGACGCAGCTCAAGTGGATGGCGGACATGGCGAGCAAGACGACACCGTGGTCTCTGGGGATAGTCATGGCGATCTTTGGAGGCTTTCTTGGAGACGATGATAAAAGCAAGGACAAGATGGTGGCCCTTAAGGTCTGCATGTTCTTATCGACCTCGGCGTTCACGTCGGGCCTTGGGCTCATGTACCTGACCATGCGACCGGGAGAGTCAGCCAGAGGAGGTACCTCCAAAGCGGCCATGACCATACTGGCTTGGTCTGTCATGGTGTTGCTTTCTGCAGCCGCGCTTGCTATCTATGGCGTCGAAGTTATGAAGTCATAGCATGCGTGCATGAAGAAGGGAAAATTTAGCAGCTGAAGATGGCAAAAGATGAAAAGAATACGCACCTGAAGAAAGAAGGTGCCACCAGAGTTGACCTCACCTGCCTCCCCATTTTAAACTCTATCAATTTCCACCCTTTGGACCAATGTAGAAAGGGGCAATAATGCTTGCATTTTTAAAGCAGGCCCTCCTACTCCCTCCGGGCTGATAATATTGAGAAAATCTATTGTGTACCCTGAAATTTTAGCTAATCCCTTCTATACCCTTAAATTTTGCTTACTTGTGTAAAATCAAAGTGTGTTTGATTATTATTCTGTGATGAACAATTGGCATCTGAGATTATTGGTTTTGATA
CDS Sequence
  • >LOC_Os06g38120.1
    ATGACCGGCGAGGCAAGCAAAGGTCGGAGTGGAGGCGGCCGAGAGGGACGCGCATCGTCCTCCCGGCAGCGCACCGATGTTGCTAGTGAACTAGAACTACAAGAAGCATCAAGCTCCGCGGTTTCGCCGCCGCACCCGAACCCCGGCGACGCGGAGGCGGCACCGGCCGCCGTCGCGATCCCGCCGGCGCCCGCACCCCTTCATGACCTGGCCCAAGGTGCGGAGGCCGCTTCTGCAGCGGGGAGGAGTAACGAGAAGGAGGAACAAGTAGAACTCCGCAAGGTCCAGAAGGATATCGAGTTAGGGGCACTTGTTGCCGGCTTCTCCTTCTCCGTGGCGATGACCGGCTTCTTCCTCAGCCCGCAAGCGACGGGGCGGCAAGCCATATACATCGACATCTCGATGTTCCTCGCCTTCTCATCTTTCGTCTGTGGCTGTACGTTCATGTTGCTGAGAATGCAGCGGCTCAGCGCCAGGGAGGAGCACATCTCTGGCTTCCACCACGCCATCTCCAAGTGCCTCTTCTATCTTTGCTGCGTTCTACCGGTGCTGACAATACTTTGTCTGCTGCTGGTTATGCCGCGCAAGCCTTACATCTACGTAGGACTCGGCGTCCTCGCGGCGGCCGTGGTGCCGGTGGCCCTCATGCACTGGTACGTGAGCCGCAAGACCCAGCTGGAAACCAACGACACGGCACCTGAGGATGTTGAGCAGAATGCAATGAGCCGCAAGACCCAGGAAACCAACGGCACGGCGCCTGAGGACGACGATGAGCAGAAGGCGATGGAGTCCAGCTATAAGATCACCTCGGCCATCGTCCCCATGTCGTTGGCGGGCCTCGTCGGCGTGCTCTTCGGCGTCTACAAGGGGGGCAGCAGCAGTGGAGGCGCCGGCGGCGACATCTCCGGCTCTGTCCACGTCGTCATCATGTGCATGTTCATCACCTCGATGTTAAGCATGCTCCTGATGATGCTGTGGATGAAGGTCCTGGAGAGCAAGAAACCGAAGCTCCGGGAGTTCTTCGTCAGAGCTACTATCCCGCGTGCCAATGCGGCCCTTCTAGCCTTGCTCGCGATCGCCGCCTTCGCCGCGTCGTTTGGGATCCTCAGGTGGTACATGGTAGCCGCGTTCCTGACTCTCGCCTTGGCTGCCACCGTCCAATTCGTCATCCAGCACTGCACCAGAGAGCAGAATGCCGTGCGAGCTAGCCACAACGAGACGCAGCTCAAGTGGATGGCGGACATGGCGAGCAAGACGACACCGTGGTCTCTGGGGATAGTCATGGCGATCTTTGGAGGCTTTCTTGGAGACGATGATAAAAGCAAGGACAAGATGGTGGCCCTTAAGGTCTGCATGTTCTTATCGACCTCGGCGTTCACGTCGGGCCTTGGGCTCATGTACCTGACCATGCGACCGGGAGAGTCAGCCAGAGGAGGTACCTCCAAAGCGGCCATGACCATACTGGCTTGGTCTGTCATGGTGTTGCTTTCTGCAGCCGCGCTTGCTATCTATGGCGTCGAAGTTATGAAGTCATAG
Protein Sequence
  • >LOC_Os06g38120.1
    MTGEASKGRSGGGREGRASSSRQRTDVASELELQEASSSAVSPPHPNPGDAEAAPAAVAIPPAPAPLHDLAQGAEAASAAGRSNEKEEQVELRKVQKDIELGALVAGFSFSVAMTGFFLSPQATGRQAIYIDISMFLAFSSFVCGCTFMLLRMQRLSAREEHISGFHHAISKCLFYLCCVLPVLTILCLLLVMPRKPYIYVGLGVLAAAVVPVALMHWYVSRKTQLETNDTAPEDVEQNAMSRKTQETNGTAPEDDDEQKAMESSYKITSAIVPMSLAGLVGVLFGVYKGGSSSGGAGGDISGSVHVVIMCMFITSMLSMLLMMLWMKVLESKKPKLREFFVRATIPRANAALLALLAIAAFAASFGILRWYMVAAFLTLALAATVQFVIQHCTREQNAVRASHNETQLKWMADMASKTTPWSLGIVMAIFGGFLGDDDKSKDKMVALKVCMFLSTSAFTSGLGLMYLTMRPGESARGGTSKAAMTILAWSVMVLLSAAALAIYGVEVMKS*